公开(公告)号：US08107067B2

公开(公告)日：2012-01-31

申请号：US12043434

申请日：2008-03-06

Applicant: Anthony C. Gilby

Inventor： Anthony C. Gilby

IPC: G01N1/10

CPC classification number: G01N21/552 ,  G01N21/0303 ,  G01N21/05 ,  G01N30/74 ,  G01N2021/0346 ,  G01N2021/052 ,  G01N2201/064

Abstract: The present invention is directed to the use of a light absorbing wall material to eliminate stray light paths in light-guiding structures, such as those used for HPLC absorbance detection. More specifically, the present invention relates to the use of carbon-doped Teflon® AF, or “black Teflon® AF,” for all or part of the walls of a light-guiding flowcell adapted for use in HPLC absorbance detection.

Abstract translation: 本发明涉及使用光吸收壁材料来消除导光结构中的杂散光路径，例如用于HPLC吸光度检测的那些。 更具体地，本发明涉及适用于HPLC吸光度检测的导光流动池的全部或部分壁的碳掺杂Teflon AF或“黑色Teflon AF”的用途。

公开(公告)号：US20080106737A1

公开(公告)日：2008-05-08

申请号：US12005396

申请日：2007-12-27

Applicant: Amnon Weichselbaum ,  Jaime De La Zerda ,  Issakhar Regev

Inventor： Amnon Weichselbaum ,  Jaime De La Zerda ,  Issakhar Regev

IPC: G01N21/00 ,  G01N1/10

CPC classification number: G01N21/51 ,  G01N21/0303 ,  G01N33/493 ,  G01N2021/0382 ,  G01N2021/4769 ,  G01N2021/479 ,  G01N2021/513 ,  G01N2201/064

Abstract: System and method for detecting and counting bacteria suspended in a biological fluid by means of light scattering measurements is provided. In accordance with the method of the invention the level of signal to noise of the measured intensities of light scattered by a sample of the biological fluid is significantly enhanced for forwardly scattered light within a range of scattering angles which are smaller compared to a predefined maximal scattering angle. The system of the invention includes a cuvette adapted to contain a sample of the biological fluid whose sidewalls and windows are suitably constructed and arranged to significantly reduce the level of reflected light obscuring the scattering patterns measured within the range of scattering angles considered.

Abstract translation: 提供了通过光散射测量来检测和计数悬浮在生物流体中的细菌的系统和方法。 根据本发明的方法，在与预定的最大散射相比较小的散射角范围内的向前散射光显着增强了由生物流体样本散射的光的测量强度的信噪比水平 角度。 本发明的系统包括适于容纳生物流体的样本的比色皿，其侧壁和窗口被适当地构造和布置，以显着降低反射光的水平，掩盖了在所考虑的散射角度范围内测量的散射图案。

公开(公告)号：US07339673B2

公开(公告)日：2008-03-04

申请号：US11158634

申请日：2005-06-22

Applicant: Juan F. Roman

Inventor： Juan F. Roman

IPC: G01J3/50

CPC classification number: G01N21/4785 ,  G01N21/253 ,  G01N21/474 ,  G01N21/78 ,  G01N21/8483 ,  G01N2201/0221 ,  G01N2201/0222 ,  G01N2201/064

Abstract: A miniature readhead for a photometric diagnostic instrument includes a housing of hand-held form factor, configured for receiving reagent sample media therein. The sample media has a plurality of test areas configured to react with, and change color, according to an amount of an analyte in a sample. The holder is sized and shaped for forming an indexed fit with the sample media and includes an array of light sources coupled to the housing, each of the light sources configured to emit light onto a respective one of the test areas. An array of chambers respectively containing an array of light detectors, is configured to enable each of the light detectors to receive diffuse, non-specular reflections of the light from the test areas, while substantially preventing the light detectors from receiving specular reflections of the light.

Abstract translation: 用于光度测量诊断仪器的微型读取头包括手持式外壳的外壳，用于在其中接收试剂样品介质。 样品介质具有多个测试区域，其被配置为根据样品中分析物的量反应并改变颜色。 保持器的尺寸和形状用于与样品介质形成索引配合，并且包括耦合到壳体的光源阵列，每个光源被配置为将光发射到相应的一个测试区域上。 分别包含光检测器阵列的室的阵列被配置为使得每个光检测器能够接收来自测试区域的光的漫反射，非镜面反射，同时基本上防止光检测器接收光的镜面反射 。

公开(公告)号：US07326930B2

公开(公告)日：2008-02-05

申请号：US11033822

申请日：2005-01-13

Applicant: David Alexander Crawely

Inventor： David Alexander Crawely

IPC: G01J5/02

CPC classification number: G01J3/4338 ,  G01J3/0224 ,  G01N21/3581 ,  G01N21/453 ,  G01N2021/1772 ,  G01N2021/1785 ,  G01N2021/3595 ,  G01N2201/064

Abstract: This invention relates to apparatus and methods for sensing terahertz radiation, in particular over an area, and to terahertz radiation imaging systems.A terahertz radiation sensor, the sensor comprising an optical beam input to receive an optical probe beam, a detector to modulate said probe beam responsive to terahertz radiation, and a photosensitive detector to provide an output responsive to said probe beam modulation. The sensor being configured to provide a first optical path between said optical beam input and said electro-optic detector and to provide a second optical path between said electro-optic detector and said photosensitive detector, and wherein said sensor further comprises a polarizer, said polarizer being located in both said first and said second optical paths. We further describe imaging systems for use with such a probe.

