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公开(公告)号：US20150299757A1
公开(公告)日：2015-10-22
申请号：US14753741
申请日：2015-06-29
Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
Inventor： Aditya RAJAGOPAL , Axel SCHERER , Michael D. HENRY , Sameer WALAVALKAR , Thomas A. TOMBRELLO , Andrew P. HOMYK
IPC: C12Q1/02
CPC classification number: C12Q1/02 , A61B5/04001 , G01N27/3275 , G01N27/4146 , G01R1/06711 , G01R1/07342 , H01L29/413 , H01L29/42376 , H01L29/4966 , H01L29/66477 , H01L29/78 , H01L29/7831
Abstract: The basic structure and functionality of a probe as disclosed herein allows for flexibly incorporating into the probe, various sensing elements for various sensing applications. Two example applications among these various sensing applications include bio-sensing and chemical-sensing applications. For bio-sensing applications the probe, which is fabricated upon a silicon substrate, includes a bio-sensing element such as a nano-pillar transistor, and for chemical-sensing applications the probe includes a sensing element that has a functionalized contact area whereby the sensing element generates a voltage when exposed to one or more chemicals of interest.
Abstract translation: 本文公开的探针的基本结构和功能允许灵活地并入到探针中，用于各种感测应用的各种感测元件。 这些各种感测应用中的两个示例应用包括生物感测和化学感测应用。 对于生物感测应用，制造在硅衬底上的探针包括诸如纳米柱晶体管的生物感测元件，并且对于化学感测应用，探针包括具有功能化接触区域的感测元件， 当暴露于感兴趣的一种或多种化学品时，感测元件产生电压。
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2.发明申请PLASMONICS NANOSTRUCTURES FOR MULTIPLEXING IMPLANTABLE SENSORS 有权用于多路复用传感器的PLASMONICS NANOSTRUCTURES公开(公告)号：US20150223738A1
公开(公告)日：2015-08-13
申请号：US14621265
申请日：2015-02-12
Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
Inventor： Sameer WALAVALKAR , Chieh-feng CHANG , Axel SCHERER
IPC: A61B5/1459 , A61B5/07 , A61B5/00
CPC classification number: A61B5/1459 , A61B5/0075 , A61B5/076 , A61B5/14735 , A61B5/6848 , A61B5/686 , A61B2562/0285 , A61B2562/066 , A61B2562/12 , A61B2562/223 , B01J2219/00509 , B01J2219/0052 , B01J2219/00531 , B82Y30/00 , B82Y40/00 , G01N21/658
Abstract: Methods and systems for nanopillar sensors are described. Nanopillars can be defined on a substrate, and metal deposited on the nanopillars. A thermal treatment can reflow the metal on the nanopillars forming metallic bulbs on the top end of the nanopillars. These structures can have enhanced optical detection when functionalized with biological agents, or can detect gases, particles and liquids through interaction with the metal layer on the nanopillars.
Abstract translation: 描述了纳米柱传感器的方法和系统。 纳米玻璃可以在基底上定义，金属沉积在纳米柱上。 热处理可以回流纳米柱上的金属，在纳米柱的顶端形成金属灯泡。 这些结构可以在用生物制剂进行功能化时具有增强的光学检测，或者可以通过与纳米柱上的金属层的相互作用来检测气体，颗粒和液体。
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3.发明申请公开(公告)号：US20140319459A1
公开(公告)日：2014-10-30
申请号：US14329748
申请日：2014-07-11
Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
Inventor： Andrew P. HOMYK , Michael D. HENRY , Axel SCHERER , Sameer WALAVALKAR
IPC: H01L29/06 , H01L31/0352 , H01L33/06
CPC classification number: H01L31/035227 , B82Y10/00 , B82Y40/00 , H01L21/02381 , H01L21/0243 , H01L21/02521 , H01L21/0259 , H01L21/02639 , H01L29/0665 , H01L29/0676 , H01L29/127 , H01L29/267 , H01L29/413 , H01L29/66439 , H01L29/775 , H01L33/06 , Y10S977/762
Abstract: Methods for fabricating self-aligned heterostructures and semiconductor arrangements using silicon nanowires are described.
