公开(公告)号：US07632233B2

公开(公告)日：2009-12-15

申请号：US11206168

申请日：2005-08-18

申请人： Yoshiaki Satoh ,  Kazuhiro Tsujita

发明人： Yoshiaki Satoh ,  Kazuhiro Tsujita

IPC分类号： A61B8/14 ,  H01L41/00

CPC分类号： A61B8/12 ,  A61B8/145 ,  A61B8/4461 ,  A61B8/4483 ,  A61B8/4488 ,  G01S15/8922 ,  G01S15/8979

摘要： In an ultrasonic endoscope capable of being inserted into a body of a patient and imaging ultrasonic tomographic images, a frame rate in electronic radial scanning operation is improved. The ultrasonic endoscope includes: an ultrasonic transducer unit including plural ultrasonic transducers, each having a first electrode and a second electrode, for transmitting and receiving ultrasonic waves; a plurality of first interconnections each connected to the first electrodes of predetermined ultrasonic transducers; and a plurality of second interconnections each connected to the second electrodes of ultrasonic transducers having the first electrodes not connected to each other; wherein the ultrasonic transducer unit performs scanning operation by simultaneously transmitting the same number of ultrasonic beams in each of plural angle regions when selectively supplied with drive signals via the plurality of first interconnections and the plurality of second interconnections.

摘要翻译： 在能够插入患者体内的超声波内窥镜和超声波断层图像的成像中，提高了电子放射线扫描操作中的帧速率。 超声波内窥镜包括：超声波换能器单元，包括多个超声波换能器，每个具有第一电极和第二电极，用于发送和接收超声波; 多个第一互连，每个连接到预定的超声换能器的第一电极; 以及多个第二互连，每个第二互连连接到具有彼此不连接的第一电极的超声换能器的第二电极; 其中，当通过所述多个第一互连和所述多个第二互连选择性地提供驱动信号时，所述超声换能器单元通过同时发送多个角度区域中的每一个中的相同数量的超声波束来执行扫描操作。

公开(公告)号：US20090021739A1

公开(公告)日：2009-01-22

申请号：US12175033

申请日：2008-07-17

申请人： Kazuhiro TSUJITA ,  Hiroshi SUNAGAWA ,  Katsuya KIKUCHI ,  Tetsuya KAWANISHI

发明人： Kazuhiro TSUJITA ,  Hiroshi SUNAGAWA ,  Katsuya KIKUCHI ,  Tetsuya KAWANISHI

IPC分类号： G01N21/25

CPC分类号： G01J3/51 ,  A61B1/00163 ,  A61B1/00186 ,  A61B1/043 ,  A61B1/063 ,  A61B1/0638 ,  A61B1/0669 ,  G01J3/36 ,  G01J3/513 ,  H04N5/2256 ,  H04N5/33 ,  H04N9/045 ,  H04N9/07 ,  H04N9/09 ,  H04N2209/043 ,  H04N2209/044 ,  H04N2209/045

摘要： An imaging apparatus includes a light source unit that selectively outputs white light and light in a different wavelength band to an observation target, an imaging unit including an imaging device, and a spectral image formation circuit that generates a spectral image signal for a specified wavelength by an operation using an image signal based on an output from the imaging unit and predetermined matrix data. The imaging unit selectively obtains an image of the observation target for each of first, second and third light components in a visible light region and an image for each of at least fourth and fifth light components in a near-infrared region. Further, the imaging unit includes first spectral devices that make only the first and fourth light components enter first pixels of the imaging device and second spectral devices that make only the second and fifth light components enter second pixels thereof.

摘要翻译： 一种成像设备包括：光源单元，其选择性地将白光和不同波长带的光输出到观察对象;成像单元，包括成像装置;以及光谱图像形成电路，其通过以下方式产生特定波长的光谱图像信号 使用基于来自成像单元的输出的图像信号和预定矩阵数据的操作。 成像单元在近红外区域中选择性地获得可见光区域中的第一，第二和第三光分量中的每一个的观察目标图像和用于至少第四和第五光分量中的每一个的图像。 此外，成像单元包括仅使第一和第四光分量进入成像装置的第一像素的第一光谱装置和仅使第二和第五光分量进入其第二像素的第二光谱装置。

公开(公告)号：US07450242B2

公开(公告)日：2008-11-11

申请号：US11535361

申请日：2006-09-26

申请人： Masahiro Toida ,  Yoshikatsu Morishima ,  Kazuhiro Tsujita ,  Hiroshi Fujita

发明人： Masahiro Toida ,  Yoshikatsu Morishima ,  Kazuhiro Tsujita ,  Hiroshi Fujita