Abstract translation: 本发明涉及用于感测太赫兹辐射的装置和方法，特别是涉及一个区域以及太赫兹辐射成像系统。 一种太赫兹辐射传感器，该传感器包括用于接收光学探测光束的光束输入，响应于太赫兹辐射来调制所述探测光束的检测器，以及响应于所述探测光束调制的光敏检测器以提供输出。 所述传感器被配置为在所述光束输入和所述电光检测器之间提供第一光路，并且在所述电光检测器和所述光敏检测器之间提供第二光路，并且其中所述传感器还包括偏振器，所述偏振器 位于所述第一和第二光路两者中。 我们进一步描述与这种探针一起使用的成像系统。

公开(公告)号：US20070063150A1

公开(公告)日：2007-03-22

申请号：US11227195

申请日：2005-09-16

Applicant: Nizar Mullani

Inventor： Nizar Mullani

IPC: G01J1/58 ,  A61B6/00

CPC classification number: G01N21/8806 ,  A61B5/0059 ,  G01N21/8803 ,  G01N2201/061 ,  G01N2201/064

Abstract: Transillumination uses light to image tissues and organs, specifically the veins within the tissue. Strong ambient light hinders the imaging of veins and often, transillumination must be done in a dark or dim room. To enhance the capabilities of a transilluminator, a light shield is placed over the viewing area of the transilluminator so that turning off or dimming of ambient light is not necessary. For pediatric care, a frustroconical adapter attached to the bottom of the transilluminator. The adapter reduces the size of the viewing area.

Abstract translation: 透照使用光来对组织和器官进行成像，特别是组织内的静脉。 强烈的环境光阻碍了静脉成像，而且经常需要在黑暗或昏暗的房间进行透照。 为了增强透照器的功能，将遮光板放置在透照器的观察区域上，以便不需要关闭或调暗环境光。 对于儿科护理，连接在透照器底部的截头锥形适配器。 适配器减小了观看区域的大小。

公开(公告)号：US07173704B2

公开(公告)日：2007-02-06

申请号：US10785411

申请日：2004-02-25

Applicant: Kazunori Yamauchi

Inventor： Kazunori Yamauchi

IPC: G01N21/00

CPC classification number: G01N30/90 ,  G01N21/474 ,  G01N21/78 ,  G01N21/8483 ,  G01N2201/064 ,  G01N2201/0813

Abstract: A measuring device for immunochromatography test piece comprising an irradiation optical system for irradiating measurement light onto an immunochromatography test piece, and a detection optical system for detecting reflected light from the immunochromatography test piece under irradiation with the measurement light. The irradiation optical system comprises a semiconductor light emitting element, a beam shaping member, a lens, a first baffle portion, a second baffle portion, and a third baffle portion. The beam shaping member shapes light from the semiconductor light emitting element, into a beam of a beam section extending in a direction substantially parallel to a colored line formed on the immunochromatography test piece. The lens focuses the beam from the beam shaping member on the immunochromatography test piece. The first baffle portion removes stray light, which is disposed between the semiconductor light emitting element and the beam shaping member. The second baffle portion removes stray light, which is disposed between the beam shaping member and the lens. The third baffle portion removes stray light, which is disposed between the lens and the immunochromatography test piece.

Abstract translation: 一种用于免疫层析试片的测量装置，包括用于将测量光照射到免疫层析试片上的照射光学系统，以及用于在用测量光照射下检测来自免疫层析试片的反射光的检测光学系统。 照射光学系统包括半导体发光元件，光束整形元件，透镜，第一挡板部分，第二挡板部分和第三挡板部分。 光束成形构件将来自半导体发光元件的光成形为沿与免疫层析试片上形成的彩色线基本平行的方向延伸的光束部分的光束。 透镜将来自光束成形构件的光束聚焦在免疫层析试片上。 第一挡板部分去除杂散光，其设置在半导体发光元件和光束成形构件之间。 第二挡板部分去除杂散光，其设置在光束成形构件和透镜之间。 第三挡板部分去除杂散光，其设置在透镜和免疫层析试片之间。

公开(公告)号：US20050237531A1

公开(公告)日：2005-10-27

申请号：US11158634

申请日：2005-06-22

Applicant: Juan Roman

Inventor： Juan Roman

IPC: G01N21/27 ,  G01N21/47 ,  G01N21/86 ,  G06K9/00

CPC classification number: G01N21/4785 ,  G01N21/253 ,  G01N21/474 ,  G01N21/78 ,  G01N21/8483 ,  G01N2201/0221 ,  G01N2201/0222 ,  G01N2201/064

Abstract: A miniature readhead for a photometric diagnostic instrument includes a housing of hand-held form factor, configured for receiving reagent sample media therein. The sample media has a plurality of test areas configured to react with, and change color, according to an amount of an analyte in a sample. The holder is sized and shaped for forming an indexed fit with the sample media and includes an array of light sources coupled to the housing, each of the light sources configured to emit light onto a respective one of the test areas. An array of chambers respectively containing an array of light detectors, is configured to enable each of the light detectors to receive diffuse, non-specular reflections of the light from the test areas, while substantially preventing the light detectors from receiving specular reflections of the light.

