利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

82 条记录 (耗时 0.035 秒)

    Systems and methods for providing neural stimulation transitions
    2.
    发明授权
    Systems and methods for providing neural stimulation transitions 有权
    用于提供神经刺激过渡的系统和方法

    公开(公告)号：US08630716B2

    公开(公告)日：2014-01-14

    申请号：US13587654

    申请日：2012-08-16

    申请人： Marina V. Brockway ,  Paul A. Haefner ,  Anthony V. Caparso ,  Wondimeneh Tesfayesus

    发明人： Marina V. Brockway ,  Paul A. Haefner ,  Anthony V. Caparso ,  Wondimeneh Tesfayesus

    IPC分类号： A61N1/00

    CPC分类号： A61N1/36114 ,  A61N1/36117

    摘要： A method embodiment comprises generating a neural stimulation signal for a neural stimulation therapy. The signal is generated during a duty cycle of a stimulation period to provide the neural stimulation therapy with an intensity at a therapy level for a portion of the duty cycle. In various embodiments, a ramp up protocol is implemented to begin the duty cycle, a ramp down protocol is implemented to end the duty cycle, or both the ramp up protocol and the ramp down protocol are implemented. The ramp up protocol includes ramping up the intensity from a non-zero first subthreshold level for the neural stimulation therapy at the beginning of the duty cycle to the therapy level. The ramp down protocol includes ramping down the intensity from the therapy intensity level to a non-zero second subthreshold level for the neural stimulation therapy at the end of the duty cycle.

    摘要翻译： 方法实施例包括产生用于神经刺激治疗的神经刺激信号。 在刺激期的占空比期间产生信号，以在占空比的一部分的治疗水平上提供具有强度的神经刺激治疗。 在各种实施例中，实现斜坡上升协议以开始占空比，实现斜降协议以结束占空比，或者实现了升温协议和斜降协议两者。 加速协议包括在占空比开始时到神经刺激治疗的非零第一亚阈值水平上升到治疗水平。 斜坡协议包括在占空比结束时将神经刺激治疗的强度从治疗强度水平向下降至非零秒次阈值水平。

    Systems and methods for producing asynchronous neural responses to treat pain and/or other patient conditions
    3.
    发明授权
    Systems and methods for producing asynchronous neural responses to treat pain and/or other patient conditions 有权
    用于产生用于治疗疼痛和/或其他患者病症的异步神经反应的系统和方法

    公开(公告)号：US08509906B2

    公开(公告)日：2013-08-13

    申请号：US13544727

    申请日：2012-07-09

    申请人： Andre B. Walker ,  Zi-Ping Fang ,  Anthony V. Caparso

    发明人： Andre B. Walker ,  Zi-Ping Fang ,  Anthony V. Caparso

    IPC分类号： A61N1/00

    CPC分类号： A61N1/36171 ,  A61N1/0551 ,  A61N1/36071 ,  A61N1/37247

    摘要： Systems and methods for producing asynchronous neural responses to treat pain and/or other patient conditions are disclosed. A method in accordance with a particular embodiment includes selecting a target stimulation frequency that is above a threshold frequency, with the threshold frequency corresponding to a refractory period for neurons of a target sensory neural population. The method can further include producing a patient sensation of paresthesia by directing an electrical signal to multiple sensory neurons of the target sensory neural population at the stimulation frequency, with individual neurons of the sensory neural population completing corresponding individual refractory periods at different times, resulting in an asynchronous sensory neuron response to the electrical signal.

    摘要翻译： 公开了用于产生用于治疗疼痛和/或其他患者状况的异步神经反应的系统和方法。 根据特定实施例的方法包括选择阈值频率以上的目标刺激频率，阈值频率对应于目标感觉神经群体的神经元的不应期。 该方法可以进一步包括通过在刺激频率下将电信号引导到目标感觉神经群体的多个感觉神经元来产生感觉异常感觉，感觉神经群体的个体神经元在不同时间完成相应的单个不应期，导致 对电信号的异步感觉神经元响应。

    System and method for neural stimulation
    5.
    发明授权
    System and method for neural stimulation 有权

    公开(公告)号：US08457734B2

    公开(公告)日：2013-06-04

    申请号：US11468135

    申请日：2006-08-29

    申请人： Imad Libbus ,  Andrew P. Kramer ,  Anthony V. Caparso ,  Kristofer J. James ,  Stephen Ruble ,  Weiying Zhao

    发明人： Imad Libbus ,  Andrew P. Kramer ,  Anthony V. Caparso ,  Kristofer J. James ,  Stephen Ruble ,  Weiying Zhao

    IPC分类号： A61N1/365

    CPC分类号： A61N1/365 ,  A61N1/36053 ,  A61N1/36114

    摘要： Various aspects provide an implantable device. In various embodiments, the device comprises at least one port, where each port is adapted to connect a lead with an electrode to the device. The device further includes a stimulation platform, including a sensing circuit connected to the at least one port to sense an intrinsic cardiac signal and a stimulation circuit connected to the at least one port via a stimulation channel to deliver a stimulation signal through the stimulation channel to the electrode. The stimulation circuit is adapted to deliver stimulation signals through the stimulation channel for both neural stimulation therapy and CRM therapy. The sensing and stimulation circuits are adapted to perform CRM functions. The device further includes a controller connected to the sensing circuit and the stimulation circuit to control the neural stimulation therapy and the CRM therapy. Other aspects and embodiments are provided herein.

