摘要:
A road marker placement system has a frame, a holder mechanically coupled to the frame, a drive system mechanically coupled to the frame, and a rotatable carrier mechanically coupled to the drive system to allow the rotatable carrier to be rotationally driven by the drive system. The rotatable carrier has at least a first pocket formed therein that receives one of the road markers dispensed from an opening of the holder when the rotatable carrier is in a first position. The rotatable carrier is rotated by the drive system from the first position to a second position that is facing the road surface such that the road marker held in the first pocket is forced at least by gravity and by centrifugal force of the rotating rotatable carrier to be ejected from the first pocket onto an adhesive material located on the road surface.
摘要:
The invention provides a molecular marker set that can be used for prognosis of colorectal cancer in a colorectal cancer patient. The invention also provides methods and computer systems for evaluating prognosis of colorectal cancer in a colorectal cancer patient based on the molecular marker set. The invention also provides methods and computer systems for determining chemotherapy for a colorectal cancer patient and for enrolling patients in clinical trials.
摘要:
Protein ubiquitylation, an essential post-translational modification, regulates almost every cellular process including protein degradation, protein trafficking, signal transduction, and DNA damage response in eukaryotic cells. The diverse functions of ubiquitylation are thought to be mediated by distinct chain topologies resulting from eight different ubiquitin linkages, chain lengths, and complexities. Currently, ubiquitin linkages are generally thought to be a critical determinant of ubiquitin signaling. However, ubiquitin chain lengths, another key element of ubiquitin signaling, have not been well documented especially in vivo situation during past three decades from the discovery of ubiquitin. The reason of this was simply because no method has been available for determination of ubiquitin chain length in endogenous ubiquitylated substrates. In the present invention, a practical technique for determining the actual length of substrate-attached polyubiquitin chains from biological samples is established. Using the method, the mean length of substrate-attached polyubiquitin chains was determined and the robustness of ubiquitin chain length regulation in cells is investigated. The following is a summary of findings in this invention: 1. A method for determining ubiquitin chain length was developed and this method was named ‘ubiquitin protection from trypsinization’ (Ub-ProT). 2. Using Ub-ProT, it was determined that the mean length of substrate-attached ubiquitin chains is in the dimer to decamer range. 3. By quantitative proteomics, it was found that the mean lengths of five major types of ubiquitin chains can be divided into two groups. 4. Proteasome-inhibition did not alter the mean length of substrate-attached polyubiquitin chains, indicating that cells have a robust system for regulating ubiquitin chain length.
摘要:
One or more embodiments include paper, methods of making paper, compositions, and the like, are provided. In various exemplary embodiments described herein, a paper material may be formed by treating a cellulosic fiber or an aqueous pulp slurry with a treatment composition comprising an anionic polyacrylamide resin and an aldehyde-functionalized polymer resin.
摘要:
Disclosed are various embodiments for a resource allocation application. Usage data for application program interfaces is aggregated over time. Limits for an allocation of resources for each of the application program interfaces are calculated as a function of the usage data. Limits are recalculated as new application program interfaces are added.
摘要:
A miniaturized ultra-wideband multifunction antenna comprising a conducting ground plane at the base, a plurality of concentric feed cables, one or more omnidirectional one-dimensional (1-D) normal-mode and two-dimensional (2-D) surface-mode traveling-wave (TW) radiators, frequency-selective internal and external couplers, and a unidirectional radiator on top, stacked and cascaded one on top of the other. Configured as a single structure, its unidirectional radiator and plurality of omnidirectional TW radiators can cover, respectively, most satellite and terrestrial communications, with unidirectional and omnidirectional radiation patterns, respectively, needed on various platforms. This new class of multifunction antenna is ultra-wideband, miniaturized and low-cost, thus attractive for applications on automobiles and other small platforms. As a multifunction antenna, a continuous bandwidth up to 1000:1 or more is reachable for terrestrial communications and a continuous bandwidth of 10:1 or more is feasible for satellite communications.
摘要:
Systems and methods are disclosed for automated computer-based notification systems. A representative method, among others that are disclosed herein, can be broadly summarized by the following steps: permitting a first one or more data transfers with a first personal communications device (PCD) for scheduling an order relating to arrival or departure of a mobile thing (MT) at a stop location and to pickup or delivery of a good or service at the stop location; during the first one or more data transfers, requesting and permitting input or selection of quantity information relating to the good and/or service; causing initiation of a second one or more data transfers with the first PCD or a second PCD designated during the first one or more data transfers, prior to completion of the pickup or delivery of the good or service at the stop location; during the second one or more data transfers, permitting a change to the quantity information of the good or service associated with the order that was established during the first one or more data transfers; and permitting the MT to arrive at or depart from the stop location to permit pickup or delivery of the good or service in accordance with the changed quantity information established during the second one or more data transfers. A representative system, among others, can be a computer system that has been programmed to perform the foregoing steps.
摘要:
Systems, methods, and apparatus are disclosed for monitoring appliances at a site, such as a household, business office, etc. The appliances can include, for example but not limited to, an electric oven, dishwasher, refrigerator, laundry washer, freezer, pool controller, light bulb, microwave oven, computer, television, telephone, etc. In many of the embodiments, the appliance has a computer based architecture or a controller that enables communication of data concerning the electronic appliance. In some embodiments the appliance is an apparatus with a radio frequency identification (RFID) tag or other passive device that can be interrogated for information concerning the appliance.
摘要:
Disclosed are various embodiments for a roller cover that can be installed in a conveyor system. The roller cover includes a plate that is configured to be positioned over a roller in the conveyor system. The plate is configured to restrict a movement of an item that is transported by the conveyor system. A first fin and a second fin extend from the plate. The first fin and the second fin attach the roller cover to the conveyor system.