公开(公告)号：US06445939B1

公开(公告)日：2002-09-03

申请号：US09370756

申请日：1999-08-09

申请人： Eric Swanson ,  Christopher L. Petersen ,  Edward McNamara ,  Ronald B. Lamport ,  David L. Kelly

发明人： Eric Swanson ,  Christopher L. Petersen ,  Edward McNamara ,  Ronald B. Lamport ,  David L. Kelly

IPC分类号： A61B500

CPC分类号： A61B5/6852 ,  A61B5/0066 ,  G02B6/2552 ,  G02B6/4203

摘要： Ultra-small optical probes comprising a single-mode optical fiber and a lens which has substantially the same diameter as the optical fiber. The optical fiber and lens are positioned in a probe housing which is in the form of an insertional medical device such as a guidewire. Connector elements are provided to facilitate the attachment of the probe to an optical system and the quick disconnection of the probe from the optical system. The probe is used to obtain optical measurements in situ in the body of an organism and can be used to guide interventional procedures by a surgeon.

摘要翻译： 包括单模光纤和具有与光纤基本相同直径的透镜的超小型光学探针。 光纤和透镜被定位在探针壳体中，探针壳体是诸如导丝的插入医疗装置的形式。 提供连接器元件以便于将探针附接到光学系统以及探针与光学系统的快速断开。 该探针用于在生物体内原位获得光学测量，并可用于指导外科医生的介入手术。

公开(公告)号：US06564087B1

公开(公告)日：2003-05-13

申请号：US09359574

申请日：1999-07-22

申请人： Constantinos Pitris ,  Stephen A. Boppart ,  Xingde Li ,  Mark Brezinski ,  Eric Swanson ,  Edward McNamara ,  James G. Fujimoto

发明人： Constantinos Pitris ,  Stephen A. Boppart ,  Xingde Li ,  Mark Brezinski ,  Eric Swanson ,  Edward McNamara ,  James G. Fujimoto

IPC分类号： A61B500

CPC分类号： A61B5/6852 ,  A61B1/00096 ,  A61B1/00172 ,  A61B1/00183 ,  A61B3/1005 ,  A61B3/102 ,  A61B5/0064 ,  A61B5/0066 ,  A61B5/0084 ,  A61B5/445 ,  A61B5/6848 ,  A61B2562/0242 ,  A61B2562/028 ,  B82Y15/00 ,  G01B9/0205 ,  G01B9/02091 ,  G01B11/00 ,  G01B11/026 ,  G01B11/12 ,  G01B11/2441 ,  G01B2290/65 ,  G01J1/00 ,  G01N21/4795 ,  G02B5/1828 ,  G11B7/0037 ,  G11B7/005 ,  G11B7/08564 ,  G11B7/0908 ,  G11B7/0945 ,  G11B7/126 ,  G11B7/127 ,  G11B7/128 ,  G11B7/1353 ,  G11B7/14 ,  G11B7/24 ,  G11B2007/0013 ,  H01S5/141

摘要： A fiber optic needle probe for measuring or imaging the internal structure of a specimen includes a needle defining a bore, an optical fiber substantially positioned within the bore, and a beam director in optical communication with the optical fiber. At least a portion of the wall of the needle is capable of transmitting light. The beam director directs light from the optical fiber to an internal structure being imaged and receives light from the structure through a transparent portion of the wall. An actuating device causes motion of any, or all of, the needle, optical fiber, and beam director to scan the internal structure of the specimen. The fiber optic needle probe allows imaging inside a solid tissue or organ without intraluminal insertion. When used in conjunction with an OCT imaging system, the fiber optic needle probe enables tomographic imaging of the microstructure of internal organs and tissues which were previously impossible to image in a living subject.

