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Patent Agency Ranking
公开(公告)号：US11542300B2
公开(公告)日：2023-01-03
申请号：US15564232
申请日：2016-04-04
Applicant: Cytiva BioProcess R&D AB
Inventor： Martin Hall , Karolina Busson , Jean-Luc Maloisel , Helena Skoglar
IPC: C07K1/18 , B01J41/20 , B01D15/36 , B01D15/38 , A61K38/36 , A61K38/48 , A61K35/16 , C12N9/64 , B01D15/34 , C07K14/47 , C07K14/755 , C07K14/765 , C07K16/00 , A61K38/00
Abstract: The present invention relates to the field of chromatography. More closely, the invention relates to a chromatographic method for purification of plasmaproteins, such as Factor VIII, von Willebrand factor and Factor IX. The chromatographic method is performed on a matrix comprising an inner porous core and outer porous lid surrounding said core.
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公开(公告)号：US11352388B2
公开(公告)日：2022-06-07
申请号：US15564224
申请日：2016-04-04
Applicant: Cytiva BioProcess R&D AB
Inventor： Martin Hall , Mikael Berg , Ida Eklind , Sandeep Kristiansson
Abstract: The present invention relates to the field of chromatography. More closely, the invention relates to a chromatographic method for purification of Factor VIII and von Willebrand factor from a cryoprecipitate of plasma. The chromatographic method is performed on a matrix comprising an inner porous core and outer porous lid surrounding said core.
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公开(公告)号：US20230091082A1
公开(公告)日：2023-03-23
申请号：US18059929
申请日：2022-11-29
Applicant: Cytiva BioProcess R&D AB
Inventor： Martin Hall , Karolina Busson , Jean-Luc Maloisel , Helena Skoglar
IPC: C07K1/18 , B01J41/20 , B01D15/36 , B01D15/38 , A61K38/36 , A61K38/48 , A61K35/16 , C12N9/64 , B01D15/34 , C07K14/47 , C07K14/755 , C07K14/765 , C07K16/00
Abstract: The present invention relates to the field of chromatography. More closely, the invention relates to a chromatographic method for purification of proteins, such as Factor VIII, von Willebrand factor and Factor IX. The chromatographic method is performed on a matrix comprising an inner porous core and outer porous lid surrounding said core.
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公开(公告)号：US11517879B2
公开(公告)日：2022-12-06
申请号：US17107600
申请日：2020-11-30
Applicant: Cytiva Bioprocess R&D AB
Inventor： Martin Hall , Sture Larsson , Andreas Muranyi , Gustav Rodrigo , Jinyu Zou , Per-Mikael Aberg
IPC: B01J20/24 , B01D15/38 , B01J20/286 , C07K1/22 , B01J20/32 , C07K14/31 , C07K16/00 , C07K17/00 , B01J20/28 , B01J20/285 , B01J20/289 , C07K17/10
Abstract: The present invention relates to a chromatography ligand, which comprises Domain C from Staphylococcus protein A (SpA), or a functional fragment or variant thereof. The chromatography ligand presents an advantageous capability of withstanding harsh cleaning in place (CIF) conditions, and is capable of binding Fab fragments of antibodies. The ligand may be provided with a terminal coupling group, such as arginine or cysteine, to facilitate its coupling to an insoluble carrier such as beads or a membrane. The invention also relates process of using the ligand in isolation of antibodies, and to a purification protocol which may include washing steps and/or regeneration with alkali.
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公开(公告)号：US11807666B2
公开(公告)日：2023-11-07
申请号：US18059929
申请日：2022-11-29
Applicant: Cytiva BioProcess R&D AB
Inventor： Martin Hall , Karolina Busson , Jean-Luc Maloisel , Helena Skoglar
IPC: C07K1/18 , B01J41/20 , B01D15/36 , B01D15/38 , A61K38/36 , A61K38/48 , A61K35/16 , C12N9/64 , B01D15/34 , C07K14/47 , C07K14/755 , C07K14/765 , C07K16/00 , A61K38/00
CPC classification number: C07K1/18 , A61K35/16 , A61K38/36 , A61K38/4846 , B01D15/34 , B01D15/363 , B01D15/3847 , B01J41/20 , C07K14/472 , C07K14/755 , C07K14/765 , C07K16/00 , C12N9/644 , C12N9/6424 , C12Y304/21022 , A61K38/00
Abstract: The present invention relates to the field of chromatography. More closely, the invention relates to a chromatographic method for purification of proteins, such as Factor VIII, von Willebrand factor and Factor IX. The chromatographic method is performed on a matrix comprising an inner porous core and outer porous lid surrounding said core.
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