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    Optimised layout for wind turbine rotor blades
    1.
    发明授权
    Optimised layout for wind turbine rotor blades 有权
    风力发电机转子叶片优化布局

    公开(公告)号：US08678770B2

    公开(公告)日：2014-03-25

    申请号：US12594205

    申请日：2008-04-01

    申请人： Peder Bay Enevoldsen ,  Søren Hjort ,  Jesper Laursen

    发明人： Peder Bay Enevoldsen ,  Søren Hjort ,  Jesper Laursen

    IPC分类号： F03D1/06

    CPC分类号： F03D1/0633 ,  F05B2240/30 ,  F05B2250/70 ,  Y02E10/721

    摘要： A wind turbine rotor blade defined by a tip point, a shoulder, a maximum chord interval which is defined as the radial interval over which the blade chord is no less that 95% of the shoulder chord and which extends over at least 15% of the entire blade length, and an outer blade interval extending from the maximum chord interval to the tip point, wherein the outer blade interval has a concave hyperbolic chord distribution from the maximum chord interval towards the tip point. Further a method for optimizing the chord distribution of a wind turbine blade layout is provided, wherein the chord distribution is optimized by optimizing the chord distribution in the maximum chord interval by maximizing the ratio of the annual energy production to the loads acting on the blade and in the outer blade interval with respect to the annual energy production alone.

    摘要翻译： 由尖端，肩部，最大弦间隔限定的风力涡轮机转子叶片，其最大弦间隔被定义为叶片弦不小于肩弦的95％并且延伸至至少15％ 整个刀片长度和从最大弦间隔延伸到尖端点的外刀片间隔，其中外刀片间隔具有从最大弦间隔朝向尖端点的凹双曲线和弦分布。 还提供了一种用于优化风力涡轮机叶片布置的弦分布的方法，其中通过使年能量产生与作用在叶片上的载荷的比例最大化来优化最大弦间隔中的弦分布来优化弦分布;以及 在相对于年度能源生产的外叶间隔中。

    Methods for Flow Cytometry Analyses of Un-Lysed Cells from Biological Fluids
    3.
    发明申请
    Methods for Flow Cytometry Analyses of Un-Lysed Cells from Biological Fluids 审中-公开
    用于生物流体中未裂解细胞的流式细胞术分析方法

    公开(公告)号：US20090105963A1

    公开(公告)日：2009-04-23

    申请号：US12300342

    申请日：2007-05-11

    申请人： Jesper Laursen ,  Ian Storie

    发明人： Jesper Laursen ,  Ian Storie

    IPC分类号： G06F19/00

    CPC分类号： G01N33/56972 ,  G01N15/1475 ,  G01N33/5094

    摘要： A method for analyzing a pathological deviation of at least one white blood cell population from a normal level in an un-lysed blood sample, comprising the steps of counting, with a flow cytometer, a number, n1, of white blood cells expressing a first marker; a number, n2, of white blood cells expressing a second marker, and a number, n3, of white blood cells expressing a third marker but not the first marker; and comparing the sum (n1+n2+n3) with a reference value. The sum (n1+n2+n3) may represent the number of lymphocytes. The first, second and third markers may be chosen from the group consisting of CD56, CD3 and CD19.

    摘要翻译： 一种用于分析未裂解血样中至少一种白细胞群与正常水平的病理学偏差的方法，包括以下步骤：用流式细胞仪计数表达第一 标记 表达第二标记的白细胞数目n2，表达第三标记而不是第一标记的白细胞数n3; 并将和（n1 + n2 + n3）与参考值进行比较。 总和（n1 + n2 + n3）可以表示淋巴细胞数。 第一，第二和第三标记可以选自CD56，CD3和CD19。

    High-Speed Quantification of Antigen Specific T-Cells in Whole Blood by Flow Cytometry
    4.
    发明申请
    High-Speed Quantification of Antigen Specific T-Cells in Whole Blood by Flow Cytometry 审中-公开
    通过流式细胞术高效定量全血中抗原特异性T细胞

