公开(公告)号：US09255937B2

公开(公告)日：2016-02-09

申请号：US13809280

申请日：2011-07-20

Applicant: Yukinori Sakashita ,  Katsuaki Takahashi ,  Yoshihiro Yamashita ,  Taku Sakazume

Inventor： Yukinori Sakashita ,  Katsuaki Takahashi ,  Yoshihiro Yamashita ,  Taku Sakazume

IPC: G01N35/00 ,  G01N35/10 ,  G01N35/04

CPC classification number: G01N35/10 ,  G01N35/1002 ,  G01N35/1016 ,  G01N35/1081 ,  G01N2035/0443 ,  G01N2035/0444 ,  G01N2035/0453 ,  G01N2035/1025

Abstract: Provided is an automatic analyzer that includes a suction nozzle, a detection container, and a detector. The suction nozzle suctions a sample and a solution used for the detection of the sample. The suctioned sample and the solution are supplied to the detection container. The detector detects a signal from the sample. In addition, a vessel for the sample and a container for the solution are disposed below the detection container.

Abstract translation: 本发明提供一种包括吸嘴，检测容器和检测器的自动分析装置。 吸嘴吸取样品和用于检测样品的溶液。 将抽吸的样品和溶液供应到检测容器。 检测器检测来自样品的信号。 此外，用于样品的容器和用于溶液的容器设置在检测容器的下方。

公开(公告)号：US08017379B2

公开(公告)日：2011-09-13

申请号：US12175083

申请日：2008-07-17

Applicant: Yoshiyuki Shoji ,  Shuhei Yamamoto ,  Yoshihiro Yamashita ,  Toshinari Sakurai ,  Hiroshi Umetsu

Inventor： Yoshiyuki Shoji ,  Shuhei Yamamoto ,  Yoshihiro Yamashita ,  Toshinari Sakurai ,  Hiroshi Umetsu

IPC: C12M1/00 ,  C07H21/04 ,  G01N15/06

CPC classification number: C12N15/1006 ,  C12N15/101

Abstract: According to this invention, a nucleic acid purification instrument whereby it is possible to prevent dispersion of a mist thai causes contamination upon discharge of a solution is realized. A pressurizing nozzle is allowed to come into contact with a nucleic acid capturing column such that the sealing member is compressed. An aspiration fan is operated and thus the air in a closed channel flows toward the bottom part of a liquid receiving tank and then toward the aspiration fan as a result of a partition board. The inside of the nucleic acid capturing column is pressurized using tho pressurizing nozzle such that a solution in the nucleic acid capturing column is discharged and gravity-fed to the lower part of a liquid receiving tank. When the liquid volume m ihe nucleic acid capturing column becomes very small, the discharged solution is mixed with air so as to be formed into a mist and flows toward the aspiration fan and is captured by a protection filter so as not to bo discharged outside the closed channel.

Abstract translation: 根据本发明，实现了可以防止在溶液排出时引起污染的雾的分散的核酸纯化装置。 允许加压喷嘴与核酸捕获柱接触，使得密封构件被压缩。 吸入风扇被操作，因此封闭通道中的空气朝向液体接收罐的底部流动，然后由于隔板而朝向吸气风扇流动。 使用加压喷嘴对核酸捕集塔的内部进行加压，使得核​​酸捕获塔中的溶液被排出并重力供给到液体接收罐的下部。 当核酸捕集塔中的液体体积变得非常小时，排出的溶液与空气混合，形成为雾状并流向抽吸风扇，并被保护过滤器捕获，以便不被排出到 封闭通道。

