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    System and method for determining pulmonary performance from transthoracic impedance measures
    1.
    发明授权
    System and method for determining pulmonary performance from transthoracic impedance measures 有权
    用于确定经胸阻抗措施的肺功能的系统和方法

    公开(公告)号：US08795189B2

    公开(公告)日：2014-08-05

    申请号：US12029422

    申请日：2008-02-11

    申请人： Quan Ni ,  Jesse W. Hartley ,  Kent Lee ,  Jeffrey E. Stahmann

    发明人： Quan Ni ,  Jesse W. Hartley ,  Kent Lee ,  Jeffrey E. Stahmann

    IPC分类号： A61B5/08

    CPC分类号： A61B5/0809 ,  A61B5/0002 ,  A61B5/0535 ,  A61N1/36521 ,  G06F19/3418

    摘要： A system and method for determining pulmonary performance from transthoracic impedance measures is provided. Transthoracic impedance measures collected by an implantable medical device are correlated to pulmonary functional measures. The pulmonary functional measures are grouped by respiratory pattern. Pulmonary performance is evaluated. Differences are determined by comparing the pulmonary functional measures for each respiratory pattern to the pulmonary functional measures for at least one previous respiratory pattern. A trend is identified from the differences. An alert is generated upon sufficient deviation of the trend from a threshold criteria.

    摘要翻译： 提供了一种通过经胸阻抗测量来确定肺功能的系统和方法。 由可植入医疗器械收集的经胸阻抗测量与肺功能测量相关。 肺功能测量按呼吸模式分组。 评估肺功能。 通过将每个呼吸模式的肺功能测量与至少一个之前的呼吸模式的肺功能测量进行比较来确定差异。 从差异中确定出一个趋势。 在趋势与阈值标准的充分偏差之后产生警报。

    Cardiac pacing controlled via respiration therapy device
    2.
    发明授权
    Cardiac pacing controlled via respiration therapy device 失效
    通过呼吸治疗装置控制心脏起搏

    公开(公告)号：US08655446B2

    公开(公告)日：2014-02-18

    申请号：US11986886

    申请日：2007-11-27

    申请人： Jeffrey E. Stahmann ,  Jesse W. Hartley ,  Kent Lee ,  Quan Ni

    发明人： Jeffrey E. Stahmann ,  Jesse W. Hartley ,  Kent Lee ,  Quan Ni

    IPC分类号： A61N1/365

    CPC分类号： A61N1/3601 ,  A61N1/36514 ,  A61N1/36542 ,  A61N1/36578 ,  G06F19/00

    摘要： Methods and systems involve adjusting cardiac pacing based on information acquired via a respiratory therapy device. A medical system includes a respiratory therapy device having one or more sensors and a therapy delivery unit. The one or more sensors are configured to sense respiration cycles. The therapy delivery unit is configured to deliver an external respiratory therapy to the patient. The medical system also includes a pulse generator configured to deliver cardiac pacing pulses to the patient. A controller is coupled to the one or more sensors and the pulse generator. The control unit configured to adjust a cardiac pacing rate based on the patient's respiration cycles.

    摘要翻译： 方法和系统涉及根据通过呼吸治疗装置获取的信息来调节心脏起搏。 医疗系统包括具有一个或多个传感器和治疗递送单元的呼吸治疗装置。 一个或多个传感器被配置成感测呼吸循环。 治疗递送单元被配置为向患者输送外部呼吸治疗。 医疗系统还包括脉冲发生器，其被配置为向患者传送心脏起搏脉冲。 控制器耦合到一个或多个传感器和脉冲发生器。 所述控制单元被配置为基于所述患者的呼吸周期来调节心脏起搏速率。

    System and Method for Characterizing Patient Respiration
    3.
    发明申请
    System and Method for Characterizing Patient Respiration 审中-公开
    用于表征患者呼吸的系统和方法

    公开(公告)号：US20100174207A1

    公开(公告)日：2010-07-08

    申请号：US12723998

    申请日：2010-03-15

    申请人： Kent Lee ,  Quan Ni ,  Jesse W. Hartley ,  John D. Hatlestad ,  Jeffrey E. Stahmann

    发明人： Kent Lee ,  Quan Ni ,  Jesse W. Hartley ,  John D. Hatlestad ,  Jeffrey E. Stahmann

    IPC分类号： A61B5/08

    CPC分类号： A61B5/4806 ,  A61B5/0205 ,  A61B5/08 ,  A61B5/082 ,  A61N1/08

    摘要： Patient respiration may be characterized using a marked respiration waveform involving a respiration waveform annotated with symbols, markers or other indicators representing one or more respiration characteristics. A respiration waveform may be acquired by sensing a physiological parameter modulated by respiration. A marked respiration waveform may be generated based on the acquired respiration waveform and one or more detected respiration waveform characteristics and/or respiration-related conditions. One or more components used to generate the marked respiratory waveform may be fully or partially implantable.

