公开(公告)号：US20100321004A1

公开(公告)日：2010-12-23

申请号：US12870463

申请日：2010-08-27

申请人： Imants LAUKS ,  Andrzej MACZUSZENKO

发明人： Imants LAUKS ,  Andrzej MACZUSZENKO

IPC分类号： G01R1/04 ,  B32B37/00

CPC分类号： G01N27/26 ,  B01L3/502707 ,  B01L3/502715 ,  B01L3/502723 ,  B01L3/50273 ,  B01L3/502738 ,  B01L7/00 ,  B01L2200/025 ,  B01L2200/0689 ,  B01L2200/148 ,  B01L2200/16 ,  B01L2300/0645 ,  B01L2300/0816 ,  B01L2300/0887 ,  B01L2300/1805 ,  B01L2300/1827 ,  B01L2400/0481 ,  B01L2400/0487 ,  B01L2400/0683 ,  B32B37/06 ,  B32B37/10 ,  B32B38/04 ,  B32B2038/047 ,  B32B2425/00 ,  G01N27/3272 ,  G01N27/403 ,  G01N2021/0193 ,  G01N2035/00148

摘要： The present invention relates to diagnostic devices incorporating electrode modules and fluidics for performing chemical analyses. The invented devices consist of a sensor array formed on an electrode module, the sensor array being contained within a fluidic housing. The electrode module is a laminate of a perforated epoxy foil and a photo-formed metal foil with sensor membranes deposited into the perforations. The fluidic housing is an element consisting of a plastic card-like body with fluidic conduits and a sealed fluid reservoir contained in a foil-lined cavity.

摘要翻译： 本发明涉及包含用于进行化学分析的电极模块和流体学的诊断装置。 本发明的装置由形成在电极模块上的传感器阵列组成，传感器阵列包含在流体壳体内。 电极模块是穿孔环氧箔和光致成形金属箔的叠层，传感膜沉积在穿孔中。 流体外壳是由具有流体导管的塑料卡状体和包含在箔衬里腔中的密封流体储存器组成的元件。

公开(公告)号：US20100252428A1

公开(公告)日：2010-10-07

申请号：US12819273

申请日：2010-06-21

申请人： Imants LAUKS ,  Anca VARLAN ,  Alexandra OUSSOVA ,  Michael BALES

发明人： Imants LAUKS ,  Anca VARLAN ,  Alexandra OUSSOVA ,  Michael BALES

IPC分类号： G01N27/26 ,  B05D5/00

CPC分类号： G01N27/307 ,  B01L3/5027 ,  B01L3/502715 ,  B01L2200/025 ,  B01L2200/148 ,  B01L2300/0645 ,  B01L2300/0825 ,  B01L2300/0883 ,  B01L2300/0887 ,  B01L2400/0487 ,  B01L2400/0683

摘要： The present invention relates to planar electrochemical sensors with membrane coatings used to perform chemical analyses. The object of this invention is to provide unit-use disposable sensors of very simple and inexpensive construction, preferably with only a single membrane coating on an electrode. The invented devices are potentiometric salt-bridge reference electrodes and dissolved gas sensors constructed with a heterogeneous membrane coating of a conductor. The heterogeneous membrane, which is an intimate admixture of a hydrophobic and a hydrophilic compartment, concurrently supports constrained transport of non-volatile species through its hydrophilic compartment and rapid gas and water vapor transport through its hydrophobic compartment.

