公开(公告)号：US20110004027A1

公开(公告)日：2011-01-06

申请号：US12595430

申请日：2008-04-11

申请人： Anil J. Mehta ,  Danil Tirtowidjojo ,  Bruce D. Hook ,  John R. Briggs ,  Jeffrey G. Hippler

发明人： Anil J. Mehta ,  Danil Tirtowidjojo ,  Bruce D. Hook ,  John R. Briggs ,  Jeffrey G. Hippler

IPC分类号： C07C31/36 ,  B01J19/00

CPC分类号： C07C29/62 ,  C07C31/42 ,  C07C31/36

摘要： A process and apparatus for producing chlorohydrin comprising reacting a multihydroxylated-aliphatic hydrocarbon-containing stream with a stream of a first effluent exiting from a hydrochlorination reactor in at least one vessel wherein the vessel exhibits a plug flow residence time characteristic, under conditions such that at least a portion of any unreacted HCl component present in the first effluent is reacted with the multihydroxylated-aliphatic hydrocarbon present in the multihydroxylated aliphatic hydrogen-containing stream to from an amount of monochlorohydrin in a stream of a second effluent exiting from the plug flow vessel; recovering said second effluent; and then optionally using the second effluent from the plug flow reactor in a subsequent processing operation.

摘要翻译： 一种用于生产氯代醇的方法和装置，包括使多羟基化 - 脂族含烃流与在至少一个容器中从氢氯化反应器排出的第一流出物流反应，其中容器呈现塞流动停留时间特性， 存在于第一流出物中的任何未反应的HCl组分的至少一部分与存在于多羟基化脂族含氢物流中的多羟基化脂族烃与从活塞流容器排出的第二流出物流中的一氯代醇反应; 回收所述第二流出物; 然后在随后的处理操作中任选地使用来自活塞流反应器的第二流出物。

公开(公告)号：US08541632B2

公开(公告)日：2013-09-24

申请号：US12595430

申请日：2008-04-11

申请人： Anil J. Mehta ,  Danil Tirtowidjojo ,  Bruce D. Hook ,  John R. Briggs ,  Jeffrey G. Hippler

发明人： Anil J. Mehta ,  Danil Tirtowidjojo ,  Bruce D. Hook ,  John R. Briggs ,  Jeffrey G. Hippler

IPC分类号： C07C311/36

CPC分类号： C07C29/62 ,  C07C31/42 ,  C07C31/36

摘要： A process and apparatus for producing chlorohydrin comprising reacting a multihydroxylated-aliphatic hydrocarbon-containing stream with a stream of a first effluent exiting from a hydrochlorination reactor in at least one vessel wherein the vessel exhibits a plug flow residence time characteristic, under conditions such that at least a portion of any unreacted HCl component present in the first effluent is reacted with the multihydroxylated-aliphatic hydrocarbon present in the multihydroxylated aliphatic hydrogen-containing stream to from an amount of monochlorohydrin in a stream of a second effluent exiting from the plug flow vessel; recovering said second effluent; and then optionally using the second effluent from the plug flow reactor in a subsequent processing operation.

摘要翻译： 一种用于生产氯代醇的方法和装置，包括使多羟基化 - 脂族含烃流与在至少一个容器中从氢氯化反应器排出的第一流出物流反应，其中容器呈现塞流动停留时间特性， 存在于第一流出物中的任何未反应的HCl组分的至少一部分与存在于多羟基化脂族含氢物流中的多羟基化脂族烃与从活塞流容器排出的第二流出物流中的一氯代醇反应; 回收所述第二流出物; 然后在随后的处理操作中任选地使用来自活塞流反应器的第二流出物。

公开(公告)号：US08088957B2

公开(公告)日：2012-01-03

申请号：US11628269

申请日：2005-07-18

申请人： William J. Kruper, Jr. ,  David J. Schreck ,  Kenneth L. Kearns ,  Richard D. Varjian ,  Mark E. Jones ,  Robert M. Campbell ,  Bruce D. Hook ,  John R. Briggs ,  Jeffrey G. Hippler

发明人： William J. Kruper, Jr. ,  David J. Schreck ,  Kenneth L. Kearns ,  Richard D. Varjian ,  Mark E. Jones ,  Robert M. Campbell ,  Bruce D. Hook ,  John R. Briggs ,  Jeffrey G. Hippler

IPC分类号： C07C31/34

CPC分类号： C07D301/24 ,  C07C29/62 ,  C07C29/82 ,  C07C31/36 ,  C07C31/42

摘要： The present invention relates to a process for converting a multihydroxylated-aliphatic hydrocarbon or ester thereof to a chlorohydrin, by contacting the multihydroxylated-aliphatic hydrocarbon or ester thereof starting material with a source of a superatmospheric partial pressure of hydrogen chloride for a sufficient time and at a sufficient temperature, and wherein such contracting step is carried out without substantial removal of water, to produce the desired chlorohydrin product; wherein the desired product or products can be made in high yield without substantial formation of undesired overchlorinated byproducts. In addition, certain catalysts of the present invention may be used in the present process at superatmospheric, atmospheric and subatmospheric pressure conditions with improved results.

