公开(公告)号：US08180460B2

公开(公告)日：2012-05-15

申请号：US11934627

申请日：2007-11-02

申请人： Jordan Matthew Nevsmith ,  Neil Hamilton Talbot ,  James Singleton Little ,  Brian V. Mech ,  Robert J. Greenberg ,  Qingfang Yao ,  Dao Min Zhou

发明人： Jordan Matthew Nevsmith ,  Neil Hamilton Talbot ,  James Singleton Little ,  Brian V. Mech ,  Robert J. Greenberg ,  Qingfang Yao ,  Dao Min Zhou

IPC分类号： A61N1/05

CPC分类号： A61N1/0543 ,  A61N1/0541 ,  A61N1/36046 ,  H05K1/028 ,  H05K1/0353 ,  H05K1/09 ,  H05K1/111 ,  H05K1/115 ,  H05K1/118 ,  H05K3/0014 ,  H05K3/0017 ,  H05K3/0041 ,  H05K3/06 ,  H05K3/188 ,  H05K3/22 ,  H05K3/388 ,  H05K3/4644 ,  H05K2201/0129 ,  H05K2201/0133 ,  H05K2201/0141 ,  H05K2201/0154 ,  Y10T29/49156 ,  Y10T29/49158

摘要： A flexible circuit electrode array with more than one layer of metal traces comprising: a polymer base layer; more than one layer of metal traces, separated by polymer layers, deposited on said polymer base layer, including electrodes suitable to stimulate neural tissue; and a polymer top layer deposited on said polymer base layer and said metal traces. Polymer materials are useful as electrode array bodies for neural stimulation. They are particularly useful for retinal stimulation to create artificial vision, cochlear stimulation to create artificial hearing, or cortical stimulation many purposes. The pressure applied against the retina, or other neural tissue, by an electrode array is critical. Too little pressure causes increased electrical resistance, along with electric field dispersion. Too much pressure may block blood flow.

摘要翻译： 一种具有多于一层金属迹线的柔性电路电极阵列，包括：聚合物基层; 沉积在所述聚合物基层上的多于一层由聚合物层隔开的金属痕迹层，包括适于刺激神经组织的电极; 以及沉积在所述聚合物基底层和所述金属迹线上的聚合物顶层。 聚合物材料可用作神经刺激的电极阵列体。 它们对视网膜刺激特别有用，用于创建人造视觉，人工耳蜗刺激以创建人造听觉或皮质刺激许多目的。 通过电极阵列对视网膜或其他神经组织施加的压力是至关重要的。 太小的压力会导致电阻增加以及电场分散。 太大的压力可能会阻止血液流动。

公开(公告)号：US08738149B2

公开(公告)日：2014-05-27

申请号：US13397604

申请日：2012-02-15

申请人： Qingfang Yao ,  Jordan Matthew Nevsmith ,  Neil Hamilton Talbot ,  James Singleton Little ,  Robert J. Greenberg

发明人： Qingfang Yao ,  Jordan Matthew Nevsmith ,  Neil Hamilton Talbot ,  James Singleton Little ,  Robert J. Greenberg

IPC分类号： A61N1/04

CPC分类号： A61N1/05 ,  A61N1/0541 ,  A61N1/0543 ,  B23K26/361 ,  B23K26/362

摘要： The invention involves a flexible circuit electrode array device comprising: a polymer layer; wherein the polymer layer includes one or more metal traces, an electrode array; one or more bond pads; and the electrode array is located on the opposite side of the polymer layer.The invention further involves a method for backside processing of a flexible circuit electrode device, comprising: applying polymer film on a substrate; processing the front side; releasing the polymer film from substrate; flipping over the polymer film and fixing it onto the substrate; processing the backside; and final releasing of the polymer film from the substrate.The invention further involves a method for backside processing of a flexible circuit electrode device, comprising: processing the front side without releasing the polymer; processing the backside by sacrificial substrate method, or by laser drilling method; and releasing the polymer film from the substrate.

