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    MULTI-CHIP MODULE AND METHOD
    2.
    发明公开
    MULTI-CHIP MODULE AND METHOD 审中-公开

    公开(公告)号：US20230145821A1

    公开(公告)日：2023-05-11

    申请号：US18051604

    申请日：2022-11-01

    申请人： Technische Universitat Dresden

    发明人： Niels Neumann ,  Sujay Ashok Charania ,  Dirk Plettemeier ,  Nektarios Koukourakis ,  Stefan Rothe ,  Jurgen Czarske

    IPC分类号： G02B6/12 ,  H04B1/04

    CPC分类号： G02B6/12 ,  H04B1/0483 ,  G02B2006/1209

    摘要： In a multi-chip module and method, the multi-chip module includes a carrier; a multimode optical waveguide formed on and/or in the carrier; a first and second chip disposed on the carrier and coupled to the multimode optical waveguide; wherein the first chip is configured to transmit light beams into the multimode optical waveguide; the multimode optical waveguide is configured to generate mixed light beams that are an at least partial superposition of the light beams; the second chip is configured to receive the mixed light beams from the multimode optical waveguide; and the second chip is configured to store a representation of the received mixed light beams as a transmission signature and/or as a cryptographic key in a memory associated with the second chip, and/or compare the representation of the received mixed light beams with a target representation stored in the memory associated with the second chip.

    ELECTRONIC COMPONENT AND METHOD OF OPERATING AN ELECTRONIC COMPONENT
    3.
    发明申请
    ELECTRONIC COMPONENT AND METHOD OF OPERATING AN ELECTRONIC COMPONENT 有权

    公开(公告)号：US20220320264A1

    公开(公告)日：2022-10-06

    申请号：US17753106

    申请日：2020-10-01

    申请人： Technische Universitat Dresden

    发明人： Hans Kleemann ,  Matteo Cucchi ,  Prof. Dr. Karl Leo ,  Veronika Scholz ,  Hsin Tseng ,  Alexander Lee

    IPC分类号： H01L49/02

    摘要： Described herein is an electronic component that may include a substrate, wherein the substrate may include at least two electrodes, wherein the at least two electrodes are each spaced apart from each other on and/or within the substrate. When the electronic component is in a first operating state, an electrolytic material may be disposed at least in a spatial region between the at least two electrodes, wherein the electrolytic material comprises at least one polymerizable material. When the electronic device is in a second operating state, at least one electrical connection may be made between the at least two electrodes, wherein the at least one electrical connection comprises an electrically conductive polymer. The electrically conductive polymer may comprise one or more fiber structures, wherein the one or more fiber structures are in physical contact with the at least two electrodes.

    Device and method for training a model
    4.
    发明授权
    Device and method for training a model 有权

    公开(公告)号：US11451268B2

    公开(公告)日：2022-09-20

    申请号：US17092818

    申请日：2020-11-09

    申请人： Technische Universitat Dresden

    发明人： Mohammed Radi ,  Emil Matus ,  Gerhard Fettweis

    IPC分类号： H04B7/0413 ,  G06K9/62 ,  G06N3/02 ,  H04L27/26

    摘要： A device and a method for training a model are disclosed, wherein the method of training the model includes: first classifying a plurality of data packets using the model, wherein a first class is assigned to each data packet of a plurality of data packets, wherein the first class is associated with a receiver of a plurality of receivers; second classifying the plurality of data packets, wherein a second class is assigned to each data packet of the plurality of data packets, wherein the second class is associated with a receiver of the plurality of receivers; and training the model using the plurality of first classes and the plurality of second classes assigned to the plurality of data packets.

    HEAT EXCHANGER AND COOLING METHOD
    5.
    发明申请
    HEAT EXCHANGER AND COOLING METHOD 有权

    公开(公告)号：US20220221227A1

    公开(公告)日：2022-07-14

    申请号：US17595215

    申请日：2020-05-20

    申请人： Technische Universitat Dresden

    发明人： Andreas Wagner ,  Yixia Xu ,  Ullrich Hesse

    IPC分类号： F28D1/053 ,  F28F1/00 ,  F28F9/02 ,  F28F13/08 ,  F25B39/02 ,  F25B9/00

    摘要： According to various embodiments of the invention, a heat exchanger can have at least one duct for conveying a coolant, wherein the at least one duct has a first section and a second section, the first section being arranged in the at least one duct upstream relative to the second section, in relation to a flow direction of the coolant, the second section having a cross section area that is larger than a cross section area of the first section, such that a sublimation of the coolant in the second section is made possible.

    RECEIVING DEVICE AND METHOD FOR DETERMINING TRANSMISSION CHARACTERISTICS OF AN OPTICAL WAVEGUIDE
    6.
    发明申请
    RECEIVING DEVICE AND METHOD FOR DETERMINING TRANSMISSION CHARACTERISTICS OF AN OPTICAL WAVEGUIDE 有权

    公开(公告)号：US20220019024A1

    公开(公告)日：2022-01-20

    申请号：US17376320

    申请日：2021-07-15

    申请人： Technische Universitat Dresden

    发明人： Stefan ROTHE ,  Qian ZHANG ,  Nektarios KOUKOURAKIS ,  Robert KUSCHMIERZ ,  Jurgen CZARSKE

    IPC分类号： G02B6/14 ,  H04J14/04 ,  G06N3/02 ,  G01M11/00

    摘要： A receiving apparatus and method for determining transmission characteristics of an optical waveguide in which the receiving apparatus includes a waveguide interface for receiving a mixed light beam having a plurality of modes from a multi-mode optical waveguide and for receiving a blended shifted light beam from the multimode optical waveguide, wherein the mixed light beam has an associated phase for each mode of the plurality of modes, and wherein the mixed shifted light beam has an associated shifted phase for each mode of the plurality of modes; and one or more processors for determining mode information for the intermixed light beam and shifted mode information for the intermixed shifted light beam using a trained neural network and for determining, for each mode of the plurality of modes, the respective associated phase using the intermixed shifted light beam.

