公开(公告)号：US09291579B2

公开(公告)日：2016-03-22

申请号：US14111772

申请日：2012-04-16

Applicant: Bin Hu ,  Christopher John Lawrence

Inventor： Bin Hu ,  Christopher John Lawrence

IPC: G01N23/04 ,  G01N23/12

CPC classification number: G01N23/046 ,  G01N23/12 ,  G01N2223/419 ,  G01N2223/601 ,  G01N2223/635

Abstract: A method of estimating chordal holdup values of gas, oil, and water (εG, εO, εW) for tomographic imaging of a three-phase flow through a volume, including: providing an X-ray source for irradiating through said volume and X-ray sensors for discriminating between a first and a second radiation bands, conducting first calibration measurements (IGS, IOS, IWS) of said first radiation band, conducting second calibration measurements (IGH, IOH, IWH) of said second radiation band, arranging a mixture of two or more fluids, irradiating said volume and conducting X-ray measurements (IS, IH) in said radiation bands, establishing a relationship between a function of holdup values f(εG, εW) of at least gas and water and said X-ray measurements (IS, IH), searching holdup values (εG, εW) that minimize said function of holdup values f(εG, εW) under the constraints of the sum of said holdup values is more than or equal to zero and less than or equal to one, i.e. that 0≦εG+εW≦1.

Abstract translation: 一种估计气体，油和水（＆Egr; G，＆egr; O，＆egr; W）的弦状滞留值用于通过体积的三相流的断层成像的方法，包括：提供用于照射的X射线源 通过所述体积和X射线传感器来区分第一和第二辐射带，进行所述第一辐射带的第一校准测量（IGS，IOS，IWS），进行所述第二辐射带的第二校准测量（IGH，IOH，IWH） 辐射带，布置两种或更多种流体的混合物，照射所述体积并在所述辐射带中进行X射线测量（IS，IH），建立保持值f（＆egr; G，＆egr; W）的函数之间的关系， 至少气体和水以及所述X射线测量（IS，IH），搜索在约束条件下使滞留值f（＆egr; G，＆egr; W）的所述功能最小化的保持值（＆egr; G，＆egr; W） 所述保持值的总和大于或等于零且小于或等于1，即tha t 0＆nlE;＆egr; G +＆egr; W＆nlE; 1。

公开(公告)号：US20230139282A1

公开(公告)日：2023-05-04

申请号：US17795349

申请日：2021-02-02

Applicant: Manuel DE LERA RUIZ ,  Paola FAVUZZA ,  Zhuyan GUO ,  Bin HU ,  Michael J. KELLY, III ,  Zhiyu LEI ,  John A. MCCAULEY ,  David B. OLSEN ,  Brad SLEEBS ,  Tony TRIGLIA ,  Dongmei ZHAN ,  Lianyun ZHAO ,  Merck Sharp & Dohme LLC ,  The Walter and Eliza Hall Institute of Medical Research ,  MSD R&D (China) Co., Ltd.

Inventor： Manuel de Lera Ruiz ,  Paola Favuzza ,  Zhuyan Guo ,  Bin Hu ,  Michael J. Kelly, III ,  Zhiyu Lei ,  John A. McCauley ,  David B. Olsen ,  Brad Sleebs ,  Tony Triglia ,  Dongmei Zhan ,  Lianyun Zhao

IPC: A61K31/513 ,  A61K45/06 ,  C07D405/12 ,  C07D233/88 ,  C07D405/14 ,  C07D417/14 ,  C07D491/18 ,  A61P33/06 ,  A61K31/529 ,  A61K31/5377 ,  C07D401/06

Abstract: Provided are methods of treating malaria comprising administration of compounds of Formula (I) or a pharmaceutically acceptable salt thereof, to a subject in need thereof, wherein the variables are as defined herein. Also provided are uses of the compounds of Formula (I), as defined herein, for treating a Plasmodium infection, and for treating malaria. Also provided are methods of treatment further comprising administration of one or more additional anti-malarial compounds.

