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    Electrostatic sampler and method
    3.
    发明授权
    Electrostatic sampler and method 有权
    静电采样器和方法

    公开(公告)号：US07428848B2

    公开(公告)日：2008-09-30

    申请号：US11199754

    申请日：2005-08-09

    Applicant: Kapil Pant ,  Guiren Wang ,  Jianjun Feng ,  Shankar Sundaram

    Inventor： Kapil Pant ,  Guiren Wang ,  Jianjun Feng ,  Shankar Sundaram

    IPC: G01N1/24

    CPC classification number: G01N1/2202

    Abstract: The present invention is an electrostatic collector for low cost, high throughput, high efficiency sampling and concentration of bioaerosols. The device is small enough to be portable and can be contained within or placed on the wall of a typical office or hospital building. The collector comprises one or more collector modules, each having an ionizing electrode, a conical outer electrode, a wet collection electrode, and a liquid collection system. Airflow through a collector module may be partially blocked to enhance the collection of smaller particles and the collection electrode may comprise multiple, programmable electrodes to focus particle deposition onto a smaller area. Particles are collected into a small volume of liquid to facilitate subsequent analysis by an attached analyzer or at a remote site.

    Abstract translation: 本发明是用于低成本，高产量，高效率采样和浓缩生物气溶胶的静电收集器。 该装置足够小以便于携带并且可以被包含在典型的办公室或医院建筑物的墙壁内或放置在典型的办公室或医院建筑物的墙壁上。 收集器包括一个或多个收集器模块，每个收集器模块具有电离电极，圆锥形外部电极，湿式收集电极和液体收集系统。 通过收集器模块的气流可能被部分阻塞以增强较小颗粒的收集，并且收集电极可以包括多个可编程电极，以将颗粒沉积物聚焦到更小的区域上。 将颗粒收集到少量液体中，以便随后通过附着的分析仪或远程位置进行分析。

    Electrostatic sampler and method
    5.
    发明申请
    Electrostatic sampler and method 有权
    静电采样器和方法

    公开(公告)号：US20070034025A1

    公开(公告)日：2007-02-15

    申请号：US11199754

    申请日：2005-08-09

    Applicant: Kapil Pant ,  Guiren Wang ,  Jianjun Feng ,  Shankar Sundaram

    Inventor： Kapil Pant ,  Guiren Wang ,  Jianjun Feng ,  Shankar Sundaram

    IPC: G01N1/24

    CPC classification number: G01N1/2202

    Abstract: The present invention is an electrostatic collector for low cost, high throughput, high efficiency sampling and concentration of bioaerosols. The device is small enough to be portable and can be contained within or placed on the wall of a typical office or hospital building. The collector comprises one or more collector modules, each having an ionizing electrode, a conical outer electrode, a wet collection electrode, and a liquid collection system. Airflow through a collector module may be partially blocked to enhance the collection of smaller particles and the collection electrode may comprise multiple, programmable electrodes to focus particle deposition onto a smaller area. Particles are collected into a small volume of liquid to facilitate subsequent analysis by an attached analyzer or at a remote site.

    Abstract translation: 本发明是用于低成本，高产量，高效率采样和浓缩生物气溶胶的静电收集器。 该装置足够小以便于携带并且可以被包含在典型的办公室或医院建筑物的墙壁内或放置在典型的办公室或医院建筑物的墙壁上。 收集器包括一个或多个收集器模块，每个收集器模块具有电离电极，圆锥形外部电极，湿式收集电极和液体收集系统。 通过收集器模块的气流可能被部分阻塞以增强较小颗粒的收集，并且收集电极可以包括多个可编程电极，以将颗粒沉积物聚焦到更小的区域上。 将颗粒收集到少量液体中，以便随后通过附着的分析仪或远程位置进行分析。

    Method for designing extrusion dies
    6.
    发明授权
    Method for designing extrusion dies 有权
    挤出模具设计方法

    公开(公告)号：US08682620B2

    公开(公告)日：2014-03-25

    申请号：US12949851

    申请日：2010-11-19

    Applicant: Jianjun Feng ,  Eric Paul Granberg ,  Maxwell Joseph Wingert

    Inventor： Jianjun Feng ,  Eric Paul Granberg ,  Maxwell Joseph Wingert

    IPC: G06F17/50 ,  G06F7/66

    CPC classification number: B29C47/0859 ,  B29C33/3835 ,  B29C47/0002 ,  B29C47/0009 ,  B29C47/0854 ,  B29C47/14 ,  B29C47/92 ,  B29C2947/92514 ,  B29C2947/926 ,  B29C2947/92666 ,  B29C2947/92904