摘要翻译： 用于测量或成像试样的内部结构的光纤针头探针包括限定孔的针，基本上位于孔内的光纤，以及与光纤光学通信的光束指向器。 针的壁的至少一部分能够透光。 光束指示器将光从光纤引导到被成像的内部结构，并且通过壁的透明部分接收来自结构的光。 致动装置导致针，光纤和光束导向器中的任何一个或全部的运动扫描样本的内部结构。 光纤针头探针允许在没有腔内插入的情况下在固体组织或器官内进行成像。 当与OCT成像系统结合使用时，光纤针头探针能够对以前不可能在活体中形成的内部器官和组织的微结构进行层析成像。

公开(公告)号：US20050201662A1

公开(公告)日：2005-09-15

申请号：US11108465

申请日：2005-04-18

申请人： Christopher Petersen ,  Edward McNamara ,  Ronald Lamport ,  Michael Atlas ,  Joseph Schmitt ,  Eric Swanson ,  Paul Magnin

发明人： Christopher Petersen ,  Edward McNamara ,  Ronald Lamport ,  Michael Atlas ,  Joseph Schmitt ,  Eric Swanson ,  Paul Magnin

IPC分类号： G02B23/26 ,  A61B1/00 ,  A61B5/00 ,  G02B23/24 ,  A61B18/18

CPC分类号： G02B23/2407 ,  A61B5/0066 ,  A61B5/0084 ,  A61B5/6852 ,  G01B9/0205 ,  G01B9/02091

摘要： Optical probes having a diameter less than substantially 500 μm for use in scanning light from a long, highly flexible fiber to a sample. In one embodiment the probe includes a viscous damping fluid suitable to prevent non-uniform rotational distortion (NURD).

摘要翻译： 直径小于大约500μm的光学探针用于从长的，高度柔性的光纤到样品的光线扫描。 在一个实施例中，探针包括适于防止不均匀旋转失真（NURD）的粘性阻尼流体。

公开(公告)号：US11802759B2

公开(公告)日：2023-10-31

申请号：US17221835

申请日：2021-04-04

申请人： Eric Swanson

发明人： Eric Swanson

IPC分类号： G01B9/02 ,  G01B9/02091 ,  G01B9/02001 ,  G01B9/02055 ,  G06T11/00 ,  G01B9/02004 ,  G01B9/02015

CPC分类号： G01B9/02091 ,  G01B9/02004 ,  G01B9/02011 ,  G01B9/02015 ,  G01B9/02067 ,  G06T11/005 ,  G06T11/008

摘要： An interferometric measurement system includes ports configured to receive an optical signal from an optical source and an optical signal from a target. A photonic integrated circuit includes a variable delay configured to select between at least two optical paths from the input to an output such that the optical signal from the optical source passes to the output while experiencing an optical delay based on a selected one of the at least two optical paths where a loss of the optical signal from the optical source provided to the input that passes to the output is nominally the same for each of the at least two optical paths. An optical receiver is configured to receive the optical signal from the target and to receive the optical signal from the optical source that experiences the optical delay based on the selected one of the at least two optical paths and generates a corresponding electrical receive signal at an electrical output. A processor is configured to generate an interferometric measurement signal based on the receive signal.

公开(公告)号：US11681093B2

公开(公告)日：2023-06-20

申请号：US16865454

申请日：2020-05-04

申请人： Eric Swanson ,  Anthony Kam

发明人： Eric Swanson ,  Anthony Kam

IPC分类号： A61B1/00 ,  A61B1/07 ,  A61B3/10 ,  A61B5/00 ,  A61B5/02 ,  G02B6/02 ,  G01B9/02091

CPC分类号： G02B6/02042 ,  A61B1/0016 ,  A61B1/00096 ,  A61B1/00167 ,  A61B1/00172 ,  A61B1/00177 ,  A61B1/07 ,  A61B3/10 ,  A61B5/0066 ,  A61B5/0084 ,  A61B5/02007 ,  A61B5/6852 ,  G01B9/02091

摘要： An optical probe imaging system includes an optical probe having a multicore optical fiber. Distal optics image light propagating in the multicore optical fiber so as to generate a light pattern on a sample that is based on a relative position of the cores. A distal motor causes the light pattern to traverse a path across the sample. An optical receiver includes a first receiver receiving light that has traversed the path across the sample from one of the at least two cores and a second receiver receiving light that has traversed the path across the sample from the other of the cores, such that the first receiver and the second receiver detect light in parallel. A processor maps relative position of the cores at the distal facet based on signals generated by the receiver.