公开(公告)号：US20140302427A1

公开(公告)日：2014-10-09

申请号：US13977638

申请日：2011-12-29

Applicant: Bin Hu ,  Vivek K. Singh ,  Sungwon Kim ,  Chulwoo Oh ,  Mehmet E. Yavuz

Inventor： Bin Hu ,  Vivek K. Singh ,  Sungwon Kim ,  Chulwoo Oh ,  Mehmet E. Yavuz

IPC: G03F1/68

CPC classification number: G03F1/68 ,  G03F1/26 ,  G03F1/70

Abstract: Improved mask layout patterns are described for closely spaced primitives in phase shift photolithography masks. In one example, at least a portion of a photolithography mask layout is decomposed into primitives. Jogs are identified from among the primitives, the jogs being characterized by three adjacent corners. E-fields are determined for the identified jogs and are applied to synthesize an electric field at a substrate. The mask layout is corrected using the synthesized electric field and a printed wafer pattern is calculated.

Abstract translation: 在相移光刻掩模中描述了用于紧密间隔的基元的改进的掩模布局图案。 在一个示例中，光刻掩模布局的至少一部分被分解为基元。 从原始图像中识别出慢跑，其特征在于三个相邻角落。 为识别的点动确定电场，并且被应用于在衬底处合成电场。 使用合成电场校正掩模布局，并计算印刷晶片图案。

公开(公告)号：US20140199264A1

公开(公告)日：2014-07-17

申请号：US14005430

申请日：2012-03-16

Applicant: Craig A. Coburn ,  Stuart B. Rosenblum ,  Joseph A. Kozlowski ,  Richard Soll ,  Hao Wu ,  Bin Hu ,  Bin Zhong ,  Dahai Wang ,  Changmao Shen ,  Fei Sun

Inventor： Craig A. Coburn ,  Stuart B. Rosenblum ,  Joseph A. Kozlowski ,  Richard Soll ,  Hao Wu ,  Bin Hu ,  Bin Zhong ,  Dahai Wang ,  Changmao Shen ,  Fei Sun

IPC: A61K31/5383 ,  A61K45/06 ,  A61K31/4178 ,  C07D498/06 ,  C07D493/06

CPC classification number: A61K31/5383 ,  A61K31/4178 ,  A61K45/06 ,  C07D491/06 ,  C07D493/06 ,  C07D498/06

Abstract: The present invention relates to novel Tetracyclic Xanthene Derivatives of Formula (I) and pharmaceutically acceptable salts thereof, wherein A, Y1, Y2, Z, Ra, Rb, R1a, R1b and R2 are as defined herein. The present invention also relates to compositions comprising at least one Tetracyclic Xanthene Derivative, and methods of using the Tetracyclic Xanthene Derivatives for treating or preventing HCV infection in a patient.

Abstract translation: 本发明涉及式（I）的新型四环Xanthene衍生物及其药学上可接受的盐，其中A，Y1，Y2，Z，Ra，Rb，R1a，R1b和R2如本文所定义。 本发明还涉及包含至少一种四环Xanthene衍生物的组合物，以及使用四环Xanthene衍生物治疗或预防患者HCV感染的方法。

公开(公告)号：US20130290418A1

公开(公告)日：2013-10-31

申请号：US13459002

申请日：2012-04-27

Applicant: Yanghua Liu ,  Bin Hu ,  Erzhen Liang

Inventor： Yanghua Liu ,  Bin Hu ,  Erzhen Liang

IPC: G06F15/16

CPC classification number: H04N21/6405 ,  H04L12/1854

Abstract: A method, a system and computer readable storage media facilitate receiving a data stream from a host media server that is outside of a network, designating a multicasting source within the network to receive the data stream from the host media server, and multicasting the data stream from the multicasting source to a plurality of client devices within the network.

Abstract translation: 方法，系统和计算机可读存储介质便于从网络外部的主机媒体服务器接收数据流，指定网络内的多播源以从主机媒体服务器接收数据流，并且多播数据流 从组播源到网络内的多个客户端设备。

公开(公告)号：US08509969B2

公开(公告)日：2013-08-13

申请号：US12810704

申请日：2008-12-26

Applicant: Zhiqiang Chen ,  Shangmin Sun ,  Xining Xu ,  Weizhi Lin ,  Yanwei Xu ,  Zhenbin Guo ,  Bin Hu ,  Guang Yang

Inventor： Zhiqiang Chen ,  Shangmin Sun ,  Xining Xu ,  Weizhi Lin ,  Yanwei Xu ,  Zhenbin Guo ,  Bin Hu ,  Guang Yang

