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    DESALTING SYSTEM FOR CHROMATOGRAPHY
    2.
    发明公开
    DESALTING SYSTEM FOR CHROMATOGRAPHY 审中-公开

    公开(公告)号：US20230194485A1

    公开(公告)日：2023-06-22

    申请号：US17553956

    申请日：2021-12-17

    Applicant: Dionex Corporation

    Inventor： Yongjing Chen ,  Yan Liu

    IPC: G01N30/86 ,  G01N30/72

    CPC classification number: G01N30/8675 ,  G01N30/72 ,  G01N2030/328

    Abstract: An analytical system comprises a chromatography column configured to separate a sample into one or more analytes; an ion removal device configured to remove at least ions of one charge from the mobile phase, the ion removal device fluidly coupled to an output of the chromatography column; an ion selective sensor configured to measure a signal corresponding to an activity of the ions of one charge in the mobile phase, the ion selective sensor fluidly coupled to an output of the ion removal device; an optional diverter valve that can interrupt the flow of the mobile phase; and a microprocessor configured to monitor the signal of the ion selective sensor and to either switch the optional diverter valve to interrupt the flow of the mobile phase or turn off the pump when the signal is greater than a predetermined threshold.

    Large capacity acid or base generator and method of use
    3.
    发明授权
    Large capacity acid or base generator and method of use 有权

    公开(公告)号：US09645124B2

    公开(公告)日：2017-05-09

    申请号：US13738632

    申请日：2013-01-10

    Applicant: Dionex Corporation

    Inventor： Yan Liu ,  Hamish Small ,  Nebojsa Avdalovic

    IPC: G01N30/02 ,  G01N30/26 ,  G01N30/34 ,  G01N30/96 ,  C25B1/16 ,  C25B1/22

    CPC classification number: G01N30/96 ,  C25B1/16 ,  C25B1/22 ,  G01N30/02 ,  G01N30/34 ,  G01N2030/965 ,  Y10T436/25 ,  B01D15/36 ,  B01D15/426

    Abstract: Method and apparatus for generating an acid or base, e.g. for chromatographic analysis of anions. For generating a base the method includes the steps of providing a cation source in a cation source reservoir, flowing an aqueous liquid stream through a base generation chamber separated from the cation source reservoir by a barrier (e.g. a charged membrane) substantially preventing liquid flow while providing a cation transport bridge, applying an electric potential between an anode cation source reservoir and a cathode in the base generation chamber to electrolytically generate hydroxide ions therein and to cause cations in the cation source reservoir to electromigrate and to be transported across the barrier toward the cathode to combine with the transported cations to form cation hydroxide, and removing the cation hydroxide in an aqueous liquid stream as an effluent from the first base generation chamber. Suitable cation sources include a salt solution, a cation hydroxide solution or cation exchange resin.

    Fast startup ion chromatography system and methods
    4.
    发明授权
    Fast startup ion chromatography system and methods 有权

    公开(公告)号：US12130269B2

    公开(公告)日：2024-10-29

    申请号：US17459757

    申请日：2021-08-27

    Applicant: DIONEX CORPORATION

    Inventor： Kannan Srinivasan ,  Mrinal Sengupta ,  Yan Liu ,  Christopher A. Pohl ,  Nebojsa Avdalovic

    IPC: G01N30/96 ,  B01D15/36 ,  G01N30/28

    CPC classification number: G01N30/96 ,  B01D15/362 ,  B01D15/367 ,  G01N2030/285

    Abstract: Systems and methods for inhibiting translocation of ions across ion exchange barriers include an eluent generator having an ion source reservoir with a first electrode, an eluent generation chamber with a second electrode, an ion exchange barrier disposed therebetween, and means for reversing the polarity of a voltage or current applied across the first and second electrodes. A first polarity voltage or current applied across the electrodes generates an electric field that promotes translocation of eluent counter ions from the reservoir across the barrier, where the counter ions combine with eluent ions electrolytically generated in the chamber. By reversing the polarity of the voltage or current across the electrodes, the resulting electric field inhibits translocation of counter ions across the barrier from the reservoir into the chamber. Reverse voltage or current bias reduces counter ion concentration in the resting chamber to prevent exhaustion of ion suppressor capacity during start up.

    PLATINUM ELECTRODE SYSTEM
    5.
    发明公开
    PLATINUM ELECTRODE SYSTEM 审中-公开

    公开(公告)号：US20240201180A1

    公开(公告)日：2024-06-20

    申请号：US18068219

    申请日：2022-12-19

    Applicant: DIONEX CORPORATION

    Inventor： Jun Cheng ,  Yan Liu ,  Arshdeep Kaur

    IPC: G01N33/543 ,  G01N27/30 ,  G01N27/327 ,  G01N27/404

    CPC classification number: G01N33/5438 ,  G01N27/301 ,  G01N27/3273 ,  G01N27/4045

    Abstract: A detection cell for a chromatography system, the detection cell includes a cell body including a counter electrode in the form of the cell body or a wire; a working electrode block including a working electrode; a gasket separating the working electrode block from the cell body, the gasket defining a sample flow pathway extending between an inlet and an outlet of the detection cell and in fluid contact with the cell body, the counter electrode, and the working electrode; and a reference electrode system in fluidic contact with the outlet and including a platinum auxiliary electrode operably connected to a positive pole of a power supply and a platinum reference electrode operably connected to a negative pole of the power supply.

    Sample Tracking Workflow and Method
    8.
    发明申请
    Sample Tracking Workflow and Method 有权

    公开(公告)号：US20250037053A1

    公开(公告)日：2025-01-30

    申请号：US18360586

    申请日：2023-07-27

    Applicant: Dionex Corporation

    Inventor： Yongjing Chen ,  Yan Liu ,  Husam Al-Esawi

    IPC: G06Q10/0633 ,  G06V30/224 ,  G08B21/18

    Abstract: Disclosed herein are scientific instrument support systems, as well as related methods, computing devices, and computer-readable media. For example, in some embodiments, samples are tracked using unique identifiers. An autosampler may detect the samples using unique identifiers and provide alerts when the sample is placed in the wrong location or when an incorrect or incompatible workflow is selected for the sample.

    ELECTROLYTIC ELUENT GENERATORS
    9.
    发明公开
    ELECTROLYTIC ELUENT GENERATORS 审中-公开

    公开(公告)号：US20240269581A1

    公开(公告)日：2024-08-15

    申请号：US18167979

    申请日：2023-02-13

    Applicant: DIONEX CORPORATION

    Inventor： Yongjing Chen ,  Yan Liu

    IPC: B01D15/42 ,  B01D61/44 ,  B01D61/46

    CPC classification number: B01D15/426 ,  B01D61/445 ,  B01D61/46 ,  B01D15/361 ,  B01D2313/13 ,  B01D2313/50 ,  B01D2317/025

    Abstract: An electrolytic eluent generator system includes a flow-through eluent generating zone, a first reservoir comprising configured to hold a first ion source; a second reservoir configured to hold a second ion source; a first ion exchange connector disposed between the first reservoir and the eluent generating zone, wherein the connector substantially prevents liquid flow through the ion exchange connector and transports ions only of the same charge as said first ions; and a second ion exchange connector disposed between the second reservoir and the eluent generation zone, wherein the connector substantially prevents liquid flow through the ion exchange connector and transports ions only of the same charge as said second ions. The second ion exchange connector is of opposite charge to the first ion exchange connector.

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