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    Electrohydrodynamic coating fluid delivery apparatus and method
    1.
    发明授权
    Electrohydrodynamic coating fluid delivery apparatus and method 失效
    电动液体输送装置及方法

    公开(公告)号：US07261915B2

    公开(公告)日：2007-08-28

    申请号：US10409590

    申请日：2003-04-09

    申请人： Dennis R. Boulais ,  Eric B. Stenzel

    发明人： Dennis R. Boulais ,  Eric B. Stenzel

    IPC分类号： B05D1/04

    CPC分类号： B05B5/025 ,  A61L31/10 ,  A61L31/16 ,  B05B5/08 ,  B05B5/10 ,  B05B5/16

    摘要： An apparatus and method for improved control of low viscosity fluid flow during electrohydrodynamic spray deposition of the fluid to coat small targets, such as medical devices like stents. The apparatus includes a target holder which applies a first electrical potential to a target, a coating fluid transporter such as a wick, a siphon tube or a siphon tube with a wick therein along which the coating fluid flows from a reservoir to a dispensing end of the transporter, and an electrode which applied a second electrical potential to the coating fluid sufficient to cause the coating fluid to be attracted from the dispensing end of the transporter toward the target. This provides a target coating apparatus with highly self-regulating coating fluid flow characteristics despite the low viscosity of the coating fluid, while producing highly consistent and uniform target coatings.

    摘要翻译： 一种用于改善流体电动喷雾沉积期间对低粘度流体流动的控制的装置和方法，以涂覆小靶，例如支架等医疗装置。 该装置包括向目标物施加第一电位的靶保持器，涂覆流体输送器，例如芯，虹吸管或虹吸管，其中涂覆液沿着该芯从储存器流动到分配端 所述输送器和向所述涂布液施加足够的第二电位以使所述涂布液从所述运送器的分配端朝向所述目标物吸引的电极。 这提供了具有高自我调节涂层流体流动特性的目标涂布装置，尽管涂布液的粘度低，同时产生高度一致和均匀的靶涂层。

    METHOD AND APPARATUS FOR REDUCING A STENT
    2.
    发明申请
    METHOD AND APPARATUS FOR REDUCING A STENT 有权
    减少一个STENT的方法和装置

    公开(公告)号：US20100143526A1

    公开(公告)日：2010-06-10

    申请号：US12709614

    申请日：2010-02-22

    申请人： Eric B. Stenzel

    发明人： Eric B. Stenzel

    IPC分类号： B29C43/22

    CPC分类号： A61F2/82 ,  A61F2002/9522 ,  Y10T29/49913

    摘要： A medical device crimping system comprises a crimper and a plurality of protective strips. The crimper defines a crimping iris, which has an open state and a closed state. In the open state the cross-sectional area of the crimping iris is greater than in the closed state. The plurality of protective strips extend longitudinally through the crimping iris. Each of the strips is radially offset from one another. The strips protect the stent from direct contact with the crimping blades of the crimper.

    摘要翻译： 医疗装置压接系统包括卷边器和多个保护条。 卷曲器定义了卷曲虹膜，其具有打开状态和闭合状态。 在打开状态下，卷曲虹膜的横截面面积大于关闭状态。 多个保护带纵向延伸通过卷曲虹膜。 每个条带彼此径向偏移。 条带保护支架免受卷边机的压接刀片的直接接触。

    Electrostatic coating of a device
    3.
    发明授权
    Electrostatic coating of a device 有权
    设备的静电涂层

    公开(公告)号：US07524527B2

    公开(公告)日：2009-04-28

    申请号：US10440141

    申请日：2003-05-19

    申请人： Eric B. Stenzel

    发明人： Eric B. Stenzel

    IPC分类号： B05D1/34 ,  B05D1/04 ,  A61L27/00

    CPC分类号： A61L31/16 ,  A61L31/10 ,  A61L2420/02 ,  A61L2420/08 ,  Y10T428/254

    摘要： The present invention concerns bio-compatible medical devices and process for preparation thereof. The process includes electrostatically forming a first layer on a structure. The first layer can include a combination of at least one active substance and at least one polymer and/or binder. A second layer is formed on the structure to cover the first layer. The second layer can be a solvent or a combination of solvents. The evaporation of the second layer causes the first layer to reflow and bind to the structure.

    摘要翻译： 本发明涉及生物相容的医疗装置及其制备方法。 该方法包括在结构上静电形成第一层。 第一层可以包括至少一种活性物质和至少一种聚合物和/或粘合剂的组合。 在结构上形成第二层以覆盖第一层。 第二层可以是溶剂或溶剂的组合。 第二层的蒸发使得第一层回流并结合结构。

    Rapid exchange pre-dilator
    4.
    发明授权
    Rapid exchange pre-dilator 有权
    快速交换预扩张器

    公开(公告)号：US08419680B2

    公开(公告)日：2013-04-16

    申请号：US11166539

    申请日：2005-06-24

    申请人： Eric B. Stenzel

    发明人： Eric B. Stenzel

    IPC分类号： A61M29/00 ,  A61F2/06

    CPC分类号： A61M29/02 ,  A61B2017/22094 ,  A61F2/958 ,  A61M25/09041 ,  A61M2025/0183

    摘要： A predilation device may comprise a shaft portion and a distal tip having helical threadings. The predilation device may further include a rapid exchange element rotatably coupled to the shaft portion. A guidewire may slidably engage the rapid exchange element and may guide the predilation device to a lesion site. The predilation device may be positioned with the distal tip abutting the lesion. The shaft portion may be rotated, thereby rotating the tip and causing the tip to pass through the lesion and predilate the lesion. In some embodiments, the tip may remove lesion material.