IPC: G05D1/00

CPC classification number: B61L25/041 ,  B61L1/14 ,  B61L1/161 ,  B61L1/165 ,  B61L25/028 ,  B61L25/045

Abstract: The present invention relates to a method and system for automatically identifying various information of a train. The method comprises using sensors to collect wheelbase information, processing the information by signal data processing devices, thereby providing information of a train, namely: arranging a plurality of sensors along the rail in the incoming direction of the train, dividing the sensors into at least three groups, each group comprising at least two sensors; analyzing and processing the signal data stream obtained from the sensors and collected when a train vehicle passes by, thereby acquiring the speed and wheelbase of the train, and further acquiring the train segmentation information; determining the vehicle type; acquiring hook locating information; determining the train arrival; determining the train departure; acquiring vehicle number. The present invention further comprises a system for carrying out the information method for automatically identifying information of a train. The present invention can provide a plurality of types of train information with high accuracy, and is easy to be carried out.

Abstract translation: 本发明涉及一种用于自动识别列车的各种信息的方法和系统。 该方法包括使用传感器来收集轴距信息，通过信号数据处理装置处理信息，从而提供列车的信息，即沿列车的输入方向沿轨道布置多个传感器，至少将传感器分成 三组，每组包括至少两个传感器; 分析和处理从传感器获得的信号数据流，并在火车车辆通过时收集，从而获取列车的速度和轴距，并进一步获取列车分段信息; 确定车辆类型; 获取挂钩定位信息; 确定火车到达; 确定列车离开; 获取车辆编号。 本发明还包括一种用于执行用于自动识别列车信息的信息方法的系统。 本发明能够提供高精度的多种列车信息，容易进行。

公开(公告)号：US08404403B2

公开(公告)日：2013-03-26

申请号：US12824037

申请日：2010-06-25

Applicant: Shem Ogadhoh ,  Raguraman Venkatesan ,  Kevin J. Hooker ,  Sungwon Kim ,  Bin Hu ,  Vivek Singh ,  Bikram Baidya ,  Prasad Narendra Atkar ,  Seongtae Jeong

Inventor： Shem Ogadhoh ,  Raguraman Venkatesan ,  Kevin J. Hooker ,  Sungwon Kim ,  Bin Hu ,  Vivek Singh ,  Bikram Baidya ,  Prasad Narendra Atkar ,  Seongtae Jeong

IPC: G03F1/68

CPC classification number: G03F1/36 ,  G03F1/68 ,  G06F17/50

Abstract: Described herein is mask design and modeling for a set of masks to be successively imaged to print a composite pattern on a substrate, such as a semiconductor wafer. Further described herein is a method of double patterning a substrate with the set of masks. Also described herein is a method of correcting a drawn pattern of one of the mask levels based on a predicted pattern contour of the other of the mask levels. Also described herein is a method of modeling a resist profile contour for a mask level in which photoresist is applied onto a inhomogeneous substrate, as well as method of predicting a resist profile of a Boolean operation of two masks.

Abstract translation: 这里描述的是要连续成像以在诸如半导体晶片的衬底上打印复合图案的一组掩模的掩模设计和建模。 本文进一步描述的是使用该组掩模对衬底进行双重图案化的方法。 这里还描述了一种基于掩模级别中的另一个的预测图案轮廓来校正掩模级中的一个的绘制图案的方法。 本文还描述了一种对光致抗蚀剂施加到非均匀衬底上的掩模级的抗蚀剂轮廓轮廓建模方法，以及预测两个掩模的布尔运算的抗蚀剂轮廓的方法。

公开(公告)号：US20120316200A1

公开(公告)日：2012-12-13

申请号：US13578653

申请日：2011-04-07

Applicant: Linus S. Lin ,  Richard Soll ,  Jingchao Dong ,  Hao Wu ,  Takao Suzuki ,  Bin Hu ,  Dejun Liu ,  Jinglai Hao ,  Ming Xu

Inventor： Linus S. Lin ,  Richard Soll ,  Jingchao Dong ,  Hao Wu ,  Takao Suzuki ,  Bin Hu ,  Dejun Liu ,  Jinglai Hao ,  Ming Xu

IPC: C07D213/69 ,  C07D401/10 ,  A61K31/4709 ,  C07D401/12 ,  A61P25/22 ,  A61P3/04 ,  A61P3/10 ,  A61P1/16 ,  A61P25/24 ,  A61K31/4418 ,  A61K31/444

CPC classification number: C07D401/12 ,  C07D213/69

Abstract: The present invention is directed to novel phenylpyridone derivative compounds. The compounds act as a melanin concentrating hormone receptor antagonists, and can be useful in preventing, treating or acting as a remedial agent for various circular system diseases, nervous system diseases, metabolic diseases, genital diseases, respiratory diseases and digestive diseases.

