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公开(公告)号：US20110182861A1
公开(公告)日：2011-07-28
申请号：US13056344
申请日：2009-07-23
Applicant: Isabelle Castiel , Audrey Gueniche
Inventor： Isabelle Castiel , Audrey Gueniche
CPC classification number: A61Q19/008 , A61K8/99 , A61Q19/00 , Y10S514/859 , Y10S514/864
Abstract: The present invention relates to the cosmetic use of an effective amount of at least one probiotic microorganism and/or a fraction thereof and/or a metabolite thereof, as an agent for treating and/or preventing oily skin or skin with an oily tendency and the associated skin disorders.
Abstract translation: 本发明涉及有效量的至少一种益生菌微生物和/或其部分和/或其代谢物作为用于治疗和/或预防油性皮肤或皮肤的药物的油性倾向的化妆品用途， 相关皮肤病。
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2.发明申请COSMETIC USE OF ANNEXIN II-TYPE PROTEINS FOR TREATING DRYNESS OF THE SKIN 审中-公开用于治疗皮肤干燥的新型II型蛋白质的化妆品用途公开(公告)号：US20110098230A1
公开(公告)日：2011-04-28
申请号：US12936320
申请日：2009-04-02
Applicant: Dominique Bernard , Lucie Simonetti , Isabelle Castiel
Inventor： Dominique Bernard , Lucie Simonetti , Isabelle Castiel
CPC classification number: A61Q19/007 , A61K8/64
Abstract: The present invention relates to the use, in particular cosmetic and/or therapeutic use, of annexin II, of polypeptides derived from this protein or of analogues thereof, of a nucleic sequence encoding such a polypeptide or of a modulator of the activity, the stability or the expression of such a polypeptide, in particular for preventing and/or treating the signs of skin dryness.The invention also relates to the use of annexin II, of polypeptides derived from this protein or of analogues thereof, or of a nucleic sequence encoding such a polypeptide, as a marker for evaluating a state of dryness of an epithelium.
Abstract translation: 本发明涉及膜联蛋白II的用途，特别是化妆品和/或治疗用途，其衍生自该蛋白质或其类似物的多肽编码这种多肽或活性调节剂的核酸序列，其稳定性 或这种多肽的表达，特别是用于预防和/或治疗皮肤干燥症状。 本发明还涉及膜联蛋白II来自该蛋白质或其类似物的多肽或编码这种多肽的核酸序列作为评价上皮干燥状态的标记物的用途。
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3.发明申请公开(公告)号：US20100022648A1
公开(公告)日：2010-01-28
申请号：US12518959
申请日：2007-12-14
Applicant: Audrey Gueniche , Isabelle Castiel
Inventor： Audrey Gueniche , Isabelle Castiel
Abstract: The present invention relates to the cosmetic use by the oral route of at least one monounsaturated fatty acid, a salt thereof and/or an ester thereof, preferably petroselinic acid, for improving the quality of the hair and/or the appearance of the hair, in particular for preventing and/or treating the changes of the scalp and/or of the hair that occur with age.
Abstract translation: 本发明涉及至少一种单不饱和脂肪酸，其盐和/或其酯，优选岩芹酸的口服途径的化妆品用途，用于改善头发的质量和/或毛发的外观， 特别是用于预防和/或治疗随着年龄发生的头皮和/或头发的变化。
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4.发明申请Use of a steroidal or non-steroidal EcR receptor ligand in a cosmetic or dermatological preparation for maintaining cutaneous homeostasis 审中-公开用于化妆品或皮肤病学制剂中的甾族或非甾体EcR受体配体用于维持皮肤内稳态公开(公告)号：US20050137176A1
公开(公告)日：2005-06-23
申请号：US11018982
申请日：2004-12-21
Applicant: Corinne Ferraris , Michelle Josserand , Isabelle Castiel
Inventor： Corinne Ferraris , Michelle Josserand , Isabelle Castiel
IPC: A61K8/00 , A61K8/40 , A61K8/42 , A61K8/49 , A61K8/63 , A61K31/15 , A61K31/56 , A61K31/575 , A61K45/00 , A61P17/16 , A61Q19/00 , A61K7/00
Abstract: The present invention relates to the use of at least one EcR receptor ligand in a cosmetic or dermatological preparation for maintaining cutaneous homeostasis. The present invention also relates to a cosmetic treatment process for maintaining cutaneous homeostasis, which consists in applying a composition according to the invention.
