BIOCHIP AND METHOD OF DETECTING REACTION FROM THE SAME
    1.
    发明申请
    BIOCHIP AND METHOD OF DETECTING REACTION FROM THE SAME 审中-公开
    检测反应物的生物学和方法

    公开(公告)号:US20110091905A1

    公开(公告)日:2011-04-21

    申请号:US12893166

    申请日:2010-09-29

    CPC分类号: G01N33/5302 G01N21/31

    摘要: Provided are a biochip and a method of detecting a reaction from the biochip. This method includes preparing a first mixture solution of polyvinylpyrrolidone (PVP) and a sample including target molecules, measuring absorbance or transmittance of the first mixture solution, preparing a second mixture solution including the PVP, the sample, and a receptor of the target molecules, measuring absorbance or transmittance of the second mixture solution, and calculating an absorbance or transmittance difference between the first mixture solution and the second mixture solution. Thus, it is possible to reduce the production cost of the biochip by inducing a reaction of an antigen and an antibody using PVP. Further, it is possible to detect an accurate quantity of the antigen by analyzing a quantity of antigen on the basis of the absorbance or transmittance difference.

    摘要翻译: 提供了一种生物芯片和从生物芯片检测反应的方法。 该方法包括制备聚乙烯吡咯烷酮(PVP)的第一混合溶液和包含靶分子的样品,测量第一混合溶液的吸光度或透射率,制备包含PVP,样品和靶分子的受体的第二混合溶液, 测量第二混合溶液的吸光度或透射率,并计算第一混合溶液和第二混合溶液之间的吸光度或透射率差异。 因此,通过使用PVP诱导抗原和抗体的反应,可以降低生物芯片的生产成本。 此外,可以通过基于吸光度或透射率差异分析抗原量来检测精确量的抗原。

    LABEL-FREE BIOSENSOR
    2.
    发明申请
    LABEL-FREE BIOSENSOR 审中-公开
    无标签生物传感器

    公开(公告)号:US20120141327A1

    公开(公告)日:2012-06-07

    申请号:US13283477

    申请日:2011-10-27

    IPC分类号: G01N21/75

    CPC分类号: G01N21/7703

    摘要: A label-free biosensor includes a substrate, a reaction inducing part for inducing a bio antigen-antibody reaction to occur, and a reaction detecting part formed on the substrate and adapted to measure current change in accordance with change in an amount of light, which is caused by the bio antigen-antibody reaction in the reaction inducing part, to detect a bio antigen.

    摘要翻译: 无标记的生物传感器包括底物,用于诱导生物抗原 - 抗体反应发生的反应诱导部分,以及反应检测部分,其形成在基板上并且适于根据光量的变化来测量电流变化, 是由反应诱导部分的生物抗原 - 抗体反应引起的,以检测生物抗原。

    PHOTONIC BIOSENSOR, PHOTONIC BIOSENSOR ARRAY, AND METHOD OF DETECTING BIOMATERIALS USING THE SAME
    3.
    发明申请
    PHOTONIC BIOSENSOR, PHOTONIC BIOSENSOR ARRAY, AND METHOD OF DETECTING BIOMATERIALS USING THE SAME 审中-公开
    光电生物传感器,光电生物传感器阵列,以及使用该方法检测生物体的方法

    公开(公告)号:US20110129846A1

    公开(公告)日:2011-06-02

    申请号:US12860796

    申请日:2010-08-20

    摘要: A photonic biosensor, a photonic biosensor array, and a method of detecting a bio-material using the same are provided. The photonic biosensor includes a light emitting diode configured to emit light, a photodiode (PD), an optical fiber configured to connect the light emitting diode with the PD, and a micro-fluidic channel disposed on the optical fiber. Bio-antibodies or aptamers are fixed to the surface of the optical fiber, and the micro-fluidic channel includes gold (Au) nanoparticles to which bio-antibodies or aptamers are fixed. The photonic biosensor may be configured using absorption of surface plasmons in Au nanoparticles with respect to light traveling through the surface of the optical fiber configured to connect the light emitting diode with the PD, thus simplifying the manufacture of the biosensor and reducing the manufacturing cost.

    摘要翻译: 提供了光子生物传感器,光子生物传感器阵列和使用其的生物材料的检测方法。 光子生物传感器包括被配置为发光的发光二极管,光电二极管(PD),被配置为将发光二极管与PD连接的光纤以及设置在光纤上的微流体通道。 生物抗体或适配体固定在光纤表面,微流体通道包括固定有生物抗体或适体的金(Au)纳米颗粒。 光子生物传感器可以使用Au纳米颗粒中的表面等离子体的吸收来配置,该光束传播通过配置成将发光二极管与PD连接的光纤的表面传播的光,从而简化了生物传感器的制造并降低了制造成本。

    SILICON BIOSENSOR AND MANUFACTURING METHOD THEREOF
    5.
    发明申请
    SILICON BIOSENSOR AND MANUFACTURING METHOD THEREOF 审中-公开
    硅生物传感器及其制造方法

    公开(公告)号:US20100278694A1

    公开(公告)日:2010-11-04

    申请号:US12746247

    申请日:2008-06-20

    IPC分类号: G01N21/00 H01L21/70

    CPC分类号: G01N33/54366

    摘要: A silicon biosensor and a manufacturing method thereof is provided, the silicon biosensor includes: a light source performing self emission a light detector generating a photoelectric current corresponding to an amount of incident light an optical fiber transmitting the light from the light source to the light detector and a micro fluidic channel adjusting an optical transmission rate of the optical fiber according to an antibody-antigen reaction when the antibody-antigen reaction occurs. The silicon biosensor can be easily integrated or bonded with a silicon electronic device, so that it is possible to manufacture the biosensor with a low price, under mass production.

