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    SYSTEMS AND METHODS FOR SEPARATING IONS AT ABOUT OR ABOVE ATMOSPHERIC PRESSURE
    82.
    发明申请
    SYSTEMS AND METHODS FOR SEPARATING IONS AT ABOUT OR ABOVE ATMOSPHERIC PRESSURE 审中-公开

    公开(公告)号：US20200321208A1

    公开(公告)日：2020-10-08

    申请号：US16907510

    申请日：2020-06-22

    Applicant: Purdue Research Foundation

    Inventor： Robert Graham Cooks ,  Dalton Snyder ,  Amar S. Basu ,  Wen-Ping Peng

    IPC: H01J49/42 ,  G01N27/62 ,  H01J49/00 ,  H01J49/16

    Abstract: The invention generally relates to systems and methods for separating ions at about or above atmospheric pressure. In certain embodiments, the invention provides systems that include an ionization source that generates ions and an ion trap. The ion trap is maintained at about or above atmospheric pressure and includes a plurality of electrodes and at least one inlet configured to receive a gas flow and at least one outlet. The system is configured such that a combination of a gas flow and one or more electric fields produced by the electrodes separates the ions based on mass-to-charge ratio and sends the separated ions through the at least one outlet of the ion trap.

    Ion focusing
    84.
    发明授权
    Ion focusing 有权

    公开(公告)号：US10777400B2

    公开(公告)日：2020-09-15

    申请号：US16803023

    申请日：2020-02-27

    Applicant: Purdue Research Foundation

    Inventor： Robert Graham Cooks ,  Zane Baird ,  Wen-Ping Peng

    IPC: H01J49/06 ,  H01J49/10 ,  H01J49/16 ,  H01J49/26

    Abstract: The invention generally relates to apparatuses for focusing ions at or above ambient pressure and methods of use thereof. In certain embodiments, the invention provides an apparatus for focusing ions that includes an electrode having a cavity, at least one inlet within the electrode configured to operatively couple with an ionization source, such that discharge generated by the ionization source is injected into the cavity of the electrode, and an outlet. The cavity in the electrode is shaped such that upon application of voltage to the electrode, ions within the cavity are focused and directed to the outlet, which is positioned such that a proximal end of the outlet receives the focused ions and a distal end of the outlet is open to ambient pressure.

    Systems and methods for ejection of ions from an ion trap
    87.
    发明授权
    Systems and methods for ejection of ions from an ion trap 有权

    公开(公告)号：US10515792B2

    公开(公告)日：2019-12-24

    申请号：US15920900

    申请日：2018-03-14

    Applicant: Purdue Research Foundation

    Inventor： Robert Graham Cooks ,  Dalton Snyder

    IPC: H01J49/42 ,  H01J49/00

    Abstract: The invention generally relates to systems and methods for ejection of ions from an ion trap. In certain embodiments, systems and methods of the invention sum two different frequency signals into a single summed signal that is applied to an ion trap. In other embodiments, an amplitude of a single frequency signal is modulated as the single frequency signal is being applied to the ion trap. In other embodiments, a first alternating current (AC) signal is applied to an ion trap that varies as a function of time, while a constant radio frequency (RF) signal is applied to the ion trap.

    Systems and methods for relay ionization
    88.
    发明授权
    Systems and methods for relay ionization 有权

    公开(公告)号：US10395911B2

    公开(公告)日：2019-08-27

    申请号：US16265514

    申请日：2019-02-01

    Applicant: Purdue Research Foundation

    Inventor： Robert Graham Cooks ,  Anyin Li ,  Adam Hollerbach

    IPC: H01J49/00 ,  H01J49/04 ,  H01J49/16

    Abstract: The invention generally relates to systems and methods for relay ionization of a sample. In certain aspects, the invention provides systems that include an ion source that generates ions, a sample emitter configured to hold a sample, and a mass spectrometer. The system is configured such that the ions generated by the ion source are directed to interact with the sample emitter, thereby causing the sample to be discharged from the sample emitter and into the mass spectrometer.

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