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    Method for collecting information on the primary structure of proteins, hydrophobic microparticulate carrier used in same, and system for automatically obtaining information on the primary structure of proteins
    1.
    发明申请
    Method for collecting information on the primary structure of proteins, hydrophobic microparticulate carrier used in same, and system for automatically obtaining information on the primary structure of proteins 审中-公开
    收集蛋白质主要结构信息的方法，使用的疏水性微粒载体和自动获得蛋白质一级结构信息的系统

    公开(公告)号：US20060084131A1

    公开(公告)日：2006-04-20

    申请号：US11237682

    申请日：2005-09-29

    申请人： Hiroshi Nakayama ,  Hiromi Miura ,  Masaya Iwaki

    发明人： Hiroshi Nakayama ,  Hiromi Miura ,  Masaya Iwaki

    IPC分类号： G06F19/00 ,  C12Q1/37

    CPC分类号： G01N33/6842 ,  C07K1/36 ,  G01N33/6818

    摘要： A method for obtaining information on the primary structure of peptides comprising fragmenting the proteins, which enables automation of obtaining information on the primary structure of a peptide sample; a device for use in the method; and an automatic analysis system on the primary structure of the peptides. The method for obtaining information on the primary structure of peptides comprising the steps of: denaturing, reducing, and alkylating a protein; immobilizing the reduced alkylated protein obtained on a hydrophobic microparticulate carrier; chemically or enzymatically fragmenting the immobilized protein obtained; and obtaining information on the primary structure of the peptides fragmented. The automatic analysis system on the primary structure of the peptides comprising an automatic fragmentation element for automatically fragmenting a reduced and alkylated protein, an automatic mass spectrometry element for automatically analyzing the fragmented peptides by mass spectrometry, and a data analysis element for analyzing the data obtained by the automatic mass spectrometry element. The automatic fragmentation of the reduced and alkylated protein is conducted using a hydrophobic microparticulate carrier.

    摘要翻译： 一种用于获得关于肽的一级结构的信息的方法，包括使所述蛋白质分裂，其能够自动获得关于肽样品的一级结构的信息; 用于该方法的装置; 以及肽的一级结构的自动分析系统。 获得关于肽的一级结构的信息的方法，包括以下步骤：使蛋白质变性，还原和烷基化; 固定在疏水性微粒载体上得到的还原烷基化蛋白质; 化学或酶促分离得到的固定化蛋白质; 并获得关于片段化的肽的一级结构的信息。 包括用于自动分解还原和烷基化蛋白质的自动碎裂元件的肽的一级结构的自动分析系统，用于通过质谱自动分析片段化肽的自动质谱元件和用于分析获得的数据的数据分析元件 通过自动质谱元件。 还原和烷基化蛋白质的自动碎裂使用疏水性微粒载体进行。

    Material for aneurysm curing
    2.
    发明授权
    Material for aneurysm curing 失效
    动脉瘤固化材料

    公开(公告)号：US08268300B2

    公开(公告)日：2012-09-18

    申请号：US13024718

    申请日：2011-02-10

    申请人： Hiroshi Ujiie ,  Yoshiaki Suzuki ,  Masaya Iwaki ,  Takanori Uchida

    发明人： Hiroshi Ujiie ,  Yoshiaki Suzuki ,  Masaya Iwaki ,  Takanori Uchida

    IPC分类号： A61K31/74

    CPC分类号： A61L31/04 ,  A61K31/00 ,  A61L2400/18 ,  A61L2430/36

    摘要： It is an object of the present invention to provide a polymer material, the histocompatibility of which has been improved by irradiation of ion beam, which prevents an aneurysm having a risk of rupture from actually rupturing. The present invention provides a material for treating aneurysms, which is composed of a polymer material containing carbon as a constitutional element, and which is produced by modifying at least a portion of the surface thereof by ion bombardment.

