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公开(公告)号：US07123358B2
公开(公告)日：2006-10-17
申请号：US10610481
申请日：2003-06-30
CPC分类号： G02B21/365 , C08K9/02 , C08K2201/014 , G01B11/2545 , G01J3/2823 , G01J3/44 , G01J3/447 , G01N21/3563 , G01N21/65 , G02B6/32 , G02B21/00 , G02B21/06 , G06K9/00013 , G06T5/50
摘要： An ion implanted semiconductor surface is illuminated with a flood illumination of monochromatic radiation, and an image of the surface is taken using light which has been Raman scattered. The illumination and imaging system are calibrated by flood illuminating a uniformly Raman scattering surface.
摘要翻译： 用单色辐射的泛光照射照射离子注入的半导体表面，并且使用已经被拉曼散射的光进行表面的图像。 照明和成像系统通过泛光照射均匀的拉曼散射表面来校准。
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2.发明授权Method and apparatus for compact spectrometer for detecting hazardous agents 有权用于检测危险物质的紧凑型光谱仪的方法和装置公开(公告)号：US07738095B2
公开(公告)日：2010-06-15
申请号：US11366532
申请日：2006-03-03
申请人： Charles W. Gardner, Jr. , John S. Maier , Matthew P. Nelson , Robert C. Schweitzer , Patrick J. Treado , G. Steven Vanni , Julianne Wolfe , Joseph E. Demuth , Jason H. Neiss , Chenhui Wang
发明人： Charles W. Gardner, Jr. , John S. Maier , Matthew P. Nelson , Robert C. Schweitzer , Patrick J. Treado , G. Steven Vanni , Julianne Wolfe , Joseph E. Demuth , Jason H. Neiss , Chenhui Wang
CPC分类号： G01J3/44 , G01J3/02 , G01J3/0205 , G01J3/0218 , G01J3/0256 , G01J3/0264 , G01J3/0272 , G01J3/0283 , G01J3/0291 , G01J3/10 , G01J3/26 , G01J3/28 , G01J3/2823 , G01N21/6456 , G01N21/65 , G01N2021/6423 , G01N2201/0221
摘要： The disclosure relates to a portable system for obtaining a spatially accurate wavelength-resolved image of a sample having a first and a second spatial dimension that can be used for the detection of hazardous agents by irradiating a sample with light, forming an image of all or part of the sample using Raman shifted light from the sample, and analyzing the Raman shifted light for patterns characteristic of one or more hazardous agents.
摘要翻译： 本公开涉及一种便携式系统，用于获得具有第一和第二空间尺寸的样本的空间上准确的波长分辨图像，该图像可以用于通过用光照射样品来检测危险剂，形成全部或全部图像 使用拉曼的样品的一部分移动来自样品的光，并且分析拉曼偏移光以获得一种或多种危险剂的特征。
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公开(公告)号：US20120105838A1
公开(公告)日：2012-05-03
申请号：US13374703
申请日：2012-01-09
CPC分类号： G01N21/65 , G01N21/64 , G01N21/6402 , G01N21/8483 , G01N2021/6417
摘要： The invention relates to apparatus and methods for assessing occurrence of a hazardous agent in a sample by performing multipoint spectral analysis of the sample. Methods of employing Raman spectroscopy and other spectrophotometric methods are disclosed. Devices and systems suitable for performing such multipoint methods are also disclosed.
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公开(公告)号：US20090097020A1
公开(公告)日：2009-04-16
申请号：US11000683
申请日：2004-11-30
IPC分类号： G01N21/25
CPC分类号： G01N21/65 , G01N21/64 , G01N21/6402 , G01N21/8483 , G01N2021/6417
摘要： The invention relates to apparatus and methods for assessing occurrence of a hazardous agent in a sample by performing multipoint spectral analysis of the sample. Methods of employing Raman spectroscopy and other spectrophotometric methods are disclosed. Devices and systems suitable for performing such multipoint methods are also disclosed.
