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公开(公告)号：US06884842B2
公开(公告)日：2005-04-26
申请号：US10055837
申请日：2001-10-26
IPC分类号： C08B37/02 , C08F2/00 , C08G83/00 , G01N33/531 , G01N33/68 , C08G63/48 , C08G63/91 , C08H1/00 , C08G89/00
CPC分类号： C08G83/00 , C08B37/0021 , G01N33/531 , G01N33/68 , G01N2333/976 , G01N2400/22 , G01N2600/00
摘要： Synthetic polymer complements (SPCs) are provided, as well as methods for their synthesis and use. The SPCs may have surfaces that include functional groups that are complementary to surface sites of targets such as nanostructures or macromolecular targets, and may be capable of specifically interacting with such targets. The positions of the functional groups in one embodiment are stabilized by a polymer network. The SPCs are formed by contacting the target with a set of monomers which self-assemble on the target, and then are polymerized into a network to form the synthetic polymer complement. At least a portion of the surface of the resulting SPC thus may include an imprint of the target. The complex of the SPC and the target may be the desired product. Alternatively, the target is released, for example, by controllably expanding and contracting the crosslinked network. The SPC is isolated and used in many applications.
摘要翻译： 提供合成聚合物互补物（SPC），以及其合成和使用的方法。 SPCs可以具有包括与诸如纳米结构或大分子靶标的靶的表面位点互补的官能团的表面，并且可能能够与这些靶特异性相互作用。 在一个实施方案中，官能团的位置由聚合物网络稳定。 SPC通过使靶与在靶上自组装的一组单体接触而形成，然后聚合成网络以形成合成聚合物互补体。 因此，所得SPC的表面的至少一部分可以包括靶的印痕。 SPC和目标物的复合物可能是所需的产品。 或者，目标被释放，例如通过可控地扩展和收缩交联网络。 SPC被隔离并用于许多应用。
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公开(公告)号：US20110208301A1
公开(公告)日：2011-08-25
申请号：US13033474
申请日：2011-02-23
申请人： David Anvar , Andrew Goodwin , David Chazan
发明人： David Anvar , Andrew Goodwin , David Chazan
IPC分类号： A61F2/16 , G02C7/04 , C08K5/5415
CPC分类号： A61F2/1613 , A61L27/14 , A61L27/50 , C07F7/1804 , C07F7/20 , C08G77/34 , C08G77/80 , C08L83/04
摘要： Fluids incorporated into intraocular lenses and their methods of use. In some embodiments the fluids are silicone oils, and in some embodiments they are used in accommodating intraocular lenses.
摘要翻译： 流体入眼内透镜及其使用方法。 在一些实施方案中，流体是硅油，并且在一些实施方案中，它们用于容纳眼内透镜。
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公开(公告)号：US20050228166A1
公开(公告)日：2005-10-13
申请号：US10520249
申请日：2003-07-04
申请人： Cameron Kepert , Andrew Goodwin
发明人： Cameron Kepert , Andrew Goodwin
IPC分类号： C01C3/08 , C01C3/11 , C01C3/12 , C07C211/62 , C07C211/63 , G02B1/00 , G02B1/02 , H01L21/58 , H01L23/14 , H01L41/16 , H01S3/16 , C08G73/00
CPC分类号： C01C3/08 , C01C3/11 , C01C3/12 , C01P2002/76 , C01P2002/77 , C01P2002/82 , C01P2002/84 , C01P2006/32
摘要： A method for controlling the thermal expansion behaviour of a material comprises the step of incorporating into the material a component including one or more diatomic bridges. The or each diatomic bridge extends between two atoms in the component. The method is characterised in that the or each diatomic bridge has at least one vibrational mode that causes the two atoms on either side of the bridge to be moved together to a similar or greater extent than competing vibrational mode(s) that cause the two atoms on either side of the bridge to be moved apart. The bridge may also be polyatomic. New materials and devices comprising a plurality of such diatomic and polyatomic bridges are also defined.
摘要翻译： 用于控制材料的热膨胀行为的方法包括将包括一个或多个双原子桥的组分掺入材料的步骤。 该或每个双原子桥在组件中的两个原子之间延伸。 该方法的特征在于，每个双原子桥具有至少一个振动模式，其使桥的任一侧上的两个原子一起移动到与引起两个原子的竞争振动模式相似或更大的程度 在桥的任一侧被分开。 桥也可能是多原子的。 还定义了包括多个这样的双原子和多原子桥的新材料和器件。
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公开(公告)号：US20050214476A1
公开(公告)日：2005-09-29
申请号：US10509710
申请日：2003-04-08
申请人： Andrew Goodwin , Merlin Patrick
发明人： Andrew Goodwin , Merlin Patrick
CPC分类号： B05D1/62
摘要： A method is disclosed for forming a polymeric coating on a substrate surface, which method comprises the steps of activating (A) at least one monomer selected from (a) at least one polymerizable organic acid monomer comprising at least one acid group and at least one polymerizable group and (b) at least one polymerizable organic acid anhydride monomer comprising at least one acid anhydride group and at least one polymerizable group and (B) at least one polymerizable organic base monomer comprising at least one basic group and at least one polymerizable group by subjecting the monomers to a soft ionization plasma process; and depositing the activated monomers resulting from step (i) onto the substrate surface thereby forming a polymeric coating containing salts resulting from interaction between acidic and basic functional groups on side chains of the polymeric coating. Preferred polymerizable groups are alkenyl groups. Polymeric salt coatings resulting from the above method have excellent barrier properties and coatings in accordance with the present invention will enhance the hydrophilic, biocompatible, anti-fouling and controlled surface pH applications of substrates such as filtration and separations media.
