公开(公告)号：US20130330090A1

公开(公告)日：2013-12-12

申请号：US14001075

申请日：2012-02-24

申请人： Akira Obika ,  Masayuki Kitagawa

发明人： Akira Obika ,  Masayuki Kitagawa

IPC分类号： H04B10/50

CPC分类号： H04B10/503 ,  H01S5/005 ,  H01S5/02228 ,  H01S5/0228 ,  H01S5/02296 ,  H01S5/0683 ,  H01S5/183

摘要： A communication module according to the present invention includes a substrate, a laser element and a light receiving element provided on a front surface of the substrate and separating from each other, a transparent resin package collectively sealing the laser element and the light receiving element, and a diffusion unit provided to be opposed to a light emitting surface of the laser element at a prescribed distance for diffusing a laser beam emitted by the laser element, while the distance T between the laser element and the light receiving element satisfies the following formula (1): T≧t1·tan θ+(t1+t2)·tan θ′ . . . (1) (in the formula (1), t1 represents the distance between the light emitting surface of the laser element and the diffusion unit, θ represents the maximum angle of emission of the laser element, t2 represents the difference between the height from the front surface of the substrate up to the light emitting surface and the height up to alight receiving surface of the light receiving element, and θ′ represents the maximum diffusion angle of the diffusion unit.)

摘要翻译： 根据本发明的通信模块包括：基板，激光元件和设置在基板的前表面上的光接收元件，彼此分离，一体地密封激光元件和光接收元件的透明树脂封装;以及 扩散单元，设置成与激光元件的发光面相对规定距离，用于扩散由激光元件发射的激光束，而激光元件和光接收元件之间的距离T满足下式（1 ）：T> = t1·tanθ+（t1 + t2）·tanθ'。 。 。 （1）（式（1）中，t1表示激光元件的发光面与扩散单元之间的距离，θ表示激光元件的最大发射角，t2表示与 衬底的前表面直到发光表面和高度接近光接收元件的接收表面，θ'表示扩散单元的最大扩散角。）

公开(公告)号：US20100004403A1

公开(公告)日：2010-01-07

申请号：US12309061

申请日：2007-07-13

申请人： Masayuki Kitagawa ,  Keizou Ishikawa ,  Akira Masuda ,  Kazutoshi Takashio

发明人： Masayuki Kitagawa ,  Keizou Ishikawa ,  Akira Masuda ,  Kazutoshi Takashio

IPC分类号： C08L71/02

CPC分类号： C08G73/1092 ,  A61K47/60 ,  A61K47/645

摘要： A novel derivative of combretastatins which has water solubility and is capable of releasing the drug independent of biological enzymes likely to cause individual differences and whose effective therapeutic effect can be expected has been demanded. A high-molecular weight conjugate of combretastatins, characterized by having a structure in which a hydroxyl group of a combretastatin is linked via an ester bond to a carboxylic acid group of the polymer moiety in a block copolymer of a polyethylene glycol moiety with the polymer moiety having two or more carboxylic acid groups such as polyaspartic acid or polyglutamic acid is provided.

摘要翻译： 已经要求具有水溶性并且能够释放药物的新型衍生物，其独立于可能导致个体差异的生物酶，并且可以预期其有效的治疗效果。 考布斯他汀的高分子量缀合物，其特征在于具有以下结构：考布他汀的羟基通过酯键与聚乙烯部分与聚合物部分的嵌段共聚物中的聚合物部分的羧酸基团连接 提供具有两个或更多个羧酸基团，例如聚天冬氨酸或聚谷氨酸。

公开(公告)号：US06708231B1

公开(公告)日：2004-03-16

申请号：US09372485

申请日：1999-08-12

申请人： Masayuki Kitagawa

发明人： Masayuki Kitagawa

IPC分类号： G06F1136

CPC分类号： G06F8/65

摘要： The present invention provides systems and methods for performing a firmware update. In one embodiment, a peripheral reset signal is masked in response to a peripheral firmware update command. The firmware update is loaded into a peripheral's nonvolatile memory while the reset signal is masked.