摘要翻译： 本发明涉及将多羟基化脂肪族烃或其酯转化为氯代醇的方法，该方法是将多羟基化脂族烃或其起始原料与氯化氢的超大气压分压源接触足够的时间和 足够的温度，并且其中这种收缩步骤在不显着除去水的情况下进行，以产生所需的氯代醇产物; 其中所需的产物或产物可以高产率制备而不显着形成不需要的过氯化副产物。 此外，本发明的某些催化剂可以在超大气压，大气压和低于大气压的条件下用于本方法，并具有改进的结果。

公开(公告)号：US20110028766A1

公开(公告)日：2011-02-03

申请号：US12935719

申请日：2009-03-18

申请人： John R. Briggs ,  Bruce D. Hook ,  William J. Kruper Jr. ,  Anil Mehta ,  Robert M. Alvarado ,  Sascha Noormann ,  Perry S. Basile

发明人： John R. Briggs ,  Bruce D. Hook ,  William J. Kruper Jr. ,  Anil Mehta ,  Robert M. Alvarado ,  Sascha Noormann ,  Perry S. Basile

IPC分类号： C07C31/34 ,  B01J19/00

CPC分类号： C07C29/62 ,  C07C31/42 ,  C07C31/36

摘要： The present invention relates to a process for converting at least one multihydroxylated-aliphatic hydrocarbon and/or an ester thereof to at least one chlorohydrin and/or an ester thereof, comprising at least one reaction step in which the multihydroxylated-aliphatic hydrocarbon and/or ester thereof is contacted with hydrogen chloride under reaction conditions to produce the chlorohydrin and/or ester thereof, followed by at least one downstream processing step in which the effluents of the reaction step are processed, wherein the downstream processing step is performed in such conditions that the effluents containing the chlorohydrin and/or ester thereof are kept at a temperature of less than 120° C. The invention allows to minimize the liberation of hydrogen chloride from the products of the hydrochlorination reaction, hence reducing the corrosion of the downstream equipment and reducing the need to use costly corrosion resistant materials.

摘要翻译： 本发明涉及将至少一种多羟基化脂族烃和/或其酯转化为至少一种氯代醇和/或其酯的方法，该方法包括至少一个反应步骤，其中多羟基化脂族烃和/或 其酯在反应条件下与氯化氢接触以产生氯醇和/或其酯，随后是至少一个下游处理步骤，其中反应步骤的流出物被处理，其中下游处理步骤在以下条件下进行： 含有氯代醇和/或其酯的流出物保持在小于120℃的温度。本发明允许氯化氢从氢氯化反应的产物中释放最小化，从而减少下游设备的腐蚀并减少 需要使用昂贵的耐腐蚀材料。

公开(公告)号：US20100152499A1

公开(公告)日：2010-06-17

申请号：US12595396

申请日：2008-04-11

申请人： John R. Briggs ,  Bruce D. Hook ,  William J. Kruper, JR. ,  Anil Mehta ,  Robert M. Alvarado ,  Sascha Noormann ,  Perry S. Basile

发明人： John R. Briggs ,  Bruce D. Hook ,  William J. Kruper, JR. ,  Anil Mehta ,  Robert M. Alvarado ,  Sascha Noormann ,  Perry S. Basile

IPC分类号： C07C31/36 ,  B01J19/00

CPC分类号： C07C29/62 ,  C07C31/36 ,  C07C31/42

摘要： The present invention relates to a process for converting at least one multihydroxylated-aliphatic hydrocarbon and/or an ester thereof to at least one chlorohydrin and/or an ester thereof, comprising at least one reaction step in which the multihydroxylated-aliphatic hydrocarbon and/or ester thereof is contacted with hydrogen chloride under reaction conditions to produce the chlorohydrin and/or ester thereof, followed by at least one downstream processing step in which the effluents of the reaction step are processed, wherein the downstream processing step is performed in such conditions that the effluents containing the chlorohydrin and/or ester thereof are kept at a temperature of less than 12O° C. The invention allows to minimize the liberation of hydrogen chloride from the products of the hydrochlorination reaction, hence reducing the corrosion of the downstream equipment and reducing M the need to use costly corrosion resistant materials.

