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公开(公告)号：US20070225218A1
公开(公告)日：2007-09-27
申请号：US10481700
申请日：2002-06-26
申请人： Angelo Delegeane , Mark Borowsky , Farrah Khan , Liam Kearney , Jayalaxmi Ramkumar , Narinder Chawla , Yan Lu , Cynthia Honchell , Deborah kallick , Brooke Emerling , Ann Gorvard , Jennifer Griffin , Bridget Warren , Henry Yue , Kavitha Thangavelu , William Sprague , Craig Ison , Vicki Elliott , Patricia Lehr-Mason , Thomas Richardson , Uyen Tran , Anita Swarnakar , Pei Jin , Amy Kable
发明人： Angelo Delegeane , Mark Borowsky , Farrah Khan , Liam Kearney , Jayalaxmi Ramkumar , Narinder Chawla , Yan Lu , Cynthia Honchell , Deborah kallick , Brooke Emerling , Ann Gorvard , Jennifer Griffin , Bridget Warren , Henry Yue , Kavitha Thangavelu , William Sprague , Craig Ison , Vicki Elliott , Patricia Lehr-Mason , Thomas Richardson , Uyen Tran , Anita Swarnakar , Pei Jin , Amy Kable
IPC分类号： C12P21/00 , A61K38/00 , C07H21/04 , C07K14/00 , C12Q1/68 , G01N33/53 , C07K16/18 , C12N15/00 , C12N5/06
摘要： Various embodiments of the invention provide human extracellular messengers (EXMES) and polynucleotides which identify and encode EXMES. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of EXMES.
摘要翻译： 本发明的各种实施方案提供了识别和编码EXMES的人细胞外信使（EXMES）和多核苷酸。 本发明的实施方案还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 其它实施方案提供用于诊断，治疗或预防与异常表达EXMES相关的紊乱的方法。
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公开(公告)号：US20050239126A1
公开(公告)日：2005-10-27
申请号：US11167040
申请日：2005-06-27
申请人： Stephen Todd , Angelo Delegeane , Ameena Gandhi , Danniel Nguyen , April Hafalia , Liam Kearney , Yan Lu , Ernestine Lee , Narinder Chawla , Debopriya Das , Chandra Arvizu , Monique Yao , Deborah Kallick , Vicki Elliott , Li Ding , Henry Yue , Roopa Reddy , Dyung Lu , Jayalaxmi Ramkumar , Junming Yang , Catherine Tribouley , Neil Burford , Mariah Baughn , Preeti Lal , Mark Borowsky , Farrah Khan , Rajagopal Gururajan , Y. Tang , Janice Au-Young , Bridget Warren , Roberto Hernandez , Brendan Duggan
发明人： Stephen Todd , Angelo Delegeane , Ameena Gandhi , Danniel Nguyen , April Hafalia , Liam Kearney , Yan Lu , Ernestine Lee , Narinder Chawla , Debopriya Das , Chandra Arvizu , Monique Yao , Deborah Kallick , Vicki Elliott , Li Ding , Henry Yue , Roopa Reddy , Dyung Lu , Jayalaxmi Ramkumar , Junming Yang , Catherine Tribouley , Neil Burford , Mariah Baughn , Preeti Lal , Mark Borowsky , Farrah Khan , Rajagopal Gururajan , Y. Tang , Janice Au-Young , Bridget Warren , Roberto Hernandez , Brendan Duggan
CPC分类号： C12N9/6421 , A01K2217/05 , A01K2217/075 , C07H21/04 , C12N9/6472 , C12Q1/6837 , C12Q1/6883 , C12Q2600/156 , C12Q2600/158 , Y02A50/52
摘要： The invention provides human proteases (PRTS) and polynucleotides which identify and encode PRTS. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PRTS.
摘要翻译： 本发明提供鉴定和编码PRTS的人类蛋白酶（PRTS）和多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供诊断，治疗或预防与PRTS异常表达相关的疾病的方法。
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公开(公告)号：US20050227280A1
公开(公告)日：2005-10-13
申请号：US11140224
申请日：2005-05-31
申请人： Angelo Delegeane , Preeti Lal , April Hafalia , Chandra Arvizu , Narinder Chawla , Liam Kearney , Catherine Tribouley , Farrah Khan , Monique Yao , Mariah Baughn , Yalda Azimzai , Vicki Elliott , Danniel Nguyen , Ameena Gandhi , Junming Yang , Roberto Hernandez , Jennifer Policky , Dyung Aina Lu , Roopa Reddy , Henry Yue , Y. Tang
发明人： Angelo Delegeane , Preeti Lal , April Hafalia , Chandra Arvizu , Narinder Chawla , Liam Kearney , Catherine Tribouley , Farrah Khan , Monique Yao , Mariah Baughn , Yalda Azimzai , Vicki Elliott , Danniel Nguyen , Ameena Gandhi , Junming Yang , Roberto Hernandez , Jennifer Policky , Dyung Aina Lu , Roopa Reddy , Henry Yue , Y. Tang
IPC分类号： G01N33/50 , A61K38/00 , A61K45/00 , A61P1/00 , A61P1/10 , A61P1/16 , A61P3/10 , A61P7/02 , A61P9/00 , A61P9/10 , A61P9/12 , A61P11/00 , A61P13/12 , A61P15/00 , A61P17/00 , A61P17/06 , A61P19/10 , A61P21/04 , A61P25/00 , A61P29/00 , A61P31/04 , A61P31/10 , A61P31/12 , A61P31/18 , A61P33/00 , A61P35/00 , A61P37/06 , C07H21/04 , C07K16/40 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/48 , C12N9/64 , C12N15/09 , C12N15/55 , C12P21/08 , C12Q1/02 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N33/566
CPC分类号： C12N9/6421 , A61K38/00 , C07H21/04 , C12N9/48
摘要： The invention provides human proteases (PRTS) and polynucleotides which identify and encode PRTS. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PRTS.
