摘要:
The invention relates to antibodies specific to human CK8 and to pharmaceutical compositions for preventing and treating colorectal cancers. The invention also relates to methods for identifying colorectal cancers with an invasive and/or metastatic phenotype including detecting the cleavage of the C-terminal portion of human CK8 on the surface of tumour cells.
摘要:
The invention relates to a device for filling at least one receptacle (12) of gel card type initially sealed by a cap. The invention is characterized by the fact that the filling device comprises a piercing member (110) for perforating the cap, means (120) for eliminating the electrostatic charges capable of being borne by the receptacle, and filling means (130) for filling the receptacle after perforation of the cap and elimination of the electrostatic charges.
摘要:
A regimen for inducing/stimulating hair growth and/or retarding hair loss on an individual in need of such treatment comprises topically applying to the affected hair and/or scalp of such individual, a hair growth stimulating and/or hair loss retarding effective amount of at least one 2,3-dihydroxypropyl-2-(1-oxohydrocarbyl) amino-2-deoxyglucopyranoside having the structural formula: ##STR1## in which R is a linear or branched, saturated or unsaturated hydrocarbon radical having from 5 to 21 carbon atoms.
摘要:
The invention relates to compounds of formula: ##STR1## The invention also relates to a process for the preparation of the said compounds, which consists in: a) reacting dianhydro-1,4:3,6-D-glucitol with a compound of formula RCOOR' or RCH.sub.2 Y in the presence of a catalyst to form compounds of formula: ##STR2## in which: Y represents a halogen or an alkyl or arylsulfonic radical, R' represents a hydrogen atom or an alkyl radical having from 1 to 6 carbon atoms, R represents a saturated or unsaturated linear or branched alkyl radical containing from 5 to 21 carbon atoms, x represents CO or CH.sub.2 ; b) reacting the product of step a) with phosphorus oxychloride, a base and an anhydrous solvent, to form the compounds of formula (I) and/or (II), and optionally in separating them. The compounds which form the subject of the invention can be used in the field of surfactants, in particular for the preparation of cosmetic or hair compositions.
摘要:
The invention relates to cleavable surfactants of formula: in which R′ and R, which may be identical or different, represent a hydrogen atom or a linear or branched, saturated or unsaturated alkyl radical, the sum of the carbon atoms of R′ and R being between 5 and 42. The invention also relates to the corresponding derivatives obtained by alkaline hydrolysis or amidation. The invention furthermore relates to the preparation of these surfactants from glucono-1(5)-lactone and a compound of formula R—CO—R′ in the presence of an acid catalyst, R and R′ having the meaning given above. The surfactants are used in particular in emulsion polymerization and in the field of cosmetics.
摘要:
The invention relates to fluoroalkyl derivatives of uronic acids of the formula: ##STR1## and the corresponding lactones, as well as a process for the preparation of the said compounds, which comprises reacting a glycosiduronic acid or a glycosiduronolactone with an alcohol of formula R.sub.1 OH, which process may also include steps of basiciation and acidification. The compounds according to the invention may be used in particular as surfactants.
摘要:
The invention relates to antibodies specific to human CK8 and to pharmaceutical compositions for preventing and treating colorectal cancers. The invention also relates to methods for identifying colorectal cancers with an invasive and/or metastatic phenotype including detecting the cleavage of the C-terminal portion of human CK8 on the surface of tumor cells.
摘要:
A converter for an electric motor or transformer, the converter being comprising a connection box having passages for electrical conductors and having a semiconductor electronic module removably fixed to the connection box. The electronic module has a radiator-forming box that is open at one end, at least one electronic card at least partially embedded in a resin cast inside said radiator-forming box, and at least one connector emerging from the resin. The opening of the radiator-forming box enables it to be fitted to the connection box. The connection box has at least one window giving access to the connector(s) of the electronic module.
摘要:
Compositions comprising intrinsic factor (IF), and in particular, compositions comprising substantially pure intrinsic factor (IF) and a polypeptide wherein said composition is substantially free of R protein; a method of delivering a composition to the portal and/or lymphatic circulation system of a host; and a method of producing the above-described composition.
摘要:
The galacturonic acid derivatives of formula: ##STR1## R1 being a linear or branched alkyl having 2 to 22 carbon atoms, R being: ##STR2## for which the carbon carrying the hydroxyl group is attached to the endocyclic oxygen atom. R2 being hydrogen, R1, an alkali metal atom, an alkaline-earth metal atom or a quaternary ammonium group of formula: ##STR3## in which R3 to R6 is each independently of the other hydrogen, an alkyl having 1 to 6 carbon atoms or a hydroxyalkyl having 1 to 6 carbon atoms, are surface-active agents.