摘要翻译： 本发明涉及通过对样品进行多点光谱分析来评估样品中危险剂的发生的装置和方法。 公开了采用拉曼光谱法和其他分光光度法的方法。 还公开了适于执行这种多点方法的设备和系统。
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公开(公告)号：US07538869B2
公开(公告)日：2009-05-26
申请号：US11000683
申请日：2004-11-30
CPC分类号： G01N21/65 , G01N21/64 , G01N21/6402 , G01N21/8483 , G01N2021/6417
摘要： The invention relates to apparatus and methods for assessing occurrence of a hazardous agent in a sample by performing multipoint spectral analysis of the sample. Methods of employing Raman spectroscopy and other spectrophotometric methods are disclosed. Devices and systems suitable for performing such multipoint methods are also disclosed.
摘要翻译： 本发明涉及通过对样品进行多点光谱分析来评估样品中危险剂的发生的装置和方法。 公开了使用拉曼光谱法和其他分光光度法的方法。 还公开了适于执行这种多点方法的设备和系统。
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公开(公告)号：US20110299071A1
公开(公告)日：2011-12-08
申请号：US12422360
申请日：2009-04-13
CPC分类号： G01N21/65 , G01N21/64 , G01N21/6402 , G01N21/8483 , G01N2021/6417
摘要： The invention relates to apparatus and methods for assessing occurrence of a hazardous agent in a sample by performing multipoint spectral analysis of the sample. Methods of employing Raman spectroscopy and other spectrophotometric methods are disclosed. Devices and systems suitable for performing such multipoint methods are also disclosed.
摘要翻译： 本发明涉及通过对样品进行多点光谱分析来评估样品中危险剂的发生的装置和方法。 公开了采用拉曼光谱法和其他分光光度法的方法。 还公开了适于执行这种多点方法的设备和系统。
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7.发明授权Method and apparatus for compact spectrometer for multipoint sampling of an object 有权用于多物体采样的紧凑型光谱仪的方法和装置公开(公告)号：US07548310B2
公开(公告)日：2009-06-16
申请号：US11366660
申请日：2006-03-03
申请人： Charles W. Gardner, Jr. , John S. Maier , Matthew P. Nelson , Robert C. Schweitzer , Patrick J. Treado , G. Steven Vanni , Julianne Wolfe , Joseph E. Demuth , Jason H. Neiss , Chenhui Wang
发明人： Charles W. Gardner, Jr. , John S. Maier , Matthew P. Nelson , Robert C. Schweitzer , Patrick J. Treado , G. Steven Vanni , Julianne Wolfe , Joseph E. Demuth , Jason H. Neiss , Chenhui Wang
IPC分类号： G01J3/44
CPC分类号： G01N21/65 , G01N21/6456 , G01N2021/6421 , G01N2201/0221
摘要： The disclosure relates to methods and apparatus for assessing occurrence of one or more hazardous agents in a sample by performing multipoint spectral analysis of the sample using a portable or hand-held device. Methods of employing Raman spectroscopy and other spectrophotometric methods are disclosed. Devices and systems suitable for performing such multipoint methods are also disclosed.
摘要翻译： 本公开涉及通过使用便携式或手持式装置对样品进行多点光谱分析来评估样品中一种或多种危险剂的发生的方法和装置。 公开了采用拉曼光谱法和其他分光光度法的方法。 还公开了适于执行这种多点方法的设备和系统。
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8.发明授权Method and apparatus for compact spectrometer for fiber array spectral translator 有权用于光纤阵列光谱转换器的紧凑型光谱仪的方法和装置公开(公告)号：US07440096B2
公开(公告)日：2008-10-21
申请号：US11366531
申请日：2006-03-03
申请人： Charles W. Gardner, Jr. , John S. Maier , Matthew P. Nelson , Robert C. Schweitzer , Patrick J. Treado , G. Steven Vanni , Julianne Wolfe , Joseph E. Demuth , Jason H. Neiss , Chenhui Wang
发明人： Charles W. Gardner, Jr. , John S. Maier , Matthew P. Nelson , Robert C. Schweitzer , Patrick J. Treado , G. Steven Vanni , Julianne Wolfe , Joseph E. Demuth , Jason H. Neiss , Chenhui Wang
CPC分类号： G01J3/44 , G01J3/02 , G01J3/0205 , G01J3/0218 , G01J3/0224 , G01J3/0237 , G01J3/0256 , G01J3/0264 , G01J3/0272 , G01J3/0283 , G01J3/0291 , G01J3/10 , G01J3/26 , G01J3/32 , G01J3/36 , G01J3/447 , G01N21/65 , G01N2201/0846
摘要： The disclosure relates to a portable system having a fiber array spectral translator (“FAST”) for obtaining a spatially accurate wavelength-resolved image of a sample having a first and a second spatial dimension that can be used for the detection of hazardous agents by irradiating a sample with light, forming an image of all or part of the sample using Raman shifted light from the sample, and analyzing the Raman shifted light for patterns characteristic of one or more hazardous agents.
