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416 条记录 (耗时 0.042 秒)

    Method for manufacturing a heat generating apparatus
    81.
    发明授权
    Method for manufacturing a heat generating apparatus 有权
    制造发热装置的方法

    公开(公告)号：US06453648B1

    公开(公告)日：2002-09-24

    申请号：US09347963

    申请日：1999-07-06

    申请人： Jie Zhang ,  Hao Zhang ,  Larry Rigby ,  Wade A. Hull

    发明人： Jie Zhang ,  Hao Zhang ,  Larry Rigby ,  Wade A. Hull

    IPC分类号： A61F700

    CPC分类号： A61F7/034 ,  A61F2007/0226 ,  A61F2007/0249

    摘要： The present invention relates to a method for manufacturing a heating device which is capable of generating heat when exposed to oxygen. The heat generating element comprises activated carbon and iron is used to generate an exothermic oxidation reaction within the heating device. Introducing an oxidation inhibitor during the manufacturing process allows the manufacturing of the device to take place in ambient atmospheric conditions. The present invention also includes a loading facilitator which allows the heat generating medium to be more easily and efficiently loaded into the heat generating device. When appropriate, the oxidation inhibitor and loading facilitator can be removed.

    摘要翻译： 本发明涉及一种能够在暴露于氧气时产生热量的加热装置的制造方法。 发热元件包括活性炭和铁，用于在加热装置内产生放热氧化反应。 在制造过程中引入氧化抑制剂可使装置的制造在环境大气条件下进行。 本发明还包括能够使发热介质更容易且有效地装载到发热装置中的负载辅助装置。 适当时，可以除去氧化抑制剂和负载促进剂。

    Alkoxy-substituted compounds, methods and compositions for inhibiting parp activity
    83.
    发明授权
    Alkoxy-substituted compounds, methods and compositions for inhibiting parp activity 失效
    烷氧基取代的化合物，用于抑制parp活性的方法和组合物

    公开(公告)号：US06426415B1

    公开(公告)日：2002-07-30

    申请号：US09079508

    申请日：1998-05-15

    申请人： Paul F. Jackson ,  Keith M. Maclin ,  Jie Zhang

    发明人： Paul F. Jackson ,  Keith M. Maclin ,  Jie Zhang

    IPC分类号： C07D23730

    CPC分类号： C07D471/06 ,  C07D217/22 ,  C07D217/24 ,  C07D221/12 ,  C07D221/18 ,  C07D237/30 ,  C07D237/32 ,  C07D237/34 ,  C07D239/88 ,  C07D239/93 ,  C07D239/94 ,  C07D475/02 ,  C07D491/04 ,  C07F9/6561

    摘要： A compound of formula I: or a pharmaceutically acceptable salt, prodrug, metabolite, optical isomer or stereoisomer thereof, wherein: R1, when present, is hydrogen or lower alkyl; R2 is lower alkyl, aryl, aralkyl, lower alkanoyl, or —(CH2)n—(CHOH)y(CH2)mA, wherein n is 1-4, y is 0 or 1, m is 0-5, and A is cycloalkyl, cycloalkenyl, lower alkanoyl, aryl, aralkyl, —NH2, —NH-(lower alkyl), Y represents the atoms necessary to form a fused 5- to 6-membered ring that is aromatic or nonaromatic and carbocyclic or heterocyclic; Z is (i) —CHR2CHR3— where R2 and R3 are independently hydrogen, alkyl, aryl or aralkyl; (ii) —R6C═CR3— where R6 and R3 are independently hydrogen, lower alkyl, aryl, aralkyl, chlorine, bromine or —NR7R8, where R7 and R8 are independently hydrogen or lower alkyl, or, R6 and R3, taken together, form a fused 5- to 6-membered ring that is aromatic or nonaromatic and carbocyclic or heterocyclic; (iii) —R2C═N—; (iv) —CR2(OH)—NR7—; or (v) —C(O)—NR7—.

