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    Ultrasound methods of positioning guided vascular access devices in the venous system
    2.
    发明授权
    Ultrasound methods of positioning guided vascular access devices in the venous system 有权
    引导血管通路装置在静脉系统中的超声方法

    公开(公告)号：US08409103B2

    公开(公告)日：2013-04-02

    申请号：US11430511

    申请日：2006-05-08

    申请人： Sorin Grunwald ,  Bradley Hill

    发明人： Sorin Grunwald ,  Bradley Hill

    IPC分类号： A61B8/14

    CPC分类号： A61B34/20 ,  A61B5/02 ,  A61B5/02152 ,  A61B5/06 ,  A61B5/1459 ,  A61B5/7246 ,  A61B5/7271 ,  A61B5/742 ,  A61B8/04 ,  A61B8/06 ,  A61B8/0841 ,  A61B8/12 ,  A61B8/42 ,  A61B8/445 ,  A61B8/4472 ,  A61B8/461 ,  A61B8/488 ,  A61B8/5207 ,  A61B2017/00106 ,  A61B2034/2063 ,  A61B2090/378 ,  G06F19/00

    摘要： The invention relates to the guidance, positioning and placement confirmation of intravascular devices, such as catheters, stylets, guidewires and other flexible elongate bodies that are typically inserted percutaneously into the venous or arterial vasculature. An aspect of the invention includes, for example, an endovenous access and guidance system. The system comprises: an elongate flexible member adapted and configured to access the venous vasculature of a patient; a sensor disposed at a distal end of the elongate flexible member and configured to provide in vivo non-image based ultrasound information of the venous vasculature of the patient; a processor configured to receive and process in vivo non-image based ultrasound information of the venous vasculature of the patient provided by the sensor and to provide position information regarding the position of the distal end of the elongate flexible member within the venous vasculature of the patient; and an output device adapted to output the position information from the processor.

    摘要翻译： 本发明涉及通常经皮插入静脉或动脉脉管系统中的血管内装置（例如导管，样式，导丝和其它柔性细长体）的指导，定位和放置确认。 本发明的一个方面包括例如静脉内进入和引导系统。 该系统包括：细长的柔性构件，其适于和构造成接近病人的静脉血管; 传感器，其设置在所述细长柔性构件的远端处并且被配置为提供所述患者的静脉血管的体内基于非图像的超声信息; 处理器，被配置为接收和处理由传感器提供的患者的静脉血管的体内基于非图像的超声信息，并且提供关于细长柔性构件的远端在患者的静脉血管内的位置的位置信息 ; 以及适于从处理器输出位置信息的输出装置。

    Ultrasound methods of positioning guided vascular access devices in the venous system
    3.
    发明申请
    Ultrasound methods of positioning guided vascular access devices in the venous system 有权
    引导血管通路装置在静脉系统中的超声方法

    公开(公告)号：US20070016068A1

    公开(公告)日：2007-01-18

    申请号：US11430511

    申请日：2006-05-08

    申请人： Sorin Grunwald ,  Bradley Hill

    发明人： Sorin Grunwald ,  Bradley Hill

    IPC分类号： A61B8/14

    CPC分类号： A61B34/20 ,  A61B5/02 ,  A61B5/02152 ,  A61B5/06 ,  A61B5/1459 ,  A61B5/7246 ,  A61B5/7271 ,  A61B5/742 ,  A61B8/04 ,  A61B8/06 ,  A61B8/0841 ,  A61B8/12 ,  A61B8/42 ,  A61B8/445 ,  A61B8/4472 ,  A61B8/461 ,  A61B8/488 ,  A61B8/5207 ,  A61B2017/00106 ,  A61B2034/2063 ,  A61B2090/378 ,  G06F19/00