摘要翻译： 公开了一种用于在基材表面上形成聚合物涂层的方法，该方法包括以下步骤：（A）至少一种选自（a）至少一种包含至少一个酸基和至少一个酸基的可聚合有机酸单体的单体 可聚合基团和（b）至少一种包含至少一个酸酐基团和至少一个可聚合基团的可聚合有机酸酐单体和（B）至少一种包含至少一个碱性基团和至少一个可聚合基团的可聚合有机碱单体 通过对单体进行软电离等离子体处理; 以及将由步骤（i）得到的活化单体沉积在基材表面上，从而形成含有由聚合物涂层侧链的酸性和碱性官能团之间的相互作用产生的盐的聚合物涂层。 优选的可聚合基团是烯基。 由上述方法得到的聚合盐涂层具有优异的阻隔性能，并且根据本发明的涂层将增强底物（例如过滤和分离介质）的亲水性，生物相容性，抗结垢和受控表面pH应用。
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公开(公告)号：US09823711B2
公开(公告)日：2017-11-21
申请号：US12895077
申请日：2010-09-30
申请人： Kenneth M. Hopkins , Andrew Goodwin
发明人： Kenneth M. Hopkins , Andrew Goodwin
CPC分类号： G06F1/187
摘要： The invention provides a Storage Bridge Bay system, comprising: plural hard disk drives, each arranged within a corresponding slot; one or more Storage Bridge Bay canisters, wherein there is provided in the or each canister one or more solid state drives. In addition in an embodiment, the invention provides a Storage Bridge Bay canister, the canister comprising: electrical connections in accordance with the Storage Bridge Bay standard; and, one or more solid state drives arranged within the canister and arranged in communication with the electrical connections, thereby enabling control of and transfer of data to or from the solid state drives via the electrical connections.
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公开(公告)号：US08988870B2
公开(公告)日：2015-03-24
申请号：US13169375
申请日：2011-06-27
申请人： Andrew Goodwin , Christopher Girard
发明人： Andrew Goodwin , Christopher Girard
CPC分类号： G06F1/16 , G06F1/187 , G06F3/0626 , G06F3/0658 , G06F3/0689 , G11B33/126 , H05K7/1487
摘要： There is disclosed an electronics module (101) for a data storage device enclosure (100) and data storage device enclosures (100). The module comprises an enclosure connector (104) for connecting to the enclosure, at least one bay constructed and arranged to receive a data storage device (200), and a controller (102) arranged to selectively provide access to storage devices to which it is connected. The module (101) has a communications path (107) between the controller and the enclosure connector (104) by which the controller can communicate with storage devices in the enclosure. The module (101) also has a first communications path to the data storage device (200) when received in the bay by which the controller can communicate with that data storage device. The module (101) also has a second communications path to the data storage device (200) when received in the bay by which that data storage device can be accessed from outside the module.
摘要翻译： 公开了一种用于数据存储设备外壳（100）和数据存储设备外壳（100）的电子模块（101）。 该模块包括用于连接到外壳的外壳连接器（104），构造和布置成接收数据存储设备（200）的至少一个托架以及被配置为选择性地提供对其所在的存储设备的访问的控制器（102） 连接的。 模块（101）具有在控制器和机壳连接器（104）之间的通信路径（107），控制器可以通过该路径与外部存储设备进行通信。 当模块（101）在接收到数据存储设备（200）时，控制器可以通过该第一通信路径与该数据存储设备进行通信。 模块（101）还具有在数据存储设备（200）中接收到的第二通信路径，该数据存储设备（200）在从该模块外部可以访问该数据存储设备的间隔中。
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公开(公告)号：US08900298B2
公开(公告)日：2014-12-02
申请号：US13033474
申请日：2011-02-23
申请人： David Anvar , Andrew Goodwin , David Chazan
发明人： David Anvar , Andrew Goodwin , David Chazan
CPC分类号： A61F2/1613 , A61L27/14 , A61L27/50 , C07F7/1804 , C07F7/20 , C08G77/34 , C08G77/80 , C08L83/04
摘要： Fluids incorporated into intraocular lenses and their methods of use. In some embodiments the fluids are silicone oils, and in some embodiments they are used in accommodating intraocular lenses.
