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16 条记录 (耗时 0.04 秒)

    Microsphere and method for production thereof
    1.
    发明授权
    Microsphere and method for production thereof 失效
    微球及其生产方法

    公开(公告)号：US5635574A

    公开(公告)日：1997-06-03

    申请号：US617979

    申请日：1996-03-15

    申请人： Juuro Aoyagi ,  Toyoaki Suzuki ,  Reiko Kato ,  Masanori Nagata

    发明人： Juuro Aoyagi ,  Toyoaki Suzuki ,  Reiko Kato ,  Masanori Nagata

    IPC分类号： C08F2/06 ,  C08F2/04 ,  C08F220/54 ,  C08F226/02 ,  C08F222/38

    CPC分类号： C08F220/54

    摘要： A method for the production of a microsphere without use of a dispersion stabilizer is disclosed which permits the microsphere to be produced in the form of discrete particles readily treatable for purification. The method which produces this microsphere comprises the steps of dissolving in an organic solvent such as an alcohol a monomer mixture including an ethylenically unsaturated amide and 10 to 70% by weight, based on 100% by weight of said monomer mixture, of a cross-linking agent thereby preparing a mixed solution, keeping said mixed solution at a temperature in the range of from 30.degree. to 95.degree. C., and adding thereto at least one initiator selected from the group consisting of peroxide type initiators and azo type initiators in an amount such as to be contained therein at a final concentration in the range of from 1.times.10.sup.-5 to 8.times.10.sup.-2 mol/liter thereby inducing polymerization of said monomer mixture. The microsphere consequently obtained can be used as one kind of a substrate most suitable for the preparation of an affinity adsorbent serving ideally as a filler for use in affinity chromatography.

    摘要翻译： 公开了一种不使用分散稳定剂制备微球体的方法，该方法允许以容易处理以进行纯化的离散颗粒的形式制备微球体。 制备该微球的方法包括以下步骤：将基于100重量％的所述单体混合物溶解在有机溶剂如醇中，所述单体混合物包含烯属不饱和酰胺和10至70重量％的单体混合物， 连接剂，从而制备混合溶液，将所述混合溶液保持在30℃至95℃的温度范围内，并向其中加入至少一种选自过氧化物型引发剂和偶氮型引发剂的引发剂， 其含量为1×10 -5至8×10 -2 mol /升范围内的最终浓度，从而引起所述单体混合物的聚合。 由此获得的微球可以用作最适合于制备用作亲和色谱法的填料的亲和吸附剂的一种底物。

    Method for synthesis of anhydrothrombin
    3.
    发明授权
    Method for synthesis of anhydrothrombin 失效
    合成脱水凝血酶的方法

    公开(公告)号：US5939304A

    公开(公告)日：1999-08-17

    申请号：US88244

    申请日：1998-06-01

    申请人： Toyoaki Suzuki ,  Kazuya Hosokawa ,  Masanori Nagata

    发明人： Toyoaki Suzuki ,  Kazuya Hosokawa ,  Masanori Nagata

    IPC分类号： A61P7/02 ,  C07K1/113 ,  C07K14/745 ,  C12N9/74 ,  A61K38/48

    CPC分类号： C12N9/6429 ,  C12Y304/21005

    摘要： A method for a synthesis of anhydrothrombin is provided which features a short process, an easy procedure, and high yields.The method comprises(A) a step of causing an active serine residue site of thrombin to react with an inhibitor,(B) a step of performing an alkali treatment at a pH of not less than 11, and(C) a step of performing an operation of recovery, and carries out these steps sequentially in the order mentioned, and is characterized by causing at least the step of performing the operation of recovery to proceed in the presence of at least one compound selected from the group consisting of polyhydric alcohols and saccharides, and a salt or an amphoteric electrolyte.

