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公开(公告)号：US20180078701A1
公开(公告)日：2018-03-22
申请号：US15826918
申请日：2017-11-30
申请人： Consort Medical PLC.
发明人： Ian Anderson , Matt Ekman
IPC分类号： A61M3/02 , A61M15/00 , B05B11/00 , A61M15/08 , A61M31/00 , B05B7/24 , B05B11/02 , A61M39/24 , A61M11/00 , A61M5/31
CPC分类号： A61M3/0279 , A61M11/007 , A61M15/0028 , A61M15/003 , A61M15/0043 , A61M15/08 , A61M31/00 , A61M39/24 , A61M2005/3128 , A61M2039/242 , A61M2202/0468 , A61M2210/0618 , B05B7/24 , B05B11/007 , B05B11/02
摘要： A valved container assembly comprising a container for containing a fluid, the container extending in an axial direction and having an open front end, a valve disposed in the container; and a plunger element disposed axially rearward of the valve. The plunger element is axially moveable in the container and a first volume is provided in the container between the plunger element and the valve, wherein the plunger element is configured to increase a pressure of the fluid in the first volume upon axial movement of the plunger element relative to the valve. The valve comprises a seal fluidly sealing the valve to an interior of the container along an entire perimeter of the valve, and a channel bypassing the seal, the channel having a first opening in fluid communication with an atmosphere outside of the valved container assembly and a second opening selectively sealed from the first volume by a resilient seal. The resilient seal is moveable between a sealing configuration and an open configuration to selectively seal the channel from the first volume, wherein in the sealing configuration the resilient seal fluidly seals against the container to fluidly seal the valve to the container so as to fluidly isolate the channel from the first volume, and in the open configuration the resilient seal does not fluidly seal against the container to fluidly seal the valve to the container so that the second opening of the channel is in fluid communication with the first volume. The resilient seal is moveable from the sealing configuration to the open configuration upon the pressure of the fluid in the first volume exceeding a first pressure threshold.
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公开(公告)号：US20150144127A1
公开(公告)日：2015-05-28
申请号：US14405271
申请日：2013-06-14
申请人： CONSORT MEDICAL PLC
发明人： Matt Ekman , Ian Anderson
CPC分类号： A61M39/24 , A61M5/2459 , A61M11/007 , A61M11/065 , A61M15/0028 , A61M15/08 , A61M2039/242 , A61M2205/8225 , A61M2205/8231 , A61M2207/00 , A61M2210/0618 , B05B11/0054 , B05B11/007 , B05B11/02 , B05C17/00593 , B65D83/0005 , Y10T29/4984
摘要： A valved container assembly (10) comprising a container (12) for containing a fluid, the container (12) extending in an axial direction and having at least one venting opening (12a) at a front end and at least one dispensing opening (12b). The valved container assembly (10) further comprising a valve (14) disposed in the container (12) and a plunger element (20) disposed axially rearward of the valve (14), the plunger element (20) being axially moveable in the container (12) and defining a first volume (22) in the container (12) between the plunger element (20) and the valve (14), where the plunger element (20) is configured to increase the pressure of a fluid in the first volume (22) upon axial movement relative to the valve (14). The valve (14) comprises a permanent seal (16) forming a fluidic seal between the at least one venting opening (12a) and the first volume (22), and a resilient seal (18) that is axially rearward of said permanent seal (16) and is moveable between a sealing configuration and an open configuration. In the sealing configuration the resilient seal (18) forms a fluidic seal with the container (12) between the at least one dispensing opening (12b) and the first volume (22). In at least one axial position of the valve (14) in the container (12) when the resilient seal (18) is in the open configuration the first volume (22) is fluidly connected to the at least one dispensing opening (12b). The resilient seal (18) is moveable from the sealing configuration to the open configuration upon fluid pressure in the first volume (22) exceeding a predetermined pressure threshold.
