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公开(公告)号：US20190338233A1
公开(公告)日：2019-11-07
申请号：US16309649
申请日：2017-06-13
发明人： In Yong SEO , Seon Ho JANG , Chan KIM , Seoung Hoon LEE , Song Hee KOO
摘要： Provided is yarn for a cell culture scaffold. The yarn for a cell culture scaffold according to an exemplary embodiment of the present invention includes slitting yarn produced by cutting a compressed nanofiber web to a predetermined width. Accordingly, by creating microenvironments suitable for migration, proliferation and differentiation of cells, cell viability may be enhanced and cells may be three-dimensionally proliferated. In addition, a scaffold according to the present invention has a mechanical strength sufficient for prevention of disruption of the scaffold which occurs during cell culture, such that cells may be stably proliferated. Further, the scaffold according to the present invention uses slitting yarn formed of the compressed nanofiber web, thereby having pores with various sizes, and therefore cell proliferation and cell viability may be enhanced by creation of an extracellular matrix-like environment.
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公开(公告)号：US20170312056A1
公开(公告)日：2017-11-02
申请号：US15526544
申请日：2015-12-08
发明人： Chan KIM , Seung Hoon LEE , Song Hee KOO , Ji Hyun LEE
IPC分类号： A61C9/00 , A61L31/04 , A61L31/14 , D02G3/44 , A61L31/16 , D01F8/04 , D01D7/00 , D01D5/00 , A61C19/06 , D01D4/02 , D02G3/40
CPC分类号： A61C9/0033 , A61C19/063 , A61L31/048 , A61L31/146 , A61L31/16 , A61L2300/418 , A61L2400/12 , D01D4/02 , D01D5/0038 , D01D5/0061 , D01D5/426 , D01D7/00 , D01F6/18 , D01F8/04 , D02G3/36 , D02G3/40 , D02G3/448 , D10B2509/00 , C08L33/20
摘要： Provided is a dental cord using a nanofiber multiple yarn having a large specific surface area and a large number of three-dimensional pores, thereby effectively impregnating a drug such as a hemostatic agent, and a method of manufacturing the dental cord. The dental cord includes: a nanofiber multiple yarn which is obtained by plying and twisting at least two nanofiber tape yarns and which is impregnated with a drug, wherein the at least two nanofiber tape yarns are integrated by nanofibers made of fiber moldability polymer materials and having an average diameter of less than 1 μm, to thus be formed of a nanofiber web having three-dimensional micropores.
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公开(公告)号：US20170028431A1
公开(公告)日：2017-02-02
申请号：US15101611
申请日：2014-12-30
发明人： Song Hee KOO
CPC分类号： B05D1/02 , B05D1/18 , B05D7/22 , B05D2201/00 , B05D2252/10 , H05K5/0213
摘要： Provided are a heat insulation sheet and a method for manufacturing the same. The heat insulation sheet includes: a nonwoven fabric having a plurality of pores; and first and second coating films which are coated on both sides of the nonwoven fabric and made of a polymer material, wherein the plurality of pores are implemented as air pockets for thermal capture by the first and second coating films.
摘要翻译： 提供一种隔热片及其制造方法。 隔热片包括：具有多个孔的无纺布; 以及第一和第二涂覆膜，其被涂覆在无纺织物的两侧并由聚合物材料制成，其中多个孔被实施为气袋，用于通过第一和第二涂膜进行热捕获。
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公开(公告)号：US20220002651A1
公开(公告)日：2022-01-06
申请号：US17293993
申请日：2019-11-14
发明人： Seon Ho JANG , Hee Sung PARK , Kyung Gu HAN , Dong Sik SEO , Song Hee KOO , Ji Young KIM , Hyo Jung LEE , Su Yeon LEE , In Yong SEO , Seoung Hoon LEE , Chan KIM
IPC分类号： C12M1/12
摘要： Provided is a cell culture sheet for a large-capacity incubator. A cell culture sheet according to one embodiment of the present invention is a cell culture sheet provided in a large-capacity incubator having a plurality of sheets disposed to be spaced apart at predetermined intervals therein, wherein the cell culture sheet has an area of 100 cm2 or more and a bending depth of 0.5 cm or less. As such, even when the culture sheets are closely placed in a limited volume of space, there is little sagging or shape deformation in a specific direction to prevent the occurrence of contact with adjacent culture sheets, thereby preventing a decrease in cell culture volume due to a dead space. Furthermore, since the flow of a cell culture fluid due to the occurrence of contact can be minimized or prevented, a large capacity of cells can be stably and smoothly cultivated such that the cell culture sheet is very suitable for a large-capacity incubator and can be widely applied to the cell culture industry.