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公开(公告)号：US07112426B2
公开(公告)日：2006-09-26
申请号：US10288798
申请日：2002-11-01
申请人： Olga Bandman , Danniel B Nguyen , Narinder K Chawla , April J A Hafalia , Monique G Yao , Ameena R Gandhi , Rajagopal Gururajan , Li Ding , Chandra S Arvizu , Henry Yue , Mariah R Baughn , Catherine M Tribouley , Michael B Thornton , Vicki S Elliott , Yan Lu , Craig H Ison , Janice K Au-Young , Y Tom Tang , Yalda Azimzai , John D Burrill , Gregory A Marcus , Kurt A Zingler , Dyung Aina M Lu , Preeti G Lai , Jayalaxmi Ramkumar , Bridget A Warren , Liam Kearney , Jennifer L Policky , Kavitha Thangavelu , Neil Burford
发明人： Olga Bandman , Danniel B Nguyen , Narinder K Chawla , April J A Hafalia , Monique G Yao , Ameena R Gandhi , Rajagopal Gururajan , Li Ding , Chandra S Arvizu , Henry Yue , Mariah R Baughn , Catherine M Tribouley , Michael B Thornton , Vicki S Elliott , Yan Lu , Craig H Ison , Janice K Au-Young , Y Tom Tang , Yalda Azimzai , John D Burrill , Gregory A Marcus , Kurt A Zingler , Dyung Aina M Lu , Preeti G Lai , Jayalaxmi Ramkumar , Bridget A Warren , Liam Kearney , Jennifer L Policky , Kavitha Thangavelu , Neil Burford
CPC分类号： C07K14/4702 , A01K2217/05
摘要： The invention provides human human kinases (PKIN) and polynucleotides which identify and encode PKIN. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PKIN.
摘要翻译： 本发明提供人类人类激酶（PKIN）和识别和编码PKIN的多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂。 本发明还提供用于诊断，治疗或预防与PKIN的异常表达相关的障碍的方法。
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公开(公告)号：US06927056B2
公开(公告)日：2005-08-09
申请号：US10363937
申请日：2001-09-06
申请人： Stephen Todd , Angelo M. Delegeane , Ameena R. Gandhi , Danniel B. Nguyen , April J. A. Hafalia , Liam Kearney , Yan Lu , Ernestine A. Lee , Narinder K. Chawla , Debopriya Das , Chandra S. Arvizu , Monique G. Yao , Deborah A. Kallick , Vicki S. Elliott , Li Ding , Henry Yue , Roopa M. Reddy , Dyung Aina M. Lu , Jayalaxmi Ramkumar , Junming Yang , Catherine M. Tribouley , Neil Burford , Mariah R. Baughn , Preeti G. Lal , Mark L. Borowsky , Farrah A. Khan , Rajagopal Gururajan , Y. Tom Tang , Janice K. Au-Young , Bridget A. Warren , Roberto Hernandez , Brendan M. Duggan
发明人： Stephen Todd , Angelo M. Delegeane , Ameena R. Gandhi , Danniel B. Nguyen , April J. A. Hafalia , Liam Kearney , Yan Lu , Ernestine A. Lee , Narinder K. Chawla , Debopriya Das , Chandra S. Arvizu , Monique G. Yao , Deborah A. Kallick , Vicki S. Elliott , Li Ding , Henry Yue , Roopa M. Reddy , Dyung Aina M. Lu , Jayalaxmi Ramkumar , Junming Yang , Catherine M. Tribouley , Neil Burford , Mariah R. Baughn , Preeti G. Lal , Mark L. Borowsky , Farrah A. Khan , Rajagopal Gururajan , Y. Tom Tang , Janice K. Au-Young , Bridget A. Warren , Roberto Hernandez , Brendan M. Duggan
IPC分类号： A01K67/00 , C07H21/04 , C12N9/64 , C12N15/09 , C12P21/06 , C12Q1/68 , C12N1/20 , C12N15/00 , C12N15/63
CPC分类号： C12N9/6421 , A01K2217/05 , A01K2217/075 , C07H21/04 , C12N9/6472 , C12Q1/6837 , C12Q1/6883 , C12Q2600/156 , C12Q2600/158 , Y02A50/52
摘要： The invention provides a human cysteine proteases and polynucleotides which encode those proteases. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists, as well as methods for diagnosing, treating, or preventing disorders associated with aberrant expression of cysteine proteases.
摘要翻译： 本发明提供编码这些蛋白酶的人半胱氨酸蛋白酶和多核苷酸。 本发明还提供表达载体，宿主细胞，抗体，激动剂和拮抗剂，以及用于诊断，治疗或预防与半胱氨酸蛋白酶异常表达相关的紊乱的方法。
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