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    ANALYTE SENSORS EMPLOYING MULTIPLE ENZYMES AND METHODS ASSOCIATED THEREWITH
    4.
    发明公开
    ANALYTE SENSORS EMPLOYING MULTIPLE ENZYMES AND METHODS ASSOCIATED THEREWITH 审中-公开

    公开(公告)号：US20240350047A1

    公开(公告)日：2024-10-24

    申请号：US18596447

    申请日：2024-03-05

    申请人： Abbott Diabetes Care Inc.

    发明人： Stephen OJA ,  Tianmei OUYANG ,  Hyun CHO ,  Benjamin J. FELDMAN ,  Namvar KIAIE

    IPC分类号： A61B5/1486 ,  A61B5/145 ,  C12Q1/00

    CPC分类号： A61B5/14865 ,  A61B5/14532 ,  C12Q1/002 ,  C12Q1/005 ,  G01N2333/9029 ,  G01N2333/904 ,  G01N2333/908

    摘要： Multiple enzymes may be present in the active area(s) of an electrochemical sensor to facilitate analysis of one or more analytes. The multiple enzymes may function independently to detect several analytes or in concert to detect a single analyte. One sensor configuration includes a first active area and a second active area, where the first active area has an oxidation-reduction potential that is sufficiently separated from the oxidation-reduction potential of the second active area to allow independent signal production. Some sensor configurations may have an active area overcoated with a multi-component membrane containing two or more different membrane polymers. Sensor configurations having multiple enzymes capable of interacting in concert include those in which a first enzyme converts an analyte into a first product and a second enzyme converts the first product into a second product, thereby generating a signal at a working electrode that is proportional to the analyte concentration.

    ANALYTE MONITORING DEVICE AND METHODS OF USE
    6.
    发明公开
    ANALYTE MONITORING DEVICE AND METHODS OF USE 审中-公开

    公开(公告)号：US20240298935A1

    公开(公告)日：2024-09-12

    申请号：US18668458

    申请日：2024-05-20

    申请人： ABBOTT DIABETES CARE INC.

    发明人： Thomas A. Peyser ,  Adam Heller

    IPC分类号： A61B5/145 ,  A61B5/00 ,  A61B5/1473 ,  A61B5/1486

    CPC分类号： A61B5/14532 ,  A61B5/0002 ,  A61B5/0031 ,  A61B5/14546 ,  A61B5/1473 ,  A61B5/14865 ,  A61B5/4839 ,  A61B5/742 ,  A61B5/7445

    摘要： An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor has, for example, a substrate, a recessed channel formed in the substrate, and conductive material disposed in the recessed channel to form a working electrode. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte. The analyte monitor may also be part of a drug delivery system to alter the level of the analyte based on the data obtained using the sensor.