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公开(公告)号：US20230080853A1
公开(公告)日：2023-03-16
申请号：US17904339
申请日：2021-02-17
发明人： SeonHo JANG , Hee Sung PARK , Sung Il KIM , Seam MUN , Song Hee KOO , Su Yeon LEE , Ji Young KIM , In Yong SEO , Seoung Hoon LEE , Chan KIM
摘要： A method for manufacturing a fiber assembly for providing a binding surface to a bio-substance is provided. A fiber assembly for providing a binding surface to a bio-substance according to an embodiment of the present invention is manufactured by a method comprising the steps of: (1) preparing a fiber assembly in which a plurality of fibers is accumulated; and (2) performing modification to provide the fiber surface with a carboxyl group reactive to an amine group present in a bio-substance. According to the method, a bio-substance can be easily introduced at a high content into the fiber assembly. In addition, bio-substances that are conjugated therebetween and adsorbed through physical adsorption, etc. are remarkably reduced in the introduction procedure of bio-substances, whereby bio-substances can be availed with high precision and reliability in applications employing bio-substances. Furthermore, applications employing bio-substances can undergo minimal property variations attributed to the bio-substances as detachment of the bio-substances is minimized or prevented. Accordingly, the bio-substances fixed on the surface of the fiber assembly according to the present invention can find a broad spectrum of applications in various fields including the material engineering, bio engineering, medical fields, and so on.
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公开(公告)号：US20200046472A1
公开(公告)日：2020-02-13
申请号：US16658655
申请日：2019-10-21
发明人： Chan KIM , Seung Hoon LEE , Song Hee KOO , Ji Hyun LEE
IPC分类号： A61C9/00 , D02G3/44 , D02G3/40 , D01F8/04 , D01D7/00 , D01D5/00 , D01D4/02 , A61L31/14 , A61L31/04 , A61C19/06 , A61L31/16 , D02G3/36
摘要： Provided is a method of manufacturing a dental cord. The method including: producing a spinning solution by dissolving a fiber-moldable hydrophobic polymer material in a solvent; spinning the spinning solution to obtain a polymer nanofiber web composed of nanofibers and including three-dimensional micropores; laminating the polymer nanofiber web to obtain a polymer membrane; slitting the polymer membrane to obtain a nanofiber tape yarn; hydrophilic-treating the nanofiber tape yarn to obtain a hydrophilic-treated nanofiber tape yarn; plying and twisting the hydrophilic-treated nanofiber tape yarn with a covered yarn to obtain a nanofiber multiple yarn; and impregnating the nanofiber multiple yarn with a hemostatic agent.
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公开(公告)号：US20190117464A1
公开(公告)日：2019-04-25
申请号：US15559667
申请日：2016-05-19
发明人： In Yong SEO , Seung Hoon LEE , Song Hee KOO , Ji Hyun LEE
摘要： Provided is an antimicrobial dressing, which includes: a first cover member having a plurality of pores formed therein and contacting a wound; an antimicrobial membrane that is made by accumulating nanofibers containing a water-soluble polymer that is dissolved in an exudate secreted from the wound, a synthetic polymer, and an antimicrobial substance released due to dissolution of the water-soluble polymer, the antimicrobial membrane being laminated on the first cover member and having a plurality of pores formed therein; and a second cover member laminated on the antimicrobial membrane and having a plurality of pores formed therein and exposed to an external air.
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公开(公告)号：US20230190989A1
公开(公告)日：2023-06-22
申请号：US18169397
申请日：2023-02-15
发明人： In Yong SEO , Seung Hoon LEE , Song Hee KOO , Ji Hyun LEE
CPC分类号： A61L15/44 , A61L15/18 , A61L15/225 , A61L15/425 , A61L2300/104 , A61L2400/12 , A61L2300/404
摘要： Provided is an antimicrobial dressing, which includes: a first cover member having a plurality of pores formed therein and contacting a wound; an antimicrobial membrane that is made by accumulating nanofibers containing a water-soluble polymer that is dissolved in an exudate secreted from the wound, a water-insoluble polymer, and an antimicrobial substance released due to dissolution of the water-soluble polymer, the antimicrobial membrane being laminated on the first cover member and having a plurality of pores formed therein; and a second cover member laminated on the antimicrobial membrane and having a plurality of pores formed therein and exposed to an external air.
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9.发明申请公开(公告)号：US20190203178A1
公开(公告)日：2019-07-04
申请号：US16304015
申请日：2017-05-24
发明人： In Yong SEO , Seon Ho JANG , Song Hee KOO , Chan KIM , Seoung Hoon LEE
CPC分类号： C12N5/0656 , A61L27/16 , A61L27/38 , A61L27/3834 , A61L27/44 , C12N5/00 , C12N2533/30 , D02G1/02 , D02G1/0206 , D02G1/0286 , D02G1/0293 , D02G3/02 , D02G3/26 , D02G3/44 , D02G3/448 , D03D15/00 , D10B2201/02 , D10B2321/042 , D10B2331/02 , D10B2331/04 , D10B2509/00
摘要： A yarn including a plurality of twists formed by twisting single fiber strand or multiple fiber strands; and fiber grooves, which are spaces formed between the twists, to provide three-dimensional growth spaces and migration paths for cells. Accordingly, a cell proliferation rate and cell viability may be enhanced by creating microenvironments suitable for migration, proliferation and differentiation of cultured cells. In addition, cell clusters having more uniform shapes may be easily implemented by forming the proliferation spaces and migration paths for the cultured cells as similar as possible to each other in each scaffold. Further, the cells cultured thereby can be cultured in a suitable shape and structure to be applied to an in vitro experimental model or transplanted into the body of an animal, and can be widely applied in various products used in a cell culture or tissue engineering field.
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