    公开(公告)号：US20090061478A1

    公开(公告)日：2009-03-05

    申请号：US12161579

    申请日：2007-01-30

    申请人： Lene Have Poulsen ,  Kivin Jacobsen ,  Ian Storie ,  Jesper Laursen

    发明人： Lene Have Poulsen ,  Kivin Jacobsen ,  Ian Storie ,  Jesper Laursen

    IPC分类号： C12Q1/06

    CPC分类号： G01N33/505 ,  G01N2015/0065 ,  G01N2015/1486

    摘要： The present invention discloses novel methods and compositions for identifying particular cell types in whole blood samples and defining either the concentration or ‘absolute count’ of these cells per unit volume of the sample. More specifically, the invention relates to methods for quantifying the antigen-specific T cells or defining the relative percentage of said cells in un-lysed whole blood. Further, the invention relates to kits for the preparation of whole blood samples for high-speed quantification of particular cell types, e.g. antigen specific T-cells, in said whole blood samples by flow cytometry.

    摘要翻译： 本发明公开了用于鉴定全血样品中特定细胞类型的新颖方法和组合物，并定义了每单位体积样品中这些细胞的浓度或“绝对计数”。 更具体地，本发明涉及定量抗原特异性T细胞或限定未裂解全血中所述细胞的相对百分比的方法。 此外，本发明涉及用于制备用于高速定量特定细胞类型的全血样品的试剂盒，例如， 抗原特异性T细胞，通过流式细胞仪检测所有全血样品。

    Cell counting
    5.
    发明授权
    Cell counting 有权
    细胞计数

    公开(公告)号：US08541227B2

    公开(公告)日：2013-09-24

    申请号：US11884247

    申请日：2006-02-06

    申请人： Nanna K Christensen ,  Jesper Laursen ,  Lars Winther

    发明人： Nanna K Christensen ,  Jesper Laursen ,  Lars Winther

    IPC分类号： C12M1/34 ,  G01N33/543 ,  G01N31/22

    CPC分类号： G01N15/1459 ,  G01N33/543 ,  G01N33/54366 ,  G01N33/54393 ,  G01N2015/1486 ,  Y10T436/101666

    摘要： The inventions relates to compositions and method for determining the absolute counts of cells per unit volume of a sample. Such a method comprises: (a) providing a container containing (i) a predetermined quantity of microparticles; and (ii) a cell-binding agent; in which the microparticles are disposed in or on a matrix which adheres to at least one wall of the container such that substantially all the microparticles are thereby attached to the container; (b) adding a known volume of sample to the container; (c) determining the ratio of microparticles to cells by counting microparticles and cells in a volume of the sample; and (d) determining the absolute count of cells by multiplying the number of cells per microparticle by the concentration of microparticles in the sample. Preferably, the matrix retains substantially all the microparticles in or on the container during routine handling, including inversion, of the container, in the absence of mechanical retaining means such as a retainer grid in the container.

    摘要翻译： 本发明涉及用于确定样品每单位体积的细胞的绝对计数的组合物和方法。 这种方法包括：（a）提供容器，其容纳（i）预定量的微粒; 和（ii）细胞结合剂; 其中微粒设置在基质中或基体上，该基质附着在容器的至少一个壁上，使得基本上所有的微粒从而附着到容器上; （b）向容器中加入已知体积的样品; （c）通过计数样品体积中的微粒和细胞来确定微粒与细胞的比例; 和（d）通过将每个微粒的细胞数乘以样品中微粒的浓度来确定细胞的绝对计数。 优选地，在没有诸如容器中的保持架网格的机械保持装置的情况下，基体在基本上将容器内的所有微粒保持在容器的常规处理（包括反转）中。

    Optimised layout for wind turbine rotor blades
    8.
    发明申请
    Optimised layout for wind turbine rotor blades 有权
    风力发电机转子叶片优化布局