摘要翻译： 本发明提供了用于执行固件更新的系统和方法。 在一个实施例中，响应于外围固件更新命令掩蔽外围复位信号。 当复位信号被屏蔽时，固件更新被加载到外设的非易失性存储器中。

公开(公告)号：US06618216B2

公开(公告)日：2003-09-09

申请号：US09116721

申请日：1998-07-16

申请人： Masayuki Kitagawa

发明人： Masayuki Kitagawa

IPC分类号： G11B1514

CPC分类号： G11B20/10009 ,  G11B5/0086 ,  G11B5/035 ,  G11B5/09 ,  G11B2005/001 ,  G11B2005/0013

摘要： One aspect of the invention is a digital audio tape (DAT) drive having a plurality of read and write heads. Each of the read and write heads has its own parameters, such as a cut-off frequency and a boost value of a read head, a write current of a write head, etc. The parameters of each head are stored in registers and used when an electrical signal representing digital data is to be written to or read from a magnetic tape is processed. When the electrical signal to be written or to have been read by a specific head is processed, the parameters of the specific head will be provided to an equalizer or a pre-amplifier. In the reading process, because the optimum cut-off frequency and boost value are used for a specific read head, the processed electrical signal more accurately represents the digital data recorded on the magnetic tape. In the writing process, the optimum write current to a specific write head makes the write head generate a sufficient magnetic field to magnetize the write head. Therefore, the reliability of read and write operations of a DAT drive is greatly improved.

摘要翻译： 本发明的一个方面是具有多个读写头的数字音频磁带（DAT）驱动器。 每个读写头具有其自己的参数，诸如读取头的截止频率和升压值，写入头的写入电流等。每个头部的参数被存储在寄存器中并在 表示数字数据的电信号被写入或从磁带读取被处理。 当要写入或被特定头读取的电信号被处理时，特定头的参数将被提供给均衡器或前置放大器。 在读取过程中，由于将最佳截止频率和升压值用于特定的读取头，所以处理的电信号更准确地表示记录在磁带上的数字数据。 在写入过程中，对特定写入头的最佳写入电流使得写入头产生足够的磁场来磁化写入头。 因此，DAT驱动器的读写操作的可靠性大大提高。

公开(公告)号：US06603676B2

公开(公告)日：2003-08-05

申请号：US10268472

申请日：2002-10-10

申请人： Masayuki Kitagawa

发明人： Masayuki Kitagawa

IPC分类号： G11C1300

CPC分类号： G06F3/0605 ,  G06F3/0632 ,  G06F3/0677

摘要： A method of writing in or reading out data on a medium is provided. The method comprises receiving mechanism driving information corresponding to a type of a drive unit from an external apparatus, the drive unit being configured to write in or read out data on a medium. The method also comprises storing the mechanism driving information, and providing the stored mechanism driving information to the drive unit for activation.

摘要翻译： 提供了一种在介质上写入或读出数据的方法。 该方法包括从外部装置接收对应于驱动单元的类型的机构驱动信息，所述驱动单元被配置为在介质上写入或读出数据。 该方法还包括存储机构驱动信息，以及将所存储的机构驱动信息提供给驱动单元进行激活。

公开(公告)号：US5505944A

公开(公告)日：1996-04-09

申请号：US392841

申请日：1995-02-28

申请人： Tomio Morino ,  Ayako Nakatani ,  Masayuki Kitagawa ,  Masaya Sato ,  Takashi Harada ,  Seiichi Saito

发明人： Tomio Morino ,  Ayako Nakatani ,  Masayuki Kitagawa ,  Masaya Sato ,  Takashi Harada ,  Seiichi Saito

IPC分类号： C12P1/06 ,  C07G17/00 ,  C12P1/04 ,  A61K35/74 ,  C12N1/20

CPC分类号： C12P1/06 ,  Y10S435/886

摘要： Physiologically active substance NK175203 is produced by culturing bacteria belonging to the genus Streptomyces and capable of producing the physiologically active substance NK175203, and collecting the produced and accumulated substance. The physiologically active substance NK175203 is useful as an effective ingredient of a pharmaceutical composition for promoting proliferation of bone marrow cells.

摘要翻译： PCT No.PCT / JP93 / 01276 Sec。 371日期1995年2月28日 102（e）1995年2月28日PCT PCT 1993年9月8日PCT公布。 出版物WO94 / 05679 日期：1994年3月17日。生理活性物质NK175203是通过培养属于链霉菌属的细菌产生的，能够生产生理活性物质NK175203，并收集生成和积累的物质。 生理活性物质NK175203可用作促进骨髓细胞增殖的药物组合物的有效成分。

公开(公告)号：US5450251A

公开(公告)日：1995-09-12

申请号：US234113

申请日：1994-04-28

申请人： Masayuki Kitagawa

发明人： Masayuki Kitagawa

IPC分类号： G11B20/10 ,  G11B20/12 ,  G11B20/18 ,  G11B27/10 ,  G11B27/30 ,  G11B5/09

CPC分类号： G11B20/1883 ,  G11B27/3027 ,  G11B2220/20

摘要： In a magnetic disc apparatus having data tracks, relocation tracks, and data-saving tracks, each track of these tracks has sectors composed of an identifier and a data part. An identifier includes a logical sector address and flags. And relocation is performed in a sector unit(not in a track unit), and identifiers are used for data identification in relocation.

