摘要:
The present invention relates to a novel monascuspurpurone compound of formula (I): or a pharmaceutically acceptable derivative thereof as described in the specification, the process for preparation of the same, and the composition comprising the same. The uses of a monascuspurpurone compound for promoting adipocyte differentiation, for increasing the activity of PPARγ and/or C/EBPα, for lowering blood glucose, for preventing and/or treating a disease or disorder related to insulin resistance, and for preventing and/or treating metabolic syndrome or its complications are also provided.
摘要:
The present invention provides a novel species of Acrocarpospora gen. that is capable of producing iodinin. The invention also provides a method of preparing iodinin, and uses of iodinin in inducing cytotoxicity and treating cancers.
摘要:
Cholesterol inhibitor produced by Monascus, monacolin k, is a secondary metabolite of polyketides. The invention provides probes specific to monacolin k biosynthesis gene cluster. BAC clones having putative monacolin k gene cluster were screened from BAC (bacterial artificial chromosome) library, and sequencing and annotation were performed on these clones. The results show that 2 polyketide synthase (PKS) genes and 7 regulatory genes related to monacolin k synthesis were obtained. Full-length cDNAs of these genes were then obtained by RT-PCR and cloned to expression vectors for the expression of these genes.
摘要:
Retrotransposons and methods related thereto. The retrotransposon comprises a nucleotide sequence selected from a group consisting of a nucleotide sequence of SEQ ID NO: 1, a nucleotide sequence of SEQ ID NO: 2, a nucleotide sequence of SEQ ID NO: 3, and a nucleotide sequence encoding a polypeptide of an amino acid sequence of SEQ ID NO: 4.
摘要翻译:反转录转座子及其相关方法。 反转录转座子包含选自SEQ ID NO:1的核苷酸序列,SEQ ID NO:2的核苷酸序列,SEQ ID NO:3的核苷酸序列和编码SEQ ID NO:3的多肽的核苷酸序列的核苷酸序列 SEQ ID NO:4的氨基酸序列。
摘要:
Retrotransposons and methods related thereto. The retrotransposon comprises a nucleotide sequence selected from a group consisting of a nucleotide sequence of SEQ ID NO: 1, a nucleotide sequence of SEQ ID NO: 2, a nucleotide sequence of SEQ ID NO: 3, and a nucleotide sequence encoding a polypeptide of an amino acid sequence of SEQ ID NO: 4.
摘要翻译:反转录转座子及其相关方法。 反转录转座子包含选自SEQ ID NO:1的核苷酸序列,SEQ ID NO:2的核苷酸序列,SEQ ID NO:3的核苷酸序列和编码SEQ ID NO:3的多肽的核苷酸序列的核苷酸序列 SEQ ID NO:4的氨基酸序列。
摘要:
The invention relates to a mutant of Monascus purpureus, designated as Monascus purpureus M011, which is useful in the production of yellow pigments with a low amount of citrinin.
摘要:
The invention relates to a method of producing chitin or chitosan by culturing a Rhizopus azygosporus fungus or an Actinomucor taiwanensis fungus and isolating chitosan or chitin from the culture.
摘要:
The present invention relates to novel pyridine alkaloid compounds of formula (I): or a pharmaceutically acceptable derivative thereof as described in the specification, the process for the preparation of the same, and the composition comprising the same. The uses of a pyridine compound for increasing the activity of PPARγ, for the prevention and/or treatment of a disease or disorder related to insulin resistance, and for the prevention and/or treatment of metabolic syndrome or its complication are also provided. The invention also provides extracts of red yeast-fermented products and their uses for prevention and/or treatment of a disease or disorder related to insulin resistance, such as metabolic syndrome.