摘要:
Compounds that bind S100 and inhibit the S100-p53 protein-protein interaction and activate the tumor suppressor activity of p53, and thus which have an antineoplastic effect are disclosed, as well as methods for identifying these compounds, compositions comprising the same, and methods of using the same to treat cancer.
摘要:
An apparatus for processing a Bluetooth signal advantageously mixes down a received RF signal to an IF signal wherein one band-edge of the spectrum of the IF signal may be approximately 0 Hz. In one embodiment, the IF signal may be digitized, decimated and filtered before being processed into a baseband signal. The baseband signal may be processed by a cordic (COordinate Rotation DIgital Computer) processor to transform the baseband signal from rectangular to polar coordinates. A phase signal from the cordic processor may be used to determine transmitted Bluetooth data symbols. The apparatus may advantageously use less area than traditional Bluetooth receivers.
摘要翻译:用于处理蓝牙信号的装置有利地将所接收的RF信号与IF信号相混合,其中IF信号的频谱的一个带边可以为大约0Hz。 在一个实施例中,IF信号可以在被处理成基带信号之前被数字化,抽取和滤波。 基带信号可以由Cordic(Coordinate Rotation DIgital Computer)处理器处理,以将基带信号从矩形变换为极坐标。 可以使用来自Cordic处理器的相位信号来确定所发送的蓝牙数据符号。 该装置可以有利地使用比传统蓝牙接收机更少的面积。
摘要:
The present invention provides a breakdown resistant transistor structure for amplifying communication signals. This structure includes a first NMOS transistor having a source connected to ground and a first gate for receiving the input radio frequency signal. The first gate is disposed above a first insulator and the first NMOS transistor having a first transconductance and a first breakdown voltage associated therewith. Also included is a second NMOS transistor having a source connected to the drain of the first NMOS transistor, a gate connected to the reference DC voltage, and a drain that provides the output for the amplified radio signal, the load being disposed between the reference DC voltage and the drain of the second NMOS transistor. The second gate is disposed above a second insulator, the second NMOS transistor has a second transconductance and a second breakdown voltage associated therewith, and the second insulator may be thicker than the first insulator. This results in the first transconductance being greater than the second transconductance, and the second breakdown voltage being greater than the first breakdown voltage.
摘要:
The present invention provides a breakdown resistant transistor structure for amplifying communication signals. This structure includes a first NMOS transistor having a source connected to ground and a first gate for receiving the input radio frequency signal. The first gate is disposed above a first insulator and the first NMOS transistor having a first transconductance and a first breakdown voltage associated therewith. Also included is a second NMOS transistor having a source connected to the drain of the first NMOS transistor, a gate connected to the reference DC voltage, and a drain that provides the output for the amplified radio signal, the load being disposed between the reference DC voltage and the drain of the second NMOS transistor. The second gate is disposed above a second insulator, the second NMOS transistor has a second transconductance and a second breakdown voltage associated therewith, and the second insulator may be thicker than the first insulator. This results in the first transconductance being greater than the second transconductance, and the second breakdown voltage being greater than the first breakdown voltage.
摘要:
Redundancies of power amplifiers (PAs) or low noise amplifiers (LNAs) at the front end of an RF device are used to reduce losses that typically occur at a diversity switch. A signal designator can advantageously be used to select designated signals, which are provided to the PAs for transmitting or provided by the LNAs during receiving.
摘要:
A modulation system comprising a signal processing unit and a modulator. The signal processing unit may generate a low frequency modulator signal, a high frequency modulator signal, and a modulator amplitude control signal. The modulator may generate a modulated signal for transmission via a wireless network based, at least in part, on the low frequency modulator signal, the high frequency modulator signal, and the modulator amplitude control signal. The signal processing unit comprises a delay compensation unit for delaying the generation of the high frequency modulator signal and the modulator amplitude control signal based, at least in part, on signal generation and modulation path delays associated with the low frequency modulator signal to substantially align the modulator signals at the output of the modulation system.
摘要:
A modulation system comprising a signal processing unit and a modulator. The signal processing unit may generate a low frequency modulator signal, a high frequency modulator signal, and a modulator amplitude control signal. The modulator may generate a modulated signal for transmission via a wireless network based, at least in part, on the low frequency modulator signal, the high frequency modulator signal, and the modulator amplitude control signal. The signal processing unit comprises a delay compensation unit for delaying the generation of the high frequency modulator signal and the modulator amplitude control signal based, at least in part, on signal generation and modulation path delays associated with the low frequency modulator signal to substantially align the modulator signals at the output of the modulation system.
摘要:
The present invention provides a synthesizer having an efficient lock detect signal generator, an extended range VCO that can operate within any one of a plurality of adjacent characteristic curves defined by a plurality of adjacent regions, and a divide circuit implemented using only a single counter along with a decoder. This allows for a method of operating the synthesizer, methods of establishing or reestablishing a lock condition using the extended range VCO, and a method of designing a plurality of divide circuits which each use the same single counter and each use a different decoder.
摘要:
Provided herein are protein translation inhibitors and pharmaceutical compositions thereof that bind to an RNA Recognition motif in heterogeneous ribonucleoprotein A18 to inhibit binding to mRNA transcripts thereby inhibiting protein synthesis. Also provided is a method for treating a cancer by administering a pharmaceutically acceptable amounts of at least one of the protein translation inhibitors.