公开(公告)号：US20090289423A1

公开(公告)日：2009-11-26

申请号：US12309078

申请日：2007-07-11

Applicant: Yasunori Sugita ,  Yoshihiro Yamashita

Inventor： Yasunori Sugita ,  Yoshihiro Yamashita

IPC: F16J15/18

CPC classification number: F16K41/046 ,  F16J15/20 ,  F16K5/0694

Abstract: A shaft seal packing exhibits high sealability at the time of initial assembly and also exhibits, even after the packing is retightened, excellent sealability by an increased seal surface pressure obtained through an effect of pressing and by self-sealability obtained through an effect of fluid pressure. A shaft seal structure for a valve includes a body for a valve, a valve shaft, a valve disc disposed within the body so as to be rotatable or capable of ascending and descending, a valve shaft seal chamber having the valve shaft axially attached thereto, a shaft seal packing that is attached to the shaft seal chamber and comprises annular packing bodies stacked and substantially V-shaped in cross section, with stacked layer faces on the inner-diameter side of the packing bodies brought into tight contact with one another and stacked layer faces on the outer-diameter side of the packing bodies formed with prescribed gaps between the adjacent stacked layer faces. In the shaft seal structure for a valve, a tightening load on the packing bodies and fluid pressure are converted to a force in the diametrical direction owing to inclined angles of stacked layer faces on the inner-diameter side to attain a seal by a surface contact between the inner peripheral surface on the inner-diameter side and the outer peripheral surface of the valve shaft on a sliding side, and a lip part on the outer-diameter side is pushed and spread owing to the gaps to attain a seal by a line contact with the shaft seal chamber on a fixed side.

Abstract translation: 轴封衬垫在初始组装时表现出高的密封性，并且即使在包装被重新密封之后也显示出通过压制效果获得的增加的密封表面压力和通过流体压力的效果获得的自密封性而具有优异的密封性 。 一种用于阀的轴密封结构，包括一阀体，一阀体，一阀体，其设置在本体内以便可转动或能够上下升降;阀轴密封室，其阀轴轴向安装在其上， 轴封衬垫，其安装在所述轴密封室上，并且包括层叠并大致V形横截面的环状填料体，所述填料体的内径侧上的堆叠层面彼此紧密接触并堆叠 在相邻的堆叠层面之间形成有规定间隙的包装体的外径侧的层面。 在阀的轴封结构中，由于内径侧的层叠面的倾斜角度，由于表面接触而形成密封，因此将包装体上的紧固负荷和流体压力转换为直径方向的力 在内径侧的内周面和滑动侧的阀轴的外周面之间，由于间隙而在外径侧的唇部被推压扩张以通过线来进行密封 在固定侧与轴封室接触。

公开(公告)号：US20090023904A1

公开(公告)日：2009-01-22

申请号：US12175083

申请日：2008-07-17

Applicant: Yoshiyuki SHOJI ,  Shuhei Yamamoto ,  Yoshihiro Yamashita ,  Toshinari Sakurai ,  Hiroshi Umetsu

Inventor： Yoshiyuki SHOJI ,  Shuhei Yamamoto ,  Yoshihiro Yamashita ,  Toshinari Sakurai ,  Hiroshi Umetsu

IPC: C07H19/00 ,  B01D15/10

CPC classification number: C12N15/1006 ,  C12N15/101

Abstract: According to this invention, a nucleic acid purification instrument whereby it is possible to prevent dispersion of a mist that causes contamination upon discharge of a solution is realized.A pressurizing nozzle 12 is allowed to come into contact with a nucleic acid capturing column 35 so as to closely adhere to the sealing member 36 in a manner such that the sealing member 36 is compressed. Then, an aspiration fan 52 is operated and thus the air in a closed channel (surrounded by a nucleic acid capturing column retention block 37 and a liquid receiving tank 54) flows toward the bottom part of a liquid receiving tank 54 and then flows toward the aspiration fan 52 as a result of installation of a partition board 55. The inside of the nucleic acid capturing column 35 is pressurized using the pressurizing nozzle 12 such that a solution in the nucleic acid capturing column 35 is discharged The discharged solution is gravity-fed to the lower part of a liquid receiving tank 54. When the liquid volume in the nucleic acid capturing column 35 becomes very small, the discharged solution is mixed with air so as to be formed into a mist. The solution exists in a mist form in the middle of an airflow formed by the aspiration fan 52 and the mist flows toward the aspiration fan 52. Then, the mist comprising the solution is captured by a protection filter 51 so as not to be discharged outside the closed channel.

Abstract translation: 根据本发明，实现了可以防止在溶液排出时引起污染的雾的分散的核酸纯化装置。 允许加压喷嘴12与核酸捕获塔35接触，以便以密封构件36被压缩的方式紧密地附着到密封构件36上。 然后，抽吸风扇52被操作，因此封闭通道中的空气（被核酸捕获柱保持块37和液体接收槽54包围）朝向液体接收罐54的底部流动，然后流向 作为分离板55的安装的吸入风扇52.使用加压喷嘴12对核酸捕集塔35的内部进行加压，使得排出的核酸捕获塔35中的溶液被排出 到液体接收罐54的下部。当核酸捕集塔35中的液体体积变得非常小时，将排出的溶液与空气混合以形成雾。 该溶液在由吸气风扇52形成的气流的中间以雾状存在，并且雾向吸入风扇52流动。然后，包含溶液的雾被保护过滤器51捕获，以便不被排出到外部 封闭通道。