    摘要翻译： 提供了一种合成脱水凝血酶的方法，其具有短程序，易操作和高产率。 该方法包括（A）使凝血酶的活性丝氨酸残基部位与抑制剂反应的步骤，（B）在pH不低于11的情况下进行碱处理的工序，（C） 回收操作，按顺序依次进行，其特征在于至少在至少一种选自多元醇和多元醇的化合物的存在下至少进行回收操作的步骤， 糖类，以及盐或两性电解质。

    Multiple compartment container
    4.
    发明授权
    Multiple compartment container 有权
    多隔间容器

    公开(公告)号：US08668971B2

    公开(公告)日：2014-03-11

    申请号：US10548622

    申请日：2004-03-11

    申请人： Toyoaki Suzuki ,  Koichi Miura

    发明人： Toyoaki Suzuki ,  Koichi Miura

    IPC分类号： B32B27/32

    CPC分类号： A61J1/2093 ,  A61J1/2024 ,  B32B7/04 ,  B32B7/06 ,  B32B7/10 ,  B32B7/12 ,  B32B7/14 ,  B32B27/08 ,  B32B27/325 ,  B32B2270/00 ,  B32B2307/30 ,  B32B2307/31 ,  B32B2307/748 ,  B32B2439/40 ,  B32B2439/46 ,  B32B2439/80 ,  B65D81/3266 ,  Y10T428/13 ,  Y10T428/1352 ,  Y10T428/1359

    摘要： A package with multiple chambers, wherein the inside of the package is partitioned into multiple chambers by a weak seal part(s) formed by sealing one sheet having a heat seal layer in at least one surface thereof and the other sheet having a heat seal layer in at least one surface thereof with the heat seal layers facing each other and sealing the peripheral edge parts thereof, and heat-pressing, from the outside of the package, a part of the inner surfaces of the walls of the package with the heat seal layers. The package is characterized in that both of two heat seal layers forming the inner surfaces of the walls include only a cyclic polyolefin resin as a resin ingredient.

    摘要翻译： 一种具有多个室的包装，其中通过在其至少一个表面中密封具有热密封层的一个片材而形成的弱密封部分将包装的内部分隔成多个室，而另一个片材具有热封层 在其至少一个表面中，热封层彼此面对并且密封其周边部分，并且从包装的外部将包装的壁的内表面的一部分用热封 层。 该封装的特征在于，形成壁的内表面的两个热封层都仅包含作为树脂成分的环状聚烯烃树脂。

    Multilayered liquid container
    7.
    发明授权
    Multilayered liquid container 有权
    多层液体容器

    公开(公告)号：US08309189B2

    公开(公告)日：2012-11-13

    申请号：US13057439

    申请日：2009-07-27

    申请人： Toyoaki Suzuki ,  Koichi Miura ,  Atsushi Mio

    发明人： Toyoaki Suzuki ,  Koichi Miura ,  Atsushi Mio

    IPC分类号： B29D22/00

    CPC分类号： B65D75/5883 ,  A61J1/10 ,  A61J1/1475 ,  B32B27/32 ,  Y10T428/1352

    摘要： A multilayered liquid container having a discharge port welded under specified conditions to a sealant, which is constituted of a resin comprising a cycloolefin resin as a main component. The discharge port is composed of: an innermost layer constituted of a resin comprising a cycloolefin as a main component; and a surface layer whose main part is constituted of a resin comprising a specific type of polyethylene as a main component. According to the present invention, there can be provided a multilayered liquid container, which can prevent an effective component of a content fluid from being adsorbed onto or penetrating through not only the container body, but also the resin constituting the discharge port, and enables high temperature sterilization treatment, coupled with the discharge port having high welded strength and drop strength.

