公开(公告)号：US20130129635A1

公开(公告)日：2013-05-23

申请号：US13699298

申请日：2011-05-24

申请人： Jon Nagy ,  Joyce Wong ,  Adam Luce ,  Ragnhild Whitaker ,  Robin Cleveland ,  Yoonjee Park

发明人： Jon Nagy ,  Joyce Wong ,  Adam Luce ,  Ragnhild Whitaker ,  Robin Cleveland ,  Yoonjee Park

IPC分类号： A61K49/22

CPC分类号： A61K49/223

摘要： The present invention relates to the fabrication and use of microbubbles. In some embodiments, the invention provides for the fabrication and use of polymerized shell lipid microbubbles (PSMs). The microbubbles of the invention can be used, for example, for diagnosis and treatment of a condition.

摘要翻译： 本发明涉及微泡的制造和使用。 在一些实施方案中，本发明提供了聚合壳脂质微泡（PSM）的制备和使用。 本发明的微泡可以用于例如病症的诊断和治疗。

公开(公告)号：US07675252B2

公开(公告)日：2010-03-09

申请号：US11431317

申请日：2006-05-10

申请人： Felix K. Chen ,  Joyce Wong ,  Gary W. Corris ,  Stephen Balkunas ,  Zilu Zhou ,  James G. Haug

发明人： Felix K. Chen ,  Joyce Wong ,  Gary W. Corris ,  Stephen Balkunas ,  Zilu Zhou ,  James G. Haug

IPC分类号： H05H7/00

CPC分类号： H05H11/00

摘要： A betatron structure having a donut-shaped vacuum chamber, wherein the vacuum chamber is made up of two or more pieces bonded together; an injector positioned within the vacuum chamber; and two or more magnets positioned to the outside of the vacuum chamber. A method of manufacturing a betatron structure, including: (a) fabricating two or more pieces; (b) positioning an injector on one of the two or more pieces; and (c) bonding the two or more pieces such that when bonded, the substrates form a hollow donut-shaped chamber.

摘要翻译： 具有环形真空室的贝塔管结构，其中真空室由两个或多个粘结在一起的部件构成; 位于真空室内的喷射器; 以及位于真空室外部的两个或更多个磁体。 一种制造贝塔管结构的方法，包括：（a）制造两个或多个片; （b）将喷射器定位在所述两个或更多个部件之一上; 和（c）粘合两个或更多个片，使得当粘合时，基底形成中空的环形腔室。

公开(公告)号：US20080029564A1

公开(公告)日：2008-02-07

申请号：US11498419

申请日：2006-08-03

申请人： Joyce Wong ,  Hai-I Wong

发明人： Joyce Wong ,  Hai-I Wong

IPC分类号： A45F5/00 ,  A45F3/00 ,  A45F3/14

CPC分类号： A63B47/00 ,  A45F3/02 ,  A45F3/14 ,  A63B47/001

摘要： An athletic ball carrier has a strap assembly that is able to open and close to retain balls. A first set of straps may be interconnected at a connection point. The connection point may be opposed from an intersection area. A transverse strap is secured to the first set of straps. A draw string can be adjustably secured to the first set of straps to “close” the strap assembly to hold balls of varying shapes and sizes.

摘要翻译： 一种运动型球载体具有能够打开和关闭以保持球的带组件。 第一组带可以在连接点处相互连接。 连接点可以与交叉区域相对。 横向带固定到第一组带子上。 拉绳可以可调节地固定到第一组皮带上，以使“绑带”带组件保持不同形状和尺寸的球。

公开(公告)号：US07799278B2

公开(公告)日：2010-09-21

申请号：US10885471

申请日：2004-07-06

申请人： Philippe Salamitou ,  Joyce Wong ,  Bhavani Raghuraman ,  Jagdish Shah ,  Ronald E. G. Van Hal ,  Robert J. Schroeder ,  Patrick Jean René Tabeling

发明人： Philippe Salamitou ,  Joyce Wong ,  Bhavani Raghuraman ,  Jagdish Shah ,  Ronald E. G. Van Hal ,  Robert J. Schroeder ,  Patrick Jean René Tabeling

IPC分类号： G01N21/00

CPC分类号： B01L3/502715 ,  B01L3/502707 ,  B01L3/50273

摘要： A microfluidic system for performing fluid analysis is described having: (a) a submersible housing having a fluid analysis means and a power supply to provide power to said system; and (b) a substrate for receiving a fluid sample, having embedded therein a fluid sample inlet, a reagent inlet, a fluid sample outlet, and a mixing region in fluid communication with the fluid sample inlet, the reagent inlet, and the fluid sample outlet, and wherein the substrate includes a fluid drive means for moving the fluid sample through the substrate, and wherein the substrate interconnects with the housing. At least a portion of the fluid analysis means may be embedded in the substrate.