摘要翻译： 本发明涉及将至少一种多羟基化脂族烃和/或其酯转化为至少一种氯代醇和/或其酯的方法，该方法包括至少一个反应步骤，其中多羟基化脂族烃和/或 其酯在反应条件下与氯化氢接触以产生氯醇和/或其酯，随后是至少一个下游处理步骤，其中反应步骤的流出物被处理，其中下游处理步骤在以下条件下进行： 含有氯代醇和/或其酯的流出物保持在低于120℃的温度。本发明允许氯化氢从氢氯化反应的产物中释放最小化，从而减少下游设备的腐蚀并减少 M需要使用昂贵的耐腐蚀材料。

公开(公告)号：US08558030B2

公开(公告)日：2013-10-15

申请号：US13002719

申请日：2009-07-22

申请人： John R. Briggs ,  Jasson T. Patton ,  Sonet Vermaire-Louw ,  Peter M. Margl ,  Henk Hagen ,  Daryoosh Beigzadeh

发明人： John R. Briggs ,  Jasson T. Patton ,  Sonet Vermaire-Louw ,  Peter M. Margl ,  Henk Hagen ,  Daryoosh Beigzadeh

IPC分类号： C07C41/06 ,  C07C43/178 ,  C07C1/20

CPC分类号： C07C41/06 ,  C07C1/20 ,  C07C43/178 ,  C07C43/15

摘要： In an improved process for telomerizing butadiene, contact butadiene and an organic hydroxy compound represented by formula ROH (I), wherein R is a substituted or unsubstituted C1-C20-hydrocarbyl and the organic hydroxy compound is not glycerol, in a reaction fluid in the presence of a palladium catalyst and a phosphine ligand represented by formula PAr3 (II), wherein each Ar is independently a substituted or unsubstituted aryl having a hydrogen atom on at least one ortho position, at least two Ar groups are ortho-hydrocarbyloxyl substituted aryls. The phosphine ligand has a total of two (2), three (3), four (4), five (5), or six (6) substituted or unsubstituted C1-C20-hydrocarbyloxyls, and optionally, any two adjacent substituents on an Ar group can be bonded to form a 5- to 7-membered ring.

摘要翻译： 在用于调聚丁二烯的改进方法中，接触丁二烯和由式ROH（I）表示的有机羟基化合物，其中R是取代或未取代的C 1 -C 20 - 烃基，有机羟基化合物不是甘油，在 存在钯催化剂和由式PAr 3（II）表示的膦配体，其中每个Ar独立地是在至少一个邻位具有氢原子的取代或未取代的芳基，至少两个Ar基团是邻 - 烃氧基取代的芳基。 膦配体共有二（2），三（3），四（4），五（5）或六（6）取代或未取代的C1-C20烃氧基，任选地，任何两个相邻的取代基 Ar基团可以键合形成5-至7-元环。

公开(公告)号：US5225387A

公开(公告)日：1993-07-06

申请号：US691400

申请日：1991-04-25

申请人： John R. Briggs ,  John M. Maher ,  Arnold M. Harrison

发明人： John R. Briggs ,  John M. Maher ,  Arnold M. Harrison

IPC分类号： C07C29/36 ,  C07C45/58

CPC分类号： C07C29/36 ,  C07C45/58

摘要： A process for producing a 1,3-diol, e.g., 1,3-propanediol, or a 3-hydroxyaldehyde is disclosed which comprises contacting a combination of an epoxide, carbon monoxide and hydrogen in the present of a rhodium-containing catalyst effective to promote the hydroformylation of the epoxide at conditions effective to form at least one of a 1,3-diol and a 3-hydroxyaldehyde, the contacting occurring in the substantial absence of a promoting amount of alkali metal ions, and at least a portion of the rhodium-containing catalyst being formed substantially without incorporation of the epoxide. A process for producing such rhodium-containing compositions is also disclosed.

摘要翻译： 公开了一种生产1,3-二醇，例如1,3-丙二醇或3-羟基醛的方法，其包括将含有铑的催化剂中的环氧化物，一氧化碳和氢气的组合接触， 在有效形成1,3-二醇和3-羟基醛中的至少一种的条件下促进环氧化物的加氢甲酰基化，所述接触在基本上不存在促进量的碱金属离子的情况下发生，并且至少部分 铑催化剂基本上不加入环氧化物形成。 还公开了制备这种含铑组合物的方法。

