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公开(公告)号：US20120214209A1
公开(公告)日：2012-08-23
申请号：US13458548
申请日：2012-04-27
IPC分类号： C12P19/20 , C12P7/20 , C12P7/56 , C12P7/04 , C12P7/58 , C12P17/04 , C12P7/46 , C12P7/14 , C12P7/18 , C12P7/60
CPC分类号： C12P7/56 , C12P7/06 , C12P7/10 , C12P7/18 , C12P7/20 , C12P7/42 , C12P7/44 , C12P7/46 , C12P7/58 , C12P7/60 , C12P19/02 , C12P2201/00 , Y02E50/16 , Y02E50/17
摘要： The present invention provides means for the production of desired end-products of in vitro and/or in vivo bioconversion of biomass-based feed stock substrates, including but not limited to such materials as starch and cellulose. In particularly preferred embodiments, the methods of the present invention do not require gelatinization and/or liquefaction of the substrate.
摘要翻译： 本发明提供了生产基于生物质的原料基质的体外和/或体内生物转化所需的终产物的方法，包括但不限于淀粉和纤维素等材料。 在特别优选的实施方案中，本发明的方法不需要基质的凝胶化和/或液化。
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公开(公告)号：US20090181433A1
公开(公告)日：2009-07-16
申请号：US12244702
申请日：2008-10-02
IPC分类号： C12P19/02 , C12P1/00 , C12P7/18 , C12P7/58 , C12P7/20 , C12P7/46 , C12P7/56 , C12P7/02 , C12P17/04
CPC分类号： C12P7/56 , C12P7/06 , C12P7/10 , C12P7/18 , C12P7/20 , C12P7/42 , C12P7/44 , C12P7/46 , C12P7/58 , C12P7/60 , C12P19/02 , C12P2201/00 , Y02E50/16 , Y02E50/17
摘要： The present invention provides means for the production of desired end-products of in vitro and/or in vivo bioconversion of biomass-based feed stock substrates, including but not limited to such materials as starch and cellulose. In particularly preferred embodiments, the methods of the present invention do not require gelatinization and/or liquefaction of the substrate.
摘要翻译： 本发明提供了生产基于生物质的原料基质的体外和/或体内生物转化所需的终产物的方法，包括但不限于淀粉和纤维素等材料。 在特别优选的实施方案中，本发明的方法不需要基质的凝胶化和/或液化。
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公开(公告)号：US08597927B2
公开(公告)日：2013-12-03
申请号：US12810004
申请日：2008-12-16
IPC分类号： C12N9/14 , C12N9/16 , C12N9/18 , C12N9/26 , C12N9/44 , C12N9/48 , C12N9/54 , C12N9/58 , C11D7/42
CPC分类号： A01N63/02 , C11D3/386 , C11D3/38636
摘要： The invention provides methods, compositions, and kits for removal of biofilms from surfaces. The methods described herein comprise simultaneous or sequential application of a perhydrolase enzyme and a mixture of other enzymes, such as proteases, glucanases, esterases, mannanases, phospholipases, cellulases, and/or amylases, to a biofilm on a surface, to effect removal of the biofilm.
摘要翻译： 本发明提供从表面去除生物膜的方法，组合物和试剂盒。 本文描述的方法包括同时或顺序地将表面上的生物膜同时或顺序施用过水解酶和其它酶（例如蛋白酶，葡聚糖酶，酯酶，甘露聚糖酶，磷脂酶，纤维素酶和/或淀粉酶）的混合物，以去除 生物膜。
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公开(公告)号：US08551748B2
公开(公告)日：2013-10-08
申请号：US12684390
申请日：2010-01-08
申请人： Manoj Kumar , Mahendra Pratap Singh , Maya Chakradhar , Dheer Singh , Veena Bansal , Vijay Kumar Chhatwal , Ravinder Kumar Malhotra , Anand Kumar
发明人： Manoj Kumar , Mahendra Pratap Singh , Maya Chakradhar , Dheer Singh , Veena Bansal , Vijay Kumar Chhatwal , Ravinder Kumar Malhotra , Anand Kumar
IPC分类号： C12P5/00
摘要： Disclosed herein a process for upgrading the liquid hydrocarbon fuels by reducing aromatic content, sulfur content and nitrogen content wherein the process comprising isolating polycyclic aromatic hydrocarbon (PAH) transforming microbes and preparing biocatalyst by mutagenesis, contacting the biocatalyst with the liquid hydrocarbon fuel in an aqueous medium for transforming the aromatic, sulfur, and nitrogen containing compounds to polar substances, subjecting the mixture of biocatalyst and the liquid hydrocarbon fuel to a process of bioconversion, removing the polar substances by liquid-liquid extraction with a polar solvent to obtain dearomatized, desulphurised and denitrogenated liquid hydrocarbon fuel and recovering the upgraded liquid hydrocarbon fuel.