    摘要翻译： 患者呼吸可以使用标示的呼吸波形来表征，该呼吸波形涉及用符号，标记或代表一个或多个呼吸特征的其它指示符注释的呼吸波形。 可以通过感测由呼吸调制的生理参数来获取呼吸波形。 可以基于所获取的呼吸波形和一个或多个检测到的呼吸波形特征和/或呼吸相关条件来生成标记的呼吸波形。 用于产生标记的呼吸波形的一个或多个组件可以是完全或部分可植入的。

    System and method for detecting an involuntary muscle movement disorder
    5.
    发明授权
    System and method for detecting an involuntary muscle movement disorder 有权
    用于检测不自主肌肉运动障碍的系统和方法

    公开(公告)号：US07616988B2

    公开(公告)日：2009-11-10

    申请号：US10939639

    申请日：2004-09-13

    申请人： Jeffrey E. Stahmann ,  Jesse W. Hartley ,  Kent Lee ,  Quan Ni

    发明人： Jeffrey E. Stahmann ,  Jesse W. Hartley ,  Kent Lee ,  Quan Ni

    IPC分类号： A61B5/04 ,  A61B5/117 ,  A61B5/103

    CPC分类号： A61B5/0488 ,  A61B5/1107 ,  A61B5/4806 ,  A61B5/4809 ,  A61B5/4812 ,  A61B5/6869 ,  A61B2505/05 ,  A61N1/36003

    摘要： Methods and systems are directed to evaluating a pathological condition and involve acquiring muscle movement signals, such as electromyogram (EMG) or accelerometer signals, and detecting the presence of the pathological condition. Methods and systems also provide for detecting sleep-related involuntary muscle disorders and non sleep-related involuntary muscle disorders using muscle movement signals. Drug therapy, transcutaneous electric nerve stimulation therapy, or other therapy may be delivered to treat a detected or diagnosed involuntary muscle disorder.

    摘要翻译： 方法和系统旨在评估病理状况，并涉及获取肌肉运动信号，如肌电图（EMG）或加速度计信号，并检测病理状况的存在。 方法和系统还提供使用肌肉运动信号来检测与睡眠相关的非自主性肌肉疾病和非睡眠相关的非自主性肌肉障碍。 药物治疗，经皮电神经刺激治疗或其他治疗可以被递送以治疗检测到或诊断的非自愿肌肉疾病。

    System And Method For Determining Pulmonary Performance From Transthoracic Impedance Measures
    7.
    发明申请
    System And Method For Determining Pulmonary Performance From Transthoracic Impedance Measures 有权
    用于确定胸腔阻塞措施的肺功能的系统和方法

    公开(公告)号：US20080132802A1

    公开(公告)日：2008-06-05

    申请号：US12029422

    申请日：2008-02-11

    申请人： Quan Ni ,  Jesse W. Hartley ,  Kent Lee ,  Jeffrey E. Stahmann

    发明人： Quan Ni ,  Jesse W. Hartley ,  Kent Lee ,  Jeffrey E. Stahmann

    IPC分类号： A61B5/085

    CPC分类号： A61B5/0809 ,  A61B5/0002 ,  A61B5/0535 ,  A61N1/36521 ,  G06F19/3418

    摘要： A system and method for determining pulmonary performance from transthoracic impedance measures is provided. Transthoracic impedance measures collected by an implantable medical device are correlated to pulmonary functional measures. The pulmonary functional measures are grouped by respiratory pattern. Pulmonary performance is evaluated. Differences are determined by comparing the pulmonary functional measures for each respiratory pattern to the pulmonary functional measures for at least one previous respiratory pattern. A trend is identified from the differences. An alert is generated upon sufficient deviation of the trend from a threshold criteria.