Abstract translation: 本发明涉及至少一种EcR受体配体在化妆品或皮肤病学制剂中用于维持皮肤内稳态的用途。 本发明还涉及一种用于维持皮肤内稳态的美容处理方法，其包括应用根据本发明的组合物。
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5.发明授权Combination of a microorganism and a phytosphingosine derivative, composition, methods of use 有权微生物与植物鞘氨醇衍生物的组合，组合物，使用方法公开(公告)号：US08709454B2
公开(公告)日：2014-04-29
申请号：US12685697
申请日：2010-01-12
Applicant: David Amar , Bruno Bernard , Dominique Bernard , Isabelle Castiel
Inventor： David Amar , Bruno Bernard , Dominique Bernard , Isabelle Castiel
Abstract: At least one phytosphingosine salicylate derivative and at least one lysate of at least one microorganism of the genus Bifidobacterium. Composition, combination. Use, including cosmetic use for reinforcing the repair and regeneration capacity of an epithelium, especially an epidermis, in particular an aged epidermis.
Abstract translation: 至少一种植物精氨酸水杨酸衍生物和至少一种双歧杆菌属微生物的至少一种裂解物。 组合，组合。 使用，包括化妆品用于增强上皮，特别是表皮，特别是老化表皮的修复和再生能力。
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Patent Agency Ranking
公开(公告)号：US20110091439A1
公开(公告)日：2011-04-21
申请号：US12809428
申请日：2008-12-18
Applicant: Dominique Bernard , Lucie Simonetti , Isabelle Castiel
Inventor： Dominique Bernard , Lucie Simonetti , Isabelle Castiel
Abstract: A method for preventing and/or treating the signs of skin aging comprises administering as an agent into an individual in need thereof an effective amount of acid ceramidase, polypeptides derived from this protein or analogues thereof, a nucleic sequence encoding such a polypeptide, or an agent for modulating the expression or the biological or biochemical activity of such a polypeptide. A methods for characterizing a state of an epithelium comprises determining a content of acid ceramidase, polypeptides derived from this protein or analogues thereof, or a nucleic sequence encoding such a polypeptide in an epidermis sample.
Abstract translation: 用于预防和/或治疗皮肤老化症状的方法包括将有效量的酸性神经酰胺酶，衍生自该蛋白质或其类似物的多肽，编码这种多肽的核酸序列，或 用于调节这种多肽的表达或生物或生物化学活性的试剂。 用于表征上皮状态的方法包括确定酸性神经酰胺酶的含量，源自该蛋白质的多肽或其类似物，或在表皮样品中编码这种多肽的核酸序列。
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公开(公告)号：US20100311666A1
公开(公告)日：2010-12-09
申请号：US12515198
申请日：2007-11-16
Applicant: Mark Donovan , Dominique Bernard , Isabelle Castiel , Veronique Chaussade
Inventor： Mark Donovan , Dominique Bernard , Isabelle Castiel , Veronique Chaussade
IPC: A61K38/02 , A61K31/7088 , A61P17/00 , A61P17/06 , A61P17/10 , A61P17/04 , A61P17/08 , A61P29/00 , A61Q19/08 , A61Q19/00 , G01N33/53 , G01N33/573 , C12Q1/68 , C12N5/02 , C12Q1/02
CPC classification number: G01N33/6881 , A61K8/606 , A61K8/66 , A61K38/465 , A61Q19/007 , A61Q19/08 , C12N5/0629 , C12N2501/70 , C12Q1/6883 , C12Q2600/158 , C12Y301/2601 , G01N33/5082 , G01N33/6893 , G01N2333/922 , G01N2500/00 , G01N2800/20
Abstract: The present invention relates to the use, in cosmetics and in therapeutics, of at least one antimicrobial protein belonging to the ribonuclease family, ribonuclease 7, or of polypeptides derived from said protein, notably as a marker for evaluating the condition of the epidermis. It further relates to the use of at least one polypeptide according to the invention, of at least one nucleic acid sequence coding for a polypeptide according to the invention, or of at least one agent that modulates the expression or the activity, notably biological, of said polypeptide or of its interaction with an element of the extracellular matrix, for the preparation of compositions intended for the prevention and/or treatment of skin disorders.