    摘要： The invention relates to the guidance, positioning and placement confirmation of intravascular devices, such as catheters, stylets, guidewires and other flexible elongate bodies that are typically inserted percutaneously into the venous or arterial vasculature. Currently these goals are achieved using x-ray imaging and in some cases ultrasound imaging. This invention provides a method to substantially reduce the need for imaging related to placing an intravascular catheter or other device. Reduced imaging needs also reduce the amount of radiation that patients are subjected to, reduce the time required for the procedure, and decrease the cost of the procedure by reducing the time needed in the radiology department. An aspect of the invention includes, for example, an endovenous access and guidance system. The system comprises: an elongate flexible member adapted and configured to access the venous vasculature of a patient; a sensor disposed at a distal end of the elongate flexible member and configured to provide in vivo non-image based ultrasound information of the venous vasculature of the patient; a processor configured to receive and process in vivo non-image based ultrasound information of the venous vasculature of the patient provided by the sensor and to provide position information regarding the position of the distal end of the elongate flexible member within the venous vasculature of the patient; and an output device adapted to output the position information from the processor.

    摘要翻译： 本发明涉及通常经皮插入静脉或动脉脉管系统中的血管内装置（例如导管，样式，导丝和其它柔性细长体）的指导，定位和放置确认。 目前，这些目标是使用X射线成像和某些情况下的超声成像实现的。 本发明提供了一种基本上减少与放置血管内导管或其他装置有关的成像的需要的方法。 降低成像需求还可减少患者所遭受的辐射量，减少手术所需的时间，并减少放射科所需时间，从而降低手术成本。 本发明的一个方面包括例如静脉内进入和引导系统。 该系统包括：细长的柔性构件，其适于和构造成接近病人的静脉血管; 传感器，其设置在所述细长柔性构件的远端处并且被配置为提供所述患者的静脉血管的体内非图像基超声信息; 处理器，被配置为接收和处理由传感器提供的患者的静脉血管的体内基于非图像的超声信息，并且提供关于细长柔性构件的远端在患者的静脉脉管系统内的位置的位置信息 ; 以及适于从处理器输出位置信息的输出装置。

    User interface for handheld imaging devices
    4.
    发明授权
    User interface for handheld imaging devices 有权
    用于手持成像设备的用户界面

    公开(公告)号：US07022075B2

    公开(公告)日：2006-04-04

    申请号：US10697148

    申请日：2003-10-29

    申请人： Sorin Grunwald ,  Robert Stanson ,  Soo Hom ,  Ailya Batool ,  Glen W. McLaughlin

    发明人： Sorin Grunwald ,  Robert Stanson ,  Soo Hom ,  Ailya Batool ,  Glen W. McLaughlin

    IPC分类号： A61B8/14

    CPC分类号： A61B8/4438 ,  A61B8/00 ,  A61B8/06 ,  A61B8/08 ,  A61B8/0833 ,  A61B8/0866 ,  A61B8/13 ,  A61B8/4427 ,  A61B8/4455 ,  A61B8/4472 ,  A61B8/462 ,  A61B8/463 ,  A61B8/465 ,  A61B8/467 ,  A61B8/468 ,  A61B8/469 ,  A61B8/488 ,  G01S7/52084 ,  G01S15/8981 ,  G06F19/00 ,  G16H40/63

    摘要： A Graphical User Interface (GUI) for an ultrasound system. The ultrasound system has operational modes and the GUI has corresponding icons, tabs, and menu items image and information fields. The User Interface (UI) provides several types of graphical elements with intelligent behavior, such as being context sensitive and adaptive, called active objects, for example, tabs, menus, icons, windows of user interaction and data display and an alphanumeric keyboard. In addition the UI may also be voice activated. The UI further provides for a touchscreen for direct selection of displayed active objects. In an embodiment, the UI is for a medical ultrasound handheld imaging instrument. The UI provides a limited set of hard and soft keys with adaptive functionality that can be used with only one hand and potentially with only one thumb.