摘要翻译： 本文公开了通过降低芳烃含量，硫含量和氮含量来提高液体烃燃料的方法，其中所述方法包括通过诱变分离多环芳烃（PAH）转化微生物并制备生物催化剂，使生物催化剂与液体烃燃料在水溶液 用于将芳族，硫和氮的化合物转化为极性物质的介质，使生物催化剂和液体烃燃料的混合物经历生物转化过程，通过用极性溶剂液 - 液萃取除去极性物质，得到脱芳香，脱硫 和脱氮液态烃燃料，并回收升级液化烃燃料。
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5.发明授权公开(公告)号：US08048859B2
公开(公告)日：2011-11-01
申请号：US11860911
申请日：2007-09-25
申请人： Manoj Kumar , William A. Cuevas
发明人： Manoj Kumar , William A. Cuevas
CPC分类号： A61K8/0212 , A61K8/0229 , A61K8/64 , A61K38/1709 , A61K2800/28 , A61Q1/02 , A61Q1/04 , A61Q1/06 , A61Q1/10 , A61Q1/12 , A61Q3/00 , A61Q3/02 , A61Q5/006 , A61Q5/02 , A61Q5/12 , A61Q17/04 , A61Q19/00 , A61Q19/001 , A61Q19/002 , A61Q19/10
摘要： A personal care composition is provided and includes an effective amount of a repeat sequence protein polymer. The personal care composition may be a hair care composition, a skin care composition, a nail care composition, a cosmetic composition, or an over-the-counter pharmaceutical composition.
摘要翻译： 提供个人护理组合物并且包括有效量的重复序列蛋白质聚合物。 个人护理组合物可以是护发组合物，护肤组合物，指甲护理组合物，化妆品组合物或非处方药物组合物。
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6.发明授权Metabolically engineered bacterial strains having non-functional endogenous gluconate transporters 有权具有非功能性内源葡萄糖酸盐转运蛋白的代谢改造的细菌菌株公开(公告)号：US08034583B2
公开(公告)日：2011-10-11
申请号：US12141522
申请日：2008-06-18
IPC分类号： C12P21/06
摘要： The present invention relates to engineering metabolic pathways in bacterial host cells which results in enhanced carbon flow for the production of ascorbic acid (ASA) intermediates. In particular, the invention relates to increasing the production of ASA intermediates in bacterial cells by enhancing the availability of gluconate resulting from the inactivation of endogenous gluconate transporter genes.
摘要翻译： 本发明涉及在细菌宿主细胞中工程代谢途径，其导致用于生产抗坏血酸（ASA）中间体的增强的碳流。 特别地，本发明涉及通过增加由内源性葡萄糖酸转运蛋白基因失活产生的葡萄糖酸盐的可利用性来增加细菌细胞中ASA中间体的产生。
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公开(公告)号：US07919295B2
公开(公告)日：2011-04-05
申请号：US11875788
申请日：2007-10-19
申请人： Manoj Kumar , Susan M. Madrid , Hugh C. McDonald , Ayrookaran J. Poulose , Thomas Rand , Huaming Wang
发明人： Manoj Kumar , Susan M. Madrid , Hugh C. McDonald , Ayrookaran J. Poulose , Thomas Rand , Huaming Wang
CPC分类号： C12N9/0006 , C07K2319/02 , C11D3/38654 , C12Y101/03
摘要： The present invention provides compositions and methods for producing a polyol oxidase in microorganisms, and the use of polyol oxidases in cleaning compositions. The invention includes cleaning compositions that contain combinations of two or more POx oxidases, and cleaning compositions that contain combinations of two or more POx oxidases and a perhydrolase. In particular, the invention provides methods for expressing polyol oxidases in bacterial hosts for use in detergent applications for cleaning, bleaching and disinfecting.
