公开(公告)号：US10004453B2

公开(公告)日：2018-06-26

申请号：US15250469

申请日：2016-08-29

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Il-Joo Cho ,  Eui Sung Yoon ,  Hyogeun Shin ,  Uikyu Chae ,  Hyunjoo Jenny Lee

IPC: A61M5/32 ,  A61B5/00 ,  A61B5/04 ,  A61M5/158 ,  A61M39/10

CPC classification number: A61B5/4848 ,  A61B5/04001 ,  A61B5/6848 ,  A61B2562/028 ,  A61M5/158 ,  A61M39/105 ,  A61M2210/0693

Abstract: A neural probe structure has a probe having a microfluidic channel. The probe is inserted into an inside of a subject. A body to which the probe is fixed has a fluid entrance communicating with the microfluidic channel. A cover element is fixed to the body to cover the fluid entrance. The cover element has a connecting opening to which an external conduit is connected, and a fluid delivery channel extending such that the connecting opening and the fluid entrance are in fluid communication. A fluid fed from the external conduit flows along the fluid delivery channel, goes into the fluid entrance, and is delivered to the subject through the microfluidic channel.

公开(公告)号：US08838197B2

公开(公告)日：2014-09-16

申请号：US13670957

申请日：2012-11-07

Applicant: Korea Institute of Science and Technology

Inventor： Il Joo Cho ,  Eui Sung Yoon ,  Jei Won Cho ,  Myoung Gun Jeon ,  Yun Kyung Kim

IPC: A61B5/0478 ,  A61B5/00

CPC classification number: A61B5/0478 ,  A61B5/6868 ,  A61B2503/40 ,  A61B2503/42 ,  A61B2562/125 ,  A61B2562/18

Abstract: The micro probe according to an embodiment of the present disclosure includes: a probe portion made of a rigid material and serving as a portion inserted into the brain; a flexible portion connected to a distal end of the probe portion and made of a flexible material; a soluble portion coated on at least one surface of the flexible portion and made of a material which is dissolved by a solution in the cranium; and a body portion connected to the other end of the flexible portion whose one end is connected to the probe portion.

Abstract translation: 根据本公开的实施例的微型探针包括：由刚性材料制成并用作插入脑中的部分的探针部分; 柔性部分，其连接到探针部分的远端并由柔性材料制成; 所述可溶部分涂覆在所述柔性部分的至少一个表面上，并且由溶液溶解在所述颅骨中的材料制成; 以及主体部分，其连接到柔性部分的另一端，其一端连接到探针部分。

公开(公告)号：US11021586B2

公开(公告)日：2021-06-01

申请号：US15438215

申请日：2017-02-21

Applicant: Korea Institute of Science and Technology

Inventor： Nakwon Choi ,  Sohyun Kim ,  Sohyeon Jeong ,  Eui Sung Yoon ,  Changjoon Justin Lee ,  Il-Joo Cho

IPC: B29C43/18 ,  C08J7/043 ,  C08J7/04 ,  C12M3/00 ,  C12M1/12 ,  C12N5/00 ,  C12N5/09

Abstract: The present disclosure relates to an apparatus and a method for manufacturing a channel-coupled scaffold. The present disclosure provides a method for manufacturing a channel-coupled scaffold, which includes: (1) a step of compressing a first elastic substrate which includes a groove on the surface of the substrate to close the groove; (2) a step of loading a scaffold composition onto the closed groove; and (3) a step of restoring the elastic substrate. The present disclosure also provides an apparatus for manufacturing a channel-coupled scaffold, which includes: a first elastic substrate which includes a groove on the surface of the substrate and onto which a scaffold composition is loaded: and a compression module which compresses the width of the groove of the elastic substrate to close it. The apparatus or method may accumulate a microchannel controlling local mass transfer, and align a collagen fiber in the scaffold at the same time.

公开(公告)号：US20140009411A1

公开(公告)日：2014-01-09

申请号：US13749179

申请日：2013-01-24

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Il Joo CHO ,  Kyoung Hwan Na ,  Eui Sung Yoon ,  Jei Won Cho

IPC: G06F3/041

CPC classification number: G06F3/0412 ,  G06F3/011 ,  G06F3/016

Abstract: The tactile display device of the present disclosure includes: an actuator which is movable in a vertical direction when an electric current or a pneumatic force is applied thereto; and a body made of flexible material and having a receiving unit for receiving the actuator and a fluid channel allowing a pneumatic force from an outside to be transferred to the receiving unit, wherein a membrane made of flexible material and capable of vertical displacement is attached to an upper end of the receiving unit of the body, and the actuator is coupled to a lower portion of the membrane so that the membrane and the actuator have the same vertical displacement.

Abstract translation: 本公开的触觉显示装置包括：致动器，当向其施加电流或气动力时，可在垂直方向上移动; 以及由柔性材料制成的本体，并且具有用于容纳致动器的接收单元和允许来自外部的气动力传递到接收单元的流体通道，其中，由柔性材料制成且能够垂直移动的膜附接到 主体的接收单元的上端，并且致动器联接到膜的下部，使得膜和致动器具有相同的垂直位移。

公开(公告)号：US20190320941A1

公开(公告)日：2019-10-24

申请号：US16385244

申请日：2019-04-16

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Sungwook Yang ,  Eui Sung Yoon ,  Hoon Ryu ,  Hyeonjoo Im

IPC: A61B5/103 ,  A61B5/00 ,  G01L5/00

Abstract: An impact control system includes a supporting structure with gravity compensation mechanism, and a supporting bed which is supported by the supporting structure and supports an impact target. Here, the supporting structure includes an elastic element, a vertical support to which one end of the elastic element is fixed, a horizontal support to which the other end of the elastic element is fixed, and which is rotatable around a rotation axis disposed at one end of the horizontal support meeting an end of the vertical support, and a weight support part which is connected to the other end of the horizontal support and supports the supporting bed while contacting a lower surface of the supporting bed.

公开(公告)号：US09803167B2

公开(公告)日：2017-10-31

申请号：US14950710

申请日：2015-11-24

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Nakwon Choi ,  Eun-Mi Hur ,  Sohyun Kim ,  Sun-Kyoung Im ,  Eui Sung Yoon ,  Changjoon Justin Lee

IPC: B29C55/00 ,  C12M1/42 ,  B29C55/02 ,  B29C55/20 ,  B29C55/12 ,  C08J5/00 ,  A61L27/16 ,  A61L27/38 ,  A61L27/50

CPC classification number: C12M35/04 ,  A61L27/165 ,  A61L27/3804 ,  A61L27/3826 ,  A61L27/383 ,  A61L27/3834 ,  A61L27/50 ,  A61L2430/32 ,  B29C55/02 ,  B29C55/023 ,  B29C55/12 ,  B29C55/20 ,  C08J5/00

Abstract: The present disclosure relates to stretching apparatus and method for aligning microfibrils. Specifically, the present disclosure provides an apparatus for aligning microfibrils along a single direction, which includes: a first elastic substrate onto which a composition containing microfibrils is loaded; and a stretching module which stretches the width of the elastic substrate. In accordance with the apparatus the present disclosure, microfibrils or cells may be aligned along a particular direction simply by pulling and then releasing the elastic substrate. The present disclosure is also useful for culturing of the aligned cells because the physiological activity of the cells can be maintained and cytotoxicity can be prevented.