    摘要翻译： 用于超声系统的图形用户界面（GUI）。 超声系统具有操作模式，GUI具有对应的图标，标签和菜单项图像和信息字段。 用户界面（UI）提供了几种具有智能行为的图形元素，例如上下文敏感和自适应，称为活动对象，例如标签，菜单，图标，用户交互和数据显示的窗口以及字母数字键盘。 此外UI也可能是语音激活。 UI还提供了用于直接选择显示的活动对象的触摸屏。 在一个实施例中，UI是用于医疗超声手持成像仪器。 UI提供了一组有限的硬键和软键，具有自适应功能，可以仅使用一只手，只能使用一个拇指。

    Systems and methods for evaluating objects within an ultrasound image
    5.
    发明授权
    Systems and methods for evaluating objects within an ultrasound image 失效
    用于评估超声图像内的物体的系统和方法

    公开(公告)号：US06514202B2

    公开(公告)日：2003-02-04

    申请号：US09840591

    申请日：2001-04-23

    申请人： Sorin Grunwald

    发明人： Sorin Grunwald

    IPC分类号： A61B800

    CPC分类号： G01S7/52036 ,  A61B8/00 ,  A61B8/12

    摘要： According to the invention, an object in an ultrasound image is characterized by considering various in-vivo object parameters and their variability within the ultrasonic imaging data. Specifically, it is assumed that the object may be defined in terms of statistical properties (or object identifying parameters), which are consistently different from properties of the environment. Such properties are referred to as the object's signature. The statistical properties are calculated at selected locations within the image to determine if they fall within a predetermined range of values which represents the object. If within the range, the locations are marked to indicate they are positioned within the object. A border may then be drawn around the object and the area calculated.

    摘要翻译： 根据本发明，超声图像中的物体的特征在于考虑各种体内物体参数及其在超声成像数据内的变异性。 具体来说，假设对象可以根据与环境属性一致的统计属性（或对象识别参数）来定义。 这些属性被称为对象的签名。 在图像内的选定位置处计算统计特性，以确定它们是否落入表示对象的值的预定范围内。 如果在该范围内，则标记位置以指示其位于对象内。 然后可以在对象和计算的区域周围绘制边框。

    Adaptive cancellation of ring-down artifact in IVUS imaging
    6.
    发明授权
    Adaptive cancellation of ring-down artifact in IVUS imaging 有权

    公开(公告)号：US06254543B1

    公开(公告)日：2001-07-03

    申请号：US09625149

    申请日：2000-07-25

    申请人： Sorin Grunwald ,  Tat-Jin Teo

    发明人： Sorin Grunwald ,  Tat-Jin Teo

    IPC分类号： A61B800

    CPC分类号： A61B8/00 ,  A61B8/12 ,  G01S7/52026

    摘要： In an intravascular ultrasonic (IVUS) imaging system ring-down artifact is reduced or eliminated by dynamically enhancing the ring-down over a plurality of scans, determining the ring-down range by keying on a ring-down-to-blood transition characterized by a rapid change from high amplitude to low amplitude echoes, and using a spectral pattern for a single or several A-scans within the ring-down range, using for example an FFT analysis, as the basis of selectively filtering current or subsequent images using the recently computed ring-down pattern.

    Adaptive cancellation of ring-down artifact in IVUS imaging
    7.
    发明授权
    Adaptive cancellation of ring-down artifact in IVUS imaging 有权
    IVUS成像中自动消除环形伪像

    公开(公告)号：US6102862A

    公开(公告)日：2000-08-15

    申请号：US165807

    申请日：1998-10-02

    申请人： Sorin Grunwald ,  Tat-Jin Teo

    发明人： Sorin Grunwald ,  Tat-Jin Teo

    IPC分类号： A61B8/12 ,  A61B8/00 ,  G01S7/52 ,  G01S7/524

    CPC分类号： A61B8/00 ,  G01S7/52026 ,  A61B8/12

    摘要： In an intravascular ultrasonic (IVUS) imaging system ring-down artifact is reduced or eliminated by dynamically enhancing the ring-down over a plurality of scans, determining the ring-down range by keying on a ring-down-to-blood transition characterized by a rapid change from high amplitude to low amplitude echoes, and using a spectral pattern for a single or several A-scans within the ring-down range, using for example an FFT analysis, as the basis of selectively filtering current or subsequent images using the recently computed ring-down pattern.

