Removable microfluidic flow cell
    1.
    发明授权
    Removable microfluidic flow cell 有权
    可移动微流体流动池

    公开(公告)号:US08444934B2

    公开(公告)日:2013-05-21

    申请号:US10593990

    申请日:2005-03-29

    申请人: Regis Peytavi

    发明人: Regis Peytavi

    IPC分类号: B01J19/00

    摘要: A microfluidic flow cell for removably interfacing with a removable-member for performing a reaction therebetween. The microfluidic flow cell device comprises at least one reaction portion defining with the removable-member a reaction chamber when in an interfaced position thereof. The microfluidic flow cell comprises at least one fluid-receiving portion for receiving a fluid therein and being in fluid communication with the reaction chamber. When the microfluidic flow cell and the removable-member are in the interfaced position, the cell is adapted to allow for the fluid in the fluid-receiving portion to flow to the reaction chamber. Devices, systems and methods comprising this microfluidic flow cell are also disclosed.

    摘要翻译: 一种微流体流动池,用于与可移除构件可移除地相互连接,用于在其间进行反应。 微流体流动池装置包括至少一个反应部分,该反应部分在其可接合位置处与可移除部件一起形成反应室。 微流体流动池包括用于在其中接收流体并与反应室流体连通的至少一个流体接收部分。 当微流体流动池和可移除构件处于接合位置时,电池适于允许流体接收部分中的流体流动到反应室。 还公开了包括该微流体流动池的装置,系统和方法。

    Removable microfluidic cell
    4.
    发明申请
    Removable microfluidic cell 有权
    可移除微流体细胞

    公开(公告)号:US20090023610A1

    公开(公告)日:2009-01-22

    申请号:US10593990

    申请日:2005-03-29

    申请人: Regis Peytavi

    发明人: Regis Peytavi

    IPC分类号: C40B60/12 B01J19/00

    摘要: A microfluidic flow cell for removably interfacing with a removable-member for performing a reaction therebetween. The microfluidic flow cell device comprises at least one reaction portion defining with the removable-member a reaction chamber when in an interfaced position thereof. The microfluidic flow cell comprises at least one fluid-receiving portion for receiving a fluid therein and being in fluid communication with the reaction chamber. When the microfluidic flow cell and the removable-member are in the interfaced position, the cell is adapted to allow for the fluid in the fluid-receiving portion to flow to the reaction chamber. Devices, systems and methods comprising this microfluidic flow cell are also disclosed.

    摘要翻译: 一种微流体流动池,用于与可移除构件可移除地相互连接,用于在其间进行反应。 微流体流动池装置包括至少一个反应部分,该反应部分在其可接合位置处与可移除部件一起形成反应室。 微流体流动池包括用于在其中接收流体并与反应室流体连通的至少一个流体接收部分。 当微流体流动池和可移除构件处于接合位置时,电池适于允许流体接收部分中的流体流动到反应室。 还公开了包括该微流体流动池的装置,系统和方法。

    Capture Probe Design for Efficient Hybridisation
    7.
    发明申请
    Capture Probe Design for Efficient Hybridisation 审中-公开
    捕获探针设计高效杂交

    公开(公告)号:US20080305966A1

    公开(公告)日:2008-12-11

    申请号:US11573183

    申请日:2005-06-30

    IPC分类号: C40B40/06 C07H21/04 G01N33/50

    摘要: Methods for selecting and designing optimal nucleic acid-based probe for improving the sensitivity of detection of a nucleic acid-based target are disclosed herein. The capture probes generated from these methods show a significant improvement in the sensitivity of detection. Improved probes as well as microarrays and kits comprising these probes are disclosed herewith.

    摘要翻译: 本文公开了选择和设计用于提高基于核酸的靶的检测灵敏度的基于核酸的最佳探针的方法。 从这些方法产生的捕获探针显示出检测灵敏度的显着改善。 本文公开了改进的探针以及包含这些探针的微阵列和试剂盒。

    System for charge-based detection of nucleic acids
    8.
    发明申请
    System for charge-based detection of nucleic acids 审中-公开
    核酸电荷检测系统

    公开(公告)号:US20070178470A1

    公开(公告)日:2007-08-02

    申请号:US10596397

    申请日:2004-12-13

    IPC分类号: C12Q1/68 C12M1/34

    摘要: This present invention relates methods for detecting the presence of nucleic acids in a sample. In these methods, neutral capture probes are exposed to a sample possibly containing complementary nucleic acid targets. The foregoing mixture is submitted to conditions that provide for the nucleic acid targets to bind with the neutral probes thereby generating hybrids. These hybrids are submitted to positively charged reporters such as atoms, molecules or macromolecules, which electrostatically bind to the hybrids. The complexes formed between reporters and hybrids are detected by a variety of detection methods. Kits for detecting the presence of nucleic acids in a sample are also disclosed herein.

    摘要翻译: 本发明涉及检测样品中核酸存在的方法。 在这些方法中,中性捕获探针暴露于可能含有互补核酸靶的样品。 前述混合物被提供到使核酸靶标与中性探针结合从而产生杂交体的条件。 这些杂交体被提交给带正电荷的记录,例如原子,分子或大分子,其静电结合到杂交体上。 通过各种检测方法检测记者与杂交体之间形成的复合物。 本文还公开了用于检测样品中核酸存在的试剂盒。