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    MEDICAL DEVICE CHEMICALLY MODIFIED BY PLASMA POLYMERIZATION
    1.
    发明申请
    MEDICAL DEVICE CHEMICALLY MODIFIED BY PLASMA POLYMERIZATION 审中-公开
    通过等离子体聚合改性的医疗器械

    公开(公告)号：US20080245474A1

    公开(公告)日：2008-10-09

    申请号：US12139263

    申请日：2008-06-13

    申请人： Charles D. Claude ,  Jeong S. Lee

    发明人： Charles D. Claude ,  Jeong S. Lee

    IPC分类号： B32B37/02 ,  A61L33/06

    CPC分类号： C08J7/123 ,  A61L29/085 ,  A61L31/10 ,  A61M25/0009 ,  A61M25/0014 ,  A61M25/1027 ,  A61M25/1029 ,  A61M25/1034 ,  B05D1/62 ,  Y10S623/926 ,  Y10T428/26 ,  Y10T428/263 ,  Y10T428/265 ,  Y10T428/31504 ,  Y10T428/3154 ,  Y10T428/31544 ,  Y10T428/31551 ,  Y10T428/31663 ,  Y10T428/31721 ,  Y10T428/31855

    摘要： Medical devices, and particularly intracorporeal devices for therapeutic or diagnostic uses, having a component chemically modified by plasma polymerization. The medical device comprises a substrate with a plasma polymerized functionality bonded to a surface of at least a section thereof. The plasma polymerized film on a first component of the medical device allows for bonding an agent or a second component to the first component. In one embodiment, the plasma polymerized film facilitates fusion or adhesive bonding of a first component to a second component formed of a material which is dissimilar to, incompatible with, or otherwise not readily bondable to the substrate material of the first component. In another embodiment, a bioactive agent is bonded to the plasma polymerized film on the component, for presenting or delivering the bioactive agent within a body lumen of the patient.

    摘要翻译： 医疗装置，特别是用于治疗或诊断用途的体内装置，其具有通过等离子体聚合化学改性的组分。 医疗装置包括具有等离子体聚合功能性的基底，其结合至少部分的表面。 医疗装置的第一部件上的等离子体聚合膜允许将试剂或第二组分粘合到第一组分。 在一个实施方案中，等离子体聚合膜促进第一组分与由与第一组分的衬底材料不相容，不相容或不容易粘合的材料形成的第二组分的熔融或粘合。 在另一个实施方案中，生物活性剂与组分上的等离子体聚合膜结合，用于在患者的体腔内呈递或递送生物活性剂。

    Medical device chemically modified by plasma polymerization
    2.
    发明授权
    Medical device chemically modified by plasma polymerization 有权
    通过等离子体聚合法化学修饰的医疗器械

    公开(公告)号：US07396582B2

    公开(公告)日：2008-07-08

    申请号：US09827887

    申请日：2001-04-06

    申请人： Charles D. Claude ,  Jeong S. Lee

    发明人： Charles D. Claude ,  Jeong S. Lee

    IPC分类号： B32B27/32 ,  B32B27/00 ,  A61M5/32 ,  A61M29/00

    CPC分类号： C08J7/123 ,  A61L29/085 ,  A61L31/10 ,  A61M25/0009 ,  A61M25/0014 ,  A61M25/1027 ,  A61M25/1029 ,  A61M25/1034 ,  B05D1/62 ,  Y10S623/926 ,  Y10T428/26 ,  Y10T428/263 ,  Y10T428/265 ,  Y10T428/31504 ,  Y10T428/3154 ,  Y10T428/31544 ,  Y10T428/31551 ,  Y10T428/31663 ,  Y10T428/31721 ,  Y10T428/31855

    摘要： Medical devices, and particularly intracorporeal devices for therapeutic or diagnostic uses, having a component chemically modified by plasma polymerization. The medical device comprises a substrate with a plasma polymerized functionality bonded to a surface of at least a section thereof. The plasma polymerized film on a first component of the medical device allows for bonding an agent or a second component to the first component. In one embodiment, the plasma polymerized film facilitates fusion or adhesive bonding of a first component to a second component formed of a material which is dissimilar to, incompatible with, or otherwise not readily bondable to the substrate material of the first component. In another embodiment, a bioactive agent is bonded to the plasma polymerized film on the component, for presenting or delivering the bioactive agent within a body lumen of the patient.

    摘要翻译： 医疗装置，特别是用于治疗或诊断用途的体内装置，其具有通过等离子体聚合化学改性的组分。 医疗装置包括具有等离子体聚合功能性的基底，其结合至少部分的表面。 医疗装置的第一部件上的等离子体聚合膜允许将试剂或第二组分粘合到第一组分。 在一个实施方案中，等离子体聚合膜促进第一组分与由与第一组分的衬底材料不相容，不相容或不容易粘合的材料形成的第二组分的熔融或粘合。 在另一个实施方案中，生物活性剂与组分上的等离子体聚合膜结合，用于在患者的体腔内呈递或递送生物活性剂。

    Catheter with a multilayered shaft section having a polyimide layer
    4.
    发明授权
    Catheter with a multilayered shaft section having a polyimide layer 有权

