OBTAINING OPTICAL TISSUE PROPERTIES
    1.
    发明申请
    OBTAINING OPTICAL TISSUE PROPERTIES 审中-公开
    获得光学组织特性

    公开(公告)号:US20090326385A1

    公开(公告)日:2009-12-31

    申请号:US12517249

    申请日:2007-11-29

    IPC分类号: A61B6/00

    摘要: This application describes a medical device (230) for obtaining optical tissue properties of a target material. The medical device (230) comprises an elongated body (231) having a longitudinal axis (232) and an optical fiber being integrated within the elongated body (231). The optical fiber has a second fiber end (242, 242a, 242b), which is arranged at a side wall (233) of the elongated body (231) and which provides a lateral field of view with respect to the longitudinal axis (232). According to an embodiment many optical fibers are integrated each having an optical outlet (242, 242a, 242b) around the elongated body (231). Using the outlets (242, 242a, 242b) to do diffuse optical tomography and also use optical fibers to do an optical inspection, one can get information on the presence of tumors in a volume around the medical device (230) and a tissue characterization in the vicinity of the medical device (230). Thereby, an optical biopsy may be carried out, wherein no real tissue is removed. According to another embodiment an optical detection system is integrated into a real biopsy needle (330) allowing inspection and taking real biopsy simultaneously.

    摘要翻译: 本申请描述了用于获得目标材料的光学组织性质的医疗装置(230)。 医疗装置(230)包括具有纵向轴线(232)的细长主体(231)和整合在细长主体(231)内的光纤。 光纤具有第二光纤端(242,242a,242b),其被布置在细长主体(231)的侧壁(233)处,并且相对于纵向轴线(232)提供横向视场, 。 根据实施例,许多光纤被集成为每个都具有围绕细长主体(231)的光学出口(242,242a,242b)。 使用出口(242,242a,242b)进行漫射光学层析成像,并且还使用光纤进行光学检查,可以获得关于医疗装置周围的体积肿瘤的存在的信息(230)和组织表征 医疗装置(230)的附近。 因此,可以进行光学活检,其中不去除真实的组织。 根据另一个实施例,光学检测系统被集成到实际的活检针(330)中,允许同时进行检查和进行实际的活检。

    ANALYZING BIOLOGICAL CELL MATERIAL BASED ON DIFFERENT INTERACTIONS BETWEEN ILLUMINATION LIGHT AND CELL COMPONENTS
    2.
    发明申请
    ANALYZING BIOLOGICAL CELL MATERIAL BASED ON DIFFERENT INTERACTIONS BETWEEN ILLUMINATION LIGHT AND CELL COMPONENTS 审中-公开
    基于照明光和细胞成分之间的不同相互作用分析生物细胞材料

    公开(公告)号:US20100105022A1

    公开(公告)日:2010-04-29

    申请号:US12530787

    申请日:2008-03-10

    IPC分类号: C12Q1/00 C12M1/34

    摘要: It is described a device (100) for analyzing biological cell material (115). The device (100) comprises a light source arrangement (120), which is adapted for directing a first (131) and a second illumination light (132) towards the cell material (115), wherein the first (131) and the second (132) illumination light comprises a first and a second spectral radiation component, respectively. The device (100) further comprises a detector arrangement (170), which is adapted for receiving a first measurement light (151) based on a first interaction of the first illumination light (131) with the cell material (115) and a second measurement light (152) based on a second interaction of the second illumination light (152) with the cell material (115). Further, the device (100) comprises an evaluation unit (180), which is coupled the detector arrangement (170) and which is adapted to evaluate a first signal (171a) and a second signal (171b) being indicative for the first (151) and the second measurement light (151), respectively. The device (100) may be used for accomplishing ultraviolet DNA image cytometryin combination with autofluorescence measurements of NAD(P)H.