Abstract translation: 描述了使用硅纳米线制造自对准异质结构和半导体布置的方法。
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公开(公告)号：US20180277329A1
公开(公告)日：2018-09-27
申请号：US15987645
申请日：2018-05-23
Applicant: California Institute of Technology
Inventor： Axel SCHERER , William M. JONES , Danil M. LUKIN , Sameer WALAVALKAR , Chieh-feng CHANG
CPC classification number: H01J19/24 , H01J9/025 , H01J21/02 , H01J21/105 , H01J2209/0223
Abstract: Nanoscale field-emission devices are presented, wherein the devices include at least a pair of electrodes separated by a gap through which field emission of electrons from one electrode to the other occurs. The gap is dimensioned such that only a low voltage is required to induce field emission. As a result, the emitted electrons energy that is below the ionization potential of the gas or gasses that reside within the gap. In some embodiments, the gap is small enough that the distance between the electrodes is shorter than the mean-free path of electrons in air at atmospheric pressure. As a result, the field-emission devices do not require a vacuum environment for operation.
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公开(公告)号：US20150268191A1
公开(公告)日：2015-09-24
申请号：US14673700
申请日：2015-03-30
Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
Inventor： Andrew P. HOMYK , Michael D. HENRY , Axel SCHERER , Sameer WALAVALKAR
IPC: G01N27/414 , H01L29/06 , H01L29/66
CPC classification number: G01N27/4146 , B82Y10/00 , B82Y15/00 , H01L29/0676 , H01L29/66666 , H01L29/775
Abstract: Methods for fabricating silicon nanowire chemical sensing devices, devices thus obtained, and methods for utilizing devices for sensing and measuring chemical concentration of selected species in a fluid are described. Devices may comprise a metal-oxide-semiconductor field-effect transistor (MOSFET) structure.
Abstract translation: 描述了制造硅纳米线化学感测装置的方法，如此获得的装置，以及利用用于感测和测量流体中选定物种的化学浓度的装置的方法。 器件可以包括金属氧化物半导体场效应晶体管（MOSFET）结构。
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Patent Agency Ranking
6.发明申请公开(公告)号：US20180243720A1
公开(公告)日：2018-08-30
申请号：US15967543
申请日：2018-04-30
Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
Inventor： Sameer WALAVALKAR , Axel SCHERER
CPC classification number: B01J19/0046 , B01J2219/00585 , C12Q1/689 , C12Q2600/158 , G01N21/65 , G01N21/658
Abstract: Methods and systems for nanopillar sensors are described. Nanopillars can be defined on a substrate, and metal deposited on the nanopillars. A thermal treatment can reflow the metal on the nanopillars forming metallic bulbs on the top end of the nanopillars. These structures can have enhanced optical detection when functionalized with biological agents, or can detect gases, particles and liquids through interaction with the metal layer on the nanopillars.
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公开(公告)号：US20170250048A1
公开(公告)日：2017-08-31
申请号：US15442408
申请日：2017-02-24
Applicant: California Institute of Technology
Inventor： Axel SCHERER , William M. JONES , Danil M. LUKIN , Sameer WALAVALKAR , Chieh-feng CHANG
CPC classification number: H01J19/24 , H01J9/025 , H01J21/02 , H01J21/105 , H01J2209/0223
Abstract: Nanoscale field-emission devices are presented, wherein the devices include at least a pair of electrodes separated by a gap through which field emission of electrons from one electrode to the other occurs. The gap is dimensioned such that only a low voltage is required to induce field emission. As a result, the emitted electrons energy that is below the ionization potential of the gas or gasses that reside within the gap. In some embodiments, the gap is small enough that the distance between the electrodes is shorter than the mean-free path of electrons in air at atmospheric pressure. As a result, the field-emission devices do not require a vacuum environment for operation.