摘要翻译： 本公开涉及一种具有光纤阵列光谱转换器（“FAST”）的便携式系统，用于获得具有第一和第二空间尺寸的样品的空间准确的波长分辨图像，所述第一和第二空间尺寸可用于通过照射来检测危险物质 具有光的样品，使用来自样品的拉曼移动光形成全部或部分样品的图像，并且分析拉曼偏移光以获得一种或多种危险剂的特征。
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公开(公告)号：US07330746B2
公开(公告)日：2008-02-12
申请号：US11146458
申请日：2005-06-07
IPC分类号： A61B5/00
CPC分类号： A61B5/14546 , A61B5/14532 , A61B5/1455 , A61B5/415 , A61B5/418
摘要： The invention relates to methods and devices for assessing one or more blood components in an animal. The present invention permits non-invasive assessment of blood components in a body structure containing blood and other tissue types by assessing multiple regions of a tissue surface for an optical characteristic of blood and separately assessing one or more optical (e.g., Raman or NIR) characteristics of the blood component for one or more regions that exhibit the optical characteristic of blood.
摘要翻译： 本发明涉及用于评估动物体内一种或多种血液成分的方法和装置。 本发明通过评估血液的光学特性的组织表面的多个区域并分别评估一种或多种光学（例如，拉曼或NIR）特征，允许对包含血液和其它组织类型的体内结构中的血液成分进行非侵入性评估 的血液成分用于表现出血液光学特性的一个或多个区域。
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公开(公告)号：US07218822B2
公开(公告)日：2007-05-15
申请号：US10956044
申请日：2004-10-04
CPC分类号： A61B1/00165 , A61B1/043 , A61B1/07 , A61B5/0075 , A61B5/0084 , G01J3/02 , G01J3/021 , G01J3/0218 , G01J3/0256 , G01J3/0264 , G01J3/0291 , G01J3/32 , G01J3/44 , G01J2003/1213 , G01N21/33 , G01N21/359 , G01N21/474 , G01N21/645 , G01N21/65 , G01N2021/3155 , G01N2021/4742 , G01N2021/6419 , G01N2021/6421 , G01N2021/6484 , G01N2021/656 , G02B6/06 , G02B6/29398 , G02B23/2423 , G02B23/2469
摘要： The disclosure generally relates to a method and apparatus for a fiberscope. In one embodiment, the disclosure relates to a chemical imaging fiberscope for imaging and collecting optical spectra from a sample having at least one illumination fiber for transmitting light from a first an a second light source to a distal end of a fiberscope; a dichroic mirror disposed at said distal end of the fiberscope such that light from said first light source passes substantially straight through said mirror and light of a predetermined wavelength from said second light source is substantially reflected by said mirror toward said sample to thereby illuminate said sample; and at least one collection fiber for receiving light from said illuminated sample and transmitting the received light to an optical device.
摘要翻译： 本发明一般涉及一种纤维镜的方法和装置。 在一个实施例中，本公开涉及一种用于从具有至少一个照明光纤的样品成像和收集光谱的化学成像光纤镜，用于将光从第一光源传输到第二光源到光纤镜的远端; 分光镜，设置在所述纤维内窥镜的所述远端处，使得来自所述第一光源的光基本上直通所述镜，并且来自所述第二光源的预定波长的光被所述反射镜基本上反射到所述样品，从而照亮所述样品 ; 以及至少一个收集光纤，用于接收来自所述照明样品的光并将接收到的光发射到光学装置。
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