Abstract translation: 本发明涉及新的苯基吡啶酮衍生物化合物。 该化合物作为黑色素浓缩激素受体拮抗剂起作用，可用于预防，治疗或作为各种循环系统疾病，神经系统疾病，代谢疾病，生殖器疾病，呼吸系统疾病和消化系统疾病的补救剂。

公开(公告)号：US20120145950A1

公开(公告)日：2012-06-14

申请号：US13405027

申请日：2012-02-24

Applicant: Deepak Mahulikar ,  Yuhu Wang ,  Ken A. Delbridge ,  Gert R.M. Moyaerts ,  Saeed H. Mohseni ,  Nichole R. Koontz ,  Bin Hu ,  Liqing Wen

Inventor： Deepak Mahulikar ,  Yuhu Wang ,  Ken A. Delbridge ,  Gert R.M. Moyaerts ,  Saeed H. Mohseni ,  Nichole R. Koontz ,  Bin Hu ,  Liqing Wen

IPC: C09K13/00 ,  B82Y30/00

CPC classification number: C23F3/04 ,  C01B33/1435 ,  C01B33/1485 ,  C01P2004/62 ,  C01P2004/64 ,  C01P2006/80 ,  C09G1/02 ,  C09K3/1463 ,  C09K3/1472 ,  H01L21/31053 ,  H01L21/3212

Abstract: An ultrapure colloidal silica dispersion comprising colloidal silica particles having a mean or aggregate particle size from about 10 to about 200 nm, wherein the colloidal silica dispersion has less than 200 ppb, of each trace metal impurity disposed therein, excluding potassium and sodium, and have less than 2 ppm residual alcohol. A method for producing and using the same is also disclosed.

Abstract translation: 一种超纯胶态二氧化硅分散体，其包含平均或聚集体粒径为约10至约200nm的胶体二氧化硅颗粒，其中胶态二氧化硅分散体中除了钾和钠之外的每种痕量金属杂质少于200ppb，并且具有 小于2ppm的残余酒精。 还公开了其制造和使用方法。

公开(公告)号：US20090115744A1

公开(公告)日：2009-05-07

申请号：US11935697

申请日：2007-11-06

Applicant: CHARLES C. ZHANG ,  Peijian Yuan ,  Belinda Liu ,  Bin Hu ,  Shinhwa Li ,  Jen-Lung David Tai

Inventor： CHARLES C. ZHANG ,  Peijian Yuan ,  Belinda Liu ,  Bin Hu ,  Shinhwa Li ,  Jen-Lung David Tai

IPC: G06F3/033

CPC classification number: G06F3/03545 ,  G06F3/0346

Abstract: A writing system includes a pen with a two-dimensional optical sensor and a three dimensional acceleration sensor positioned to indicate movement of the pen. A calibrator is coupled to receive path coordinate signals from the two-dimensional optical sensor and the three dimensional acceleration sensor. The calibrator and the two-dimensional optical sensor and the three dimensional acceleration sensor are configured to operate in one of two modes, a contactable mode of operation wherein both the two-dimensional optical sensor and the three dimensional acceleration sensor supply path coordinate signals to the coordinator and a contactless mode of operation wherein only the three dimensional acceleration sensor supplies path coordinate signals to the coordinator.

Abstract translation: 书写系统包括具有二维光学传感器的笔和定位成指示笔的移动的三维加速度传感器。 校准器被耦合以从二维光学传感器和三维加速度传感器接收路径坐标信号。 校准器和二维光学传感器和三维加速度传感器被配置为以两种模式之一操作，即可操作的操作模式，其中二维光学传感器和三维加速度传感器将路径坐标信号提供给 协调器和非接触式操作模式，其中只有三维加速度传感器向协调器提供路径坐标信号。