摘要翻译： 在具有数据轨道，重定位轨道和数据保存轨道的磁盘装置中，这些轨道的每个轨道具有由标识符和数据部分组成的扇区。 标识符包括逻辑扇区地址和标志。 并且在扇区单元（不在轨道单元中）执行重定位，并且在重定位中使用标识符用于数据标识。

公开(公告)号：US20120116051A1

公开(公告)日：2012-05-10

申请号：US13319175

申请日：2010-05-12

申请人： Masayuki Kitagawa ,  Chieko Seno ,  Keiko Ebara ,  Kazutoshi Takashio

发明人： Masayuki Kitagawa ,  Chieko Seno ,  Keiko Ebara ,  Kazutoshi Takashio

IPC分类号： C08H1/00 ,  A61P9/10 ,  A61P17/14 ,  A61P29/00 ,  A61P35/00

CPC分类号： C08G69/10 ,  A61K31/167 ,  A61K31/19 ,  A61K31/195 ,  A61K31/337 ,  A61K31/365 ,  A61K31/4745 ,  A61K31/52 ,  A61K31/573 ,  A61K31/704 ,  A61K31/7052 ,  A61K31/7068 ,  A61K47/60 ,  A61K47/645 ,  C08G69/40 ,  C08G69/48

摘要： A polymer conjugate of a physiologically active substance, which enables drug release independent of a biological enzyme and can be expected to have a high therapeutic effect, is demanded.Provided is a polymer conjugate of a physiologically active substance, comprising a block copolymer of a polyethylene glycol moiety and a polymer having two or more carboxy groups, in which a substituent represented by general formula (I) or general formula (II) is linked to at least one of the side-chain carboxy groups of the block copolymer via an amide bond [in the formula, R8 and R9 each independently are hydrogen atom or (C1-C6)alkyl which may have a substituent, R10 is hydrogen atom, (C1-C40)alkyl which may have a substituent, (C1-C40) aralkyl group which may have a substituent, an aromatic group which may have a substituent, an amino acid residue having a protected carboxy group, or a sugar residue which may have a substituent, CX—CY represents CH—CH or C═C (double bond), and A represents a residue obtained by removing, from a physiologically active substance having one or more hydroxy groups, one of the one or more hydroxy groups].

摘要翻译： 需要生物活性物质的聚合物缀合物，其使药物释放与生物酶无关并且可以预期具有高治疗效果。 提供了一种生理活性物质的聚合物缀合物，其包含聚乙二醇部分和具有两个或更多个羧基的聚合物的嵌段共聚物，其中由通式（I）或通式（II）表示的取代基与 嵌段共聚物中的至少一个侧链羧基通过酰胺键[在式中，R8和R9各自独立地为氢原子或可具有取代基的（C1-C6）烷基，R10为氢原子（ 可以具有取代基的C 1 -C 40的烷基，可以具有取代基的（C 1〜C 40）芳烷基，可以具有取代基的芳香族基，具有被保护的羧基的氨基酸残基， 取代基，CX-CY表示CH-CH或C = C（双键），A表示通过从具有一个或多个羟基的生理活性物质除去一个或多个羟基之一而获得的残基]。

公开(公告)号：US20100234537A1

公开(公告)日：2010-09-16

申请号：US12225230

申请日：2007-03-22

申请人： Masayuki Kitagawa ,  Keizou Ishikawa ,  Takeshi Onda

发明人： Masayuki Kitagawa ,  Keizou Ishikawa ,  Takeshi Onda

IPC分类号： C08G69/48

CPC分类号： C08G65/33324 ,  A61K31/337 ,  A61K47/60 ,  A61K47/645 ,  C08G65/329 ,  C08G69/10 ,  C08G69/40 ,  C08G69/48 ,  C08L2203/02

摘要： [Problems] To provide a novel taxane derivative which can release the medicinal substance in a bioenzyme-independent manner, is expected to have an effective therapeutic efficacy, and has a water-solubility.[Means for Solving Problems] Disclosed is a polymer conjugate of a taxane, which comprises a polymer having a polyethylene glycol moiety and two or more succinic acid monoamide moieties and a taxane, wherein a carboxylate group in the polymer and an alcoholic hydroxyl group in the taxane are bound to each other via an ester bonding.