摘要翻译： 一种阀的容器组件（10），包括用于容纳流体的容器（12），所述容器（12）在轴向方向上延伸并且在前端具有至少一个通气开口（12a）和至少一个分配开口（12b ）。 带阀的容器组件（10）还包括设置在容器（12）中的阀（14）和设置在阀（14）的轴向后方的柱塞元件（20），柱塞元件（20）可在容器 （12）并且在所述柱塞元件（20）和所述阀（14）之间的所述容器（12）中限定第一容积（22），其中所述柱塞元件（20）构造成增加所述第一 相对于阀（14）在轴向移动时的体积（22）。 所述阀（14）包括在所述至少一个通气开口（12a）和所述第一容积（22）之间形成流体密封件的永久性密封件（16）和位于所述永久密封件的轴向后方的弹性密封件（18） 16），并且可以在密封构造和打开构型之间移动。 在密封构造中，弹性密封件（18）与至少一个分配开口（12b）和第一容积（22）之间的容器（12）形成流体密封。 当弹性密封件（18）处于打开构造时，在容器（12）中的阀（14）的至少一个轴向位置中，第一容积（22）流体地连接到至少一个分配开口（12b）。 当第一容积（22）中的流体压力超过预定压力阈值时，弹性密封件（18）可以从密封构型移动到打开构型。
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公开(公告)号：US10646639B2
公开(公告)日：2020-05-12
申请号：US15826918
申请日：2017-11-30
申请人： Consort Medical PLC
发明人： Ian Anderson , Matt Ekman
IPC分类号： A61M3/02 , A61M15/00 , A61M15/08 , B05B11/00 , B05B11/02 , A61M31/00 , A61M39/24 , B05B7/24 , A61M5/31 , A61M11/00
摘要： A valved container assembly has a container for containing a fluid, extending in an axial direction, and having an open front end and a valve disposed in the container. A plunger element is disposed axially rearward of the valve and is axially moveable in the container. The plunger element is configured to increase the pressure of a fluid in a first volume of the container upon axial movement of the plunger element relative to the valve. The valve includes a channel bypassing a seal, the channel having a first opening in fluid communication with the atmosphere outside of the valved container assembly and a second opening selectively sealed from the first volume by a resilient seal. The resilient seal is moveable from a sealing configuration to an open configuration upon the pressure of the fluid in the first volume exceeding a first pressure threshold.
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公开(公告)号：US10080882B2
公开(公告)日：2018-09-25
申请号：US14405271
申请日：2013-06-14
申请人： CONSORT MEDICAL PLC
发明人： Matt Ekman , Ian Anderson
IPC分类号： A61M11/00 , A61M39/24 , A61M15/00 , B05B11/00 , B05B11/02 , B65D83/00 , A61M15/08 , A61M11/06 , B05C17/005 , A61M5/24
CPC分类号： A61M39/24 , A61M5/2459 , A61M11/007 , A61M11/065 , A61M15/0028 , A61M15/08 , A61M2039/242 , A61M2205/8225 , A61M2205/8231 , A61M2207/00 , A61M2210/0618 , B05B11/0054 , B05B11/007 , B05B11/02 , B05C17/00593 , B65D83/0005 , Y10T29/4984
摘要： A valved container assembly (10) comprising a container (12) for containing a fluid, the container (12) extending in an axial direction and having at least one venting opening (12a) at a front end and at least one dispensing opening (12b). The valved container assembly (10) further comprising a valve (14) disposed in the container (12) and a plunger element (20) disposed axially rearward of the valve (14), the plunger element (20) being axially moveable in the container (12) and defining a first volume (22) in the container (12) between the plunger element (20) and the valve (14), where the plunger element (20) is configured to increase the pressure of a fluid in the first volume (22) upon axial movement relative to the valve (14). The valve (14) comprises a permanent seal (16) forming a fluidic seal between the at least one venting opening (12a) and the first volume (22), and a resilient seal (18) that is axially rearward of said permanent seal (16) and is moveable between a sealing configuration and an open configuration. In the sealing configuration the resilient seal (18) forms a fluidic seal with the container (12) between the at least one dispensing opening (12b) and the first volume (22). In at least one axial position of the valve (14) in the container (12) when the resilient seal (18) is in the open configuration the first volume (22) is fluidly connected to the at least one dispensing opening (12b). The resilient seal (18) is moveable from the sealing configuration to the open configuration upon fluid pressure in the first volume (22) exceeding a predetermined pressure threshold.
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公开(公告)号：US09833558B2
公开(公告)日：2017-12-05
申请号：US14380241
申请日：2013-02-22
申请人： CONSORT MEDICAL PLC
发明人： Ian Anderson , Matt Ekman
IPC分类号： A61M3/02 , A61M15/00 , A61M15/08 , B05B11/00 , B05B11/02 , A61M31/00 , A61M39/24 , B05B7/24 , A61M5/31 , A61M11/00
CPC分类号： A61M3/0279 , A61M11/007 , A61M15/0028 , A61M15/003 , A61M15/0043 , A61M15/08 , A61M31/00 , A61M39/24 , A61M2005/3128 , A61M2039/242 , A61M2202/0468 , A61M2210/0618 , B05B7/24 , B05B11/007 , B05B11/02
摘要： A valved container assembly which has a container for containing a fluid, the container extending in an axial direction and having an open front end and a valve disposed in the container. The valved container assembly is configured so that forward axial movement of the valve relative to the container is inhibited. A plunger element is disposed axially rearward of the valve and is axially moveable in the container. The plunger element is configured to increase the pressure of a fluid in a first volume of the container upon forward axial movement relative to the valve. The valve includes a channel bypassing the permanent seal, the channel having a first opening in fluid communication with the atmosphere outside of the valved container assembly and a second opening selectively sealed from the first volume by a resilient seal.