摘要翻译： 本发明提供了用于在微生物中生产多元醇氧化酶的组合物和方法，以及在清洁组合物中使用多元醇氧化酶。 本发明包括含有两种或更多种POx氧化酶的组合的清洁组合物和含有两种或更多种POx氧化酶和过水解酶的组合的清洁组合物。 特别地，本发明提供了用于在洗涤剂应用中用于清洁，漂白和消毒的细菌宿主中表达多元氧化酶的方法。
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8.发明申请Repeat Sequence Protein Polymer Nanoparticles Optionally Containing Active Agents and Their Preparation 审中-公开重复序列蛋白质聚合物纳米粒子，可选含有活性剂及其制备方法公开(公告)号：US20090246283A1
公开(公告)日：2009-10-01
申请号：US12223575
申请日：2007-02-15
申请人： Manoj Kumar
发明人： Manoj Kumar
CPC分类号： A61K9/5169 , A61K9/1694 , A61K9/5192 , A61K38/28 , A61K47/42
摘要： A nanocomposite of a repeat sequence protein polymer, such as a copolymer of silk and elastin, is produced by Supercritical Antisolvent Precipitation with Enhanced Mass Transfer (SAS-EM). The nanocomposite may include an active agent, such as a protein or hormone, that is releasably bound to the repeat sequence protein polymer.
摘要翻译： 重复序列蛋白质聚合物的纳米复合物，如丝和弹性蛋白的共聚物，通过超临界抗溶剂沉淀与增强传质（SAS-EM）产生。 纳米复合材料可以包括可释放地结合重复序列蛋白质聚合物的活性剂，例如蛋白质或激素。
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公开(公告)号：US20090048827A1
公开(公告)日：2009-02-19
申请号：US11840754
申请日：2007-08-17
申请人： Manoj Kumar
发明人： Manoj Kumar
IPC分类号： G10L19/14
CPC分类号： G10L19/005
摘要： The disclosed systems and methods relate to estimating an audio frame. Aspects of the present invention may improve audio quality at the client side when a section of voice data is corrupted or delayed during transmission. The present invention may be suitable for decoding in, for example, circuit switched and packet switched digital voice applications.
摘要翻译： 所公开的系统和方法涉及估计音频帧。 当在传输期间语音数据的一部分被破坏或延迟时，本发明的方面可以改善客户端的音频质量。 本发明可以适用于例如电路交换和分组交换数字语音应用中的解码。
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10.发明申请公开(公告)号：US20080226706A1
公开(公告)日：2008-09-18
申请号：US12062305
申请日：2008-04-03
申请人： Manoj Kumar
发明人： Manoj Kumar
CPC分类号： A61K8/64 , A61K8/0212 , A61K8/0229 , A61K38/1709 , A61K2800/28 , A61Q1/02 , A61Q1/04 , A61Q1/06 , A61Q1/10 , A61Q1/12 , A61Q3/00 , A61Q3/02 , A61Q5/006 , A61Q5/02 , A61Q5/12 , A61Q17/04 , A61Q19/00 , A61Q19/001 , A61Q19/002 , A61Q19/10
摘要： The present invention provides personal care compositions, and more particularly, personal care compositions comprising a bioactively effective amount of a repeat sequence protein polymer. In some particularly preferred embodiments, the present invention provides personal care compositions comprising an effective amount of at least one fragment of a repeat sequence protein polymer having bioactivity.
摘要翻译： 本发明提供了个人护理组合物，更具体地，包括生物活性有效量的重复序列蛋白质聚合物的个人护理组合物。 在一些特别优选的实施方案中，本发明提供了包含有效量的具有生物活性的重复序列蛋白质聚合物的至少一个片段的个人护理组合物。
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