摘要翻译： [问题]为了提供能够以不依赖生物酶的方式释放药物的新型紫杉烷衍生物，预期具有有效的治疗功效，并且具有水溶性。 解决问题的手段公开了紫杉烷的聚合物缀合物，其包含具有聚乙二醇部分和两个或多个琥珀酸单酰胺部分的聚合物和紫杉烷，其中聚合物中的羧酸酯基团和 紫杉烷通过酯键相互结合。

公开(公告)号：US4841076A

公开(公告)日：1989-06-20

申请号：US58105

申请日：1987-06-04

申请人： Masayuki Kitagawa ,  Makoto Tanaka

发明人： Masayuki Kitagawa ,  Makoto Tanaka

IPC分类号： A61K31/35 ,  A61K31/352 ,  A61K31/353 ,  A61K31/40 ,  A61K31/41 ,  A61K31/443 ,  A61K31/445 ,  A61K31/495 ,  A61K31/535 ,  A61K31/54 ,  A61P7/10 ,  A61P9/12 ,  A61P19/06 ,  C07D311/22 ,  C07D311/26 ,  C07D311/28 ,  C07D311/30 ,  C07D311/32 ,  C07D311/34 ,  C07D311/36 ,  C07D311/38 ,  C07D311/62 ,  C07D405/04 ,  C07D405/12 ,  C07D413/04 ,  C07D417/04

CPC分类号： C07D311/22 ,  C07D311/36 ,  C07D311/38

摘要： A benzopyran derivative represented by formula ##STR1## wherein: R.sub.1 and R.sub.2 each represents a hydrogen atom, a lower alkyl group, a substituted or unsubstituted cyclic alkyl group, a mono- or di-lower alkylamino group, a substituted or unsubsituted cyclic amino group, a substituted or unsubstituted aryl group, or a substituted or unsubstituted aralkyl group;Y.sub.1 and Y.sub.2 each represents a hydrogen atom, a lower alkyl group, a halogen atom or a trihalomethyl group;Z represents a caroxyl group, a lower alkoxy-carbonyl group, a tetrazolyl group, a hydroxyl group or --CONR.sub.3 R.sub.4 wherein R.sub.3 and R.sub.4 each represents a hydrogen atom or a lower alkyl group;n represents an integer of from 1 to 6; andthe bond between the 2- and 3-positions represents a single bond or a double bond;provided that a combination wherein Y.sub.1, Y.sub.2, and R.sub.2 each represents a hydrogen atom, R.sub.1 represents a phenyl group, n represents 1, Z represents a carboxyl group or an alkoxycarbonyl group, and the bond represents a double bond, and a combination wherein Y.sub.1, Y.sub.2, and R.sub.1 each represents a hydrogen atom, R.sub.2 represents a phenyl group, n represents 1, Z represents a carboxyl group or an alkoxy-carbonyl group, and the bond represents a double bond are excluded, and pharmaceutically acceptable salts thereof are disclosed. These compounds have uricosuric activity, diuretic activity and antihypertensive activity, and are useful as pharmaceuticals.

摘要翻译： 由式表示的苯并吡喃衍生物其中：R1和R2各自表示氢原子，低级烷基，取代或未取代的环状烷基，一或二低级烷基氨基，取代或未取代的环状氨基 取代或未取代的芳基或取代或未取代的芳烷基; Y1和Y2各自表示氢原子，低级烷基，卤素原子或三卤代甲基; Z表示羧酸基，低级烷氧基 - 羰基，四唑基，羟基或-CONR 3 R 4，其中R 3和R 4各自表示氢原子或低级烷基; n表示1〜6的整数， 并且2-和3-位之间的键表示单键或双键; 条件是其中Y1，Y2和R2各自表示氢原子，R1表示苯基，n表示1，Z表示羧基或烷氧基羰基，键表示双键的组合，其中Y1 ，Y2和R1各自表示氢原子，R2表示苯基，n表示1，Z表示羧基或烷氧基 - 羰基，并且该键代表双键，并且其公开的药学上可接受的盐被公开 。 这些化合物具有尿酸活性，利尿活性和抗高血压活性，并且可用作药物。