公开(公告)号：US20050186607A1

公开(公告)日：2005-08-25

申请号：US11057219

申请日：2005-02-15

Applicant: Yoshiyuki Shoji ,  Toshinari Sakurai ,  Takehiko Shibasaki ,  Yoshihiro Yamashita ,  Nobutaka Kumazaki ,  Hiroshi Umetsu

Inventor： Yoshiyuki Shoji ,  Toshinari Sakurai ,  Takehiko Shibasaki ,  Yoshihiro Yamashita ,  Nobutaka Kumazaki ,  Hiroshi Umetsu

IPC: G01N1/10 ,  A61M3/00 ,  B01L3/02 ,  C12M1/00 ,  G01N1/28 ,  G01N1/34 ,  C12Q1/68 ,  A61M5/32 ,  C12M1/34

CPC classification number: G01N1/405

Abstract: It is an object of the present invention to further stabilize the efficiency of isolating nucleic acid concerning an apparatus for isolating nucleic acid. The present invention relates to an apparatus for isolating nucleic acid, the apparatus being provided with a meshed solid substance for binding nucleic acid. By employing the meshed solid substance for binding nucleic acid, fluid resistance can be reduced upon allowing a sample that includes nucleic acid to pass the solid substance for binding nucleic acid, while securing solid-phase volume that is sufficient for binding a large amount of nucleic acid. Consequently, even when the sample is allowed to pass the solid substance for binding nucleic acid at a high aspiration/dispense speed, force added to the solid substance for binding nucleic acid is small and the solid substance for binding nucleic acid is almost undistorted. The average pore size of the mesh that has an influence on the efficiency of binding nucleic acid by the meshed solid substance for binding nucleic acid is also almost unchanged. Therefore, the optimum state of the efficiency of isolating nucleic acid can be maintained.

Abstract translation: 本发明的目的是进一步稳定分离核酸分离核酸的装置的效率。 本发明涉及用于分离核酸的装置，该装置具有用于结合核酸的啮合固体物质。 通过使用网状固体物质来结合核酸，当允许包含核酸的样品通过用于结合核酸的固体物质时，可以降低流体阻力，同时确保足以结合大量核酸的固相体积 酸。 因此，即使允许样品以高抽吸/分配速度通过用于结合核酸的固体物质，加入到用于结合核酸的固体物质的力小，并且用于结合核酸的固体物质几乎没有失真。 通过用于结合核酸的网状固体物质对结合核酸的效率有影响的网的平均孔径也几乎不变。 因此，可以保持分离核酸的效率的最佳状态。

公开(公告)号：US06518535B2

公开(公告)日：2003-02-11

申请号：US09914339

申请日：2001-08-23

Applicant: Masataka Yoneya ,  Masayuki Inoue ,  Shunji Yamaguchi ,  Yoshihiro Yamashita

Inventor： Masataka Yoneya ,  Masayuki Inoue ,  Shunji Yamaguchi ,  Yoshihiro Yamashita

IPC: B23K1106

CPC classification number: B23K37/047 ,  B23K11/063 ,  B23K2101/18

Abstract: This invention relates to an apparatus and a method for manufacturing a member which makes a part of a car body of an automobile or the like by mash-seam welding a plurality of blanks. Standby areas (B) are provided at both right and left sides of an welding area (A) to/from which a seam welding machine (130) moves forward/backward, and a lapping device (100) for overlapping respective end portions of blanks (W1)(W2) and a temporary clamping device (80) for temporarily clamping the blanks (W1)(W2) are disposed on two transfer tables (70) which are sent from the standby areas (B) to the welding area (A) by turns. When the blanks (W1)(W2) with these end portions overlapped one another and temporarily clamped are sent to the welding area (A) by the transfer table (70), the blanks (W1)(W2) are permanently clamped by a permanent clamping device (180) and thereafter, subjected to a mash-seam welding by upper/lower electrode rollers (142)(148) of the seam welding machine 130. At this time, upward reactive force which acts on a cylinder (146) for pressing the upper roller (148) downwardly is received by a frame structure (134) which is installed in the welding area (A).