公开(公告)号：US11579356B2

公开(公告)日：2023-02-14

申请号：US17577062

申请日：2022-01-17

申请人： Eric Swanson

发明人： Eric Swanson

IPC分类号： G02B6/02 ,  G01N21/17 ,  G02B6/293 ,  A61B5/00 ,  G01B9/02004 ,  G01B9/02 ,  G01B9/02091 ,  G01B9/02055 ,  G01N21/39 ,  G01N21/47 ,  H04B10/61 ,  G01S7/481 ,  G01S17/89 ,  G02F1/29

摘要： An integrated optical system includes a wavelength tunable optical source and a photonic integrated circuit (PIC). The PIC includes a set of spatial waveguide switches having an input optically coupled to the wavelength tunable optical source and a plurality of outputs. The PIC also includes an optical emitter having a plurality of inputs, each being coupled to a respective one of the plurality of outputs of the set of spatial waveguide switches, the optical emitter configured to produce at an output an optical beam having a wavelength dependent emission direction that changes as light is switched by the set of spatial waveguide switches such that the optical beam may be steered in two dimensions.

公开(公告)号：US11243346B2

公开(公告)日：2022-02-08

申请号：US17019228

申请日：2020-09-12

申请人： Eric Swanson

发明人： Eric Swanson

IPC分类号： G01N21/17 ,  G02B6/02 ,  G02B6/293 ,  A61B5/00 ,  G01B9/02 ,  G01N21/39 ,  G01N21/47 ,  H04B10/61 ,  G01S7/481 ,  G01S17/89 ,  G02F1/29

摘要： An optical-fiber measurement system includes an optical transceiver comprising an optical transmitter and an optical receiver. A multi-core optical fiber has a proximal end with a first optical core coupled to the transceiver and a second optical core coupled to the transceiver, and a distal end with the first optical core coupled to a sample path that is configured to convey light collected from a sample positioned external to the multi-core optical fiber and the second optical core coupled to a reference path such that the sample path and the reference path experience mostly a same disturbance along the multi-core optical fiber. The optical receiver is configured to interferometrically detect light from the sample path and light from the reference path.

公开(公告)号：US20210278196A1

公开(公告)日：2021-09-09

申请号：US17327629

申请日：2021-05-21

申请人： Eric Swanson

发明人： Eric Swanson ,  Christopher Doerr

IPC分类号： G01B9/02 ,  H01S3/10

摘要： A wavelength tunable laser device includes a gain element positioned in an optical cavity that provides optical gain to an optical signal. A frequency shifter that generates a frequency shift as a function of time is positioned in the optical cavity. The optical cavity is configured so that a magnitude of the frequency shift as a function of time generated by the frequency shifter is substantially equal to a frequency separation of a cavity mode of the cavity such that an output of the cavity generates laser light having a wavelength that tunes as a function of time.

公开(公告)号：US10741910B2

公开(公告)日：2020-08-11

申请号：US16018537

申请日：2018-06-26

申请人： Eric Swanson

发明人： Eric Swanson

IPC分类号： G02F1/01 ,  H01Q3/26 ,  G02B27/00 ,  H01S3/067 ,  A61B1/00 ,  G01S17/89 ,  G01S7/481 ,  A61B5/00

摘要： An optical system for producing an optical probe beam includes an optical source that generates a free-space optical beam. An optical element is positioned in a path of the free-space optical beam to project the free-space optical beam to generate a projected free-space optical beam. A photonic integrated phased-array component positioned in a path of the projected free-space optical beam to reflect the projected free space optical beam, thereby generating the optical probe beam. The photonic integrated phased-array component comprises a plurality of antenna elements and a substrate positioned proximate to the plurality of antenna elements, wherein the substrate includes a plurality of fan-out electrical connections from at least some of the plurality of antenna elements such that a size of a region comprising the fan-out electrical connections is larger than a size of a region comprising the plurality of antenna elements.

公开(公告)号：US10132610B2

公开(公告)日：2018-11-20

申请号：US15244503

申请日：2016-08-23

申请人： Eric Swanson

发明人： Eric Swanson ,  Christopher Doerr

IPC分类号： G01B9/02

摘要： Disclosed herein are optical integration technologies, designs, systems and methods directed toward Optical Coherence Tomography (OCT) and other interferometric optical sensor, ranging, and imaging systems wherein such systems, methods and structures employ tunable optical sources, coherent detection and other structures on a single or multichip monolithic integration. In contrast to contemporary, prior-art OCT systems and structures that employ simple, miniature optical bench technology using small optical components positioned on a substrate, systems and methods according to the present disclosure employ one or more photonic integrated circuits (PICs), use swept-source techniques, and employ a widely tunable optical source(s).