    摘要翻译： 一种多层液体容器，其具有在特定条件下焊接到由包含环烯烃树脂作为主要成分的树脂构成的密封剂的排出口。 排出口由以下物质构成：由以环烯为主要成分的树脂构成的最内层; 以及其主要部分由包含特定类型的聚乙烯作为主要成分的树脂构成的表面层。 根据本发明，可以提供一种多层液体容器，其能够防止含量流体的有效成分不仅吸附到或穿过容器主体，也可以渗透到构成排出口的树脂上，并且能够高 与排出口相结合，焊接强度高，落下强度高。

    POURING PORT, METHOD FOR PRODUCING SAME AND CONTAINER FOR LIQUID PROVIDED WITH THE POURING PORT
    8.
    发明申请
    POURING PORT, METHOD FOR PRODUCING SAME AND CONTAINER FOR LIQUID PROVIDED WITH THE POURING PORT 有权
    浇口，用于生产它们的方法和用于在POURING PORT提供的液体的容器

    公开(公告)号：US20110266184A1

    公开(公告)日：2011-11-03

    申请号：US13143330

    申请日：2009-12-24

    申请人： Toyoaki Suzuki ,  Koichi Miura

    发明人： Toyoaki Suzuki ,  Koichi Miura

    IPC分类号： B65D85/00 ,  B32B37/06

    CPC分类号： A61J1/1475 ,  A61J1/10 ,  B29C65/08 ,  B29C66/712 ,  B32B7/12 ,  B32B27/08 ,  B32B27/304 ,  B32B27/306 ,  B32B27/32 ,  B32B27/34 ,  B32B27/36 ,  B32B2307/306 ,  B32B2307/31 ,  B32B2307/412 ,  B32B2307/50 ,  B32B2307/518 ,  B32B2307/546 ,  B32B2307/7244 ,  B32B2307/7246 ,  B32B2439/46 ,  B32B2439/80

    摘要： A pouring port of a container for liquid at one end of which a rubber stopper allowing the penetration of an injection needle therethrough is embedded, wherein: the pouring port is formed by welding a port part, at least the innermost layer of which forming the discharge channel thereof comprises a resin containing a COP-based resin as the main component, with a stopper body part, which holds the rubber stopper and comprises a resin containing a COP-based resin as the main component, via the resin layers containing the respective COP-based resins as the main component; and at least the resin constituting the stopper body part contains a rubber component in an amount of not more than 30% by mass, or has, in the main chain, a molecular structure represented by general formula (1) [wherein R represents a hydrogen atom or an organic group having 1 to 20 carbon atoms; and n represents an integer equal to or greater than 1] and contains a PE-based resin in an amount of 30% by mass or less, and/or contains an antioxidant in an amount of 0.1% by mass or more and not more than 1.0% by mass.

    摘要翻译： 一种用于液体的容器的倾倒口嵌入一个允许注射针穿过的橡胶塞，其中：所述倾倒口是通过焊接端口部分形成的，至少其最内层形成排出 其通道包括含有COP基树脂作为主要成分的树脂，具有塞体部分，其通过包含各COP的树脂层保持橡胶塞并包含含有COP基树脂作为主要成分的树脂 基树脂为主要成分; 并且至少构成塞体部的树脂含有不超过30质量％的橡胶组分，或者在主链中具有由通式（1）表示的分子结构[其中R表示氢 原子或碳原子数为1〜20的有机基团; n表示1以上的整数]，含有30质量％以下的PE系树脂，和/或含有0.1质量％以上且不大于 1.0质量％。

    Pouring port, method for producing same and container for liquid provided with the pouring port
    9.
    发明授权
    Pouring port, method for producing same and container for liquid provided with the pouring port 有权
    浇注口，生产方法和装有倾倒口的液体容器

    公开(公告)号：US08863967B2

    公开(公告)日：2014-10-21

    申请号：US13143330

    申请日：2009-12-24

    申请人： Toyoaki Suzuki ,  Koichi Miura

    发明人： Toyoaki Suzuki ,  Koichi Miura

    IPC分类号： B65D41/20 ,  A61J1/14 ,  B32B27/08 ,  B32B27/32 ,  B29C65/00 ,  B29C65/08 ,  A61J1/10

    CPC分类号： A61J1/1475 ,  A61J1/10 ,  B29C65/08 ,  B29C66/712 ,  B32B7/12 ,  B32B27/08 ,  B32B27/304 ,  B32B27/306 ,  B32B27/32 ,  B32B27/34 ,  B32B27/36 ,  B32B2307/306 ,  B32B2307/31 ,  B32B2307/412 ,  B32B2307/50 ,  B32B2307/518 ,  B32B2307/546 ,  B32B2307/7244 ,  B32B2307/7246 ,  B32B2439/46 ,  B32B2439/80