公开(公告)号：US5210318A

公开(公告)日：1993-05-11

申请号：US670876

申请日：1991-03-18

申请人： John R. Briggs ,  John M. Maher ,  Arnold M. Harrison

发明人： John R. Briggs ,  John M. Maher ,  Arnold M. Harrison

IPC分类号： B01J31/16 ,  B01J31/18 ,  B01J31/20 ,  C07B61/00 ,  C07C27/22 ,  C07C29/10 ,  C07C29/141 ,  C07C29/36 ,  C07C29/38 ,  C07C31/20 ,  C07C45/50 ,  C07C45/58 ,  C07C47/19

CPC分类号： C07C29/36 ,  B01J31/185 ,  B01J31/20 ,  C07C45/58 ,  B01J2531/822

摘要： A process for producing a 1,3-diol, e.g., 1,3-propanediol, and/or a 3-hydroxyaldehyde, e.g., 3-hydroxypropionaldehyde, is disclosed which comprises contacting a combination of an epoxide, carbon monoxide and hydrogen in the presence of a rhodium-containing catalyst composition effective to promote the hydroformylation of the epoxide at conditions effective to form at least one of a 1,3-diol and a 3-hydroxyaldehyde. The rhodium-containing catalyst composition comprises an anionic rhodium-containing complex. A promoter component is preferably provided to enhance at least one of the rate and selectivity of the epoxide hydroformylation reaction Rhodium-containing compositions and a processes for producing rhodium-containing compositions are also disclosed.

公开(公告)号：US09174905B2

公开(公告)日：2015-11-03

申请号：US13883688

申请日：2011-12-14

申请人： John R. Briggs ,  Jasson T. Patton ,  Daryoosh Beigzadeh ,  Peter M. Margl ,  Henk Hagen ,  Sonet Vermaire-Louw

发明人： John R. Briggs ,  Jasson T. Patton ,  Daryoosh Beigzadeh ,  Peter M. Margl ,  Henk Hagen ,  Sonet Vermaire-Louw

IPC分类号： C07F9/50 ,  C07C41/06 ,  C07C1/20 ,  C07C41/20

CPC分类号： C07C41/06 ,  C07C1/20 ,  C07C41/20 ,  C07F9/5022 ,  C07C43/15 ,  C07C43/04 ,  C07C11/02

摘要： A process for the telomerization of butadiene comprises reacting 1,3-butadiene and an alkanol, in the presence of a catalyst promoter and an alkoxydimerization catalyst comprising a Group VIII transition metal and a triarylphosphine ligand, which includes one phenyl that is mono-ortho-alkoxy substituted and at least one other phenyl including at least one substituent that withdraws electrons from the phosphorus atom. The product includes an alkoxy-substituted octadiene, which may then be used to produce 1-octene. The catalyst shows improved stability, activity and selectivity toward the alkoxy-substituted octadiene.

摘要翻译： 用于丁二烯调聚的方法包括在催化剂促进剂和包含第VIII族过渡金属和三芳基膦配体的烷氧基二聚催化剂的存在下，使1,3-丁二烯和链烷醇反应，其包括一个苯基， 烷氧基取代的和至少一种其它苯基，包括至少一个从磷原子撤出电子的取代基。 该产物包括烷氧基取代的辛二烯，然后可以用它来生产1-辛烯。 该催化剂显示改进的对烷氧基取代的辛二烯的稳定性，活性和选择性。

公开(公告)号：US09067845B2

公开(公告)日：2015-06-30

申请号：US13697038

申请日：2011-05-19

申请人： Tina L. Arrowood ,  William J. Kruper, Jr. ,  John R. Briggs

发明人： Tina L. Arrowood ,  William J. Kruper, Jr. ,  John R. Briggs

IPC分类号： C07C51/363 ,  C07C69/76 ,  C07C69/02 ,  C07B41/12 ,  C07C29/62 ,  C07C29/86 ,  C07C67/11 ,  C07C67/58 ,  C07C67/08 ,  C07C67/10

CPC分类号： C07B41/12 ,  C07C29/62 ,  C07C29/86 ,  C07C67/08 ,  C07C67/10 ,  C07C67/11 ,  C07C67/58 ,  C07C31/36 ,  C07C69/63 ,  C07C69/78

摘要： A process for producing a chlorohydrin, an ester of a chlorohydrin, or a mixture thereof including the steps of contacting, in a hydrochlorination reactor, a multihydroxylated aliphatic hydrocarbon, an ester of a multihydroxylated aliphatic hydrocarbon, or a mixture thereof with a source of a hydrogen chloride, in the presence of a hydrophobic or extractable carboxylic acid catalyst is provided.

摘要翻译： 一种生产氯代醇，氯代醇酯或其混合物的方法，包括以下步骤：在氢氯化反应器中将多羟基化脂族烃，多羟基化脂族烃或其混合物的酯与 提供了在疏水性或可提取的羧酸催化剂存在下的氯化氢。