    Protein with recombinase activity for site-specific DNA-recombination
    7.
    发明授权
    Protein with recombinase activity for site-specific DNA-recombination 有权

    公开(公告)号：US10253332B2

    公开(公告)日：2019-04-09

    申请号：US15634949

    申请日：2017-06-27

    申请人： Technische Universität Dresden

    发明人： Frank Buchholz ,  Madina Karimova

    IPC分类号： C12N15/87 ,  C12N15/52 ,  C12N15/90 ,  C12N9/12 ,  C12N15/85 ,  C07H21/04 ,  C12N15/55 ,  C12N15/63 ,  C12N15/66

    摘要： The invention relates to the use of a protein with recombinase activity to catalyze a site-specific DNA recombination and a method for producing a site-specific DNA recombination. The invention is applicable alone or in combination with other recombinase systems for genetic manipulation, for example in medical research. The objective of the invention is solved by the use of a protein with recombinase activity to catalyze a site-specific DNA recombination at, preferably at two, recognition sites that are identical or reverse complementary to each other. The invention also includes a method for producing a site-specific DNA recombination comprising the steps of a) providing a cell comprising at least two recognition sites that are identical or reverse complementary to each other; and b) contacting a protein with recombinase activity with the recognition sites, thereby producing the site-specific DNA-recombination.

    Method for producing polarized retinal progenitor cells from pluripotent stem cells and their differentiation into retinal pigment epithelium cells
    9.
    发明授权
    Method for producing polarized retinal progenitor cells from pluripotent stem cells and their differentiation into retinal pigment epithelium cells 有权
    从多能干细胞产生极化视网膜祖细胞及其分化为视网膜色素上皮细胞的方法

    公开(公告)号：US09249390B2

    公开(公告)日：2016-02-02

    申请号：US13096598

    申请日：2011-04-28

    申请人： Yu Zhu ,  Elly Tanaka

    发明人： Yu Zhu ,  Elly Tanaka

    IPC分类号： C12N5/071 ,  C12N15/02 ,  C12N5/079 ,  C12N5/0797 ,  C12N5/0775 ,  C12N5/074 ,  C12N5/0735 ,  C12N5/0793

    CPC分类号： C12N5/0621 ,  C12N5/0606 ,  C12N5/0619 ,  C12N5/062 ,  C12N5/0623 ,  C12N5/0662 ,  C12N5/0696 ,  C12N2501/105 ,  C12N2501/11 ,  C12N2501/115 ,  C12N2501/13 ,  C12N2501/135 ,  C12N2501/15 ,  C12N2501/16 ,  C12N2506/02 ,  C12N2533/52

    摘要： The present invention relates to a method and components for producing polarized retinal progenitor cells (RPC) from pluripotent stem cells in high yield and purity. The polarized retinal progenitor cells are preferably further differentiated with high efficiency and speed into retinal pigment epithelium cells (RPE cells). The cells obtained are particularly suitable for use in cell transplantation or in the generation of transplant tissue and are particularly applicable to screening systems for substances that modulate the function of polarized retinal progenitor cells and/or RPE cells.In the method according to the invention pluripotent stem cells are differentiated into polarized retinal progenitor cells by first culturing pluripotent stem cell colonies in three-dimensional cell culture embedded in a proteinaceous gel comprising at least two proteins selected from the group consisting of Laminin, Collagen IV Entactin and Perlecan and comprising at least two growth factors selected from agonists of the EGF, FGF2, NGF, PDGF, IGF-1 and TGF-beta pathways until polarized neural cysts develop and subsequently dissociating the polarized neural cysts into dispersed polarized retinal progenitor cells.

    摘要翻译： 本发明涉及以高产率和纯度从多能干细胞生产极化视网膜祖细胞（RPC）的方法和组件。 极化视网膜祖细胞优选以高效率和速度进一步分化成视网膜色素上皮细胞（RPE细胞）。 所获得的细胞特别适用于细胞移植或生成移植组织，特别适用于调节极化视网膜祖细胞和/或RPE细胞功能的物质的筛选系统。 在根据本发明的方法中，通过首先在嵌入蛋白质凝胶的三维细胞培养物中培养多能干细胞集落，将多能干细胞分化为极化视网膜祖细胞，其包含至少两种选自层粘连蛋白，胶原蛋白IV Entactin和Perlecan，并且包含选自EGF，FGF2，NGF，PDGF，IGF-1和TGF-β途径的激动剂的至少两种生长因子，直到极化神经囊肿发展并随后将极化神经囊肿解离成分散的极化视网膜祖细胞。