    摘要翻译： 本发明的一个目的是提供一种通过离子束的照射改善了组织相容性的聚合物材料，其防止了具有破裂风险的动脉瘤的实际破裂。 本发明提供一种治疗动脉瘤的材料，其由含有碳作为构成元素的高分子材料构成，其通过离子轰击改性其表面的至少一部分而制成。

    Production of aluminum material having an aluminum nitride layer
    4.
    发明授权
    Production of aluminum material having an aluminum nitride layer 失效
    生产具有氮化铝层的铝材料

    公开(公告)号：US4698233A

    公开(公告)日：1987-10-06

    申请号：US872278

    申请日：1986-06-10

    申请人： Shigeo Ohira ,  Masaya Iwaki

    发明人： Shigeo Ohira ,  Masaya Iwaki

    IPC分类号： C23C14/06 ,  C23C14/22 ,  C23C14/48 ,  B05D3/06

    CPC分类号： C23C14/48

    摘要： Process for producing an aluminum material having an aluminum nitride surface layer which comprises implanting the surface of an aluminum substrate with nitrogen ions while maintaining a nitrogen atmosphere under reduced pressure in the vicinity of the surface of the aluminum substrate. The aluminum nitride modified layer contains substantially no impurities such as oxygen. It is a feature of this invention to perform ion implantation in a properly controlled nitrogen atmosphere at a proper degree of vacuum in the range of about 10.sup.-7 to 10.sup.-5 Torr.

    摘要翻译： 一种具有氮化铝表面层的铝材的制造方法，其包括在铝基板的表面附近保持氮气气氛的同时，保持氮气气氛下的氮离子的铝基板的表面。 氮化铝改性层基本上不含氧等杂质。 本发明的一个特征是在适当控制的氮气气氛中以适当的真空度在约10-7至10-5乇的范围内进行离子注入。

    Electron microscope and method for controlling focus position thereof
    5.
    发明授权
    Electron microscope and method for controlling focus position thereof 失效
    电子显微镜及其对焦位置的控制方法

    公开(公告)号：US06984823B2

    公开(公告)日：2006-01-10

    申请号：US10480535

    申请日：2002-06-10

    申请人： Masaya Iwaki ,  Norio Baba

    发明人： Masaya Iwaki ,  Norio Baba

    IPC分类号： H01J37/21 ,  H01J37/153

    CPC分类号： H01J37/22 ,  H01J2237/216

    摘要： There are provided an electron microscope capable of carrying out focusing and astigmatism correction without depending on characteristics of a sample, and a method for controlling its focus position.The electron microscope according to the present invention comprises: an electron optical system (2); a focus control part (3); an image detecting part (4); a first operating part (11) for mutually dividing first and second transformed images (9) and (10), which are obtained by carrying out the fast Fourier transform of first and second images (7) and (8) detected at two focus positions of a first focus position (f1) and a second focus position (f2) shifted from the first focus position by a known focus shifted quantity Δf, to obtain a measured divided quantity Rexp; divided quantity data (12) previously prepared and stored as a function of focus positions and spatial frequencies as a set of theoretical divided quantities, the theoretical divided quantities being obtained by substituting the two focus positions shifted by the focus shifted quantity Δf for an image transfer function (r,f) to obtain first and second transfer function values K(r;f) and (r;f+Δf) to mutually divide the first and second transfer function values K(r;f1) and (r;f+Δf) on a spatial frequency plane; and a second operating part (13) for making a reference to the divided quantity data (12) to derive a theoretical divided quantity K(r;f0) correlating to the measured divided quantity Rexp, and for deriving a focus position f0 corresponding to the derived theoretical divided quantity K(r;f0)/K(r;f0+Δf) as a first focus position f1.

    摘要翻译： 提供了能够进行聚焦和散光校正的电子显微镜，而不依赖于样品的特性，以及用于控制其焦点位置的方法。 根据本发明的电子显微镜包括：电子光学系统（2）; 聚焦控制部（3）; 图像检测部分（4）; 第一操作部分（11），用于通过执行在两个焦点位置处检测到的第一和第二图像（7）和（8）的快速傅立叶变换来获得第一和第二变换图像（9）和（10） 第一对焦位置（f 1）和第二聚焦位置（f 2）从第一聚焦位置移位已知聚焦移动量Deltaf，以获得测量的分割数Rexp; 预先准备并存储作为焦点位置和空间频率的函数的分割数量数据（12）作为一组理论分割量，理论分割量通过将通过焦点移动量Deltaf移位的两个焦点位置替换为图像传送而获得 函数（r，f）以获得第一和第二传递函数值K（r; f）和（r; f + Deltaf），以将第一和第二传递函数值K（r; f 1）和（r; f + Deltaf）在空间频率平面上; 以及用于参考分割数量数据（12）的第二操作部分（13），以导出与测量的分割数量Rexp相关的理论分割量K（r; f 0），并且用于导出对应的对焦位置f 0 作为第一焦点位置f 1的导出的理论分割量K（r; f 0）/ K（r; f 0 + Deltaf）。