Abstract translation: 本发明涉及一种用于制造通过对多个坯料进行压边焊接而制成汽车等的车体的一部分的部件的装置和方法。 在焊接区域（A）的左右两侧设置备用区域（B），所述焊接区域（A）向前/向后移动缝焊机器（130），并且用于使各坯料的各个端部重叠的研磨装置 在从待机区域（B）发送到焊接区域（A）的两个传送台（70）上设置有用于临时夹持坯件（W1）（W2）的一对（W1）（W2）和临时夹紧装置（80） ）轮流。 当这些端部彼此重叠并临时夹紧的坯件（W1）（W2）通过转印台（70）被发送到焊接区域（A）时，坯件（W1）（W2）被永久地夹持 夹紧装置（180），然后通过缝焊机130的上下电极辊（142）（148）进行压缝焊接。此时，作用在气缸（146）上的向上反作用力用于 向上按压上辊148被安装在焊接区域（A）中的框架结构134接收。

公开(公告)号：US06361104B1

公开(公告)日：2002-03-26

申请号：US09874014

申请日：2001-06-06

Applicant: Ryo Tsuruo ,  Kenichi Kuriyama ,  Masaki Ohmori ,  Nobuo Ito ,  Yoshifumi Horiuchi ,  Masanobu Ohtsu ,  Hiroshi Okada ,  Yoshihiro Yamashita

Inventor： Ryo Tsuruo ,  Kenichi Kuriyama ,  Masaki Ohmori ,  Nobuo Ito ,  Yoshifumi Horiuchi ,  Masanobu Ohtsu ,  Hiroshi Okada ,  Yoshihiro Yamashita

IPC: B60J700

Abstract: A vehicle sunroof has a tilting lid provided at a front part of an opening formed in a roof of a vehicle. The tilting lid is adapted to be moved vertically at a rear end thereof with lifter mechanisms. A sliding lid is provided at a rear part of the opening supported by sliders adapted to be moved along guide rails disposed on both side edge portions of the opening and is constructed so as to be moved longitudinally through such movements of the sliders. The lifter mechanisms are provided in such a manner as to be oriented laterally at portions facing a rear end of the tilting lid on a laterally oriented cross member disposed so as to extend between front end portions of the left and right guide rails.

公开(公告)号：US06186585B1

公开(公告)日：2001-02-13

申请号：US09333029

申请日：1999-06-15

Applicant: Hiroshi Okada ,  Nobuo Ito ,  Yoshihiro Yamashita

Inventor： Hiroshi Okada ,  Nobuo Ito ,  Yoshihiro Yamashita

IPC: B60R1302

CPC classification number: B60J7/003 ,  B60J7/0038

Abstract: A vehicle sunshade device has guide rails disposed on both sides of an opening formed in a roof of a vehicle. The guide rails each has a guide groove having in turn a straight portion oriented longitudinally and extending substantially horizontally and an inclined portion continuous with the straight portion. Sliding members are slidably fitted in the groove, the sliding members being provided on sides of a sunshade for opening and closing the opening, being made larger in longitudinal length than in thickness and being elastically deformable in vertical directions. A vertical gap in the inclined portion at least at an intermediate portion thereof is made larger than a vertical gap in the straight portion of the guide groove. In the case of the vehicle sunshade device having front and rear sunshades, sliding members each having a portion for abutment at a front upper portion are provided on both sides of a rear sunshade at a front portion thereof. And side plates are provided on both sides of a front sunshade which each have at a rear end thereof an abutment portion adapted to be brought into abutment with the portion for abutment of the sliding member so as to push the rear shade rearward. An inclined portion is provided below the abutment portion in such a manner as to incline forwardly downwardly so as to push the portion for abutment of the sliding member downwardly toward the rear when the sunshade approaches the fully opened position, and a lower edge extending continuously from a front end thereof toward the front so as to prevent the upward movement of the sliding member.

Abstract translation: 车辆遮阳装置具有设置在形成于车辆顶部的开口的两侧的导轨。 导轨各自具有导向槽，该导向槽又具有纵向定向并且基本上水平延伸的直线部分和与直线部分连续的倾斜部分。 滑动构件可滑动地装配在凹槽中，滑动构件设置在遮阳板的侧面上，用于打开和关闭开口，其纵向长度大于厚度，并且在垂直方向上可弹性变形。 至少在其中间部分处的倾斜部分中的垂直间隙大于引导槽的直线部分中的垂直间隙。 在具有前后遮阳罩的车辆遮阳装置的情况下，在后部遮阳板的前部的两侧设置有在前部上部具有用于抵接的部分的滑动构件。 并且侧板设置在前遮阳板的两侧，每个侧板在其后端具有适于与滑动构件抵接的部分邻接的抵接部分，以便向后推动后遮光板。 倾斜部分设置在邻接部分下方，以便当遮阳板接近完全打开位置时向下倾斜，以便推动该部分用于使滑动构件向后朝向后方抵靠;以及下边缘从 其前端朝向前方，以防止滑动构件向上移动。