    摘要翻译: 提供硅生物传感器及其制造方法,所述硅生物传感器包括:光源,其进行自发光,所述光检测器产生与入射光量相对应的光电流,所述光传输光从所述光源传输到所述光检测器 以及当发生抗体 - 抗原反应时根据抗体 - 抗原反应调节光纤的光传输速率的微流体通道。 硅生物传感器可以容易地与硅电子器件集成或结合,使得可以在批量生产的情况下以低价格制造生物传感器。

    APPARATUS FOR FIXING PLASTIC SHEET AND METHOD OF FABRICATING NANO PATTERN ON PLASTIC SHEET USING THE SAME
    8.
    发明申请
    APPARATUS FOR FIXING PLASTIC SHEET AND METHOD OF FABRICATING NANO PATTERN ON PLASTIC SHEET USING THE SAME 有权
    用于固定塑料片的装置和使用其制造塑料片上的纳米图案的方法

    公开(公告)号:US20100264567A1

    公开(公告)日:2010-10-21

    申请号:US12743117

    申请日:2008-05-21

    IPC分类号: B29C59/16

    摘要: There are provided an apparatus for fixing a plastic sheet which fixes a plastic sheet to fabricate a nano pattern and a method of fabricating a nano pattern on a plastic sheet using the same. The apparatus for fixing a plastic sheet includes: a pair of planar metal guide rings interposingly fixing a plastic sheet from above and below, respectively; and a sheet fixing chuck including: a ring fixer sucking the pair of planar metal guide rings through a vacuum groove to be fixed thereto; and a sheet fixer having a plurality of vacuum pin holes formed therein, the vacuum pin holes sucking a bottom of the plastic sheet fixed by the planar metal guide rings. The apparatus allows fabrication of the nano pattern on the plastic sheet having less roughness than that of a semiconductor substrate or a glass substrate.

    摘要翻译: 提供了一种用于固定塑料片以制造纳米图案的塑料片的设备和使用其形成在塑料片上的纳米图案的方法。 用于固定塑料片的装置包括:分别从上下固定塑料片的一对平面金属导向环; 以及片状固定卡盘,其包括:环形固定器,其通过真空槽吸附所述一对平面金属导向环以固定到其上; 以及具有形成在其中的多个真空针孔的片固定器,所述真空针孔吸附由所述平面金属导向环固定的所述塑料片的底部。 该装置允许在塑料片上制造具有比半导体衬底或玻璃衬底更小的粗糙度的纳米图案。

    Apparatus for fixing plastic sheet and method of fabricating nano pattern on plastic sheet using the same
    10.
    发明授权
    Apparatus for fixing plastic sheet and method of fabricating nano pattern on plastic sheet using the same 有权
    用于固定塑料片的装置和使用其制造在塑料片上的纳米图案的方法

    公开(公告)号:US08292608B2

    公开(公告)日:2012-10-23

    申请号:US12743117

    申请日:2008-05-21

    IPC分类号: B29C43/32

    摘要: There are provided an apparatus for fixing a plastic sheet which fixes a plastic sheet to fabricate a nano pattern and a method of fabricating a nano pattern on a plastic sheet using the same. The apparatus for fixing a plastic sheet includes: a pair of planar metal guide rings interposingly fixing a plastic sheet from above and below, respectively; and a sheet fixing chuck including: a ring fixer sucking the pair of planar metal guide rings through a vacuum groove to be fixed thereto; and a sheet fixer having a plurality of vacuum pin holes formed therein, the vacuum pin holes sucking a bottom of the plastic sheet fixed by the planar metal guide rings. The apparatus allows fabrication of the nano pattern on the plastic sheet having less roughness than that of a semiconductor substrate or a glass substrate.

    摘要翻译: 提供了一种用于固定塑料片以制造纳米图案的塑料片的设备和使用其形成在塑料片上的纳米图案的方法。 用于固定塑料片的装置包括:分别从上下固定塑料片的一对平面金属导向环; 以及片状固定卡盘,其包括:环形固定器,其通过真空槽吸附所述一对平面金属导向环以固定到其上; 以及具有形成在其中的多个真空针孔的片固定器,所述真空针孔吸附由所述平面金属导向环固定的所述塑料片的底部。 该装置允许在塑料片上制造具有比半导体衬底或玻璃衬底更小的粗糙度的纳米图案。