摘要翻译： 流体入眼内透镜及其使用方法。 在一些实施方案中，流体是硅油，并且在一些实施方案中，它们用于容纳眼内透镜。
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公开(公告)号：US20050129769A1
公开(公告)日：2005-06-16
申请号：US10995880
申请日：2004-11-22
申请人： Stephen Barry , Andrew Goodwin , Rachel Decor
发明人： Stephen Barry , Andrew Goodwin , Rachel Decor
IPC分类号： A61K9/16 , A61K9/51 , A61K47/48 , C07C323/59 , C08G63/48 , A61K9/14 , C07C323/25 , C08B33/02 , C08G63/91
CPC分类号： C07C323/59 , A61K9/167 , A61K47/62 , A61K47/6903 , A61K47/6933 , A61K47/6939 , B82Y5/00
摘要： Hydrophilic polymeric nanoarticles comprising a polymeric scaffold and one or more therapeutic agents, such as drug or drug-conjugate molecules, covalently attached to the scaffold. The articles may further optionally comprise recognition elements (REs) that bind to biomolecular structures expressed on certain cells or in certain tissues, to facilitate targeting and/or delivery.
摘要翻译： 亲水性聚合纳米颗粒包含聚合物支架和一种或多种治疗剂，例如药物或药物共轭分子，共价连接到支架上。 制品还可任选地包含结合在某些细胞或某些组织中表达的生物分子结构的识别元件（RE），以促进靶向和/或递送。
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公开(公告)号：US20050226802A1
公开(公告)日：2005-10-13
申请号：US10510538
申请日：2003-04-08
申请人： Andrew Goodwin , Stuart Leadley , Pierre Chevalier
发明人： Andrew Goodwin , Stuart Leadley , Pierre Chevalier
摘要： A method of forming a gel and/or powder of a metallic oxide, metalloid oxide and/or a mixed oxide or resin thereof from one or more respective organometallic liquid precursor(s) and/or organometalloid liquid precursor(s) by oxidatively treating said liquid in a non-thermal equilibrium plasma discharge and/or an ionised gas stream resulting therefrom and collecting the resulting product. The non-thermal equilibrium plasma is preferably atmospheric plasma glow discharge, continuous low pressure glow discharge plasma, low pressure pulse plasma or direct barrier discharge. The metallic oxides this invention particularly relates to are those in columns 3a and 4a of the periodic table namely, aluminium, gallium, indium, tin and lead and the transition metals. The metalloids may be selected from boron, silicon, germanium, arsenic, antimony and tellurium. Preferred metalloid oxide products made according to the process of the present invention are in particular oxides of silicon including silicone resins and the like, boron, antimony and germanium.
摘要翻译： 一种由一种或多种相应的有机金属液体前体和/或有机金属液体前体形成金属氧化物，准金属氧化物和/或其混合氧化物或树脂的凝胶和/或粉末的方法，通过氧化处理所述 非热平衡等离子体放电中的液体和/或由此产生的电离气流并收集所得产物。 非热平衡等离子体优选为大气等离子体辉光放电，连续低压辉光放电等离子体，低压脉冲等离子体或直接屏障放电。 本发明的金属氧化物特别涉及元素周期表的第3a和4a栏，即铝，镓，铟，锡和铅以及过渡金属。 准金属可以选自硼，硅，锗，砷，锑和碲。 根据本发明方法制备的优选的准金属氧化物产物特别是硅的氧化物，包括硅树脂等，硼，锑和锗。
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公开(公告)号：US20050178330A1
公开(公告)日：2005-08-18
申请号：US10509711
申请日：2003-04-08
申请人： Andrew Goodwin , Stuart Leadley , Frank Swallow , Peter Dobbyn
发明人： Andrew Goodwin , Stuart Leadley , Frank Swallow , Peter Dobbyn
CPC分类号： H05H1/2406 , H05H2001/2412
摘要： An atmospheric pressure plasma assembly (1) comprising a first and second pair of vertically arrayed, parallel spaced-apart planar electrodes (36) with at least one dielectric plate (31) between said first pair, adjacent one electrode and at least one dielectric plate (31) between said second pair adjacent one electrode, the spacing between the dielectric plate and the other dielectric plate or electrode of each of the first and second pairs of electrodes forming a first and second plasma regions (25,60) characterised in that the assembly further comprises a means of transporting a substrate (70,71,72) successively through said first and second plasma regions (25,60) and an atomiser (74) adapted to introduce an atomised liquid or solid coating making material into one of said first or second plasma regions.
摘要翻译： 一种大气压等离子体组件（1），包括第一和第二对垂直排列的平行隔开的平面电极（36），所述平面电极具有在所述第一对之间，相邻的一个电极和至少一个电介质板之间的至少一个电介质板（31） （31）在所述第二对相邻的一个电极之间，所述电介质板和所述第一和第二对电极中的每一对电极的另一电介质板或电极之间的间隔形成第一和第二等离子体区域（25,60），其特征在于， 组件还包括将衬底（70,71,72）连续地传送通过所述第一和第二等离子体区域（25,60）和雾化器（74）的装置，所述雾化器适于将雾化的液体或固体涂层制造材料引入所述 第一或第二等离子体区域。
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