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8.发明申请MULTIPLEXED SURFACE ENHANCED RAMAN SENSORS FOR EARLY DISEASE DETECTION AND IN-SITU BACTERIAL MONITORING 有权多功能表面增强拉曼传感器，用于早期疾病检测和现场细菌监测公开(公告)号：US20160067666A1
公开(公告)日：2016-03-10
申请号：US14621306
申请日：2015-02-12
Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
Inventor： Sameer WALAVALKAR , Axel SCHERER
CPC classification number: B01J19/0046 , B01J2219/00585 , C12Q1/689 , C12Q2600/158 , G01N21/65 , G01N21/658
Abstract: Methods and systems for nanopillar sensors are described. Nanopillars can be defined on a substrate, and metal deposited on the nanopillars. A thermal treatment can reflow the metal on the nanopillars forming metallic bulbs on the top end of the nanopillars. These structures can have enhanced optical detection when functionalized with biological agents, or can detect gases, particles and liquids through interaction with the metal layer on the nanopillars.
Abstract translation: 描述了纳米柱传感器的方法和系统。 纳米玻璃可以在基底上定义，金属沉积在纳米柱上。 热处理可以回流纳米柱上的金属，在纳米柱的顶端形成金属灯泡。 这些结构可以在用生物制剂进行功能化时具有增强的光学检测，或者可以通过与纳米柱上的金属层相互作用来检测气体，颗粒和液体。
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公开(公告)号：US20150223739A1
公开(公告)日：2015-08-13
申请号：US14621286
申请日：2015-02-12
Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY , THE REGENTS OF THE UNIVERSITY OF CALIFORNIA , UNIVERSITY OF SOUTHERN CALIFORNIA
Inventor： Sameer WALAVALKAR , Chieh-feng CHANG , Axel SCHERER , Brandon MARIN , Scott E. FRASER
IPC: A61B5/1459 , A61B5/1473 , A61B5/07 , A61B5/00 , H01L27/146 , G01N21/65
CPC classification number: A61B5/1459 , A61B5/0075 , A61B5/076 , A61B5/14735 , A61B5/6848 , A61B5/686 , A61B2562/0233 , A61B2562/0285 , A61B2562/12 , B82Y30/00 , B82Y40/00 , G01N21/658 , H01L27/14698
Abstract: Methods and systems for nanopillar sensors are described. Nanopillars can be defined on a substrate, and metal deposited on the nanopillars. A thermal treatment can reflow the metal on the nanopillars forming metallic bulbs on the top end of the nanopillars. These structures can have enhanced optical detection when functionalized with biological agents, or can detect gases, particles and liquids through interaction with the metal layer on the nanopillars.
Abstract translation: 描述了纳米柱传感器的方法和系统。 纳米玻璃可以在基底上定义，金属沉积在纳米柱上。 热处理可以回流纳米柱上的金属，在纳米柱的顶端形成金属灯泡。 这些结构可以在用生物制剂进行功能化时具有增强的光学检测，或者可以通过与纳米柱上的金属层相互作用来检测气体，颗粒和液体。
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10.发明申请公开(公告)号：US20190126228A1
公开(公告)日：2019-05-02
申请号：US16222865
申请日：2018-12-17
Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
Inventor： Sameer WALAVALKAR , Axel SCHERER
Abstract: Methods and systems for nanopillar sensors are described. Nanopillars can be defined on a substrate, and metal deposited on the nanopillars. A thermal treatment can reflow the metal on the nanopillars forming metallic bulbs on the top end of the nanopillars. These structures can have enhanced optical detection when functionalized with biological agents, or can detect gases, particles and liquids through interaction with the metal layer on the nanopillars.
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