    Implantable and rechargeable neural stimulator
    7.
    发明授权
    Implantable and rechargeable neural stimulator 有权
    可植入和可充电的神经刺激器

    公开(公告)号：US08126561B2

    公开(公告)日：2012-02-28

    申请号：US12613094

    申请日：2009-11-05

    申请人： Abhi V. Chavan ,  Anthony V. Caparso ,  Avram Scheiner

    发明人： Abhi V. Chavan ,  Anthony V. Caparso ,  Avram Scheiner

    IPC分类号： A61N1/00

    CPC分类号： A61N1/36117 ,  A61N1/3605 ,  A61N1/36071 ,  A61N1/36135 ,  A61N1/37205 ,  A61N1/37217 ,  A61N1/37288 ,  A61N1/3787

    摘要： One aspect of the present subject matter relates to an implantable medical device. An embodiment of the device comprises a rechargeable power supply adapted to be recharged through an ultrasound signal, a neural stimulator connected to the rechargeable power supply, and a controller connected to the rechargeable power supply. The neural stimulator is adapted to generate a neural stimulation signal for delivery to a neural stimulation target through an electrode. The controller is further connected to the neural stimulator to control the neural stimulator according to a neural stimulation protocol. Other aspects are provided herein.

    摘要翻译： 本主题的一个方面涉及可植入医疗装置。 该装置的实施例包括适于通过超声信号再充电的可再充电电源，连接到可再充电电源的神经刺激器和连接到可再充电电源的控制器。 神经刺激器适于产生用于通过电极递送到神经刺激靶的神经刺激信号。 控制器进一步连接到神经刺激器，以根据神经刺激方案来控制神经刺激器。 本文提供了其他方面。

    High frequency stimulation for treatment of atrial fibrillation
    8.
    发明授权
    High frequency stimulation for treatment of atrial fibrillation 失效
    高频刺激治疗房颤

    公开(公告)号：US07937147B2

    公开(公告)日：2011-05-03

    申请号：US11680322

    申请日：2007-02-28

    申请人： Haris Sih ,  Mark Schwartz ,  Anthony V. Caparso

    发明人： Haris Sih ,  Mark Schwartz ,  Anthony V. Caparso

    IPC分类号： A61N1/36

    CPC分类号： A61N1/0556 ,  A61N1/05 ,  A61N1/0587 ,  A61N1/36114 ,  A61N1/3621 ,  A61N1/3624 ,  A61N1/395 ,  A61N1/3962

    摘要： The invention relates to methods and devices for treating and/or preventing atrial fibrillation. In an embodiment, the invention includes a method of treating and/or preventing atrial fibrillation including applying an oscillating electrical stimulus to a tissue of a patient, the oscillating electrical stimulus sufficient to block transmission of electrical signals through the tissue. In an embodiment, the invention includes an implantable medical device including a stimulator configured to generate an oscillating electrical stimulus at a frequency and amplitude sufficient to block transmission of electrical signals through a tissue, a stimulation electrode in communication with the stimulator, the stimulation electrode configured to deliver the oscillating electrical stimulus to the tissue, and control circuitry in communication with the stimulator, the control circuitry configured to selectively deliver the oscillating electrical stimulus to treat and/or prevent atrial fibrillation. Other embodiments are also described herein.

    摘要翻译： 本发明涉及用于治疗和/或预防房颤的方法和装置。 在一个实施方案中，本发明包括治疗和/或预防房颤的方法，包括将振荡电刺激施加到患者的组织，所述振荡电刺激足以阻止电信号通过组织传播。 在一个实施例中，本发明包括可植入医疗装置，其包括刺激器，所述刺激器被配置为产生振荡电刺激，其频率和幅度足以阻止通过组织的电信号的传输，与所述刺激器通信的刺激电极， 将振荡电刺激递送到组织，以及与刺激器通信的控制电路，所述控制电路被配置为选择性地递送振荡电刺激以治疗和/或预防房颤。 本文还描述了其它实施例。

    TRANSCUTANEOUS NEUROSTIMULATOR FOR TREATING HYPERTENSION
    9.
    发明申请
    TRANSCUTANEOUS NEUROSTIMULATOR FOR TREATING HYPERTENSION 有权
    TRANSCUTANEOUS神经细胞治疗高血压

    公开(公告)号：US20110082515A1

    公开(公告)日：2011-04-07

    申请号：US12969023

    申请日：2010-12-15

    申请人： Imad Libbus ,  Anthony V. Caparso ,  Andrew P. Kramer

    发明人： Imad Libbus ,  Anthony V. Caparso ,  Andrew P. Kramer

    IPC分类号： A61N1/36

    CPC分类号： A61N1/36114 ,  A61N1/36017 ,  Y10S128/907

    摘要： A neurostimulation device includes an external neurostimulator worn by a patient using a bracing element that braces a portion of the patient's body. The external neurostimulator delivers neurostimulation to modulate a cardiovascular function of the patient. In one embodiment, the external stimulator delivers the neurostimulation transcutaneously to a stimulation target in the patient's body using surface stimulation electrodes placed on the body approximately over the stimulation target.

    摘要翻译： 神经刺激装置包括由患者佩戴的外部神经刺激器，其使用支撑患者身体的一部分的支撑元件。 外部神经刺激仪提供神经刺激来调节患者的心血管功能。 在一个实施例中，外部刺激器将神经刺激经皮递送到患者身体中的刺激目标，其中使用位于身体上的表面刺激电极大致超过刺激目标。