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公开(公告)号：US08722327B2
公开(公告)日：2014-05-13
申请号：US12057987
申请日：2008-03-28
CPC分类号： C12Q1/6874 , B01L3/50273 , B01L3/502761 , B01L2200/0663 , B01L2200/0668 , B01L2200/12 , B01L2300/041 , B01L2300/0627 , B01L2300/0654 , B01L2300/0816 , B01L2300/0861 , B01L2300/0864 , B01L2300/0887 , B01L2300/089 , B01L2300/0896 , B01L2300/161 , B01L2400/0406 , B01L2400/0415 , B01L2400/0487 , B01L2400/086 , C12Q1/6876 , C12Q2563/107 , C12Q2600/172 , G01N21/6428 , G01N21/645 , G01N33/582
摘要： Methods of analyzing features such as the physical size of macromolecules or biomarkers along large genomic DNA molecules were disclosed as well as the devices for carrying out such high throughput analysis in a massively parallel fashion. Methods of fabricating such devices are also disclosed.
摘要翻译： 公开了分析诸如大基因组DNA分子之间的大分子或生物标记的物理尺寸等特征的方法以及以大规模并行方式进行这种高通量分析的装置。 还公开了制造这种装置的方法。
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2.发明申请INTEGRATED ANALYSIS DEVICES AND RELATED FABRICATION METHODS AND ANALYSIS TECHNIQUES 有权综合分析设备及相关制造方法与分析技术公开(公告)号：US20110296903A1
公开(公告)日：2011-12-08
申请号：US12996410
申请日：2009-06-05
申请人： Han Cao , Michael D. Austin , Parikshit A. Deshpande , Mark Kunkel , Alexey Y. Sharonov , Michael Kochersperger
发明人： Han Cao , Michael D. Austin , Parikshit A. Deshpande , Mark Kunkel , Alexey Y. Sharonov , Michael Kochersperger
CPC分类号： B81C1/00119 , B01L3/502761 , B01L2200/0663 , B01L2200/0689 , B01L2200/10 , B01L2300/0816 , B01L2300/0851 , B01L2300/0858 , B01L2300/0864 , B01L2300/0887 , B01L2300/168 , B01L2400/0415 , B01L2400/043 , B01L2400/0442 , B01L2400/0487 , B01L2400/086 , B81B2201/058 , B81C2201/019 , G01N2021/0346 , G01N2021/6439 , Y10T29/4981
摘要： Provided are integrated analysis devices having features of macroscale and nanoscale dimensions, and devices that have reduced background signals and that reduce quenching of fluorophores disposed within the devices. Related methods of manufacturing these devices and of using these devices are also provided.
摘要翻译： 提供了具有宏观尺寸和纳米级尺寸特征的集成分析装置，以及具有降低的背景信号并且减少设置在装置内的荧光团的淬灭的装置。 还提供了制造这些装置和使用这些装置的相关方法。
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3.发明授权Nanonozzle device arrays: their preparation and use for macromolecular analysis 有权Nanonozzle器件阵列：它们的制备和用于大分子分析公开(公告)号：US09061901B2
公开(公告)日：2015-06-23
申请号：US12374141
申请日：2007-07-19
IPC分类号： C12M1/34 , C12Q1/68 , G01N15/06 , G01N21/00 , C07H21/02 , B82Y30/00 , B01L3/00 , G01N33/487 , G01N35/10
CPC分类号： B82Y30/00 , B01L3/502761 , B01L2200/0663 , B01L2200/12 , B01L2300/0645 , B01L2300/0816 , B01L2300/0822 , B01L2300/0896 , B01L2400/0415 , B01L2400/0487 , C12Q1/6869 , G01N27/447 , G01N33/48721 , G01N2035/1039 , Y10T436/143333 , Y10T436/2575 , C12Q2565/631
摘要： Constricted nanochannel devices suitable for use in analysis of macromolecular structure, including DNA sequencing, are disclosed. Also disclosed are methods for fabricating such devices and for analyzing macromolecules using such devices.
摘要翻译： 公开了适用于分析大分子结构（包括DNA测序）的约束纳米通道器件。 还公开了制造这种装置和使用这种装置分析大分子的方法。
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4.发明申请NANONOZZLE DEVICE ARRAYS: THEIR PREPARATION AND USE FOR MACROMOLECULAR ANALYSIS 有权纳米器件阵列：其制备和用于大分子分析公开(公告)号：US20090305273A1
公开(公告)日：2009-12-10
申请号：US12374141
申请日：2007-07-19
CPC分类号： B82Y30/00 , B01L3/502761 , B01L2200/0663 , B01L2200/12 , B01L2300/0645 , B01L2300/0816 , B01L2300/0822 , B01L2300/0896 , B01L2400/0415 , B01L2400/0487 , C12Q1/6869 , G01N27/447 , G01N33/48721 , G01N2035/1039 , Y10T436/143333 , Y10T436/2575 , C12Q2565/631
摘要： Constricted nanochannel devices suitable for use in analysis of macromolecular structure, including DNA sequencing, are disclosed. Also disclosed are methods for fabricating such devices and for analyzing macro-molecules using such devices.
