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    FLUID INJECTION
    5.
    发明申请
    FLUID INJECTION 有权
    流体注射

    公开(公告)号：US20120132288A1

    公开(公告)日：2012-05-31

    申请号：US13379782

    申请日：2010-06-25

    申请人： David A. Weitz ,  Adam R. Abate ,  Tony Hung ,  Pascaline Mary

    发明人： David A. Weitz ,  Adam R. Abate ,  Tony Hung ,  Pascaline Mary

    IPC分类号： F15C1/00

    CPC分类号： B01F5/0471 ,  B01F13/0071 ,  B01F13/0076 ,  B01J19/0093 ,  B01J2219/00837 ,  B01J2219/00853 ,  B01J2219/00862 ,  B01J2219/00889 ,  B01L3/50273 ,  B01L3/502784 ,  B01L2300/0867 ,  B01L2400/0415 ,  F16K99/0042 ,  F16K99/0051 ,  G01N27/44791 ,  G01N2035/1034 ,  Y10T137/0391 ,  Y10T137/206

    摘要： The present invention generally relates to systems and methods for the control of fluids and, in some cases, to systems and methods for flowing a fluid into and/or out of other fluids. As examples, fluid may be injected into a droplet contained within a fluidic channel, or a fluid may be injected into a fluidic channel to create a droplet. In some embodiments, electrodes may be used to apply an electric field to one or more fluidic channels, e.g., proximate an intersection of at least two fluidic channels. For instance, a first fluid may be urged into and/or out of a second fluid, facilitated by the electric field. The electric field, in some cases, may disrupt an interface between a first fluid and at least one other fluid. Properties such as the volume, flow rate, etc. of a first fluid being urged into and/or out of a second fluid can be controlled by controlling various properties of the fluid and/or a fluidic droplet, for example curvature of the fluidic droplet, and/or controlling the applied electric field.

    摘要翻译： 本发明一般涉及用于控制流体的系统和方法，并且在一些情况下涉及将流体流入和/或流出其它流体的系统和方法。 作为示例，流体可以被注入到包含在流体通道内的液滴中，或者可以将流体注入到流体通道中以产生液滴。 在一些实施例中，可以使用电极将电场施加到一个或多个流体通道，例如至少两个流体通道的相交处。 例如，可以通过电场促进第一流体进入和/或流出第二流体。 在一些情况下，电场可能破坏第一流体和至少一种其它流体之间的界面。 可以通过控制流体和/或流体液滴的各种性质（例如流体液滴的曲率）来控制被推入和/或流出第二流体的第一流体的体积，流速等的性质 ，和/或控制所施加的电场。

    MICROFLUIDIC DEVICE FOR PRODUCTION AND COLLECTION OF DROPLETS OF A FLUID
    8.
    发明申请
    MICROFLUIDIC DEVICE FOR PRODUCTION AND COLLECTION OF DROPLETS OF A FLUID 审中-公开
    用于生产和收集流体液滴的微流体装置

    公开(公告)号：US20130236901A1

    公开(公告)日：2013-09-12

    申请号：US13876960

    申请日：2011-10-03

    申请人： Marie-Claude Potier ,  Patrick Tabeling ,  Luce Dauphinot ,  Nadege Bois ,  Fabrice Monti ,  Pascaline Mary

    发明人： Marie-Claude Potier ,  Patrick Tabeling ,  Luce Dauphinot ,  Nadege Bois ,  Fabrice Monti ,  Pascaline Mary

    IPC分类号： C12Q1/68

    摘要： A microfluidic device and method for producing and collecting single droplets of a first fluid, the device including a microfluidic platform having at least a droplet microchannel wherein is produced a flow of single droplets of the first fluid dispersed in a second fluid immiscible with the first fluid, the droplet microchannel having at least one inlet extremity and at least one outlet extremity for distributing the flow of droplets, the device further including: a collection device including a plurality of receiving areas adapted to collect at least one of the droplets, elements for changing the relative position of the collection device and the outlet of the microfluidic platform, elements for controlling the flow of droplets, and elements for synchronizing the flow of droplets at the outlet of the droplet microchannel and the relative movement of the collection device with regards to the microfluidic platform.

    摘要翻译： 一种用于产生和收集第一流体的单液滴的微流体装置和方法，该装置包括具有至少液滴微通道的微流体平台，其中产生分散在与第一流体不混溶的第二流体中的第一流体的单液滴流 所述液滴微通道具有至少一个入口末端和用于分配液滴流的至少一个出口末端，所述装置还包括：收集装置，其包括适于收集液滴中的至少一个的多个接收区域，用于改变 微流体平台的收集装置和出口的相对位置，用于控制液滴流动的元件和用于使液滴微通道出口处的液滴流动同步的元件以及收集装置相对于液滴微通道的相对运动 微流体平台。

    Nucleic acid target detection using a detector, a probe and an inhibitor
    9.
    发明授权
    Nucleic acid target detection using a detector, a probe and an inhibitor 有权
    使用检测器，探针和抑制剂进行核酸靶检测

    公开(公告)号：US09581549B2

    公开(公告)日：2017-02-28

    申请号：US13992187

    申请日：2011-12-07

    申请人： Tal Raz ,  Pascaline Mary

    发明人： Tal Raz ,  Pascaline Mary

    IPC分类号： C12Q1/68 ,  C12P19/34 ,  G01N21/64

    CPC分类号： G01N21/6486 ,  C12Q1/6818 ,  C12Q1/6858 ,  C12Q2535/125 ,  C12Q2565/101 ,  C12Q2563/159 ,  C12Q2565/629

    摘要： The present invention generally pertains to methods for detecting the presence or absence of a particular nucleic acid sequence. The present invention generally relates to incorporating a detector into a target nucleic acid, adding an oligonucleotide probe, polymerase enzyme and an inhibitor to the reaction, and detecting interference of the oligonucleotide probe with the inhibitor as an indication of the presence of a particular target nucleic acid sequence as well as kits encompassing the same.

    摘要翻译： 本发明一般涉及检测特定核酸序列的存在或不存在的方法。 本发明一般涉及将检测器结合到靶核酸中，向反应中加入寡核苷酸探针，聚合酶和抑制剂，以及检测寡核苷酸探针与抑制剂的干扰作为特定靶核酸的存在的指示 酸序列以及包含其的试剂盒。