摘要翻译： 描述了一种用于执行流体分析的微流体系统，其具有：（a）具有流体分析装置的潜水壳体和向所述系统提供动力的电源; （b）用于接收流体样品的基板，其中嵌入有流体样品入口，试剂入口，流体样品出口和与流体样品入口，试剂入口和流体样品流体连通的混合区域 出口，并且其中所述基板包括用于使所述流体样品通过所述基板移动的流体驱动装置，并且其中所述基板与所述壳体相互连接。 流体分析装置的至少一部分可以嵌入衬底中。

公开(公告)号：US20100012586A1

公开(公告)日：2010-01-21

申请号：US12503650

申请日：2009-07-15

申请人： Dan Eugen Angelescu ,  Philippe Salamitou ,  Joyce Wong ,  Bhavani Raghuraman ,  Brian Oliver Clark ,  Christopher Harrison ,  Matthew Sullivan ,  Andreas Hausot ,  Florence le Gallic de Kerizouet

发明人： Dan Eugen Angelescu ,  Philippe Salamitou ,  Joyce Wong ,  Bhavani Raghuraman ,  Brian Oliver Clark ,  Christopher Harrison ,  Matthew Sullivan ,  Andreas Hausot ,  Florence le Gallic de Kerizouet

IPC分类号： B01D61/12

CPC分类号： B01D65/08 ,  B01D61/18 ,  B01D67/0062 ,  B01D2321/2016 ,  B01L3/502753 ,  B01L3/502784 ,  B01L2200/0673 ,  B01L2300/0627 ,  B01L2300/0681 ,  B01L2300/0864 ,  B01L2300/0877 ,  B01L2300/161 ,  B01L2400/0487 ,  E21B43/38 ,  E21B49/081 ,  E21B49/10 ,  G01N1/4005 ,  G01N33/28 ,  G01N2001/4016

摘要： A fluid separation method for performing fluid analysis of an unfiltered fluid. The fluid separation method includes providing a structure with a fluid analyzer and a power supply. Using a substrate for receiving a fluid flow stream of a multiphase mixture through a fluid sample inlet, wherein the substrate interconnects with the structure. Providing a membrane disposed across the fluid sample inlet for separating a fluid of interest from the multiphase mixture, wherein the fluid flow stream of the multiphase mixture has a shear rate that prevents a fouling of the membrane. Finally, the fluid separation method includes the substrate having fabricated channels, such that the fabricated channels are arranged substantially tangent to the fluid stream downstream of the porous membrane.

摘要翻译： 一种用于对未过滤流体进行流体分析的流体分离方法。 流体分离方法包括提供具有流体分析器和电源的结构。 使用基底用于通过流体样品入口接收多相混合物的流体流，其中所述基底与所述结构相互连接。 提供跨过流体样品入口设置的膜，用于将感兴趣的流体与多相混合物分离，其中多相混合物的流体流动流具有防止膜结垢的剪切速率。 最后，流体分离方法包括具有制造通道的基板，使得所制造的通道基本上与多孔膜下游的流体流相切。

公开(公告)号：US20060261759A1

公开(公告)日：2006-11-23

申请号：US11431317

申请日：2006-05-10

申请人： Felix Chen ,  Joyce Wong ,  Gary Corris ,  Stephen Balkunas ,  Zilu Zhou ,  James Haug

发明人： Felix Chen ,  Joyce Wong ,  Gary Corris ,  Stephen Balkunas ,  Zilu Zhou ,  James Haug

IPC分类号： H05H7/00

CPC分类号： H05H11/00

摘要： A betatron structure having a donut-shaped vacuum chamber, wherein the vacuum chamber is made up of two or more pieces bonded together; an injector positioned within the vacuum chamber; and two or more magnets positioned to the outside of the vacuum chamber. A method of manufacturing a betatron structure, including: (a) fabricating two or more pieces; (b) positioning an injector on one of the two or more pieces; and (c) bonding the two or more pieces such that when bonded, the substrates form a hollow donut-shaped chamber.

摘要翻译： 具有环形真空室的贝塔管结构，其中真空室由两个或多个粘结在一起的部件构成; 位于真空室内的喷射器; 以及位于真空室外部的两个或更多个磁体。 一种制造贝塔管结构的方法，包括：（a）制造两个或多个片; （b）将喷射器定位在所述两个或更多个部件之一上; 和（c）粘合两个或更多个片，使得当粘合时，基底形成中空的环形腔室。

公开(公告)号：US20060008913A1

公开(公告)日：2006-01-12

申请号：US10935858

申请日：2004-09-08

申请人： Dan Angelescu ,  Philippe Salamitou ,  Joyce Wong ,  Bhavani Raghuraman ,  Brian Clark

发明人： Dan Angelescu ,  Philippe Salamitou ,  Joyce Wong ,  Bhavani Raghuraman ,  Brian Clark

IPC分类号： G01N33/24 ,  G01N1/18

CPC分类号： B01D67/0062 ,  B01D17/085 ,  B01D19/0031 ,  B01D61/18 ,  B01L3/502753 ,  B01L2200/0673 ,  B01L2300/0681 ,  B01L2300/0864 ,  B01L2300/161 ,  B01L2400/0487 ,  E21B43/38 ,  E21B47/10 ,  E21B49/081 ,  E21B49/10 ,  G01N1/4005 ,  G01N33/28 ,  G01N2001/4016 ,  Y10T436/25375

摘要： The present invention provides methods and apparatus for separating and/or analyzing fluids of interest. According to principles of the present invention, fluid analysis is accomplished with microfluidic devices and may be reported in real-time or near real-time in a subterranean environment. In addition or alternative to oilfield applications, the principles of the present invention contemplate separation in a laboratory or other environment for biological sample separation and analytical chemistry applications. The present invention is capable of separating liquid-liquid mixtures or emulsions in a microfluidic device without fouling.