    Abstract: A method of designing a die cavity that may include performing a flow analysis using characteristics of a predetermined die cavity, density and rheological properties of a material, and a flow rate of the material to calculate the pressure distribution exerted on the die cavity and cross-sectional flow profile. The method further includes a structural analysis using the calculated pressure distribution and structural characteristics of the die cavity to calculate a deformed die cavity. The flow analysis is repeated using the characteristics of the deformed die cavity to calculate a pressure distribution exerted on the die cavity and cross-sectional flow profile. The outcome is compared to determine if the pressure distributions and/or cross-sectional flow profiles converge. These steps are iteratively repeated until convergence of the pressure and/or cross-sectional flow profile is observed. The variation of the cross-sectional flow profile is analyzed to determine if it is below a predetermined tolerance.

    Abstract translation: 设计模腔的方法，其可以包括使用预定模腔的特性，材料的密度和流变特性以及材料的流速来执行流动分析，以计算施加在模腔上的压力分布， 截面流动剖面图。 该方法还包括使用计算的压模分布和模腔的结构特征来计算变形模腔的结构分析。 使用变形模腔的特征重复流动分析，以计算施加在模腔上的压力分布和横截面流动分布。 比较结果以确定压力分布和/或横截面流动剖面是否收敛。 迭代地重复这些步骤，直到观察到压力和/或横截面流动分布的收敛。 分析横截面流动剖面的变化以确定其是否低于预定的公差。

    Thrombectomy microcatheter
    8.
    发明授权
    Thrombectomy microcatheter 有权
    血栓切除微导管

    公开(公告)号：US07842006B2

    公开(公告)日：2010-11-30

    申请号：US11561303

    申请日：2006-11-17

    Applicant: Guiren Wang ,  Shivshankar Sundaram ,  Kapil Pant ,  Jianjun Feng ,  Peter Storm

    Inventor： Guiren Wang ,  Shivshankar Sundaram ,  Kapil Pant ,  Jianjun Feng ,  Peter Storm

    IPC: A61B17/22

    CPC classification number: A61B17/2202 ,  A61B2017/00778 ,  A61B2017/22001 ,  A61B2017/22021

    Abstract: The present invention is an ultrasonic thrombectomy catheter that produces physical forces (shear rates) strong enough to emulsify obstructions such as thrombi and emboli without causing damage to arterial walls. This is accomplished by properly arranging piezoelectric transducers within a catheter and a tubular catheter head separated by a gap to generate acoustic streaming that simultaneously emulsifies the obstruction and sweeps resulting debris into a catheter lumen for removal. The open gap may be formed by supporting struts that connect the catheter to the catheter head. The design of the catheter tip allows the fabrication of catheters capable of removing partial or complete blockages from arteries and other vessels having diameters as small as 2 mm.

    Abstract translation: 本发明是一种超声波血栓切除术导管，其产生足够强的物理力​​（剪切速率）以乳化阻塞物如血栓和栓塞，而不会对动脉壁造成损伤。 这是通过将压电换能器适当地布置在导管内的管状导管头和由间隙分开的管状导管头来实现的，以产生声流，其同时乳化阻塞物并将所得碎片扫入导管腔以便移除。 开放间隙可以通过将导管连接到导管头上的支柱支撑而形成。 导管尖端的设计允许制造能够从直径小至2mm的动脉和其他容器中去除部分或完全阻塞的导管。

    Self-cleaning and mixing microfluidic elements
    9.
    发明申请
    Self-cleaning and mixing microfluidic elements 有权
    自清洁和混合微流体元件

    公开(公告)号：US20070209940A1

    公开(公告)日：2007-09-13

    申请号：US11516358

    申请日：2006-09-06

    Applicant: Sivaramakrishnan Krishnamoorthy ,  Jianjun Feng

    Inventor： Sivaramakrishnan Krishnamoorthy ,  Jianjun Feng

    IPC: B01D57/02 ,  B03C5/00

    CPC classification number: B08B7/0064 ,  B01F13/0079 ,  B01F13/0081 ,  B01L3/5027 ,  B01L99/00 ,  B01L2300/1833 ,  B01L2400/0415 ,  B01L2400/0442 ,  B01L2400/0493 ,  B08B9/00 ,  F04B19/006 ,  F04B19/24 ,  Y10S366/04 ,  Y10T137/0329 ,  Y10T137/034 ,  Y10T137/0391

