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39 条记录 (耗时 0.028 秒)

    Nanoelectronic-enzyme linked immunosorbent assay system and method
    1.
    发明授权
    Nanoelectronic-enzyme linked immunosorbent assay system and method 有权
    纳米电子酶联免疫吸附测定系统及方法

    公开(公告)号：US09188594B2

    公开(公告)日：2015-11-17

    申请号：US12535396

    申请日：2009-08-04

    申请人： Tarek M. Fahmy ,  Eric D. Stern ,  Mark A. Reed ,  Aleksandar Vacic ,  James F. Klemic

    发明人： Tarek M. Fahmy ,  Eric D. Stern ,  Mark A. Reed ,  Aleksandar Vacic ,  James F. Klemic

    IPC分类号： G01N33/543 ,  G01N33/68

    CPC分类号： G01N33/54366 ,  G01N33/54373 ,  G01N33/6863 ,  G01N33/6866 ,  G01N33/6869 ,  G01N2333/54 ,  G01N2333/555 ,  G01N2333/98

    摘要： The present invention relates to a device and method for determining the presence of a specific compound in solution. The device includes a nanosensor having an electrically conducting pathway between at least a first and second contact. The device also includes a first receptor, suitable for binding a specific compound in the solution, attached to the nanosensor, and a second receptor also suitable for binding the specific compound while the specific compound is bound to the first receptor. The second receptor is attached to an enzyme added to the solution. When the solution having the second receptor is added to the device, and a second compound that is a substrate for the enzyme is subsequently added to the solution, a measured difference in an electrical property in the device before and after the application of the second compound is indicative of the presence of the specific compound in the solution.

    摘要翻译： 本发明涉及一种用于测定溶液中特定化合物的存在的装置和方法。 该装置包括在至少第一和第二接触之间具有导电路径的纳米传感器。 该装置还包括适于结合附着于纳米传感器的溶液中的特定化合物的第一受体，以及也适于结合特定化合物而第二受体，而特异性化合物与第一受体结合。 第二受体与添加到溶液中的酶连接。 当将具有第二受体的溶液加入到装置中，并且随后将另外作为酶底物的第二化合物加入到溶液中时，测量第二化合物施用前后装置的电性能差异 表明该溶液中特定化合物的存在。

    Electronic device for pathogen detection
    2.
    发明授权
    Electronic device for pathogen detection 有权
    用于病原体检测的电子装置

    公开(公告)号：US09120105B2

    公开(公告)日：2015-09-01

    申请号：US13664967

    申请日：2012-10-31

    申请人： Monika Weber ,  Mark A. Reed

    发明人： Monika Weber ,  Siu Lung Lo ,  Hazael Fabrizio Montanaro Ochoa ,  Christopher Daniel Yerino ,  Mark A. Reed

    IPC分类号： G01N27/447 ,  B03C5/02 ,  G01N33/487 ,  B03C5/00 ,  B01L3/00 ,  G01N27/414

    CPC分类号： B03C5/024 ,  B01L3/502753 ,  B01L2300/0874 ,  B01L2400/0406 ,  B01L2400/0424 ,  B01L2400/0487 ,  B03C5/005 ,  B03C2201/26 ,  G01N27/4145 ,  G01N33/487

    摘要： An apparatus and method for separating an analyte from a test sample, such as bacteria from blood components, based on their dielectric properties, localizing or condensing the analyte, flushing substantially all remaining waste products from the test sample, and detecting low concentrations of the analyte. Species movement is caused by a module array imparting opposing dielectrophoretic forces. The module array includes a plurality of microfluidic channels with connecting microfluidic waste channels for directing undesired material away from the analyte. An electric field is applied causing a positive dielectrophoretic force to the analyte to capture the analyte. The Clausius-Mossotti factor of the analyte is changed by flushing the analyte with a reference solution, which causes a negative dielectrophoretic force to facilitate release of the analyte. A field effect nanowire or nanoribbon sensor detects the analyte after capture.