摘要翻译： 公开了适用于分析大分子结构（包括DNA测序）的约束纳米通道装置。 还公开了制造这种装置并用于使用这种装置分析大分子的方法。
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5.发明授权Integrated analysis devices and related fabrication methods and analysis techniques 有权综合分析装置及相关制造方法和分析技术公开(公告)号：US09533879B2
公开(公告)日：2017-01-03
申请号：US12996410
申请日：2009-06-05
申请人： Han Cao , Michael D. Austin , Parikshit A. Deshpande , Mark Kunkel , Alexey Y. Sharonov , Michael Kochersperger
发明人： Han Cao , Michael D. Austin , Parikshit A. Deshpande , Mark Kunkel , Alexey Y. Sharonov , Michael Kochersperger
CPC分类号： B81C1/00119 , B01L3/502761 , B01L2200/0663 , B01L2200/0689 , B01L2200/10 , B01L2300/0816 , B01L2300/0851 , B01L2300/0858 , B01L2300/0864 , B01L2300/0887 , B01L2300/168 , B01L2400/0415 , B01L2400/043 , B01L2400/0442 , B01L2400/0487 , B01L2400/086 , B81B2201/058 , B81C2201/019 , G01N2021/0346 , G01N2021/6439 , Y10T29/4981
摘要： Provided are integrated analysis devices having features of macroscale and nanoscale dimensions, and devices that have reduced background signals and that reduce quenching of fluorophores disposed within the devices. Related methods of manufacturing these devices and of using these devices are also provided.
摘要翻译： 提供了具有宏观尺寸和纳米级尺寸特征的集成分析装置，以及具有降低的背景信号并且减少设置在装置内的荧光团的淬灭的装置。 还提供了制造这些装置和使用这些装置的相关方法。
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公开(公告)号：US20080242556A1
公开(公告)日：2008-10-02
申请号：US12057987
申请日：2008-03-28
CPC分类号： C12Q1/6874 , B01L3/50273 , B01L3/502761 , B01L2200/0663 , B01L2200/0668 , B01L2200/12 , B01L2300/041 , B01L2300/0627 , B01L2300/0654 , B01L2300/0816 , B01L2300/0861 , B01L2300/0864 , B01L2300/0887 , B01L2300/089 , B01L2300/0896 , B01L2300/161 , B01L2400/0406 , B01L2400/0415 , B01L2400/0487 , B01L2400/086 , C12Q1/6876 , C12Q2563/107 , C12Q2600/172 , G01N21/6428 , G01N21/645 , G01N33/582
摘要： Methods of analyzing features such as the physical size of macromolecules or biomarkers along large genomic DNA molecules were disclosed as well as the devices for carrying out such high throughput analysis in a massively parallel fashion. Methods of fabricating such devices are also disclosed.
摘要翻译： 公开了分析诸如大基因组DNA分子之间的大分子或生物标记的物理尺寸等特征的方法以及以大规模并行方式进行这种高通量分析的装置。 还公开了制造这种装置的方法。
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公开(公告)号：US06598540B2
公开(公告)日：2003-07-29
申请号：US09767118
申请日：2001-01-22
IPC分类号： B65D1900
CPC分类号： B65D19/385 , B65D19/38 , B65D19/44 , B65D2519/00174 , B65D2519/00208 , B65D2519/00273 , B65D2519/00293 , B65D2519/00323 , B65D2519/00343 , B65D2519/00497 , B65D2519/00606 , B65D2519/00701 , B65D2519/00726 , B65D2519/00796 , B65D2519/00815 , B65D2519/0097
摘要： A pallet cover has a top panel and side panels hinged to the top panel for swinging movements from a substantially vertical position depending from the top panel through an arc sufficient to enable each side panel to overlie the top panel. The pallet is provided with supports which enable it to be stacked with one or more other pallets and the cover is notched to accommodate the stacking supports and provide an interlock therewith to ensure retention of the cover on the associated pallet.
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公开(公告)号：US5643615A
公开(公告)日：1997-07-01
申请号：US401763
申请日：1995-03-10
申请人： Michael D. Austin
发明人： Michael D. Austin
CPC分类号： B30B15/028 , B21D37/14 , B21D43/05
摘要： Die presses containing removable dies and arranged in a row for operating successively on a workpiece which traverses such row utilize movable die carts which not only are capable of substituting one set of dies for the dies in the presses, but which also effect transfer of workpieces between successive presses.
摘要翻译： 包含可拆卸模具的模压机并排布置成连续地在穿过这种排的工件上运行，其使用可移动模具车，其不仅能够将一组模具用于冲压机中的模具，而且还可以实现工件之间的转移 连续印刷机。
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