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    Bioactive Bone Graft Substitutes
    1.
    发明申请
    Bioactive Bone Graft Substitutes 审中-公开
    生物活性骨移植替代物

    公开(公告)号：US20130331898A1

    公开(公告)日：2013-12-12

    申请号：US13493531

    申请日：2012-06-11

    申请人： Jevon Nyemscek ,  Vipin Kunjachan ,  Allison Adams

    发明人： Jevon Nyemscek ,  Vipin Kunjachan ,  Allison Adams

    IPC分类号： A61K33/42 ,  A61P19/00 ,  A61B17/88

    CPC分类号： A61L27/54 ,  A61L24/0005 ,  A61L24/001 ,  A61L24/0015 ,  A61L24/0036 ,  A61L24/0089 ,  A61L27/3804 ,  A61L27/446 ,  A61L27/50 ,  A61L27/56 ,  A61L2300/412 ,  A61L2430/02 ,  C08L89/06

    摘要： Provided are synthetic bone graft substitutes that include bioactive glass and a carrier. Synthetic bone graft substitutes may include bioactive glass, glycerol and polyethylene glycol. Also provided are bone graft substitutes that include collagen and bioactive glass particles. Example bone graft substitutes may include collagen and bioactive glass particles. Other example embodiments may include Type I Bovine Collagen, an angiogenic agent, such as hyaluronic acid, and bioactive glass. Further provided are methods that include administering the present bone graft substitutes to a mammal, e.g., by surgical insertion of the bone graft substitute into the mammal, either alone or in conjunction with one or more implant devices. Further provided are kits that include the present bone grafts.

    摘要翻译： 提供包括生物活性玻璃和载体的合成骨移植替代物。 合成骨移植物替代物可以包括生物活性玻璃，甘油和聚乙二醇。 还提供了包括胶原和生物活性玻璃颗粒的骨移植替代物。 骨移植替代物可以包括胶原和生物活性玻璃颗粒。 其它示例性实施方案可以包括I型牛胶原，血管生成剂，例如透明质酸和生物活性玻璃。 还提供了方法，其包括将本发明的骨移植物替代物施用于哺乳动物，例如通过将骨移植物替代物手术插入到哺乳动物中，单独或与一个或多个植入装置结合。 还提供了包括目前骨移植物的试剂盒。

    Bioactive bone graft substitutes
    2.
    发明授权
    Bioactive bone graft substitutes 有权

    公开(公告)号：US10207027B2

    公开(公告)日：2019-02-19

    申请号：US13493531

    申请日：2012-06-11

    申请人： Jevon Nyemscek ,  Vipin Kunjachan ,  Allison Adams

    发明人： Jevon Nyemscek ,  Vipin Kunjachan ,  Allison Adams

    IPC分类号： A61K35/32 ,  A61K38/18 ,  A61L27/44 ,  A61L27/54 ,  A61L27/38 ,  A61L27/50 ,  A61L27/56 ,  A61L24/00

    摘要： Provided are synthetic bone graft substitutes that include bioactive glass and a carrier. Synthetic bone graft substitutes may include bioactive glass, glycerol and polyethylene glycol. Also provided are bone graft substitutes that include collagen and bioactive glass particles. Example bone graft substitutes may include collagen and bioactive glass particles. Other example embodiments may include Type I Bovine Collagen, an angiogenic agent, such as hyaluronic acid, and bioactive glass. Further provided are methods that include administering the present bone graft substitutes to a mammal, e.g., by surgical insertion of the bone graft substitute into the mammal, either alone or in conjunction with one or more implant devices. Further provided are kits that include the present bone grafts.

    Biodegradable putty compositions and implant devices, methods, and kits relating to the same
    4.
    发明授权
    Biodegradable putty compositions and implant devices, methods, and kits relating to the same 有权
    可生物降解的油灰组合物和植入装置，方法和与之相关的试剂盒

    公开(公告)号：US08716363B2

    公开(公告)日：2014-05-06

    申请号：US13246999

    申请日：2011-09-28

    申请人： Vipin Kunjachan

    发明人： Vipin Kunjachan

    IPC分类号： A61F2/02 ,  A61K31/66 ,  A61K31/685

    CPC分类号： A61L27/14 ,  A61K35/32 ,  A61K38/00 ,  A61L27/18 ,  A61L27/3616 ,  A61L27/48 ,  A61L27/50 ,  A61L27/502 ,  A61L27/54 ,  A61L27/58 ,  A61L2300/414 ,  A61L2400/06 ,  A61L2430/02 ,  A61L2430/38 ,  C08L71/02