    摘要翻译: 描述了用于分析生物细胞材料(115)的装置(100)。 所述装置(100)包括光源装置(120),其适于将第一(131)和第二照明光(132)引向所述电池材料(115),其中所述第一(131)和所述第二(131) 132)照明光分别包括第一和第二光谱辐射分量。 装置(100)还包括检测器装置(170),其适于基于第一照明光(131)与电池材料(115)的第一相互作用接收第一测量光(151)和第二测量 基于第二照明光(152)与电池材料(115)的第二相互作用的光(152)。 此外,设备(100)包括评估单元(180),其耦合检测器装置(170)并且适于评估第一信号(171a)和第二信号(171b),其指示第一(151) )和第二测量光(151)。 装置(100)可用于实现与NAD(P)H的自发荧光测量结合的紫外线DNA图像细胞计数法。

    Method and system for imaging samples
    4.
    发明授权
    Method and system for imaging samples 有权
    成像样本的方法和系统

    公开(公告)号:US08450703B2

    公开(公告)日:2013-05-28

    申请号:US12678781

    申请日:2008-07-23

    IPC分类号: G01N21/64

    摘要: The invention provides a method for imaging samples, at least comprising: —staining of a sample with a first marker material and with a second marker material; —utilizing the first marker material in a focusing step for focusing an imaging device with respect to the sample; and —utilizing the second marker material and the imaging device, which has been focused in the focusing step, in an imaging step to acquire an image of the sample. The invention also relates to a system for imaging samples.

    摘要翻译: 本发明提供了一种用于成像样品的方法,至少包括:用第一标记材料和第二标记材料染色样品; - 在聚焦步骤中利用所述第一标记材料,用于相对于所述样品聚焦成像装置; 并且在成像步骤中利用聚焦在聚焦步骤中的第二标记材料和成像装置来获取样本的图像。 本发明还涉及用于成像样本的系统。

    METHOD AND SYSTEM FOR IMAGING SAMPLES
    5.
    发明申请
    METHOD AND SYSTEM FOR IMAGING SAMPLES 有权
    用于成像样本的方法和系统

    公开(公告)号:US20100214430A1

    公开(公告)日:2010-08-26

    申请号:US12678781

    申请日:2008-07-23

    IPC分类号: H04N5/228 G06K9/62

    摘要: The invention provides a method for imaging samples, at least comprising:—staining of a sample with a first marker material and with a second marker material;—utilizing the first marker material in a focusing step for focusing an imaging device with respect to the sample; and—utilizing the second marker material and the imaging device, which has been focused in the focusing step, in an imaging step to acquire an image of the sample. The invention also relates to a system for imaging samples.

    摘要翻译: 本发明提供了一种用于成像样品的方法,至少包括: - 用第一标记材料和第二标记材料染色样品; - 在聚焦步骤中利用第一标记材料,用于相对于样品聚焦成像装置 ; 并且利用已经聚焦在聚焦步骤中的第二标记材料和成像装置在获取样本的图像的成像步骤中。 本发明还涉及用于成像样本的系统。

    FIBER-OPTIC SCANNER
    8.
    发明申请
    FIBER-OPTIC SCANNER 有权
    光纤扫描仪

    公开(公告)号:US20100207015A1

    公开(公告)日:2010-08-19

    申请号:US12668905

    申请日:2008-07-14

    IPC分类号: G02B26/10

    摘要: A fiber scanning system is provided comprising a housing (102) with a fiber (13), the fiber (13) comprising a fixed part and a free end, the fixed part being attached to a bottom of the housing (102) and the fiber (13) extending parallel to the wall of the housing (102). At least one electrical coil (12) is attached to the wall at a position in between the fixed part and the free end of the fiber (13), a winding of the electrical coil (12) being in a plane parallel to the fiber (13). A magnet (11) is attached to the fiber (13), such that the electrical coil (12) may induce a force on the magnet (11). The magnet (11) is attached to the fiber (13) at a position just before or after the electrical coil (12), a width of the magnet (11) being such that the magnet (11) extends over the electrical coil (12).

    摘要翻译: 提供一种纤维扫描系统,其包括具有纤维(13)的壳体(102),所述纤维(13)包括固定部分和自由端,所述固定部分附接到所述壳体(102)的底部,并且所述纤维 (13)平行于壳体(102)的壁延伸。 至少一个电线圈(12)在所述固定部分和所述光纤(13)的所述自由端之间的位置处附接到所述壁,所述电线圈(12)的绕组处于与所述光纤平行的平面( 13)。 磁体(11)附着在光纤(13)上,使得电线圈(12)可以在磁铁(11)上产生一个力。 磁体(11)在刚好在电线圈(12)之前或之后的位置处附接到光纤(13),磁体(11)的宽度使得磁体(11)在电线圈(12)上方延伸 )。