    摘要翻译： 式I的化合物或其药学上可接受的盐，前药，代谢物，旋光异构体或立体异构体，其中：当存在时，R 1为氢或低级烷基; R 2为低级烷基，芳基，芳烷基，低级烷酰基或 - （ CH2）n-（CHOH）y（CH2）mA，其中n为1-4，y为0或1，m为0-5，A为环烷基，环烯基，低级烷酰基，芳基，芳烷基，-NH2， NH-（低级烷基），Y表示形成芳族或非芳族和碳环或杂环的稠合5-至6-元环所必需的原子; Z为（i）-CHR2CHR3-，其中R2和R3独立地为氢，烷基 ，芳基或芳烷基;（ii）-R6C = CR3-，其中R6和R3独立地为氢，低级烷基，芳基，芳烷基，氯，溴或-NR7R8，其中R7和R8独立地为氢或低级烷基，或R6和 R 3一起形成芳族或非芳族和碳环或杂环的稠合的5-至6-元环;（iii）-R2C = N - ;（iv）-CR2（OH）-NR7-; 或（ⅴ）-C（O）-NR7-。

    Heating stove
    86.
    外观设计
    Heating stove 有权

    公开(公告)号：USD1028195S1

    公开(公告)日：2024-05-21

    申请号：US29832191

    申请日：2022-03-25

    申请人： Jie Zhang

    设计人： Jie Zhang

    摘要： FIG. 1 is a perspective view of a heating stove, showing my new design;
    FIG. 2 is another perspective view thereof;
    FIG. 3 is a front view thereof;
    FIG. 4 is a rear view thereof;
    FIG. 5 is a left side view thereof;
    FIG. 6 is a right side view thereof;
    FIG. 7 is a top plan view thereof;
    FIG. 8 is a bottom plan view thereof; and,
    FIG. 9 is an enlarged view of portion of FIG. 1.
    The dash-dash broken line showing of the heating stove is for the purpose of illustrating the article and forms no part of the claimed design. The dot-dash broken lines shown in FIGS. 1 & 9 define the boundary of the enlargement area and form no part of the claimed design.

    Web development system
    87.
    发明授权
    Web development system 有权

    公开(公告)号：US09904522B2

    公开(公告)日：2018-02-27

    申请号：US15038602

    申请日：2014-11-24

    申请人： Jie Zhang ,  Xun Shao

    发明人： Jie Zhang ,  Xun Shao

    IPC分类号： G06F9/44 ,  G06F17/30 ,  G06F3/048 ,  G06F3/00 ,  G06F9/455 ,  G06F9/445

    CPC分类号： G06F8/31 ,  G06F8/30 ,  G06F8/65 ,  G06F8/656 ,  G06F9/45529

    摘要： The present invention provides a web development system. In a running state of a web application being developed, the development system generates or modifies a script code used to perform a predetermined function. The development system includes a script parser that parses the generated script code or the modified script code to correspondingly generate an object type which performs a new function, or to modify the object type which performs an existing function. The development system also includes an object manager that generates a new function object or modifies the existing function object according to the generated object type and organizes the invoking relationships between the new or modified function object and other objects, so as to generate or modify the predetermined function when the web application is operating.

    Apparatus and procedure for in vitro measurement of a substance, nicotine, released from a smokeless tobacco product
    89.
    发明授权
    Apparatus and procedure for in vitro measurement of a substance, nicotine, released from a smokeless tobacco product 有权
    用于体外测量从无烟烟草制品释放的物质，尼古丁的装置和程序

    公开(公告)号：US09464972B2

    公开(公告)日：2016-10-11

    申请号：US13041217

    申请日：2011-03-04

    申请人： Jian-Ping Xie ,  Ryan Q. Meng ,  Jie Zhang ,  Yong-Li Zong ,  Peng Li

    发明人： Jian-Ping Xie ,  Ryan Q. Meng ,  Jie Zhang ,  Yong-Li Zong ,  Peng Li

    IPC分类号： G01N1/22 ,  G01N1/40 ,  G01N30/88 ,  G01N33/94

    CPC分类号： G01N1/405 ,  G01N30/88 ,  G01N33/9406 ,  G01N2030/884

    摘要： An apparatus (100) and method for measuring an extract (1000) released from a product sample (330) in vitro. The apparatus (100) comprising an in vitro environment which simulates an in vivo environment. The apparatus (100) contains a product sample (330) with the product sample (330) exposed to the in vitro environment. An extract (1000) is produced from the product sample (330) when the product sample (330) is subjected to the in vitro environment. The extract (1000) is analyzed to determine the amount of at least one element in the extract and the rate of release of at least one element in the product sample (330). The product sample is a smokeless tobacco product. An element analyzed for is nicotine.

    摘要翻译： 一种用于在体外测量从产品样品（330）释放的提取物（1000）的装置（100）和方法。 该装置（100）包括模拟体内环境的体外环境。 装置（100）包含与产品样品（330）暴露于体外环境的产品样品（330）。 当产品样品（330）经受体外环境时，从产品样品（330）产生提取物（1000）。 分析提取物（1000）以确定萃取物中至少一种元素的量和产物样品（330）中至少一种元素的释放速率。 产品样品是无烟烟草制品。 分析的元素是尼古丁。