摘要翻译： 本发明涉及具有用于进行化学分析的膜涂层的平面电化学传感器。 本发明的目的是提供非常简单和便宜的结构的单元使用一次性传感器，优选地在电极上仅具有单个膜涂层。 本发明的器件是电位计的盐桥参考电极和由导体的非均相膜涂层构成的溶解气体传感器。 疏水隔离层和亲水隔室的紧密混合物的非均相膜同时支持非挥发性物质通过其亲水隔室的受限运输，并通过其疏水隔室快速的气体和水蒸汽输送。

公开(公告)号：US20100202926A1

公开(公告)日：2010-08-12

申请号：US12718139

申请日：2010-03-05

申请人： Imants LAUKS ,  Raymond J. PIERCE ,  James WOJTYK ,  Benoit R. BERGEVIN

发明人： Imants LAUKS ,  Raymond J. PIERCE ,  James WOJTYK ,  Benoit R. BERGEVIN

IPC分类号： G01N27/00 ,  F04F99/00

CPC分类号： B01L3/50273 ,  B01L2200/0673 ,  B01L2200/10 ,  B01L2300/0816 ,  B01L2400/0406 ,  B01L2400/0418 ,  F04B19/006 ,  Y10T436/2575

摘要： Devices with lateral flow elements and integral fluidics are disclosed. The integral fluidics consist of injector pumps comprised of fluidic elements under instrument control. The fluidic element of an injector pump is fluidically connected to lateral flow elements and can be used to control fluid entry into containment chambers referred to as micro-reactors. The lateral flow elements comprise conductor elements that can be used for sample application and transport of analyte contained in the sample to the micro-reactor. Fluidic transport through the fluidic element of the injector pump is under instrument-control. Both the lateral flow element and the fluidic element may contain chemical entities incorporated along their length. The chemical reactions that can be used for analyte detection using the devices are described. Also described are methods of manufacture of these devices.

摘要翻译： 公开了具有侧向流动元件和整体流体的装置。 积分流体由在仪器控制下由流体元素组成的喷射泵组成。 注射器泵的流体元件流体连接到侧向流动元件，并且可以用于控制流体进入称为微反应器的容纳室中。 横向流动元件包括导体元件，其可以用于将样品中包含的分析物的样品应用和运送到微反应器。 通过注射泵的流体元件的流体传输是在仪器控制下。 侧流元件和流体元件都可以包含沿其长度并入的化学物质。 描述了可用于使用装置进行分析物检测的化学反应。 还描述了这些装置的制造方法。

公开(公告)号：US20070170062A1

公开(公告)日：2007-07-26

申请号：US11697116

申请日：2007-04-05

申请人： Imants LAUKS

发明人： Imants LAUKS

IPC分类号： G01N27/00

CPC分类号： B01L3/50273 ,  B01J2219/00783 ,  B01J2219/00831 ,  B01J2219/00853 ,  B01J2219/0086 ,  B01L3/502707 ,  B01L3/502753 ,  B01L2200/12 ,  B01L2200/16 ,  B01L2300/0645 ,  B01L2300/0825 ,  B01L2300/10 ,  B01L2400/0415 ,  B01L2400/0418 ,  G01N2035/00158

摘要： Devices with electrokinetic elements are disclosed as well as their method of microfabrication for use in micro-scale analysis, mixture separation and reaction. The devices consist of solid hydrophilic-matrix films that have been microfabricated into a variety of micro-scale structures. These structures include hydrophilic-matrix conductors for electrokinetic species transport and separation. They also include hydrophilic-matrix cladding containing chemical species adjacent to either an open conduit or a hydrophilic matrix conductor. Also described are other integrated microstructures consisting of hydrophilic-matrix materials such as micro-reaction zones for retaining chemical species for on-chip chemical reactions and integrated detection structures for on-chip species detection. In general, a hydrophilic matrix on a substrate functions as a conductor that is covered by an electrically insulating, preferably water permeable material.

摘要翻译： 公开了具有电动元件的装置以及其用于微尺度分析，混合物分离和反应的微细加工方法。 这些装置由已经微加工成各种微尺度结构的固体亲水基质膜组成。 这些结构包括用于电动物质输送和分离的亲水基质导体。 它们还包括含有与开放导管或亲水基质导体相邻的化学物质的亲水基质包层。 还描述了由亲水基质材料如用于保留用于片上化学反应的化学物质的微反应区和用于片上物种检测的集成检测结构组成的其它集成微结构。 通常，衬底上的亲水基质用作被电绝缘，优选水可渗透材料覆盖的导体。