    摘要翻译： 预制装置可以包括轴部分和具有螺旋螺纹的远侧末端。 预制装置还可以包括可旋转地联接到轴部分的快速交换元件。 导丝可以滑动地接合快速交换元件并且可将引导装置引导到病变部位。 可以使远端尖端邻接病变来定位预定装置。 轴部可以旋转，从而旋转尖端并使尖端穿过病变并使病变发生褥疮。 在一些实施例中，尖端可以去除病变材料。

    Method of cryogenically coating a device
    5.
    发明授权
    Method of cryogenically coating a device 失效
    低温法涂覆器件的方法

    公开(公告)号：US07326433B2

    公开(公告)日：2008-02-05

    申请号：US10916105

    申请日：2004-08-10

    申请人： Eric B. Stenzel

    发明人： Eric B. Stenzel

    IPC分类号： B05D3/00

    CPC分类号： C23C8/02 ,  A61L31/10 ,  A61L31/14 ,  A61L31/16 ,  A61L2300/416 ,  A61L2300/606 ,  A61L2420/02 ,  B05D3/002 ,  B05D3/048 ,  C23C8/40 ,  C23C8/80

    摘要： The present invention is directed to a method for coating a surface of a medical device with a coating composition. The method involves chilling the surface to be coated to below the freezing point of at least one solvent contained in the composition. This coating composition is applied to the chilled surface, and a portion of the coating composition is allowed to freeze onto the surface. The surface can then be heated (either by the application of heat from an external source, by allowing to heat by ambient air) to above the freezing point of the solvent in the coating composition to allow the solvent to thaw and be removed, thereby forming a smooth, uniform coating on the surface of the medical device.

    摘要翻译： 本发明涉及一种用涂料组合物涂覆医疗器械表面的方法。 该方法包括将待涂覆的表面冷却至组合物中所含的至少一种溶剂的凝固点以下。 将该涂料组合物施加到冷却的表面上，并使一部分涂料组合物冷冻到表面上。 然后可以将表面加热（通过外部来源的加热，通过环境空气加热）到涂料组合物中溶剂的凝固点以上，以使溶剂解冻并除去，从而形成 医疗装置表面上光滑均匀的涂层。

    Method and apparatus for reducing a stent
    8.
    发明授权
    Method and apparatus for reducing a stent 有权
    用于减少支架的方法和装置

    公开(公告)号：US08042373B2

    公开(公告)日：2011-10-25

    申请号：US12709614

    申请日：2010-02-22

    申请人： Eric B. Stenzel

    发明人： Eric B. Stenzel

    IPC分类号： B21D41/00

    CPC分类号： A61F2/82 ,  A61F2002/9522 ,  Y10T29/49913

    摘要： A medical device crimping system comprises a crimper and a plurality of protective strips. The crimper defines a crimping iris, which has an open state and a closed state. In the open state the cross-sectional area of the crimping iris is greater than in the closed state. The plurality of protective strips extend longitudinally through the crimping iris. Each of the strips is radially offset from one another. The strips protect the stent from direct contact with the crimping blades of the crimper.

    摘要翻译： 医疗装置压接系统包括卷边器和多个保护条。 卷曲器定义了卷曲虹膜，其具有打开状态和闭合状态。 在打开状态下，卷曲虹膜的横截面面积大于关闭状态。 多个保护带纵向延伸通过卷曲虹膜。 每个条带彼此径向偏移。 条带保护支架免受卷边机的压接刀片的直接接触。

    Method and apparatus for controlled delivery of active substance
    10.
    发明授权
    Method and apparatus for controlled delivery of active substance 有权
    活性物质的控制递送方法和装置

    公开(公告)号：US07435256B2

    公开(公告)日：2008-10-14

    申请号：US10701455

    申请日：2003-11-06

    申请人： Eric B. Stenzel

    发明人： Eric B. Stenzel

    IPC分类号： A61F2/06

    CPC分类号： A61L31/148 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/61 ,  A61L2300/62

    摘要： The invention relates to a method and device for coating a device with time-release drugs by providing a plurality of micro coated pellets having different release rates on the surface of the medical device structure, e.g., a stent. Organizing the micro pellets with different release rates on the structure can result in the structure having a plurality of release regions with varying release profiles.

    摘要翻译： 本发明涉及一种通过在医疗装置结构例如支架的表面上提供具有不同释放速率的多个微涂层丸剂来涂覆具有时间释放药物的装置的方法和装置。 在结构上以不同的释放速率组织微丸可导致结构具有多个具有变化释放曲线的释放区。