    摘要翻译： 提供了一种通过经胸阻抗测量来确定肺功能的系统和方法。 由可植入医疗器械收集的经胸阻抗测量与肺功能测量相关。 肺功能测量按呼吸模式分组。 评估肺功能。 通过将每个呼吸模式的肺功能测量与至少一个之前的呼吸模式的肺功能测量进行比较来确定差异。 从差异中确定出一个趋势。 在趋势与阈值标准的充分偏差之后产生警报。

    Detection of disordered breathing
    9.
    发明授权
    Detection of disordered breathing 有权
    检测无序呼吸

    公开(公告)号：US08475388B2

    公开(公告)日：2013-07-02

    申请号：US12847711

    申请日：2010-07-30

    申请人： Quan Ni ,  John D. Hatlestad ,  Jesse W. Hartley ,  Jeffrey E. Stahmann ,  Jaeho Kim ,  Kent Lee

    发明人： Quan Ni ,  John D. Hatlestad ,  Jesse W. Hartley ,  Jeffrey E. Stahmann ,  Jaeho Kim ,  Kent Lee

    IPC分类号： A61B5/08

    CPC分类号： A61B5/4818 ,  A61B5/0205 ,  A61B5/4806 ,  A61B5/4809 ,  A61B5/7264

    摘要： Devices and methods for detecting disordered breathing involve determining that the patient is asleep and sensing one or more signals associated with disordered breathing indicative of sleep-disordered breathing while the patient is asleep. Sleep-disordered breathing is detected using the sensed signals associated with disordered breathing. The sensed signals associated with disordered breathing may also be used to acquire a respiration pattern of one or more respiration cycles. Characteristics of the respiration pattern are determined. The respiration pattern is classified as a disordered breathing episode based on the characteristics of the respiration pattern. One or more processes involved in the detection of disordered breathing are performed using an implantable device.

    摘要翻译： 用于检测无序呼吸的装置和方法涉及确定患者睡着并且感测与患者睡着时指示睡眠呼吸紊乱的无序呼吸相关联的一个或多个信号。 使用与无序呼吸相关的感测信号来检测睡眠呼吸障碍。 与无序呼吸相关联的感测信号也可用于获取一个或多个呼吸循环的呼吸模式。 确定呼吸模式的特征。 根据呼吸模式的特点，呼吸模式被分类为无序呼吸发作。 使用可植入装置进行涉及无序呼吸检测的一个或多个过程。

    Automatic activation of medical processes
    10.
    发明授权
    Automatic activation of medical processes 失效
    自动激活医疗过程

    公开(公告)号：US08380296B2

    公开(公告)日：2013-02-19

    申请号：US12649753

    申请日：2009-12-30

    申请人： Kent Lee ,  Jeffrey E. Stahmann ,  Jesse W. Hartley ,  Quan Ni

    发明人： Kent Lee ,  Jeffrey E. Stahmann ,  Jesse W. Hartley ,  Quan Ni

    IPC分类号： A61B5/04

    CPC分类号： A61N1/3601 ,  A61B5/04012 ,  A61B5/1107 ,  A61B5/4094 ,  A61B5/4818 ,  A61B5/6869 ,  A61B2505/09 ,  A61M16/024 ,  A61M16/10 ,  A61M2016/0039 ,  A61M2016/0042 ,  A61M2205/3561 ,  A61M2205/3584 ,  A61M2230/04 ,  A61M2230/10 ,  A61M2230/63 ,  A61N1/3611 ,  A61N1/36114 ,  A61N1/36135 ,  A61N1/36514

    摘要： Systems and methods involve automatic activation, de-activation or modification of therapies or other medical processes based on brain state. A medical system includes a sensor system having one or more sensors configured to sense signals related to the brain state of the patient. A brain state analyzer detects various brain states, including sleep stage and/or brain seizures. A controller uses the brain state detection information to control a medical system configured to perform at least one respiratory or cardiac process. Methods involve sensing signals related to brain state and determining the brain state of a patient based on the sensed signals. At least one respiratory or cardiac medical process is controlled based on the patient's brain state.

    摘要翻译： 系统和方法涉及基于脑状态的治疗或其他医疗过程的自动激活，去激活或修饰。 医疗系统包括具有一个或多个传感器的传感器系统，该传感器被配置为感测与患者的脑状态相关的信号。 脑状态分析仪检测各种脑状态，包括睡眠阶段和/或脑癫痫发作。 控制器使用脑状态检测信息来控制被配置为执行至少一个呼吸或心脏过程的医疗系统。 方法涉及感测与脑状态相关的信号，并且基于感测到的信号来确定患者的大脑状态。 至少一个呼吸或心脏医疗过程是根据患者的大脑状态进行控制的。