IPC分类号： G01B9/02

CPC分类号： G01B9/02004 ,  A61B5/0066 ,  A61B5/0071 ,  A61B5/0073 ,  A61B5/0084 ,  A61B5/0086 ,  G01B9/02003 ,  G01B9/02014 ,  G01B9/02044 ,  G01B9/02091 ,  G01J3/10 ,  G01N21/4795

摘要： Low coherence light having a central wavelength λc of 1.1 μm and a full width at half maximum spectrum Δλ of 90 nm is emitted. The low coherence light has wavelength properties suited for the light absorbing properties, the diffusion properties, and the dispersion properties of living tissue. A light dividing means divides the low coherence light into a measuring light beam, which is irradiated onto a measurement target via an optical probe, and a reference light beam that propagates toward an optical path length adjusting means. A multiplexing means multiplexes a reflected light beam, which is the measuring light beam reflected at a predetermined depth of the measurement target, and the reference light beam, to form coherent light. A coherent light detecting means detects the optical intensity of the multiplexed coherent light. An image obtaining means performs image processes, and displays an optical tomographic image on a display apparatus.

摘要翻译： 发射具有1.1μm的中心波长lambdac和半峰全宽度的低相干光，发射90nm的Deltalambda。 低相干光具有适合于吸光性能，扩散性能和生物体组织的分散性能的波长特性。 光分割装置将低相干光分成通过光学探针照射到测量对象上的测量光束和朝向光程长度调节装置传播的参考光束。 多路复用装置将作为在测量对象的预定深度处反射的测量光束的反射光和参考光束进行多路复用，以形成相干光。 相干光检测装置检测多路复用相干光的光强度。 图像获取装置执行图像处理，并在显示装置上显示光学断层图像。

公开(公告)号：US20050203405A1

公开(公告)日：2005-09-15

申请号：US11077123

申请日：2005-03-11

申请人： Kazuhiro Tsujita

发明人： Kazuhiro Tsujita

IPC分类号： A61B8/08 ,  A61B8/02 ,  A61B8/06 ,  A61B8/12 ,  G01S7/52

CPC分类号： A61B8/08 ,  G01S7/52036

摘要： Ultrasonic imaging method and apparatus capable of expressing differences of tissues more clearly by focusing attention on the relationship between characteristics of an object and frequency characteristics of received ultrasonic waves. The apparatus includes an ultrasonic transmitting and receiving unit for transmitting and receiving ultrasonic waves to obtain a detection signal; a frequency component calculating unit for calculating plural frequency components from data based on the detection signal; a tissue discrimination computing unit for obtaining characteristics, which change depending on tissues of the object, based on the calculated plural frequency components; a selector unit for selecting at least one of plural frequency bands corresponding to at least one tissue displayed within one screen in accordance with the obtained characteristics; and an image data generating unit for generating image data representing an ultrasonic image based on intensity of the detection signal in the selected frequency band.

摘要翻译： 通过将注意力集中在物体的特性与接收的超声波的频率特性之间的关系上，能够更清楚地表现组织差异的超声成像方法和装置。 该装置包括用于发送和接收超声波以获得检测信号的超声波发射和接收单元; 频率分量计算单元，用于根据检测信号从数据中计算多个频率分量; 组织识别计算单元，用于基于所计算的多个频率分量获得根据对象的组织而改变的特性; 选择器单元，用于根据所获得的特征来选择对应于在一个屏幕内显示的至少一个组织的多个频带中的至少一个; 以及图像数据生成单元，用于基于所选择的频带中的检测信号的强度来生成表示超声波图像的图像数据。

公开(公告)号：US06800057B2

公开(公告)日：2004-10-05

申请号：US10156693

申请日：2002-05-29

申请人： Kazuhiro Tsujita ,  Yukihiko Nakajima

发明人： Kazuhiro Tsujita ,  Yukihiko Nakajima

IPC分类号： A61B1045

CPC分类号： A61B1/00186 ,  A61B1/00009 ,  A61B1/043 ,  A61B1/0638 ,  A61B1/0646 ,  A61B5/0071 ,  A61B5/0084

摘要： An accurate determination of the tissue state of a diseased portion is performed by use of an image obtaining apparatus employing a charge multiplying type solid state image obtaining element. A target subject is irradiated with an illuminating light that contains an excitation light, and the reflected light, which includes a fluorescence image, reflected from the target subject thereupon is detected by a charge multiplying type CCD. At this time, the fluorescent light image is passed through a rotating filter, and is detected as a wide band fluorescent light image and a narrow band fluorescent light image by the charge multiplying type CCD, and obtained as a wide band fluorescence image data and a narrow band fluorescence image data by an image processing unit. A fluorescence diagnostic image is obtained of the wide band fluorescence image data and the narrow band fluorescence image data, and displayed on a monitor.