    ULTRASONIC MOTOR AND METHOD FOR MANUFACTURING ULTRASONIC MOTOR
    7.
    发明申请
    ULTRASONIC MOTOR AND METHOD FOR MANUFACTURING ULTRASONIC MOTOR 审中-公开
    超声波电机及制造超声波电机的方法

    公开(公告)号：US20090212660A1

    公开(公告)日：2009-08-27

    申请号：US11912137

    申请日：2006-04-20

    申请人： Masaya Iwaki ,  Tomoko Iwaki ,  Koji Akashi ,  Norimichi Anazawa ,  Ken-ichi Kobayashi

    发明人： Masaya Iwaki ,  Tomoko Iwaki ,  Koji Akashi ,  Norimichi Anazawa ,  Ken-ichi Kobayashi

    IPC分类号： H02N2/00 ,  H01L41/22

    CPC分类号： H02N2/007 ,  Y10T29/42

    摘要： [Purpose] The present invention relates to an ultrasonic motor having a stator which includes a piezoelectric element for moving a rotor in a prescribed direction by applying a predetermined ultrasonic voltage thereto, and the rotor which is fixed to the stator by a frictional force, and a method for manufacturing an ultrasonic motor, and it has for its purpose to attain decrease of dust appearance by enhancement of a wear resistance, a different hardness, or the like in such a way that a contact part of at least either of a stator and a rotor which constitute the ultrasonic motor is irradiated with ions.[Constitution] An ultrasonic motor characterized in that either or both of contact parts of a stator and a rotor is/are irradiated with ions, thereby to enhance a wear resistance of the contact part or parts.

    摘要翻译： 超声波电动机技术领域本发明涉及具有定子的超声波电动机，该定子包括：通过施加规定的超声波电压使规定的方向上的转子向规定的方向移动的压电元件和通过摩擦力固定在定子上的转子， 一种超声波马达的制造方法，其目的是通过提高耐磨性，不同的硬度等来降低灰尘外观，使得定子和 用离子照射构成超声波马达的转子。 [结构]一种超声波马达，其特征在于，定子和转子的接触部中的任一个或两者被离子照射，从而提高接触部件的耐磨性。

    Material for aneurysm curing
    9.
    发明申请
    Material for aneurysm curing 审中-公开
    动脉瘤固化材料

    公开(公告)号：US20070185570A1

    公开(公告)日：2007-08-09

    申请号：US10568694

    申请日：2004-08-18

    申请人： Hiroshi Ujiie ,  Yoshiaki Suzuki ,  Masaya Iwaki ,  Takanori Uchida

    发明人： Hiroshi Ujiie ,  Yoshiaki Suzuki ,  Masaya Iwaki ,  Takanori Uchida

    IPC分类号： A61F2/06

    CPC分类号： A61L31/04 ,  A61K31/00 ,  A61L2400/18 ,  A61L2430/36

    摘要： It is an object of the present invention to provide a polymer material, the histocompatibility of which has been improved by irradiation of ion beam, which prevents an aneurysm having a risk of rupture from actually rupturing. The present invention provides a material for treating aneurysms, which is composed of a polymer material containing carbon as a constitutional element, and which is produced by modifying at least a portion of the surface thereof by ion bombardment.

    摘要翻译： 本发明的一个目的是提供一种通过离子束的照射改善了组织相容性的聚合物材料，其防止了具有破裂风险的动脉瘤的实际破裂。 本发明提供一种治疗动脉瘤的材料，其由含有碳作为构成元素的高分子材料构成，其通过离子轰击改性其表面的至少一部分而制成。