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    Magnetic microvalve using metal ball and method of manufacturing the same
    2.
    发明授权
    Magnetic microvalve using metal ball and method of manufacturing the same 有权
    使用金属球的磁性微型阀及其制造方法

    公开(公告)号：US08585013B2

    公开(公告)日：2013-11-19

    申请号：US12872289

    申请日：2010-08-31

    申请人： Kwang Hyo Chung ,  Yo Han Choi ,  Dae Sik Lee ,  Young Jun Kim ,  Moon Youn Jung ,  Seon Hee Park

    发明人： Kwang Hyo Chung ,  Yo Han Choi ,  Dae Sik Lee ,  Young Jun Kim ,  Moon Youn Jung ,  Seon Hee Park

    IPC分类号： F16K31/08

    CPC分类号： F16K99/0001 ,  F16K99/0015 ,  F16K99/0026 ,  F16K99/0034 ,  F16K99/0046 ,  F16K2099/0078

    摘要： There is provided a magnetic microvalve using a metal ball and a method of manufacturing the same. A magnetic microvalve using a metal ball according to an aspect of the invention may include: an upper substrate having a microchannel serving as a passage through which a fluid moves, a fluid inlet through which the fluid flows into the microchannel, and a fluid outlet through which the fluid, having passed through the microchannel, flows out of the microchannel; a lower substrate having a trench locally provided therein; a PDMS/metal ball combination having a metal ball and PDMS surrounding the metal ball so that the metal ball is located in a central portion thereof, the PDMS/metal ball combination being inserted into the trench provided in the lower substrate; and a magnet located above the microchannel, provided in the upper substrate, and generating magnetic force.

    摘要翻译： 提供了使用金属球的磁性微型阀及其制造方法。 使用根据本发明的一个方面的金属球的磁性微型阀可以包括：具有作为流体移动通道的微通道的上基板，流体流入微通道的流体入口，以及流体出口通过 已经通过微通道的流体流出微通道; 具有局部设置在其中的沟槽的下基板; 具有围绕金属球的金属球和PDMS的PDMS /金属球组合，使得金属球位于其中心部分，PDMS /金属球组合插入设置在下基板中的沟槽中; 以及设置在上基板上的微通道上方的磁体，并产生磁力。

    MICRO-SCALED ANIMAL CELL INCUBATOR AND PRODUCTION METHOD THEREOF
    5.
    发明申请
    MICRO-SCALED ANIMAL CELL INCUBATOR AND PRODUCTION METHOD THEREOF 审中-公开
    微量级动物细胞培养物及其生产方法

    公开(公告)号：US20100279396A1

    公开(公告)日：2010-11-04

    申请号：US12746093

    申请日：2008-06-27

    申请人： Yo Han Choi ,  Kwang Hyo Chung ,  Dae Sik Lee ,  Sang Hee Kim ,  Min Suk Jeong ,  Chi Hoon Jun ,  Moon Youn Jung ,  Seon Hee Park

    发明人： Yo Han Choi ,  Kwang Hyo Chung ,  Dae Sik Lee ,  Sang Hee Kim ,  Min Suk Jeong ,  Chi Hoon Jun ,  Moon Youn Jung ,  Seon Hee Park

    IPC分类号： C12M3/00 ,  H05K3/00

    CPC分类号： C12M23/20 ,  B01L3/5027 ,  B01L7/00 ,  C12M23/16 ,  C12M41/12 ,  Y10T29/49124

    摘要： There is provided a cell culture technology for culturing an animal cell in a separate microstructure. The micro-scaled animal cell incubator includes a lower glass substrate having fine hot wires processed with a metal and formed in an upper surface thereof; a first PDMS film attached onto the lower glass substrate to form two or more liquid and solid storage spaces in a position corresponding to the fine hot wires of the lower glass substrate and gas flow channels coupled respectively to the liquid and solid storage spaces to allow generated gases to flow therethrough; a gas-permeable PDMS thin film attached onto the gas flow channels of the PDMS film to pass the generated gases therethrough; a second PDMS film attached onto the PDMS thin film and having a culture medium storage space for storing a culture medium; and an upper glass substrate attached onto the second PDMS film and having fine hot wires formed in a lower surface thereof, the fine hot wires being covered by the PDMS film. The micro-scaled animal cell incubator may be useful to control a temperature of a culture medium to a suitable temperature level, as well as to self-supply gases required for the animal cell culture in a microstructure.

    摘要翻译： 提供了用于在单独的微结构中培养动物细胞的细胞培养技术。 微型动物细胞培养箱包括具有用金属加工并形成在其上表面的细微热丝的下玻璃基板; 附着在下玻璃基板上的第一PDMS膜，以形成两个或多个液体和固体存储空间，该液体和固体储存空间位于对应于分别与液体和固体储存空间相连的下玻璃基板和气流通道的细热线的位置，以允许产生 气体流过其中; 透气的PDMS薄膜，附着在PDMS薄膜的气流通道上，以使产生的气体通过; 附着在PDMS薄膜上并具有用于储存培养基的培养基储存空间的第二PDMS膜; 以及附着在第二PDMS膜上并具有形成在其下表面上的精细热丝的上玻璃基板，细的热丝被PDMS膜覆盖。 微量级动物细胞培养箱可用于将培养基的温度控制到合适的温度水平，以及自动供应在微结构中动物细胞培养所需的气体。