摘要翻译： 通过使用采用电荷倍增型固态图像获得元件的图像获取装置来执行患病部分的组织状态的精确确定。 用包含激发光的照明光照射目标被摄体，并且通过电荷倍增型CCD检测从目标物体反射的包括荧光图像的反射光。 此时，荧光图像通过旋转滤光器，并通过电荷倍增型CCD被检测为宽带荧光图像和窄带荧光图像，并作为宽带荧光图像数据和 窄带荧光图像数据由图像处理单元。 获得宽带荧光图像数据和窄带荧光图像数据的荧光诊断图像，并显示在监视器上。

公开(公告)号：US07914457B2

公开(公告)日：2011-03-29

申请号：US11244297

申请日：2005-10-06

申请人： Yoshiaki Satou ,  Tomoo Sato ,  Hiroyuki Karasawa ,  Kazuhiro Tsujita

发明人： Yoshiaki Satou ,  Tomoo Sato ,  Hiroyuki Karasawa ,  Kazuhiro Tsujita

IPC分类号： A61B8/14 ,  A61B8/00 ,  G01N9/24

CPC分类号： A61B8/4438 ,  A61B8/12 ,  A61B8/4411 ,  A61B8/4488 ,  B06B1/0633 ,  G10K11/341

摘要： An ultrasonic probe of a radial scan type mountable on an ultrasonic observation apparatus, which inputs and outputs M numbers of signals in parallel, comprises the following: N (N>M) numbers of ultrasonic transducers disposed on an outer periphery of a tip, and grouped into plural sensor element groups activated in sequence, each of which has M numbers of ultrasonic transducers; N numbers of first signal lines respectively connected to the N numbers of ultrasonic transducers for transmitting a drive signal for driving the ultrasonic transducers and an echo signal from within a living organism; M numbers of second signal lines connected to the ultrasonic observation apparatus; and a multiplexer disposed between the first signal lines and the second signal lines, which selectively switches M numbers of the first signal lines for respectively connecting to the second signal lines according to the sensor element group to be activated.

摘要翻译： 可安装在超声波观察装置上的径向扫描型超声波探头，其并联输入和输出M个信号，包括：设置在尖端外周的超声波换能器的N（N> M）个数，以及 被分组成依次激活的多个传感器元件组，每个具有M个超声波换能器; 分别连接到N个超声波换能器的N个第一信号线，用于传输用于驱动超声波换能器的驱动信号和来自活体内的回波信号; 连接到超声波观察装置的M个第二信号线; 以及多路复用器，设置在第一信号线和第二信号线之间，根据要被激活的传感器元件组，选择性地切换M个第一信号线以分别连接到第二信号线。

公开(公告)号：US07179221B2

公开(公告)日：2007-02-20

申请号：US10401027

申请日：2003-03-28

申请人： Kazuhiro Tsujita ,  Yukihiro Nakajima

发明人： Kazuhiro Tsujita ,  Yukihiro Nakajima

IPC分类号： A61B1/04 ,  G06K9/00

CPC分类号： A61B1/04

摘要： A correcting portion of an endoscope subjects a reference image to a magnification correction process so that the distance between a first mark and a second mark within the reference image is substantially equal to the distance between a first mark and a second mark within a comparative image. Next, the corrected reference image is subjected to a rotation correction process so that the orientation of the second mark with respect to the first mark within the reference image is substantially equal to the orientation of the second mark with respect to the first mark image within the comparison image. Further, the corrected reference image is subjected to a brightness distribution correction process so that the brightness distribution thereof becomes equal to that of the comparison image. The display state of the reference image and comparison image are made substantially equal, comparative diagnosis is facilitated, and diagnostic efficiency is improved.

摘要翻译： 内窥镜的校正部分将参考图像进行放大校正处理，使得参考图像内的第一标记和第二标记之间的距离基本上等于比较图像内的第一标记和第二标记之间的距离。 接下来，对经过校正的参考图像进行旋转校正处理，使得第二标记相对于参考图像内的第一标记的取向基本上等于第二标记相对于第一标记图像的取向 比较图。 此外，校正的参考图像经受亮度分布校正处理，使得其亮度分布变得等于比较图像的亮度分布。 使参考图像和比较图像的显示状态基本相等，便于比较诊断，提高了诊断效率。