摘要翻译： 本发明涉及一种柔性电路电极阵列器件，包括：聚合物层; 其中所述聚合物层包括一个或多个金属迹线，电极阵列; 一个或多个接合垫; 并且电极阵列位于聚合物层的相对侧上。 本发明还涉及一种用于柔性电路电极器件的背面处理的方法，包括：在基底上施加聚合物膜; 正面加工; 从基材中释放聚合物膜; 翻转在聚合物膜上并将其固定在基底上; 处理背面; 并从基底中最终释放聚合物膜。 本发明还涉及一种用于柔性电路电极器件的背面处理的方法，包括：处理前侧而不释放聚合物; 通过牺牲基板方法或通过激光钻孔方法处理背面; 并从基板上释放聚合物膜。

公开(公告)号：US20120150270A1

公开(公告)日：2012-06-14

申请号：US13397604

申请日：2012-02-15

申请人： Qingfang Yao ,  Jordan Matthew Nevsmith ,  Neil Hamilton Talbot ,  James Singleton Little ,  Robert J. Greenberg

发明人： Qingfang Yao ,  Jordan Matthew Nevsmith ,  Neil Hamilton Talbot ,  James Singleton Little ,  Robert J. Greenberg

IPC分类号： A61N1/05

CPC分类号： A61N1/05 ,  A61N1/0541 ,  A61N1/0543 ,  B23K26/361 ,  B23K26/362

摘要： The invention involves a flexible circuit electrode array device comprising: a polymer layer; wherein the polymer layer includes one or more metal traces, an electrode array; one or more bond pads; and the electrode array is located on the opposite side of the polymer layer.The invention further involves a method for backside processing of a flexible circuit electrode device, comprising: applying polymer film on a substrate; processing the front side; releasing the polymer film from substrate; flipping over the polymer film and fixing it onto the substrate; processing the backside; and final releasing of the polymer film from the substrate.The invention further involves a method for backside processing of a flexible circuit electrode device, comprising: processing the front side without releasing the polymer; processing the backside by sacrificial substrate method, or by laser drilling method; and releasing the polymer film from the substrate.

摘要翻译： 本发明涉及一种柔性电路电极阵列器件，包括：聚合物层; 其中所述聚合物层包括一个或多个金属迹线，电极阵列; 一个或多个接合垫; 并且电极阵列位于聚合物层的相对侧上。 本发明还涉及一种用于柔性电路电极器件的背面处理的方法，包括：在基底上施加聚合物膜; 正面加工; 从基材中释放聚合物膜; 翻转在聚合物膜上并将其固定在基底上; 处理背面; 并从基底中最终释放聚合物膜。 本发明还涉及一种用于柔性电路电极器件的背面处理的方法，包括：处理前侧而不释放聚合物; 通过牺牲基板方法或通过激光钻孔方法处理背面; 并从基板上释放聚合物膜。

公开(公告)号：US20120239126A1

公开(公告)日：2012-09-20

申请号：US13460495

申请日：2012-04-30

申请人： David Daomin Zhou ,  Robert J. Greenberg ,  Jordan Matthew Nevsmith ,  Boon-Khai Ng ,  James Singleton Little ,  Neil Hamilton Talbot ,  Satinderpall Singh Pannu ,  James Courtney Davidson ,  Phillipe John Tabada

发明人： David Daomin Zhou ,  Robert J. Greenberg ,  Jordan Matthew Nevsmith ,  Boon-Khai Ng ,  James Singleton Little ,  Neil Hamilton Talbot ,  Satinderpall Singh Pannu ,  James Courtney Davidson ,  Phillipe John Tabada

IPC分类号： A61F9/08 ,  B32B37/02 ,  A61N1/04

CPC分类号： A61N1/0543 ,  A61N1/0541 ,  H05K1/036 ,  H05K1/0393 ,  H05K1/118 ,  H05K3/28 ,  H05K2201/0133 ,  H05K2201/0195 ,  Y10T156/1002

摘要： A visual prosthesis which includes a hermetic package and flexible circuit electrode array is disclosed. The hermetic package includes electrode drivers and contacts. The flexible circuit electrode array includes a polymer base layer, metal traces, including electrodes suitable to stimulate visual neural tissue and bond pads bonded to contacts on the hermetic package, all deposited on the polymer base layer, a polymer top layer deposited on the polymer base layer and deposited on the metal traces, a partial or an entire coating of the polymer base layer and of the polymer top layer by a soft polymer that is softer than the polymer base layer; and the polymer base layer and the polymer top layer contain a plurality of aligned holes to facilitate bonding of the soft polymer.

摘要翻译： 公开了一种包括气密封装和柔性电路电极阵列的视觉假体。 密封包装包括电极驱动器和触点。 柔性电路电极阵列包括聚合物基层，金属迹线，包括适于刺激视觉神经组织的电极和粘合到密封封装上的触点的焊盘，全部沉积在聚合物基底层上，聚合物顶层沉积在聚合物基底上 并且通过比聚合物基底层更柔软的软质聚合物沉积在金属迹线上，聚合物基层和聚合物顶层的部分或全部涂层; 并且聚合物基层和聚合物顶层包含多个对准的孔以有助于软聚合物的结合。