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公开(公告)号：US20160279341A1
公开(公告)日：2016-09-29
申请号：US14777885
申请日：2014-03-26
申请人： CONSORT MEDICAL PLC
发明人： Ian Anderson , Matt Ekman , Robert Glover , Rachel Koppelman
CPC分类号： A61M5/31596 , A61M5/3137 , A61M5/31505
摘要： A syringe assembly comprising a barrel for containing one or more medicaments, the barrel having a front outlet for allowing the expulsion of said one or more medicaments from the said barrel through said outlet, and a first stopper disposed in the barrel and axially moveable therein and defining a first volume in the barrel axially forwards of the first stopper and a second volume in the barrel axially rearwards of the first stopper. The first stopper has a two way valve that is moveable between a sealing configuration and an open configuration to selectively put the first volume in fluid communication with the second volume. The two way valve is moveable from the sealing configuration to the open configuration by an increase in fluid pressure in either of the first and second volumes. The syringe assembly additionally comprises a second stopper disposed in the barrel axially rearward of the first stopper and axially moveable therein, the second stopper providing a fluid tight seal at a rear end of the second volume. The syringe assembly further comprises a first plunger rod connected to the first stopper and extending axially rearwardly through the second stopper, the second stopper sealingly engaging with the first plunger rod but permitting axial sliding of the first plunger rod therethrough. The first plunger rod is axially moveable so as to axially move the first stopper and pressurise either of the first volume and second volume causing the two way valve to move into the open configuration and fluidly connect the first volume and second volume.
摘要翻译： 一种注射器组件，包括用于容纳一种或多种药物的镜筒，所述镜筒具有前出口，用于允许所述一个或多个药物从所述镜筒通过所述出口排出;以及第一止动件，其设置在所述镜筒中并在其中可轴向移动; 限定所述筒体中的第一容积在所述第一止动件的轴向前方，所述筒体中的第二容积在所述第一止动件的轴向向后。 第一止动器具有可在密封构造和打开构型之间移动的双向阀，以选择性地将第一容积与第二容积流体连通。 双向阀可以通过在第一和第二体积中的任一个中的流体压力的增加从密封构造移动到打开构造。 注射器组件还包括设置在筒体中的第一止动件的轴向后方并在其中可轴向移动的第二止动件，第二止动件在第二容积的后端提供流体密封。 注射器组件还包括连接到第一止动件并且轴向向后延伸穿过第二止动件的第一柱塞杆，第二止动件与第一柱塞杆密封地接合，但允许第一柱塞杆通过其轴向滑动。 第一柱塞杆可轴向移动以便轴向移动第一止动件并对第一容积和第二容积中的任何一个进行加压，从而使双向阀移动到打开构型中并且流体地连接第一容积和第二容积。
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公开(公告)号：US20150141918A1
公开(公告)日：2015-05-21
申请号：US14406171
申请日：2013-06-07
申请人： CONSORT MEDICAL PLC
CPC分类号： B65D83/24 , A61M5/142 , A61M5/14526 , A61M5/155 , A61M5/16804 , A61M5/16881 , A61M5/2053 , A61M5/44 , A61M39/22 , A61M2005/14513 , A61M2039/2486 , A61M2207/00 , A61M2207/10 , B65B31/045 , B65B51/26 , B65B51/30 , F04C2270/0421 , Y10T29/49 , Y10T29/49808
摘要： A syringe propellable by propellant that boils at a predetermined temperature, the syringe including a barrel having an outlet at a front end, and a stopper axially moveable in the barrel. The stopper separates a first chamber and a second chamber, the first chamber being axially forwards of the stopper and being configured for containing a medicament, and the second chamber being axially rearwards of the stopper and being configured to receive propellant for acting on the stopper to move the stopper axially forwardly in the barrel to expel medicament through the outlet upon actuation of the syringe. The syringe further includes a rupturing portion and a third chamber for containing propellant where the third chamber is rupturable upon actuation of the syringe to fluidly connect the third chamber to the second chamber. When propellant is released into the second chamber the pressure in the second chamber increases causing the stopper to move axially forwardly to begin expulsion of medicament from the first chamber through the outlet. The syringe is configured such that while the medicament is expelled from the first chamber the pressure in the second chamber changes to a second pressure.