公开(公告)号：US20060256348A1

公开(公告)日：2006-11-16

申请号：US11389331

申请日：2006-03-27

申请人： Masahiro Toida ,  Kazuhiro Tsujita ,  Hiroshi Fujita

发明人： Masahiro Toida ,  Kazuhiro Tsujita ,  Hiroshi Fujita

IPC分类号： G01B11/02

CPC分类号： A61B5/0084 ,  A61B5/0066 ,  A61B5/0086 ,  A61B5/6852

摘要： A light source unit emits a laser beam, of which the wavelength is swept at a predetermined period. The central wavelength λc of the sweep and the wavelength sweep width Δλ of the laser light beam satisfy the conditions: λc2′/Δλ≦23, λc+(Δλ/2)≦1.2 μm, and λc−(Δλ/2)≧0.98 μm. A light dividing means divides the laser beam into a measuring light beam, which is irradiated onto a measurement target via an optical probe, and a reference light beam that propagates toward an optical path length adjusting means. A multiplexing means multiplexes a reflected light beam, which is the measuring light beam reflected at a predetermined depth of the measurement target, and the reference light beam, to form a coherent light beam. A coherent light beam detecting means detects the intensity of the multiplexed coherent light beam. Image processes are performed, an optical tomographic image is displayed.

摘要翻译： 光源单元发射激光束，其中波长以预定周期扫描。 激光束的扫描的中心波长和波长扫描宽度Deltalambda满足条件：lambdac / Deltalambda <= 23，lambdac +（Deltalambda / 2）<= 1.2 mum， lambdac-（Deltalambda / 2）> = 0.98 mum。 光分割装置将激光束分割成通过光学探针照射到测量对象物上的测量光束和向光路长度调节装置传播的参考光束。 多路复用装置将作为测量对象的预定深度反射的测量光束的反射光和参考光束多路复用，以形成相干光束。 相干光束检测装置检测多路复用相干光束的强度。 执行图像处理，显示光学断层图像。

公开(公告)号：US07126686B2

公开(公告)日：2006-10-24

申请号：US10920412

申请日：2004-08-18

申请人： Kazuhiro Tsujita

发明人： Kazuhiro Tsujita

IPC分类号： G01J3/28 ,  G01J3/18

CPC分类号： G02B26/0808 ,  G01J3/06 ,  G01J3/18 ,  G01J3/28

摘要： A spectral image measurement apparatus comprises: a spectral element array; a spectral element drive section for driving the elements; an inlet-side optical system for guiding a light to the element array; a detection-side optical system for forming an image with a diffracted light output from the element array; and an array sensor for detecting the diffracted light through the detection-side optical system. The element array includes: a substrate; and a plurality of micro-electrically-driven mechanical spectral elements arranged two-dimensionally on the substrate, wherein each of the elements comprises a diffraction grating having a diffraction surface, the diffraction grating being pivotably supported on the substrate; wherein each of the elements generates spectra from a light entering the diffraction surface by applying an electric field to the diffraction grating to tilt the diffraction grating; and wherein each of tilt angles of the diffraction gratings is capable of being set individually.

摘要翻译： 光谱图像测量装置包括：光谱元件阵列; 用于驱动元件的光谱元件驱动部分; 用于将光引导到元件阵列的入口侧光学系统; 用于形成具有从元件阵列输出的衍射光的图像的检测侧光学系统; 以及用于检测通过检测侧光学系统的衍射光的阵列传感器。 元件阵列包括：基板; 以及在基板上二维布置的多个微电驱动机械光谱元件，其中每个元件包括具有衍射面的衍射光栅，衍射光栅可枢转地支撑在基板上; 其中每个元件通过向衍射光栅施加电场以倾斜衍射光栅，从进入衍射表面的光产生光谱; 并且其中每个衍射光栅的倾斜角度能够单独设定。

公开(公告)号：US06556854B1

公开(公告)日：2003-04-29

申请号：US09495758

申请日：2000-02-01

申请人： Tomoo Sato ,  Masahiro Toida ,  Kazuhiro Tsujita

发明人： Tomoo Sato ,  Masahiro Toida ,  Kazuhiro Tsujita

IPC分类号： A61B505

CPC分类号： A61B5/02007 ,  A61B5/0059

摘要： A homodyne interference system splits first and second light beams from a common light source and causes the first and second light beams to impinge upon an irradiating point of an organism at different directions. An optical heterodyne system splits a third beam from the common light source and imparts a frequency shift to the third beam. The outputs of the homodyne and heterodyne systems combine to permit extraction of a beat component of the homodyne system at a high SNR level. The output of the homodyne and heterodyne system are output as an image, which may be timed to a phase timing mechanism to provide an improved output.

摘要翻译： 零差干涉系统分离来自公共光源的第一和第二光束，并且使第一和第二光束在不同方向上撞击生物体的照射点。 光学外差系统将来自公共光源的第三光束分离，并向第三光束施加频移。 零差和外差系统的输出结合起来，允许以高SNR水平提取零差系统的拍子分量。 零差和外差系统的输出作为图像输出，其可以被定时到相位定时机构以提供改进的输出。