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    INTEGRATED MICROFLUIDICS FOR HIGHLY PARALLEL SCREENING OF CHEMICAL REACTIONS
    5.
    发明申请
    INTEGRATED MICROFLUIDICS FOR HIGHLY PARALLEL SCREENING OF CHEMICAL REACTIONS 审中-公开
    综合微流化学高效平行筛选化学反应

    公开(公告)号：US20120309648A1

    公开(公告)日：2012-12-06

    申请号：US12667861

    申请日：2008-07-07

    申请人： Hsian-Rong Tseng ,  Jinyi Wang ,  Guodong Sui ,  Kym F. Faull ,  Yanju Wang ,  Wei-Yu Lin

    发明人： Hsian-Rong Tseng ,  Jinyi Wang ,  Guodong Sui ,  Kym F. Faull ,  Yanju Wang ,  Wei-Yu Lin

    IPC分类号： C40B60/12 ,  C40B30/08

    CPC分类号： B01F13/0059 ,  B01F5/102 ,  B01J2219/00315 ,  B01J2219/00317 ,  B01J2219/00353 ,  B01J2219/00389 ,  B01J2219/00479 ,  B01J2219/00702 ,  B01J2219/0072 ,  B01L3/5027 ,  C07C247/10 ,  C07C247/12 ,  C07C247/14 ,  C07C323/59 ,  C07C2601/08 ,  C07C2601/14 ,  C07D211/68 ,  C07D213/42 ,  C07D213/74 ,  C07D215/42 ,  C07D235/14 ,  C07D295/13 ,  C07D295/32 ,  C07D307/52 ,  C07D311/14 ,  C07D317/28 ,  C07D333/20 ,  C40B40/04 ,  C40B50/08 ,  C40B60/12 ,  G01N2035/00544

    摘要： A microfluidic system has a microfluidic mixer and a sample storage component that is in fluid connection with the microfluidic mixer. The microfluidic mixer has a mixing section; a target molecule input section that is in fluid connection with the mixing section, the target molecule input section being suitable to provide a fluid into the mixing section that contains molecules to be targeted by chemical reactions; a first reagent input section that is in fluid connection with the mixing section, the first reagent input section being structured to selectively provide a first reagent selected from a plurality of reagents to test a chemical reaction with the target molecules; a second reagent input section that is in fluid connection with the mixing section, the second reagent input section being structured to selectively provide a second reagent selected from a plurality of reagents to test a chemical reaction with the target molecules and said first reagent; and a neutral fluid input section that is in selectable fluid connection with the sample storage component, the neutral fluid input section being structured to selectively provide a neutral fluid into the sample storage component between successive samples provided to the sample storage component to separate successive samples in a stratified arrangement.

    摘要翻译： 微流体系统具有微流控混合器和与微流体混合器流体连接的样品存储组件。 微流体混合器具有混合部分; 与混合部分流体连接的目标分子输入部分，靶分子输入部分适合于通过化学反应将含有分子的流体提供给混合部分; 与所述混合部分流体连接的第一试剂输入部，所述第一试剂输入部构造成选择性地提供选自多种试剂的第一试剂，以测试与所述靶分子的化学反应; 与所述混合部分流体连接的第二试剂输入部，所述第二试剂输入部构造成选择性地提供选自多种试剂的第二试剂，以测试与所述靶分子和所述第一试剂的化学反应; 以及中性流体输入部分，其与所述样品存储部件可选择性地流体连接，所述中性流体输入部分被构造成在提供给所述样品存储部件的连续样品之间选择性地将中性流体提供到所述样品存储部件中，以将 分层安排。