公开(公告)号：US09625273B2

公开(公告)日：2017-04-18

申请号：US13879153

申请日：2011-10-11

Applicant: Hidehiko Kuroda ,  Yoshihiro Yamashita ,  Akio Sumita

Inventor： Hidehiko Kuroda ,  Yoshihiro Yamashita ,  Akio Sumita

IPC: G01C25/00 ,  G01B17/02 ,  G01N29/30 ,  G01N29/07 ,  G01B21/04

CPC classification number: G01C25/005 ,  G01B17/02 ,  G01B21/042 ,  G01N29/07 ,  G01N29/30 ,  G01N2291/02854 ,  G01N2291/044 ,  G01N2291/102 ,  G01N2291/2634

Abstract: A thickness measurement apparatus and method to measure an object to be inspected. The thickness measurement apparatus includes: an ultrasonic wave transmission/reception device that receives/transmits an ultrasonic wave to/from a wall of a pipe to be inspected, covered with a heat insulation material; a support device that supports the ultrasonic wave transmission/reception device from an outer surface of the pipe to be inspected; a thickness calculation device that measures a propagation time of the ultrasonic wave received/transmitted by the ultrasonic wave transmission/reception device, and calculates thickness of the pipe to be inspected; a calibration board with a predetermined thickness greater than a thickness of a dead zone of the ultrasonic wave transmission/reception device; and a calibration board adjustment device that moves the calibration board toward and away from a gap between the ultrasonic wave transmission/reception device and the outer surface of the pipe to be inspected.

公开(公告)号：US09557326B2

公开(公告)日：2017-01-31

申请号：US13702175

申请日：2011-06-07

Applicant: Toru Inaba ,  Shinya Matsuoka ,  Taku Sakazume ,  Yoshihiro Yamashita ,  Masafumi Shimada ,  Osamu Kogi ,  Yushi Harada

Inventor： Toru Inaba ,  Shinya Matsuoka ,  Taku Sakazume ,  Yoshihiro Yamashita ,  Masafumi Shimada ,  Osamu Kogi ,  Yushi Harada

IPC: G01N33/543 ,  G01N33/53 ,  B03C1/033 ,  B03C1/28 ,  B03C1/01 ,  G01N33/574 ,  G01N35/00

CPC classification number: G01N33/5306 ,  B03C1/01 ,  B03C1/033 ,  B03C1/0332 ,  B03C1/288 ,  B03C2201/18 ,  B03C2201/22 ,  B03C2201/24 ,  B03C2201/26 ,  G01N33/54326 ,  G01N33/57438 ,  G01N33/57484 ,  G01N35/0098

Abstract: This invention provides a sample analyzing device and sample analyzing method designed to suppress nonuniform capture of magnetic particles (10) and detect a desired substance with higher accuracy. The sample analyzing device includes a flow channel (15) that conducts thereinto a sample which contains the magnetic particles (10), and magnetic field generating means (12) that generates magnetic fields for capturing the magnetic particles (10) in a magnetic particles capturing region of the flow channel (15); wherein the flow channel has at least one of structural characteristics that a cross-sectional area of the flow channel, at a downstream end of the magnetic particles capturing region, is larger than a cross-sectional area of the flow channel, at an upstream end of the magnetic particles capturing region, and that the magnetic fields generated by the magnetic field generating means (12) have a greater magnitude at a downstream side of the magnetic particles capturing region than at an upstream side thereof.

Abstract translation: 本发明提供了一种设计用于抑制磁性颗粒（10）的不均匀捕获并以更高精度检测所需物质的样品分析装置和样品分析方法。 样品分析装置包括：导入包含磁性粒子（10）的样品的流路（15）;以及磁场产生装置（12），其产生用于在磁性粒子捕获中捕获磁性粒子（10）的磁场 流通道（15）的区域; 其中所述流动通道具有以下结构特征中的至少一个：所述流动通道的在所述磁性粒子捕获区域的下游端处的横截面面积大于所述流动通道的横截面积，在上游端 并且由磁场产生装置（12）产生的磁场在磁性颗粒捕获区域的下游侧具有比在其上游侧更大的量值。