    公开(公告)号：US20100196166A1

    公开(公告)日：2010-08-05

    申请号：US12594205

    申请日：2008-04-01

    申请人： Peder Bay Enevoldsen ,  Søren Hjort ,  Jesper Laursen

    发明人： Peder Bay Enevoldsen ,  Søren Hjort ,  Jesper Laursen

    IPC分类号： F03D11/00

    CPC分类号： F03D1/0633 ,  F05B2240/30 ,  F05B2250/70 ,  Y02E10/721

    摘要： A wind turbine rotor blade defined by a tip point, a shoulder, a maximum chord interval which is defined as the radial interval over which the blade chord is no less that 95% of the shoulder chord and which extends over at least 15% of the entire blade length, and an outer blade interval extending from the maximum chord interval to the tip point, wherein the outer blade interval has a concave hyperbolic chord distribution from the maximum chord interval towards the tip point. Further a method for optimizing the chord distribution of a wind turbine blade layout is provided, wherein the chord distribution is optimized by optimizing the chord distribution in the maximum chord interval by maximizing the ratio of the annual energy production to the loads acting on the blade and in the outer blade interval with respect to the annual energy production alone.

    摘要翻译： 由尖端，肩部，最大弦间隔限定的风力涡轮机转子叶片，其最大弦间隔被定义为叶片弦不小于肩弦的95％并且延伸至至少15％ 整个刀片长度和从最大弦间隔延伸到尖端点的外刀片间隔，其中外刀片间隔具有从最大弦间隔朝向尖端点的凹双曲线和弦分布。 还提供了一种用于优化风力涡轮机叶片布置的弦分布的方法，其中通过使年能量产生与作用在叶片上的载荷的比例最大化来优化最大弦间隔中的弦分布来优化弦分布;以及 在相对于年度能源生产的外叶间隔中。

    Cell Counting
    10.
    发明申请
    Cell Counting 有权
    细胞计数

    公开(公告)号：US20080194508A1

    公开(公告)日：2008-08-14

    申请号：US11884247

    申请日：2006-02-06

    申请人： Nanna K. Christensen ,  Jesper Laursen ,  Lars Winther

    发明人： Nanna K. Christensen ,  Jesper Laursen ,  Lars Winther

    IPC分类号： A61K31/70 ,  C12Q1/06 ,  G01N33/569 ,  A61P43/00 ,  A61K31/59 ,  C12M1/00

    CPC分类号： G01N15/1459 ,  G01N33/543 ,  G01N33/54366 ,  G01N33/54393 ,  G01N2015/1486 ,  Y10T436/101666

    摘要： The inventions relates to compositions and method for determining the absolute counts of cells per unit volume of a sample. Such a method comprises: (a) providing a container containing: (i) a predetermined quantity of microparticles; and (ii) a cell-binding agent; in which the microparticles are disposed in or on a matrix which adheres to at least one wall of the container such that substantially all the microparticles are thereby attached to the container; (b) adding a known volume of sample to the container; (c) determining the ratio of microparticles to cells by counting microparticles and cells in a volume of the sample; and (d) determining the absolute count of cells by multiplying the number of cells per microparticle by the concentration of microparticles in the sample. Preferably, the matrix retains substantially all the microparticles in or on the container during routine handling, including inversion, of the container, in the absence of mechanical retaining means such as a retainer grid in the container.

    摘要翻译： 本发明涉及用于确定样品每单位体积的细胞的绝对计数的组合物和方法。 这种方法包括：（a）提供容器，其包含：（i）预定量的微粒; 和（ii）细胞结合剂; 其中微粒设置在基质中或基体上，该基质附着在容器的至少一个壁上，使得基本上所有的微粒从而附着到容器上; （b）向容器中加入已知体积的样品; （c）通过计数样品体积中的微粒和细胞来确定微粒与细胞的比例; 和（d）通过将每个微粒的细胞数乘以样品中微粒的浓度来确定细胞的绝对计数。 优选地，在没有诸如容器中的保持架网格的机械保持装置的情况下，基体在基本上将容器内的所有微粒保持在容器的常规处理（包括反转）中。