摘要翻译： 由推进剂推动的注射器在预定温度下沸腾的注射器，注射器包括在前端具有出口的筒体和在筒体中可轴向移动的止动件。 塞子分离第一腔室和第二腔室，第一腔室位于塞子的轴向前方并被构造用于容纳药物，第二腔室位于塞子的轴向后方，并且构造成容纳用于作用在塞子上的推进剂 在塞子的轴向向前移动塞子，以在注射器致动时通过出口排出药物。 注射器还包括破裂部分和用于容纳推进剂的第三腔室，其中第三腔室在注射器致动时可破裂，以将第三腔室流体连接到第二腔室。 当推进剂被释放到第二室中时，第二室中的压力增加，使得塞子轴向向前移动以开始通过出口将药物从第一室排出。 注射器构造成使得当药物从第一腔室排出时，第二腔室中的压力变为第二压力。
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公开(公告)号：US20220054762A1
公开(公告)日：2022-02-24
申请号：US17519627
申请日：2021-11-05
申请人： CONSORT MEDICAL PLC
发明人： Ian Anderson , Matt Ekman , Robert Glover , Rachel Koppelman
摘要： A syringe assembly comprising a barrel for containing one or more medicaments, the barrel having a front outlet for allowing the expulsion of said one or more medicaments from the said barrel through said outlet, and a first stopper disposed in the barrel and axially moveable therein and defining a first volume in the barrel axially forwards of the first stopper and a second volume in the barrel axially rearwards of the first stopper. The first stopper has a two way valve that is moveable between a sealing configuration and an open configuration to selectively put the first volume in fluid communication with the second volume. The two way valve is moveable from the sealing configuration to the open configuration by an increase in fluid pressure in either of the first and second volumes. The syringe assembly additionally comprises a second stopper disposed in the barrel axially rearward of the first stopper and axially moveable therein, the second stopper providing a fluid tight seal at a rear end of the second volume. The syringe assembly further comprises a first plunger rod connected to the first stopper and extending axially rearwardly through the second stopper, the second stopper sealingly engaging with the first plunger rod but permitting axial sliding of the first plunger rod therethrough. The first plunger rod is axially moveable so as to axially move the first stopper and pressurise either of the first volume and second volume causing the two way valve to move into the open configuration and fluidly connect the first volume and second volume.
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公开(公告)号：US11185637B2
公开(公告)日：2021-11-30
申请号：US14777885
申请日：2014-03-26
申请人： CONSORT MEDICAL PLC
发明人： Ian Anderson , Matt Ekman , Robert Glover , Rachel Koppelman
摘要： A syringe assembly comprising a barrel for containing one or more medicaments, the barrel having a front outlet for allowing the expulsion of said one or more medicaments from the said barrel through said outlet, and a first stopper disposed in the barrel and axially moveable therein and defining a first volume in the barrel axially forwards of the first stopper and a second volume in the barrel axially rearwards of the first stopper. The first stopper has a two way valve that is moveable between a sealing configuration and an open configuration to selectively put the first volume in fluid communication with the second volume. The two way valve is moveable from the sealing configuration to the open configuration by an increase in fluid pressure in either of the first and second volumes. The syringe assembly additionally comprises a second stopper disposed in the barrel axially rearward of the first stopper and axially moveable therein, the second stopper providing a fluid tight seal at a rear end of the second volume. The syringe assembly further comprises a first plunger rod connected to the first stopper and extending axially rearwardly through the second stopper, the second stopper sealingly engaging with the first plunger rod but permitting axial sliding of the first plunger rod therethrough. The first plunger rod is axially moveable so as to axially move the first stopper and pressurise either of the first volume and second volume causing the two way valve to move into the open configuration and fluidly connect the first volume and second volume.
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公开(公告)号：US09962492B2
公开(公告)日：2018-05-08
申请号：US14380334
申请日：2013-02-22
申请人： CONSORT MEDICAL PLC
发明人： Ian Anderson , Matt Ekman
CPC分类号： A61M5/284 , A61M5/2066 , A61M5/286 , A61M5/31596 , A61M5/3294 , A61M2005/1787 , A61M2005/31598
摘要： A syringe assembly having a barrel for containing one or more medicaments and a stopper disposed in the barrel defining and separating a first volume and a second volume within the syringe assembly. The stopper includes a permanent seal fluidly sealing the stopper to the barrel about the entire perimeter of the stopper intermediate the first volume and second volume, and a channel bypassing the permanent seal, the channel having a first opening in fluid communication with the second volume and a second opening selectively sealed from the first volume by a resilient seal. The resilient seal is moveable between a sealing configuration and an open configuration to selectively seal the channel from the first volume and is moveable from the sealing configuration to the open configuration upon fluid pressure in the first volume or second volume exceeding a first pressure threshold.
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