    摘要翻译： 基于它们的介电特性，将分析物从测试样品例如细菌分离出来的装置和方法，定位或冷凝分析物，基本上冲洗来自测试样品的所有剩余废物，以及检测低浓度的分析物 。 物种移动是由赋予相反介电电泳力的模块阵列引起的。 模块阵列包括具有连接微流体废物通道的多个微流体通道，用于将不期望的材料引导离开分析物。 施加电场使得分析物具有正的介电电泳力以捕获分析物。 通过用参比溶液冲洗分析物来改变分析物的克劳修斯 - 莫索蒂（Clausius-Mossotti）因子，这引起负介电电泳力以促进分析物的释放。 场效应纳米线或纳米纤维传感器在捕获后检测分析物。

    System and method for trapping and measuring a charged particle in a liquid
    5.
    发明授权
    System and method for trapping and measuring a charged particle in a liquid 有权
    捕集和测量液体中带电粒子的系统和方法

    公开(公告)号：US08294092B2

    公开(公告)日：2012-10-23

    申请号：US12730226

    申请日：2010-03-23

    申请人： Mark A. Reed ,  Predrag S. Krstic ,  Weihua Guan ,  Xiongce Zhao

    发明人： Mark A. Reed ,  Predrag S. Krstic ,  Weihua Guan ,  Xiongce Zhao

    IPC分类号： B01D59/44

    CPC分类号： G01N33/48721

    摘要： A system and method for trapping a charged particle is disclosed. A time-varying periodic multipole electric potential is generated in a trapping volume. A charged particle under the influence of the multipole electric field is confined to the trapping volume. A three electrode configuration giving rise to a 3D Paul trap and a four planar electrode configuration giving rise to a 2D Paul trap are disclosed.

    摘要翻译： 公开了一种用于捕获带电粒子的系统和方法。 在捕集体积中产生时变周期性多极电位。 在多极电场影响下的带电粒子被限制在捕获体积上。 公开了产生3D保护陷阱的三电极配置和引起2D保护陷阱的四个平面电极配置。

    Spear gun sight assembly
    8.
    发明授权
    Spear gun sight assembly 失效
    矛枪组装

    公开(公告)号：US07043864B1

    公开(公告)日：2006-05-16

    申请号：US10960841

    申请日：2004-10-08

    申请人： Mark A. Reed

    发明人： Mark A. Reed

    IPC分类号： F41G1/00 ,  F41G1/02 ,  F41G1/06

    CPC分类号： F41G1/01 ,  F41G1/08 ,  F41G1/22 ,  F41G1/46

    摘要： A spear gun sight assembly includes a rear sight with a first plate having a generally perpendicular bend therein such that a vertically orientated lower portion and a horizontally orientated upper portion are defined. A peep sight is attached to and extends upwardly from a top side of the upper portion. The peep sight has a peephole extending therethrough. A first coupler is adapted for releasably securing the rear sight to a spear gun. A front sight includes a second plate that has an inner side and an outer side. A loop is attached to the second plate so that the loop extends away from the inner side. A sight pin is attached to the second plate and extends into the loop. A second coupler is adapted for releasably securing the front sight to the spear gun so that the peephole is aligned with the sight pin.

    摘要翻译： 枪枪瞄准器组件包括后视镜，其具有在其中具有大致垂直弯曲的第一板，使得限定了垂直定向的下部和水平定向的上部。 窥视瞄准器从上部的顶侧附接并向上延伸。 窥视视野具有延伸穿过其中的窥视孔。 第一联接器适于将后视野可释放地固定在矛枪上。 前视镜包括具有内侧和外侧的第二板。 环路附接到第二板，使得环路从内侧延伸。 瞄准器连接到第二板并延伸到环中。 第二联接器适于将前视野释放地固定到矛枪上，使得窥视孔与瞄准器对准。