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    USE OF BIOMARKERS AND THERAPEUTIC AGENTS WITH SURGICAL DEVICES
    4.
    发明申请
    USE OF BIOMARKERS AND THERAPEUTIC AGENTS WITH SURGICAL DEVICES 有权
    使用生物标志物和治疗药物与外科手术

    公开(公告)号：US20140051950A1

    公开(公告)日：2014-02-20

    申请号：US14062276

    申请日：2013-10-24

    申请人： Ethicon Endo-Surgery, Inc.

    发明人： Jeffrey W. Clymer ,  Prasanna Malaviya ,  Donna L. Korvick ,  Kevin L. Houser ,  Cory G. Kimball ,  Frederick E. Shelton, IV ,  Chester O. Baxter, III ,  Taylor W. Aronhalt

    IPC分类号： A61B5/00 ,  A61B18/14 ,  A61B10/06 ,  A61B5/145

    CPC分类号： A61B5/4839 ,  A61B5/14546 ,  A61B5/486 ,  A61B5/7282 ,  A61B5/742 ,  A61B10/0283 ,  A61B10/06 ,  A61B18/1445 ,  A61B2046/236 ,  A61B2218/008 ,  A61M2037/0007

    摘要： Biomarkers are collected and used to determine biological propensities of a patient, to determine the efficacy of medical devices, to select and administer therapeutic agents, to select medical devices, to make adjustments to medical devices, and/or to adjust surgical techniques. An apparatus includes a port to draw a biological fluid (e.g., a mist) from a surgical site. The apparatus includes a sensor having a cantilevered beam. The beam includes substances selected to attract certain biomarkers as the fluid is communicated across the beam. The same apparatus or another apparatus is used to administer a therapeutic agent based at least in part on collected biomarker data. The therapeutic agent delivery apparatus may include a device that is also used to create a wound at a surgical site. For instance, a harmonic surgical instrument may be used to both collect biomarkers and administer a therapeutic agent (e.g., gene therapy using sonoporation).

    摘要翻译： 生物标志物被收集并用于确定患者的生物倾向性，以确定医疗装置的功效，选择和施用治疗剂，选择医疗装置，调整医疗装置和/或调整手术技术。 一种装置包括从外科手术部位抽取生物流体（例如，雾）的端口。 该装置包括具有悬臂梁的传感器。 梁包括当流体在横梁上连通时选择用于吸引某些生物标志物的物质。 使用相同的装置或另一装置至少部分地基于收集的生物标志物数据来施用治疗剂。 治疗剂递送装置可以包括也用于在手术部位创建伤口的装置。 例如，可以使用谐波手术器械来收集生物标志物并施用治疗剂（例如，使用声波光刻的基因治疗）。

    Surgical instrument
    5.
    发明授权
    Surgical instrument 有权

    公开(公告)号：US10524854B2

    公开(公告)日：2020-01-07

    申请号：US14947449

    申请日：2015-11-20

    申请人： Ethicon Endo-Surgery, Inc.

    发明人： Scott A. Woodruff ,  Patrick A. Weizman ,  Gwendolyn P. Payne ,  Donna L. Korvick ,  David K. Norvell ,  Aron O. Zingman

    IPC分类号： A61B18/14 ,  A61B18/00 ,  A61B17/32

    摘要： A surgical instrument can comprise a first jaw and second jaw, wherein the first jaw is movable relative to the second jaw to capture tissue having a tissue thickness. A tissue cutting force monitor is configured to determine the tissue thickness of the captured tissue and communicate the tissue thickness to a controller, wherein the controller is configured to adjust the speed of a tissue-cutting element during a cutting portion of a firing stroke based on the tissue thickness communicated from the tissue cutting force monitor. The controller is configured to reduce the speed of the tissue-cutting element when the tissue cutting force monitor communicates a thicker tissue thickness to the controller. The controller is configured to increase the speed of the tissue-cutting element when the tissue cutting force monitor communicates a thinner tissue thickness to the controller.

    Distal sealing end effector with spacers
    9.
    发明授权
    Distal sealing end effector with spacers 有权

    公开(公告)号：US10524852B1

    公开(公告)日：2020-01-07

    申请号：US14229033

    申请日：2014-03-28

    申请人： Ethicon Endo-Surgery, Inc.

    发明人： David J. Cagle ,  Donna L. Korvick ,  Eric N. Johnson

    IPC分类号： A61B18/14

    摘要： A surgical end effector includes a cutting member, a first jaw, and a second jaw. The first jaw includes a first uninterrupted electrically conductive region. The second jaw includes an elongate slot extending longitudinally along a length of the second jaw member, the elongate slot defining a longitudinal axis aligned with the elongate slot. The second jaw also includes a second electrode surface extending between a proximal end and a distal end, the second electrode surface including a proximal interrupted electrically conductive region, a plurality of non-conductive stop members disposed on the proximal interrupted electrically conductive region, and a distal uninterrupted electrically conductive region distal to the proximal interrupted electrically conductive region.