Abstract translation: 用于光度测量诊断仪器的微型读取头包括手持式外壳的外壳，用于在其中接收试剂样品介质。 样品介质具有多个测试区域，其被配置为根据样品中分析物的量反应并改变颜色。 保持器的尺寸和形状用于与样品介质形成索引配合，并且包括耦合到壳体的光源阵列，每个光源被配置为将光发射到相应的一个测试区域上。 分别包含光检测器阵列的室的阵列被配置为使得每个光检测器能够接收来自测试区域的光的漫反射，非镜面反射，同时基本上防止光检测器接收光的镜面反射 。

公开(公告)号：US06833919B2

公开(公告)日：2004-12-21

申请号：US10269646

申请日：2002-10-11

Applicant: Jeremy R. Kenseth ,  Ho-Ming Pang ,  Roy F. Strasburg

Inventor： Jeremy R. Kenseth ,  Ho-Ming Pang ,  Roy F. Strasburg

IPC: G01N2100

CPC classification number: G01N27/44721 ,  G01N27/44782 ,  G01N2021/0346 ,  G01N2201/064

Abstract: A multiplexed, absorbance-based electrophoresis system for analyzing multiple samples simultaneously without use of a mask or slit comprising a light source, a planar array of capillary tubes and a detector positioned off-axis with the light source and positioned on-axis with and parallel to the planar array of capillary tubes. Other embodiments include vacuum use attached to the capillary tubes to increase the speed of detection.

公开(公告)号：US06734961B2

公开(公告)日：2004-05-11

申请号：US10068683

申请日：2002-02-06

Applicant: Yuri Gerner ,  Carl W. Sims ,  Thomas J. Thielen

Inventor： Yuri Gerner ,  Carl W. Sims ,  Thomas J. Thielen

IPC: G01N110

CPC classification number: G01N21/05 ,  G01N21/0317 ,  G01N2021/0346 ,  G01N2201/064

Abstract: A flow cell for transporting fluid in a radiant energy field includes a cell structure having a tube extending therethrough including a radiant energy blocking portion integral therewith. In a particular embodiment, the cell structure includes one or more end caps having a protrusion extending therefrom, wherein the protrusion may be inserted into the tube to create a fluid seal, the end caps including open channels for transporting fluid and radiant energy therethrough, and the tube in the cell structure includes an efficient radiant energy transmission lining that is spaced from the end cap protrusions, thereby forming a gap volume in the flow cell open channel, which gap volume may be calibrated such that radiant energy losses may be standardized in respective flow cells transporting fluids having various indexes of refraction.

Abstract translation: 用于在辐射能场中传输流体的流动池包括具有延伸穿过其中的管的电池结构，其包括与其成一体的辐射能阻挡部。 在特定实施例中，电池结构包括一个或多个具有从其延伸的突起的端盖，其中突出部可以插入管中以产生流体密封，端盖包括用于输送流体和辐射能的开口通道，以及 电池结构中的管包括与端盖突起间隔开的有效的辐射能传输衬里，从而在流动池开放通道中形成间隙体积，该间隙体积可以被校准，使得辐射能量损失可以在相应的 输送具有各种折射率的流体的流动池。

公开(公告)号：US5402241A

公开(公告)日：1995-03-28

申请号：US775872

申请日：1991-10-15

Applicant: Anthony C. Jeannotte ,  Arthur Colvin

Inventor： Anthony C. Jeannotte ,  Arthur Colvin

IPC: G01N21/05 ,  G01N21/83 ,  G01N21/85 ,  G01N21/00 ,  G01N1/10

CPC classification number: G01N21/8507 ,  G01N21/83 ,  G01N2021/054 ,  G01N2021/1744 ,  G01N2201/064 ,  G01N2201/0642 ,  G01N2201/08 ,  G01N2201/084

Abstract: Radiant energy is transmitted to a probe element including an interior conical reflecting surface and a fluid sample chamber. Portions of the light which have been transmitted, partially attenuated, or scattered by a fluid sample in the sample chamber are directed by at least a portion of the interior conical reflecting surface to means for collecting the transmitted, partially attenuated, or scattered light. A stilling valve incorporated into the probe element enables elimination of entrained gas bubbles from the chamber.

Abstract translation: 辐射能量传递到包括内部锥形反射表面和流体样品室的探针元件。 通过样品室中的流体样品透射，部分衰减或散射的光的部分由内部锥形反射表面的至少一部分引导到用于收集透射的，部分衰减的或散射的光的装置。 结合到探针元件中的静止阀能够消除来自腔室的夹带的气泡。