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90 条记录 (耗时 0.028 秒)

    Catalytic synthesis of N-alkylated anilines from olefins and anilines
    1.
    发明授权
    Catalytic synthesis of N-alkylated anilines from olefins and anilines 失效
    从烯烃和苯胺催化合成N-烷基化苯胺

    公开(公告)号：US06222073B1

    公开(公告)日：2001-04-24

    申请号：US09600267

    申请日：2000-07-03

    申请人： Jürgen Herwig ,  Matthias Beller ,  Claudia Breindl ,  Harald Trauthwein ,  Elisabeth Eichberger ,  Anton Eichberger

    发明人： Jürgen Herwig ,  Matthias Beller ,  Claudia Breindl ,  Harald Trauthwein ,  Elisabeth Eichberger ,  Anton Eichberger

    IPC分类号： C07C20900

    CPC分类号： C07C213/00 ,  C07C209/60 ,  C07C211/48 ,  C07C217/84

    摘要： Process for the preparation of an N-arylethylaniline of the formula (I) Ar—N(R1)2-n(CHR2CHR3Ar′)n  (I) by reacting an aromatic olefin of the formula (II) Ar′CR3=CHR2  (II) with an aniline of the formula (III) Ar—N(R1)2-n(H)n  (III) in an inert solvent in the presence of at least one basic catalyst selected from the group consisting of alkali metal alcoholates and alkaline earth metal alcoholates or alkali metal amides and alkaline earth metal amides, where, in the formulae (I) to (III), Ar and Ar′, independently of one another, are an aryl radical selected from the group consisting of the fused and nonfused C6-C22-aromatics and of the fused or nonfused C5-C22heteroaromatics which have at least one nitrogen, oxygen or sulfur atom in the ring; R1, R2 and R3, independently of one another, are a hydrogen atom, a C1-C8-alkyl radical or an aryl radical Ar; and n is the number 1 or 2.

    摘要翻译： 通过使式（II）的芳族烯烃与式（III）的苯胺在惰性溶剂中在至少一种选自以下的碱式催化剂的存在下反应制备式（I）的N-芳基乙基苯胺的方法： 由碱金属醇化物和碱土金属醇化物或碱金属氨化物和碱土金属酰胺组成的组中，其中在式（I）至（III）中，Ar和Ar'彼此独立地为选自 由稠合和未填充的C 6 -C 22芳族化合物和在环中具有至少一个氮，氧或硫原子的稠合或未稠合的C 5 -C 22杂原子取代基组成的组; R 1，R 2和R 3彼此独立地是 氢原子，C1-C8-烷基或芳基Ar; andn是数字1或2。

    Base-catalyzed synthesis of 1-aryl-4-(aryl ethyl)piperazines from aromatic olefins and 1-arylpiperazines
    3.
    发明授权
    Base-catalyzed synthesis of 1-aryl-4-(aryl ethyl)piperazines from aromatic olefins and 1-arylpiperazines 失效
    芳基烯烃和1-芳基哌嗪的碱基催化合成1-芳基-4-（芳基乙基）哌嗪

    公开(公告)号：US06313297B1

    公开(公告)日：2001-11-06

    申请号：US09600274

    申请日：2000-07-13

    申请人： Jürgen Herwig ,  Matthias Beller ,  Claudia Breindl

    发明人： Jürgen Herwig ,  Matthias Beller ,  Claudia Breindl

    IPC分类号： C07D29502

    CPC分类号： C07D295/023 ,  C07D295/073 ,  C07D295/096

    摘要： A process for preparing a 1-aryl-4-(arylethyl)piperazine of the formula (I) by reacting a 1-arylpiperazine of the formula (II) with an aromatic olefin of the formula (III) Ar′CR1═CHR2  (III) in an inert solvent in the presence of at least one basic catalyst, where in the formulae (I) to (III) Ar and Ar′ independently of one another are an aryl radical, selected from the group of the fused and unfused C6-C22-aromatics and the fused or unfused C5-C22-heteroaromatics which have at least one nitrogen, oxygen or sulfur atom in the ring; and R1 and R2 independently of one another are a hydrogen atom, a C1-C8-alkyl radical or an aryl radical Ar.

    摘要翻译： 在惰性溶剂中，使式（I）的1-芳基-4-（芳基乙基）哌嗪通过式（II）的1-芳基哌嗪与式（III）的芳族烯烃在惰性溶剂中反应来制备式 至少一种碱性催化剂，其中在式（I）至（III）中Ar和Ar'彼此独立地为芳基，其选自稠合和未融合的C6-C22-芳族化合物和稠合或未融合的 在环中具有至少一个氮，氧或硫原子的C5-C22-杂芳族化合物; 并且R 1和R 2彼此独立地是氢原子，C 1 -C 8 - 烷基或芳基Ar。

    Process for catalytically preparing aromatic or heteroaromatic nitriles
    8.
    发明授权
    Process for catalytically preparing aromatic or heteroaromatic nitriles 有权
    用于催化制备芳族或杂芳族腈的方法

    公开(公告)号：US08314243B2

    公开(公告)日：2012-11-20

    申请号：US11986398

    申请日：2007-11-21

    申请人： Nikolaus Müller ,  Wolfgang Mägerlein ,  Alain Cotté ,  Matthias Beller ,  Thomas Schareina ,  Alexander Zapf

    发明人： Nikolaus Müller ,  Wolfgang Mägerlein ,  Alain Cotté ,  Matthias Beller ,  Thomas Schareina ,  Alexander Zapf

    IPC分类号： C07D211/78 ,  A01N43/38

    CPC分类号： C07B37/04 ,  C07C1/26 ,  C07C17/10 ,  C07C2529/40 ,  C07D213/61 ,  C07C9/00 ,  C07C19/075

    摘要： A process is described for catalytically preparing optionally substituted aromatic or heteroaromatic nitrites of the general formula (I) Ar—CN  (I) by reacting the corresponding aryl halides of the general formula (II) Ar—X  (II) in which X is chlorine, bromine, iodine, triflate, nonaflate, mesylate or tosylate and Ar is an optionally substituted aromatic or heteroaromatic radical, characterized in that the reaction is performed in the presence of a palladium compound, a phosphine of the general formula (III) or (IV) where R is an alkyl radical and R′, R″ and R′″ are each an alkyl radical or an aryl radical or heteroaryl radical and A is an alkylene or arylene radical, and potassium hexacyanoferrate(II) or potassium hexacyanoferrate(III), optionally in a solvent and optionally with addition of a base.

    摘要翻译： 描述了通过使通式（II）Ar-X（II）的相应芳基卤反应其中X为氯的方法催化制备通式（I）Ar-CN（I）的任选取代的芳族或杂芳族亚硝酸盐的方法 溴，碘，三氟甲磺酸酯，壬酸酯，甲磺酸酯或甲苯磺酸酯，Ar是任选取代的芳族或杂芳族基团，其特征在于反应在钯化合物，通式（III）或（IV） ）其中R是烷基，R'，R“和R”“各自是烷基或芳基或杂芳基，A是亚烷基或亚芳基，六氰基铁酸钾（II）或六氰基铁酸钾（III） ，任选地在溶剂中和任选地加入碱。