    Abstract: Apparatus and methods are disclosed for mixing and self-cleaning elements in microfluidic systems based on electrothermally induced fluid flow. The apparatus and methods provide for the control of fluid flow in and between components in a microfluidic system to cause the removal of unwanted liquids and particulates or mixing of liquids. The geometry and position of electrodes is adjusted to generate a temperature gradient in the liquid, thereby causing a non-uniform distribution of dielectric properties within the liquid. The dielectric non-uniformity produces a body force and flow in the solution, which is controlled by element and electrode geometries, electrode placement, and the frequency and waveform of the applied voltage.

    Abstract translation: 公开了用于基于电热诱导流体流动的微流体系统中的混合和自清洁元件的装置和方法。 该装置和方法提供了在微流体系统中的组件之间和之间的流体流动的控制，以便除去不期望的液体和微粒或混合液体。 调节电极的几何形状和位置，以在液体中产生温度梯度，从而导致液体内介电性质的不均匀分布。 电介质非均匀性在溶液中产生体力和流动，其由元件和电极几何形状，电极布置以及施加电压的频率和波形控制。

    Methods and systems employing electrothermally induced flow for mixing and cleaning in microsystems
    10.
    发明授权
    Methods and systems employing electrothermally induced flow for mixing and cleaning in microsystems 有权
    在微系统中采用电热诱导流混合和清洗的方法和系统

    公开(公告)号：US07189578B1

    公开(公告)日：2007-03-13

    申请号：US10307907

    申请日：2002-12-02

    Applicant: Jianjun Feng ,  Sivaramakrishnan Krishnamoorthy ,  Vinod Bhagwan Makhijani

    Inventor： Jianjun Feng ,  Sivaramakrishnan Krishnamoorthy ,  Vinod Bhagwan Makhijani

    IPC: G01N1/00 ,  G01N1/10 ,  G01N35/00 ,  H05F3/00 ,  B01D57/02

    CPC classification number: B08B9/00 ,  B01F13/0079 ,  B01F13/0081 ,  B01L3/5027 ,  B01L99/00 ,  B01L2300/1833 ,  B01L2400/0415 ,  B01L2400/0442 ,  B01L2400/0493 ,  B08B7/0064 ,  F04B19/006 ,  F04B19/24 ,  Y10T29/49 ,  Y10T29/49002 ,  Y10T436/11 ,  Y10T436/25 ,  Y10T436/2575

    Abstract: A method and system for controlling flow motion in a channel/cavity in a microfluidic system includes positioning at least one pair of electrodes in and/or proximate to the channel/cavity. A buffer solution is placed in the channel/cavity, the buffer solution having at least one dielectric property that varies in response to changes in temperature of the solution. An AC/DC voltage is applied to the electrodes to generate an electric field in the channel/cavity; the AC voltage having a known magnitude and frequency and the DC voltage having a known magnitude. The magnitude of the AC/DC voltage is adjusted to cause Joule heating of the buffer solution in the channel/cavity. The geometry and position of the electrodes is adjusted to generate a temperature gradient in the buffer solution, thereby causing a non-uniform distribution of the dielectric property within the solution in the channel/cavity. The dielectric non-uniformity produces a body force and flow in the solution. Also, the frequency of the AC voltage is adjusted to generate flow of the buffer solution in the channel/cavity in response to the non-uniform distribution of the dielectric property.

    Abstract translation: 用于控制微流体系统中的通道/空腔中的流动的方法和系统包括将至少一对电极定位在通道/空腔中和/或接近通道/空腔。 将缓冲溶液放置在通道/空腔中，缓冲溶液具有响应于溶液温度变化而变化的至少一种介电特性。 AC / DC电压施加到电极以在通道/空腔中产生电场; AC电压具有已知的幅度和频率，并且DC电压具有已知的幅度。 调整AC / DC电压的大小，使通道/腔中的缓冲溶液焦耳加热。 调节电极的几何形状和位置以在缓冲溶液中产生温度梯度，从而导致溶液中的介电性质在通道/空腔中的不均匀分布。 电介质非均匀性会在溶液中产生体力和流动。 此外，响应于介电性质的不均匀分布，调节AC电压的频率以产生通道/空腔中的缓冲溶液的流动。

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