    摘要： Disclosed are phospholipid based compositions and implant devices, as well as methods and kits that include such compositions or components thereof. In particular, the present compositions include a polymer component such as a poloxamer or PEG component and a phospholipid component, such as a Phosal. The present compositions may include at least one additional component, such as granules, powder and/or particulates. The present compositions may further include one or more bone graft materials and/or active ingredients. The compositions may be used on their own or incorporated on or in a surgical implant.

    摘要翻译： 公开了基于磷脂的组合物和植入装置，以及包括这种组合物或组分的方法和试剂盒。 特别地，本发明的组合物包括聚合物组分如泊洛沙姆或PEG组分和磷脂组分，例如Phosal。 本发明的组合物可以包括至少一种另外的组分，例如颗粒，粉末和/或颗粒。 本发明的组合物还可以包括一种或多种骨移植材料和/或活性成分。 组合物可以单独使用或并入外科手术植入物中。

    Device for Stabilizing a Vertebral Joint and Method for Anterior Insertion Thereof
    7.
    发明申请
    Device for Stabilizing a Vertebral Joint and Method for Anterior Insertion Thereof 有权
    用于稳定椎体关节的装置及其前插入方法

    公开(公告)号：US20110190891A1

    公开(公告)日：2011-08-04

    申请号：US12699648

    申请日：2010-02-03

    申请人： Sean Suh ,  Jon Suh ,  Vipin Kunjachan ,  David C. Paul

    发明人： Sean Suh ,  Jon Suh ,  Vipin Kunjachan ,  David C. Paul

    IPC分类号： A61F2/44 ,  A61B17/86

    CPC分类号： A61B17/86 ,  A61F2/44

    摘要： A prosthetic device can be used as a prosthesis following a discectomy or a corpectomy. The prosthetic device includes two endplates with staggered motion limiting members. The device can be configured to allow six degrees of motion when comparing one endplate relative to the other. The endplates can be configured to fix the joint by changing the body held within the device and by adding a locking plate and fasteners. A method teaches how to insert a device to an intervertebral space via an anterior incision.

    摘要翻译： 假体装置可用作椎间盘切除术或切除术后的假体。 假体装置包括具有交错运动限制构件的两个端板。 当比较一个终板相对于另一个终板时，该装置可被配置为允许六个运动。 端板可以被配置为通过改变保持在装置内的主体并通过添加锁定板和紧固件来固定接头。 一种方法教导了如何通过前切口将装置插入椎间空间。

    Device for stabilizing a vertebral joint and method for anterior insertion thereof
    10.
    发明授权
    Device for stabilizing a vertebral joint and method for anterior insertion thereof 有权
    用于稳定椎骨关节的装置及其前插入方法

    公开(公告)号：US08556974B2

    公开(公告)日：2013-10-15

    申请号：US12699648

    申请日：2010-02-03

    申请人： Sean Suh ,  Jon Suh ,  Vipin Kunjachan ,  David C. Paul

    发明人： Sean Suh ,  Jon Suh ,  Vipin Kunjachan ,  David C. Paul

    IPC分类号： A61F2/44

    CPC分类号： A61B17/86 ,  A61F2/44

    摘要： A prosthetic device can be used as a prosthesis following a discectomy or a corpectomy. The prosthetic device includes two endplates with staggered motion limiting members. The device can be configured to allow six degrees of motion when comparing one endplate relative to the other. The endplates can be configured to fix the joint by changing the body held within the device and by adding a locking plate and fasteners. A method teaches how to insert a device to an intervertebral space via an anterior incision.

    摘要翻译： 假体装置可用作椎间盘切除术或切除术后的假体。 假体装置包括具有交错运动限制构件的两个端板。 当比较一个终板相对于另一个终板时，该装置可被配置为允许六个运动。 端板可以被配置为通过改变保持在装置内的主体并通过添加锁定板和紧固件来固定接头。 一种方法教导了如何通过前切口将装置插入椎间空间。