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19 条记录 (耗时 0.016 秒)

    Identification of tissue for debridement
    2.
    发明授权
    Identification of tissue for debridement 有权
    识别清创组织

    公开(公告)号：US08221989B2

    公开(公告)日：2012-07-17

    申请号：US13231251

    申请日：2011-09-13

    申请人： Amy McNulty ,  Kristine Kiesweller ,  Todd Fruchterman

    发明人： Amy McNulty ,  Kristine Kiesweller ,  Todd Fruchterman

    IPC分类号： G01N33/53

    CPC分类号： A61K49/0006 ,  G01N33/52 ,  G01N33/56966 ,  G01N2510/00

    摘要： Provided are methods of determining whether a cell in a tissue site is viable or nonviable. Also provided are methods of debriding tissue from a tissue site. Further provided are kits comprising a compound that distinguishes between viable and nonviable cells and instructions for using the compound on a tissue site. Additionally, the use of a compound that distinguishes between viable and nonviable cells is provided, where the use is to determine whether a cell in a tissue site is viable or nonviable. Also provided is a use of a compound that distinguishes between viable and nonviable cells, where the use is for the manufacture of the above-described kit.

    摘要翻译： 提供了确定组织部位中的细胞是否存活或不可行的方法。 还提供了从组织部位去除组织的方法。 还提供了包含鉴别存活细胞和不可维持细胞的化合物的试剂盒和在组织部位上使用化合物的说明书。 另外，提供区分可行细胞和不可行细胞的化合物的用途，其中用途是确定组织部位中的细胞是否存活或不可行。 还提供了区分可行细胞和不可维持细胞的化合物的用途，其中用于制造上述试剂盒。

    METHOD FOR THE DETECTION AND NEUTRALIZATION OF BACTERIA
    6.
    发明申请
    METHOD FOR THE DETECTION AND NEUTRALIZATION OF BACTERIA 审中-公开
    细菌检测和中和方法

    公开(公告)号：US20070292397A1

    公开(公告)日：2007-12-20

    申请号：US11764604

    申请日：2007-06-18

    申请人： Amy McNulty ,  Kristine Kieswetter ,  Daniel Wadsworth

    发明人： Amy McNulty ,  Kristine Kieswetter ,  Daniel Wadsworth

    IPC分类号： A61K35/76 ,  C12Q1/70 ,  G01N33/554

    CPC分类号： G01N33/56911 ,  A61K35/76 ,  Y02A50/402 ,  Y02A50/475 ,  Y02A50/481

    摘要： The present invention relates to the identification of bacteria present at the site of infection and the treatment of the infection using bacteriophage. In certain embodiments, the present invention provides methods and compositions for treating bacterial infections by identifying at least one bacteria species in the infection based on its interaction with bacteria-specific aptamers, selecting one or more bacteriophage that infect the identified bacteria species, and administering an effective amount of the bacteriophage to the subject to treat the infection.

    摘要翻译： 本发明涉及鉴定存在于感染部位的细菌和使用噬菌体治疗感染。 在某些实施方案中，本发明提供了通过基于其与细菌特异性适体的相互作用鉴定感染中的至少一种细菌种类，选择一种或多种感染鉴定的细菌种的噬菌体，以及施用 有效量的噬菌体对受试者进行感染治疗。

    DEVICES AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF WOUNDS USING BIOMARKERS
    7.
    发明申请
    DEVICES AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF WOUNDS USING BIOMARKERS 审中-公开
    使用生物标志物诊断和治疗伤口的装置和方法

    公开(公告)号：US20120129186A1

    公开(公告)日：2012-05-24

    申请号：US13303921

    申请日：2011-11-23

    申请人： Sandra Garcia ,  Amy McNulty ,  Kristine Villarreal

    发明人： Sandra Garcia ,  Amy McNulty ,  Kristine Villarreal

    IPC分类号： G01N33/566 ,  C40B40/10 ,  G01N33/573 ,  C40B40/04

    CPC分类号： G01N33/6872 ,  G01N33/5091 ,  G01N2333/503 ,  G01N2333/908 ,  G01N2333/966

    摘要： The present invention provides for devices and methods for determining the healing phase of a wound. In some aspects, the present invention provides a wound diagnosis device comprising a surface and at least one agent that is specific to a desired biomarker. In another aspect, the present invention provides a method of determining the phase of wound healing. In still other aspects, the present invention provides methods of determining the phase of wound healing using the disclosed devices.

    摘要翻译： 本发明提供了用于确定伤口愈合阶段的装置和方法。 在一些方面，本发明提供了一种伤口诊断装置，其包括表面和至少一种特定于所需生物标志物的药剂。 另一方面，本发明提供了确定伤口愈合期的方法。 在另外的方面，本发明提供使用所公开的装置确定伤口愈合的相位的方法。

    IDENTIFICATION OF TISSUE FOR DEBRIDEMENT
    9.
    发明申请
    IDENTIFICATION OF TISSUE FOR DEBRIDEMENT 有权
    识别组织用于解散

    公开(公告)号：US20090123931A1

    公开(公告)日：2009-05-14

    申请号：US12265566

    申请日：2008-11-05

    申请人： Amy McNulty ,  Kristine Kissweller ,  Todd Fruchieman

    发明人： Amy McNulty ,  Kristine Kissweller ,  Todd Fruchieman

    IPC分类号： G01N33/53 ,  C12Q1/68

    CPC分类号： A61K49/0006 ,  G01N33/52 ,  G01N33/56966 ,  G01N2510/00

    摘要： Provided are methods of determining whether a cell in a tissue site is viable or nonviable. Also provided are methods of debriding tissue from a tissue site. Further provided are kits comprising a compound that distinguishes between viable and nonviable cells and instructions for using the compound on a tissue site. Additionally, the use of a compound that distinguishes between viable and nonviable cells is provided, where the use is to determine whether a cell in a tissue site is viable or nonviable. Also provided is a use of a compound that distinguishes between viable and nonviable cells, where the use is for the manufacture of the above-described kit.

    摘要翻译： 提供了确定组织部位中的细胞是否存活或不可行的方法。 还提供了从组织部位去除组织的方法。 还提供了包含鉴别存活细胞和不可维持细胞的化合物的试剂盒和在组织部位上使用化合物的说明书。 另外，提供区分可行细胞和不可行细胞的化合物的用途，其中用途是确定组织部位中的细胞是否存活或不可行。 还提供了区分可行细胞和不可维持细胞的化合物的用途，其中用于制造上述试剂盒。