    摘要翻译： 在血管内超声（IVUS）成像系统中，通过在多个扫描上动态地增强衰减来减少或消除振荡衰减伪像，通过键入以下的下降到血液的转移来确定衰减范围： 从高幅度到低振幅回波的快速变化，以及使用例如FFT分析的衰减范围内的单个或多个A扫描的光谱图案作为使用该方法选择性地滤波当前或后续图像的基础 最近计算的下拉模式。

    Devices and methods for fistula-free hemodialysis
    8.
    发明公开
    Devices and methods for fistula-free hemodialysis 审中-公开

    公开(公告)号：US20240009438A1

    公开(公告)日：2024-01-11

    申请号：US18237916

    申请日：2023-08-25

    申请人： Sorin Grunwald

    发明人： Sorin Grunwald

    IPC分类号： A61M39/02

    CPC分类号： A61M39/0247 ,  A61M2039/0258 ,  A61M2039/0261

    摘要： Devices and methods for fistula-free vascular access for hemodialysis are disclosed. In exemplary embodiments, devices are provided comprising a transcutaneous access port (200) for needlelessly connecting a patient to a dialyzer, said port having different inner lumen profiles for arterial or venous blood flow and further comprising an intracorporeal conduit providing a fluid path between said transcutaneous port and a blood vessel, wherein said conduit has a distal more rigid segment attached to a device anchor (400), said device anchor having distal and proximal self-expandable segments for anastomosing said conduit to a blood vessel. An exemplary fistula-free hemodialysis method (100) provided herein consists of percutaneously deploying a first intracorporeal conduit in an artery and a second intracorporeal conduit in a vein and independently connecting each of said conduits to the arterial and venous lines of a dialyzer using said transcutaneous access ports.

    Devices and methods for endovascular electrography
    9.
    发明授权
    Devices and methods for endovascular electrography 有权
    血管内电影的装置和方法

    公开(公告)号：US09445734B2

    公开(公告)日：2016-09-20

    申请号：US12854083

    申请日：2010-08-10

    申请人： Sorin Grunwald

    发明人： Sorin Grunwald

    IPC分类号： A61N1/05 ,  A61B5/04 ,  A61B5/042 ,  A61B5/0452 ,  A61B5/06 ,  A61M25/01 ,  A61B5/00 ,  A61M25/00 ,  A61M25/09 ,  A61M39/10

    CPC分类号： A61B5/0452 ,  A61B5/04017 ,  A61B5/042 ,  A61B5/06 ,  A61B5/065 ,  A61B5/7203 ,  A61B5/726 ,  A61B5/742 ,  A61B34/20 ,  A61M25/0026 ,  A61M25/0097 ,  A61M25/0102 ,  A61M25/0147 ,  A61M25/0194 ,  A61M2025/09116 ,  A61M2039/1022 ,  A61N1/056

    摘要： An adapter for an endovascular device and a catheter steering device are provided. The adapter for an endovascular device includes a body, a conductive metal ring and a conductive wire. The body includes a first open end, a second open end, a central lumen having a substantially cylindrical surface extending from the first open end to the second open end, and a channel extending from the central lumen to an external opening. The conductive metal ring is attached to the surface of the central lumen, and the conductive wire is coupled to the conductive metal ring and extends through the channel and the external opening. The steering device for a catheter that has a plurality of lumens with spaced distal openings includes a stylet for disposition within one of the plurality of lumens, and a steering member for disposition within a different one of the plurality of lumens. In the installed position, the stylet and the steering member are connected together at respective distal ends such that a portion of the steering member is disposed outside of the distal end of the catheter.

    摘要翻译： 提供了用于血管内装置和导管转向装置的适配器。 用于血管内装置的适配器包括主体，导电金属环和导线。 主体包括第一开口端，第二开口端，具有从第一开口端延伸到第二开口端的大致圆柱形表面的中央管腔，以及从中心腔延伸到外部开口的通道。 导电金属环附接到中央腔的表面，并且导电线耦合到导电金属环并延伸穿过通道和外部开口。 用于具有间隔开的远端开口的多个腔的导管转向装置包括用于配置在所述多个腔内的一个腔内的探针以及用于配置在所述多个腔内的不同腔内的转向构件。 在安装位置，探针和转向构件在相应的远端处连接在一起，使得转向构件的一部分设置在导管远端的外侧。