Abstract translation: 本发明涉及在化妆品和治疗学中至少一种属于核糖核酸酶家族的抗微生物蛋白质，核糖核酸酶7或衍生自所述蛋白质的多肽，特别是用作评估表皮条件的标记物。 本发明进一步涉及至少一种根据本发明的多肽的至少一种编码本发明多肽的核酸序列或至少一种调节表达或活性，特别是生物学活性的试剂 所述多肽或其与细胞外基质的元件的相互作用，用于制备旨在预防和/或治疗皮肤病症的组合物。
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8.发明申请COMBINATION OF A MICROORGANISM AND A PHYTOSPHINGOSINE DERIVATIVE, COMPOSITION, METHODS OF USE 有权微生物与植酸蛋白衍生物的组合，组成，使用方法公开(公告)号：US20100203094A1
公开(公告)日：2010-08-12
申请号：US12685697
申请日：2010-01-12
Applicant: David AMAR , Bruno Bernard , Dominique Bernard , Isabelle Castiel
Inventor： David AMAR , Bruno Bernard , Dominique Bernard , Isabelle Castiel
Abstract: At least one phytosphingosine salicylate derivative and at least one lysate of at least one microorganism of the genus Bifidobacterium. Composition, combination. Use, including cosmetic use for reinforcing the repair and regeneration capacity of an epithelium, especially an epidermis, in particular an aged epidermis.
Abstract translation: 至少一种植物精氨酸水杨酸衍生物和至少一种双歧杆菌属微生物的至少一种裂解物。 组合，组合。 使用，包括化妆品用于增强上皮，特别是表皮，特别是老化表皮的修复和再生能力。
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9.发明申请USE OF A COMBINATION OF HESPERIDIN AND OF A MICROORGANISM FOR INFLUENCING THE BARRIER FUNCTION OF THE SKIN 审中-公开使用合成黑皮素和微生物来影响皮肤的障碍功能公开(公告)号：US20090068161A1
公开(公告)日：2009-03-12
申请号：US12204437
申请日：2008-09-04
Applicant: Audrey GUENICHE , Isabelle CASTIEL
Inventor： Audrey GUENICHE , Isabelle CASTIEL
IPC: A61K35/74 , A61K35/66 , A61K31/7028 , A61Q17/00 , A61K8/99 , A61K36/062
CPC classification number: A61Q19/08 , A23L33/105 , A23L33/135 , A23V2002/00 , A23Y2220/63 , A61K8/31 , A61K8/602 , A61K8/99 , A61K9/0014 , A61K9/0095 , A61K9/4858 , A61K31/7048 , A61K35/747 , A61K36/062 , A61K45/06 , A61Q19/007 , Y02A50/473 , A61K2300/00 , A23V2250/21164 , A23V2200/318 , A23V2250/206 , A23V2200/3204 , A23V2250/708 , A23V2200/302
Abstract: The cosmetic use of at least an effective amount of hesperidin or of one of its derivatives in combination with at least an effective amount of at least one microorganism, in particular probiotic microorganism, or one of its fractions as agent for preventing a reduction in and/or for reinforcing the barrier function of the skin.
Abstract translation: 至少有效量的橙皮苷或其衍生物与至少有效量的至少一种微生物，特别是益生微生物或其部分之一的化妆品用途，作为用于防止和/ 或用于增强皮肤的屏障功能。
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10.发明申请公开(公告)号：US20090068160A1
公开(公告)日：2009-03-12
申请号：US12200417
申请日：2008-08-28
Applicant: Isabelle CASTIEL , Lionel BRETON , Audrey GUENICHE
Inventor： Isabelle CASTIEL , Lionel BRETON , Audrey GUENICHE
CPC classification number: A61Q19/005 , A61K8/99
Abstract: Cosmetic use of an effective amount of at least one lysate of at least one microorganism of the genus Bifidobacterium species and/or a fraction thereof, for preventing and/or treating a skin disorder in the case of sensitive skin.
Abstract translation: 化妆品使用有效量的至少一种双歧杆菌属物种和/或其部分的至少一种微生物的裂解物，用于在敏感皮肤的情况下预防和/或治疗皮肤病症。
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