公开(公告)号：US09230772B2

公开(公告)日：2016-01-05

申请号：US13338702

申请日：2011-12-28

申请人： Zilu Zhou ,  Joyce Wong

发明人： Zilu Zhou ,  Joyce Wong

IPC分类号： H01J27/02 ,  H01J37/08 ,  H05H3/06 ,  H01J1/304 ,  G21G4/02 ,  H01J35/06

CPC分类号： H01J27/02 ,  G21G4/02 ,  H01J1/3044 ,  H01J35/065 ,  H01J37/08 ,  H05H3/06

摘要： Illustrative embodiments of the present invention are directed to devices and methods for ion generation. One such device includes a substrate. The substrate is disposed within a housing that is configured to contain a gas. The substrate includes an interior surface that at least partially defines an interior volume. The substrate also includes a number of channels with walls. Nano-tips are disposed on the walls of the channels.

摘要翻译： 本发明的说明性实施例涉及用于离子产生的装置和方法。 一种这样的装置包括基板。 衬底设置在被配置为容纳气体的壳体内。 衬底包括至少部分地限定内部容积的内表面。 衬底还包括多个具有壁的通道。 纳米尖端设置在通道的壁上。

公开(公告)号：US20130170592A1

公开(公告)日：2013-07-04

申请号：US13338702

申请日：2011-12-28

申请人： ZILU ZHOU ,  JOYCE WONG

发明人： ZILU ZHOU ,  JOYCE WONG

IPC分类号： G21G4/02 ,  H01J27/02

CPC分类号： H01J27/02 ,  G21G4/02 ,  H01J1/3044 ,  H01J35/065 ,  H01J37/08 ,  H05H3/06

摘要： Illustrative embodiments of the present invention are directed to devices and methods for ion generation. One such device includes a substrate. The substrate is disposed within a housing that is configured to contain a gas. The substrate includes an interior surface that at least partially defines an interior volume. The substrate also includes a number of channels with walls. Nano-tips are disposed on the walls of the channels.

摘要翻译： 本发明的说明性实施例涉及用于离子产生的装置和方法。 一种这样的装置包括基板。 衬底设置在被配置为容纳气体的壳体内。 衬底包括至少部分地限定内部容积的内表面。 衬底还包括多个具有壁的通道。 纳米尖端设置在通道的壁上。

公开(公告)号：US20110011157A1

公开(公告)日：2011-01-20

申请号：US12503902

申请日：2009-07-16

申请人： Bertrand Bourlon ,  Joyce Wong ,  Paul B. Guieze

发明人： Bertrand Bourlon ,  Joyce Wong ,  Paul B. Guieze

IPC分类号： G01N30/04 ,  E21B47/08 ,  G03F7/20

CPC分类号： G01N30/6095 ,  B01J20/205 ,  B01J20/282 ,  B01J2220/54 ,  G01N2030/567

摘要： A carbon nanostructured micro-fabricated gas chromatography column which is particularly well-suited to the surface well-site and/or the downhole analysis of natural gas in oilfield or gasfield applications (but which may also be used in non-oilfield or non-gasfield situations) is described. This micro-fabricated column integrates a micro-structured substrate such as a silicon substrate with carbon nanotubes as an active nanostructured material in a micro-channel. Benefits of the present invention include enhanced separation of alkanes and isomers, particularly below hexane (i.e., below C6), as well as the separation of carbon dioxide, hydrogen sulfide, and water and other substances present in natural gas. The chromatography column of the present invention is in one embodiment a part of an entire gas chromatograph system that in its simplest form also comprises an injector and a detector. Preferably the injector, separation column, and detector are all micro-fabricated on a substrate.

摘要翻译： 一种碳纳米微结构微气相色谱柱，特别适用于油田或气田应用中天然气的表面井场和/或井下分析（但也可用于非油田或非气田 情况）。 该微制造柱在微通道中将诸如硅衬底的微结构衬底与作为活性纳米结构材料的碳纳米管集成。 本发明的优点包括增加烷烃和异构体的分离，特别是低于己烷（即低于C6），以及分离天然气中存在的二氧化碳，硫化氢和水等物质。 在一个实施方案中，本发明的色谱柱是整个气相色谱系统的一部分，其最简单的形式还包括注射器和检测器。 优选地，注射器，分离柱和检测器都在基底上微制造。