    摘要： A pouring port of a container for liquid at one end of which a rubber stopper allowing the penetration of an injection needle therethrough is embedded, wherein: the pouring port is formed by welding a port part, at least the innermost layer of which forming the discharge channel thereof comprises a resin containing a COP-based resin as the main component, with a stopper body part, which holds the rubber stopper and comprises a resin containing a COP-based resin as the main component, via the resin layers containing the respective COP-based resins as the main component; and at least the resin constituting the stopper body part contains a rubber component in an amount of not more than 30% by mass, or has, in the main chain, a molecular structure represented by general formula (1) [wherein R represents a hydrogen atom or an organic group having 1 to 20 carbon atoms; and n represents an integer equal to or greater than 1] and contains a PE-based resin in an amount of 30% by mass or less, and/or contains an antioxidant in an amount of 0.1% by mass or more and not more than 1.0% by mass.

    摘要翻译： 一种用于液体的容器的倾倒口嵌入一个允许注射针穿过的橡胶塞，其中：所述倾倒口是通过焊接端口部分形成的，至少其最内层形成排出 其通道包括含有COP基树脂作为主要成分的树脂，具有塞体部分，其通过包含各COP的树脂层保持橡胶塞并包含含有COP基树脂作为主要成分的树脂 基树脂为主要成分; 并且至少构成塞体部的树脂含有不超过30质量％的橡胶组分，或者在主链中具有由通式（1）表示的分子结构[其中R表示氢 原子或碳原子数为1〜20的有机基团; n表示1以上的整数]，含有30质量％以下的PE系树脂，和/或含有0.1质量％以上且不大于 1.0质量％。

    MULTILAYERED LIQUID CONTAINER
    10.
    发明申请
    MULTILAYERED LIQUID CONTAINER 有权
    多层液体容器

    公开(公告)号：US20110135223A1

    公开(公告)日：2011-06-09

    申请号：US13057439

    申请日：2009-07-27

    申请人： Toyoaki Suzuki ,  Koichi Miura ,  Atsushi Mio

    发明人： Toyoaki Suzuki ,  Koichi Miura ,  Atsushi Mio

    IPC分类号： B65D30/02 ,  B65D33/36

    CPC分类号： B65D75/5883 ,  A61J1/10 ,  A61J1/1475 ,  B32B27/32 ,  Y10T428/1352

    摘要： A multilayered liquid container having a discharge port welded under specified conditions to a sealant, which is constituted of a resin comprising a cycloolefin resin as a main component. The discharge port is composed of: an innermost layer constituted of a resin comprising a cycloolefin as a main component; and a surface layer whose main part is constituted of a resin comprising a specific type of polyethylene as a main component. According to the present invention, there can be provided a multilayered liquid container, which can prevent an effective component of a content fluid from being adsorbed onto or penetrating through not only the container body, but also the resin constituting the discharge port, and enables high temperature sterilization treatment, coupled with the discharge port having high welded strength and drop strength.

    摘要翻译： 一种多层液体容器，其具有在特定条件下焊接到由包含环烯烃树脂作为主要成分的树脂构成的密封剂的排出口。 排出口由以下物质构成：由以环烯为主要成分的树脂构成的最内层; 以及其主要部分由包含特定类型的聚乙烯作为主要成分的树脂构成的表面层。 根据本发明，可以提供一种多层液体容器，其能够防止含量流体的有效成分不仅吸附到或穿过容器主体，也可以渗透到构成排出口的树脂上，并且能够高 与排出口相结合，焊接强度高，落下强度高。