    公开(公告)号：US09855400B2

    公开(公告)日：2018-01-02

    申请号：US12477695

    申请日：2009-06-03

    申请人： Jeong S. Lee ,  Edwin Wang ,  Roseminda J. White

    发明人： Jeong S. Lee ,  Edwin Wang ,  Roseminda J. White

    IPC分类号： A61M29/00 ,  A61M25/00 ,  A61L29/08 ,  A61M25/10

    CPC分类号： A61M25/0045 ,  A61L29/085 ,  A61M25/0009 ,  A61M25/104 ,  C08L77/12 ,  C08L75/04 ,  C08L79/08

    摘要： A catheter having an multilayered shaft section with a first layer formed of a polyimide first material and a second layer formed of a second material. In a presently preferred embodiment, the polyimide material is a thermoset polyimide. However, in alternative embodiments, a thermoplastic polyimide is used. The thermoset polyimide has a very high glass transition temperature (Tg) of approximately 400° C. (as measured by differential scanning calorimetry), and excellent dimensional stability at the processing temperature of polyamides commonly used in catheter components. As a result, during formation and assembly of the catheter, production of a thin polyimide layer with controlled dimensions is facilitated. The polyimide has a high modulus and provides a thin walled yet highly pushable shaft section, while the second layer provides kink resistance. In one embodiment, the second material is selected from the group consisting of a polyamide material and a polyurethane material.

    RAPID EXCHANGE INFUSION CATHETER
    8.
    发明申请
    RAPID EXCHANGE INFUSION CATHETER 审中-公开
    快速交换输液管

    公开(公告)号：US20120053565A1

    公开(公告)日：2012-03-01

    申请号：US13231820

    申请日：2011-09-13

    申请人： Jeong S. Lee

    发明人： Jeong S. Lee

    IPC分类号： A61M25/10

    CPC分类号： A61M25/10 ,  A61M2025/0183

    摘要： An infusion catheter and method, with an elongated shaft having a guidewire lumen which has a proximal section and a common distal section extending to a distal port at a distal end of the shaft, and an infusion lumen which is in fluid communication with the distal port of the guidewire lumen and which joins the common distal section of the guidewire lumen at a location distal to the guidewire proximal port. A restricted passage from the infusion lumen to the common distal section of the guidewire lumen has a smaller transverse dimension than the guidewire lumen and a guidewire slidably disposed in the guidewire lumen.

    摘要翻译： 一种输注导管和方法，其具有细长轴，所述细长轴具有导丝管腔，所述导丝管腔具有延伸到所述轴的远端处的远端端口的近端部分和共同远端部分，以及与所述远端端口流体连通的输注内腔 并且其在导丝内腔的公共远端部分在远离导丝近端口的位置处连接。 从输液腔到导线管腔的共同远端部分的限制通道具有比导丝管腔更小的横向尺寸和可滑动地设置在导丝管腔内的导丝。

    Rapid exchange infusion catheter
    9.
    发明授权
    Rapid exchange infusion catheter 有权
    快速交换输液导管

    公开(公告)号：US08021328B2

    公开(公告)日：2011-09-20

    申请号：US11682104

    申请日：2007-03-05

    申请人： Jeong S. Lee

    发明人： Jeong S. Lee

    IPC分类号： A61M29/00

    CPC分类号： A61M25/10 ,  A61M2025/0183

    摘要： An infusion catheter and method, with an elongated shaft having a guidewire lumen which has a proximal section and a common distal section extending to a distal port at a distal end of the shaft, and an infusion lumen which is in fluid communication with the distal port of the guidewire lumen and which joins the common distal section of the guidewire lumen at a location distal to the guidewire proximal port. A restricted passage from the infusion lumen to the common distal section of the guidewire lumen has a smaller transverse dimension than the guidewire lumen and a guidewire slidably disposed in the guidewire lumen.

    摘要翻译： 一种输注导管和方法，其具有细长轴，所述细长轴具有导丝管腔，所述导丝管腔具有延伸到所述轴的远端处的远端端口的近端部分和共同远端部分，以及与所述远端端口流体连通的输注内腔 并且其在导丝内腔的公共远端部分在远离导丝近端口的位置处连接。 从输液腔到导线管腔的共同远端部分的限制通道具有比导丝管腔更小的横向尺寸和可滑动地设置在导丝管腔内的导丝。

    Catheter with optical fiber sensor
    10.
    发明授权
    Catheter with optical fiber sensor 有权
    导管与光纤传感器

    公开(公告)号：US07783338B2

    公开(公告)日：2010-08-24

    申请号：US12008381

    申请日：2008-01-09

    申请人： Robert Ainsworth ,  Deborah Kilpatrick ,  Jeong S. Lee ,  Bridget A. Hurley ,  Jeffrey T. Ellis

    发明人： Robert Ainsworth ,  Deborah Kilpatrick ,  Jeong S. Lee ,  Bridget A. Hurley ,  Jeffrey T. Ellis

    IPC分类号： A61B5/00

    CPC分类号： A61B5/0084 ,  A61B5/0086 ,  A61B5/02007 ,  A61B5/02154 ,  A61B5/1459 ,  A61B5/6853 ,  A61B2017/22001

    摘要： An apparatus and method to perform therapeutic treatment and diagnosis of a patient's vasculature through the use of an intravascular device having an optical fiber disposed therein. In an embodiment, the apparatus includes an intravascular device to perform a therapeutic treatment and at least one optical fiber disposed through the intravascular device. The optical fiber is configured to provide diagnostic information before, during, and after the therapeutic treatment. In an embodiment, diagnostic information includes vessel and blood characteristics such as hemodynamic characteristics, hematological parameters related to blood and blood components, and thermal parameters of the vasculature.

    摘要翻译： 通过使用其中设置有光纤的血管内装置来对患者的脉管系统进行治疗处理和诊断的装置和方法。 在一个实施例中，该装置包括执行治疗性处理的血管内装置和通过血管内装置设置的至少一个光纤。 光纤被配置为在治疗之前，期间和之后提供诊断信息。 在一个实施方案中，诊断信息包括血管和血液特征，例如血液动力学特征，与血液和血液成分有关的血液学参数，以及脉管系统的热参数。